6 completed, 6 unknown, 1 not yet recruiting, 1 recruiting. 6 Phase 2, 4 Early Phase 1, 3 Phase 4, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 3, Unknown 2, Not yet recruiting 1 |
| Early Phase 1 | 4 | Unknown 3, Recruiting 1 |
| Phase 4 | 3 | Completed 2, Unknown 1 |
| Phase 1 | 1 | Withdrawn 1 |
| Phase 3 | 1 | Completed 1 |
Follow tranilast: new trials by email Literature Review of tranilast trials Research Report on tranilast
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study on the Effectiveness of Tranilast in the Treatment of Medium to Large Volume Benign Prostatic Hyperplasia alpha receptor antagonist, Low dose Tranilast, High dose Tranilast - Prostatic Hypertrophy, Benign | Early Phase 1 | Recruiting | Yifeng Jing | 30 | 2025-01-20 | 2026-01-08 |
| Tranilast Vs. Steroids to Prevent Esophageal Stricture (TAPES) After Endoscopic Resection for Superficial Neoplasms Tranilast, Dexamethasone - Esophageal Stricture, Esophageal Neoplasms | Phase 2 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 394 | 2025-01-01 | 2024-11-14 |
| Efficacy and Safety of Tranilast Combined With Minocycline in the Treatment of Rosacea minocycline, tranilast - Rosacea | Phase 4 | Unknown | Second Affiliated Hospital of Xi'an Jiaotong University | 45 | 2023-10-16 | 2024-03-12 |
| Tranilast as a Radiosensitizer in Reradiation of Nasopharyngeal Carcinoma Tranilast - Nasopharyngeal Carcinoma, Recurrent Cancer | Phase 2 | Unknown | Jian Guan | 18 | 2022-07-20 | 2023-10-06 |
| Effect of Inflammasome Inhibitor on hsCRP in Patients After PCI Colchicine, Tranilast, Oridonin - NLRP3, hsCRP | Phase 4 | Completed | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 132 | 2021-11-15 | 2023-02-08 |
| A Clinical Study of Tranilast in the Treatment of Cryopyrin-Associated Periodic Syndrome (CAPS) Tranilast - Cryopyrin-Associated Periodic Syndromes | Phase 2 | Unknown | Peking Union Medical College Hospital | 71 | 2019-05-23 | 2019-06-04 |
| A Clinical Study of Tranilast in the Treatment of Scleredema Diabeticorum Tranilast - Scleredema Adultorum | Early Phase 1 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 56 | 2018-06-01 | 2018-05-01 |
| A Clinical Study of Tranilast in the Treatment of Sarcoidosis Tranilast - Sarcoidosis | Early Phase 1 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 56 | 2018-05-01 | 2018-05-17 |
| A Clinical Study of Tranilast in the Treatment of Mucinoses Tranilast - Mucinoses | Early Phase 1 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 56 | 2018-04-01 | 2018-04-06 |
| Study of Tranilast Alone or in Combination With Allopurinol in Subjects With Hyperuricemia Tranilast, Allopurinol, Combination - Tranilast and Allopurinol - Gout, Hyperuricemia | Phase 2 | Completed | Nuon Therapeutics, Inc. | 24 | 2010-01-01 | 2011-01-06 |
| Study of Tranilast Alone or in Combination With Febuxostat in Patients With Hyperuricemia Tranilast, Febuxostat, Combination - Tranilast and Febuxostat - Gout, Hyperuricemia | Phase 2 | Completed | Nuon Therapeutics, Inc. | 24 | 2009-09-01 | 2011-01-06 |
| Safety and Efficacy Study of Tranilast in Patients With Active Rheumatoid Arthritis (RA) Tranilast, Placebo - Active Rheumatoid Arthritis | Phase 2 | Completed | Nuon Therapeutics, Inc. | 250 | 2009-03-01 | 2011-01-06 |
| Evaluation of Tranilast to Treat Pterygium Before Excision Tranilast, and Tissucol, Beriplast P - Pterygium | Phase 3 | Completed | Gildasio Castello de Almeida Junior | 32 | 2009-02-01 | 2012-04-18 |
| Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA) Tranilast, Placebo comparator - Rheumatoid Arthritis | Phase 1 | Withdrawn | Imperial College London | 2008-09-01 | 2015-05-28 | |
| Efficacy Investigation Study of Olopatadine Hydrochloride Ophthalmic Solution Using OHIO Chamber in Patients With Seasonal Allergic Rhinitis (SAR) Olopatadine 0.1%, Tranilast 0.5%, Placebo (Olopatadine) - Allergic Conjunctivitis | Phase 4 | Completed | Alcon Research | 50 | 2008-07-01 | 2012-06-04 |
Arthritis, Rheumatoid (2) · Gout (2) · Hyperuricemia (2) · Conjunctivitis (1) · Conjunctivitis, Allergic (1) · Cryopyrin-Associated Periodic Syndromes (1) · Esophageal Neoplasms (1) · Esophageal Stenosis (1) · Mucinoses (1) · Nasopharyngeal Carcinoma (1) · Prostatic Hyperplasia (1) · Pterygium (1) · Recurrence (1) · Rosacea (1) · Sarcoidosis (1)
Nuon Therapeutics, Inc. (3) · The First Affiliated Hospital with Nanjing Medical University (3) · Alcon Research (1) · Gildasio Castello de Almeida Junior (1) · Imperial College London (1) · Jian Guan (1) · Peking Union Medical College Hospital (1) · Second Affiliated Hospital of Xi'an Jiaotong University (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · Yifeng Jing (1)
China (6) · United States (3) · Argentina (1) · Brazil (1) · Bulgaria (1) · Czechia (1) · Germany (1) · Mexico (1) · Serbia (1) · United Kingdom (1)
Acacio AS Lima Filho, MD (1) · Gildasio C Almeida Jr, Prof Dr (1) · Guan Jian, Ph.D. (1) · Hongmei Song (1) · Michael Kitt, MD (1) · Peter C Taylor, PhD (1) · Reinaldo Azoubel, Prof Dr (1) · Sidney JF Sousa, Prof Dr (1) · Vinicius Tadeu NS Nascimento, Student (1) · Weihui Zeng (1) · Yue Yu, Dr. (1)
PMID 12297693, PMID 15307986, PMID 18053915, PMID 18071725, PMID 25714528, PMID 27718519, PMID 27861741, PMID 31392722, PMID 34476755, PMID 34840653, PMID 37108184