15 completed, 11 unknown, 6 terminated, 5 recruiting. 24 Not applicable, 7 Phase 2, 5 Phase 4, 1 Early Phase 1, 1 Phase 1.
Follow Esophageal Stenosis: new trials by email Literature Review of Esophageal Stenosis trials Research Report on Esophageal Stenosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Body Positioning on EndoFLIP Measurements: A Comparative Study of Supine and Left Lateral Decubitus Positions EndoFlip - Dysphagia, Esophageal Stricture | Not applicable | Recruiting | Johns Hopkins University | 25 | 2026-07-24 | 2026-08-24 |
| Treatment of Dysphagia in Patients With Dystrophic Epidermolysis Bullosa With Budesonide: a Retrospective Bicentric Study Nice - Paris St Louis / Necker (EBUDE Study) The retrospective data collected will be entered into an eCRF and then analyzed centrally - Recessive Dystrophic Epidermolysis Bullosa, Dysphagia | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Nice | 15 | 2026-07-01 | 2026-07-06 |
| Budesonide Following Endoscopic Dilatation of Esophageal Strictures in Children. Budesonide intervention - Esophageal Stricture | Not applicable | Not yet recruiting | Shaare Zedek Medical Center | 32 | 2026-05-01 | 2026-05-01 |
| Cohort Study on the Use of the BOUGIE CAP™ Device for the Treatment of Benign and Short Esophageal Strictures Esophageal Strictures | Recruiting | Hospices Civils de Lyon | 200 | 2026-01-04 | 2026-04-16 | |
| Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study Endoscopic Balloon Dilation - Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia | Not applicable | Recruiting | Boston Children's Hospital | 128 | 2025-10-28 | 2026-04-30 |
| An Innovative Endoscopic Cap for Dilating Benign Esophageal Strictures in Children BougieCap, Savary-Bougie (A) or balloon dilation (B) - Esophageal Stenosis, Esophageal Dilation | Not applicable | Recruiting | University Children's Hospital, Zurich | 40 | 2025-01-01 | 2024-12-11 |
| Tranilast Vs. Steroids to Prevent Esophageal Stricture (TAPES) After Endoscopic Resection for Superficial Neoplasms Tranilast, Dexamethasone - Esophageal Stricture, Esophageal Neoplasms | Phase 2 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 394 | 2025-01-01 | 2024-11-14 |
| Esophageal Replacement With a Decellularized Human Esophagus Graft Replacement of the esophagus with a decellularized human esophagus graft - Esophageal Stenosis | Phase 1 / Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 24 | 2024-11-01 | 2024-10-28 |
| Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus GIE Medical ProTractX3 TTS DCB, Control - Esophageal Stricture | Phase 3 | Recruiting | GIE Medical | 198 | 2023-12-01 | 2025-06-25 |
| Steroid Versus Mitomycin-C Use in Pediatric Benign Recurrent Esophageal Stricture Balloon Dilation + Topical Mitomycin, Balloon Dilation + Injection Triamcinolone - Esophageal Stricture | Not applicable | Completed | King Edward Medical University | 24 | 2023-07-01 | 2024-10-04 |
| Self-Assembling Matrix Forming Gel to Prevent Stricture Formation Purastat SAP gel application - Esophageal Stricture, Stricture | Completed | AdventHealth | 41 | 2022-09-19 | 2025-01-24 | |
| Anti-Migration System for Anti-reflux Oeso-gastric Stent (ANTIMIG) Gastroesophageal stent placement - Stent Migration, GastroEsophageal Cancer | Not applicable | Unknown | Société Française d'Endoscopie Digestive | 180 | 2022-09-01 | 2024-07-30 |
| Role of Topical Steroid Injection With Refractory Benign Esophageal Stricture Endoscopic Dilatation in Children Esophageal dilatation with steroids injection - Pediatric Disorder, Esophageal Diseases | Not applicable | Unknown | Mohammad Daboos | 21 | 2022-03-02 | 2024-07-23 |
| Local Triamcinolone Injection Combined With Fibrin Glue Spray in Preventing Esophageal Stricture After Big-range Endoscopic Submucosal Dissection for Esophageal Early Cancer Local triamcinolone injection combined with fibrin glue spray - Esophageal Stricture, Endoscopic Submucosal Dissection | Phase 2 | Completed | Sun Yat-Sen University Cancer Center | 20 | 2021-11-24 | 2025-02-21 |
| Feasibility and Therapeutic Potential of Free Fat Grafts in the Treatment of Esophageal Strictures (ESOGRAFT) Stricture dilation with CRE balloon, Autologous fat grafting - Esophageal Stricture, Fat Graft | Not applicable | Unknown | Hannes Kortekangas | 20 | 2021-08-15 | 2021-03-02 |
| The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children Triamcinolone Injection in treatment of refractory benign Esophageal Stricture in children - Esophageal Stricture | Phase 4 | Unknown | Assiut University | 20 | 2020-12-01 | 2020-10-27 |
| NKI Therapy Compared to Usual Care of Recurrent Esophagogastric Anastomotic Strictures NKI followed by EBD - Esophageal Stricture, Anastomotic Stenosis | Not applicable | Terminated | Radboud University Medical Center | 15 | 2020-09-14 | 2024-06-17 |
| Cryoablation for Benign Gastrointestinal Anastomotic Strictures Cryotherapy, Esophagogastroduodenoscopy with Balloon Dilatation - Esophageal Stricture, Duodenal Stricture | Not applicable | Unknown | University of Southern California | 124 | 2020-09-01 | 2020-05-05 |
| Balloon Dilation Methods for Benign Esophageal Stricture Standard Balloon Dilation, Progressive Balloon Dilation - Esophageal Stricture | Not applicable | Withdrawn | Samuel H Mardini | 2020-07-13 | 2022-11-23 | |
| Azygos Vein Preservation; Its Impact on Early Outcomes After Neonatal EA/TOF Repair EA/TOF primary repair with Azygos vein preservation, EA/TOF primary repair with Azygos vein sacrifice (disconnection) - Azygos Vein Preservation Versus Disconnection, Tracheo-Esophageal Fistula With Atresia of Esophagus | Not applicable | Completed | dr. Muhammad Abdelhafez Mahmoud, MD | 64 | 2020-04-10 | 2023-07-24 |
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Deglutition Disorders (9) · Esophageal Neoplasms (8) · Eosinophilic Esophagitis (4) · Barrett Esophagus (2) · Constriction, Pathologic (2) · Esophageal Atresia (2) · Esophageal Fistula (2) · Esophageal Perforation (2) · Esophageal atresia with or without tracheoesophageal fistula (2) · Head and Neck Neoplasms (2) · Anastomotic Leak (1) · Bites and Stings (1) · Bronchial Neoplasms (1) · Deception (1)
Digestive System Diseases (45) · Gastrointestinal Diseases (45) · Esophageal Diseases (44) · Neoplasms (10) · Neoplasms by Site (9) · Otorhinolaryngologic Diseases (9) · Pharyngeal Diseases (9) · Digestive System Neoplasms (8) · Gastrointestinal Neoplasms (8) · Head and Neck Neoplasms (7) · Pathological Conditions, Anatomical (7) · Pathological Conditions, Signs and Symptoms (7) · Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Eosinophilia (4)
Mitomycin (3) · Steroids (3) · Prednisolone (2) · Budesonide (1) · Cryotherapy (1) · Dexamethasone (1) · Dilatation (1) · Endoscopy, Digestive System (1) · Methylprednisolone (1) · Prednisone (1) · Stents (1) · Triamcinolone (1) · tranilast (1)
AdventHealth (2) · Assistance Publique - Hôpitaux de Paris (2) · Cook Group Incorporated (2) · GIE Medical (2) · Johns Hopkins University (2) · Mayo Clinic (2) · Ajou University School of Medicine (1) · Assiut University (1) · Boston Children's Hospital (1) · Centre Hospitalier Universitaire de Nice (1) · E-DA Hospital (1) · Fauze Maluf Filho (1) · Federal University of São Paulo (1) · Foundation for Liver Research (1) · Fox Chase Cancer Center (1)
United States (16) · Brazil (3) · China (3) · France (3) · Netherlands (3) · Belgium (2) · Egypt (2) · Italy (2) · South Korea (2) · Switzerland (2) · Australia (1) · Israel (1) · Pakistan (1) · Paraguay (1) · Spain (1)
Ahmed Elshamy, MD (1) · Alain Schoepfer, Dr (1) · Barham K Abu Dayyeh, MD (1) · Calies Menard-Katcher, MD (1) · Dennis Yang, MD (1) · Divyanshoo Kohli, MD (1) · Gregory G Ginsberg, MD (1) · Jessica Yasuda, MD (1) · Jin Hong Kim (1) · John Vargo, M.D., M.P.H. (1) · Kenneth Ng, DO (1) · Kenneth Wang, MD (1) · Marco J Bruno, M.D., Prof (1) · Meidong Xu, PhD (1) · Michael Bourke (1)
PMID 16771943, PMID 19935783, PMID 19938199, PMID 29883979, PMID 29895072, PMID 35708794, PMID 38583540, PMID 41646070, PMID 41926323
UL1TR001082 (1)