7 completed, 6 unknown, 4 recruiting, 2 suspended. 4 Not applicable, 2 Phase 4, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Recruiting 3, Completed 1 |
| Phase 4 | 2 | Unknown 2 |
| Early Phase 1 | 1 | Completed 1 |
Follow Epigenetics: new trials by email Literature Review of Epigenetics trials Research Report on Epigenetics
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pesticides and Infertility: Oxidative Stress Via Circulating Cell-free DNA and Gut/Genital Microbiome Signatures in Women With Endometriosis Circulating DNA analysis, Vaginal microbiota analysis, Endometrial microbiota analysis - Endometriosis, Infertility | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 160 | 2026-02-27 | 2026-05-15 |
| Methylated Biomarkers of Smoking as a Selection Tool in Participants for Lung Cancer Screening DNA-methylation in saliva - Epigenetics, DNA Methylation | Not applicable | Recruiting | University Hospital, Antwerp | 1000 | 2025-10-04 | 2026-06-08 |
| Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies Flexiquit Smoking Cessation Intervention - Smoking Cessation, Smoking Cessation Intervention | Unknown | University of Cyprus | 200 | 2023-11-01 | 2024-06-25 | |
| BCG-induced Epigenetic Modifications in the NEXT Generation BCG-Vaccine SSI [Statens Serum Institut]) Danish strain 1331, Placebo - Trained Immunity, BCG Vaccine | Phase 4 | Unknown | Radboud University Medical Center | 36 | 2023-10-02 | 2024-04-10 |
| Methylation, mIcrobiome, NUtritional sTatus, and dEvelopment of Stunted Children Stunting, Development, Child | Unknown | SEAMEO Regional Centre for Food and Nutrition | 300 | 2023-04-05 | 2024-07-03 | |
| Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity saliva tube - Oral Squamous Cell Carcinoma, Maxillo-facial Surgery | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 60 | 2022-03-03 | 2026-05-13 |
| Biological Underpinnings of Socio-emotional Regulation in Preterm Infants and Healthy Controls DNA methylation of target genes, EEG acquisition - Preterm Birth, Parent-Child Relations | Completed | IRCCS Eugenio Medea | 76 | 2021-07-13 | 2026-11-05 | |
| Topical-RAPA Use in Inflammation Reversal and Re-setting the Epigenetic Clock Rapamycin Topical Ointment, Placebo - Aging, Epigenetics | Early Phase 1 | Completed | The University of Texas Health Science Center at San Antonio | 22 | 2021-04-28 | 2023-07-19 |
| Emotional Regulation in Children With ND: the Role of Genomic Variation, Proteomic Patterns, and Early Experience DNA methylation analysis, Proteomics analysis, Still Face Paradigm - Neurodevelopmental Disabilities, Emotional Regulation | Unknown | IRCCS Eugenio Medea | 248 | 2021-04-07 | 2023-10-18 | |
| LINE-1 and Alu Methylation Levels Among Middle Aged Women With Low Cardiovascular Risk Profile in Respect of Menopausal Hot Flashes Polysomnography, Skin conductance, ALU and LINE-1 DNA methylation analysis - Hot Flashes, Sleep | Suspended | Istanbul University - Cerrahpasa | 30 | 2020-12-01 | 2025-05-02 | |
| Biomarker Study to Evaluate Correlations Between Epigenetic Aging and NAD+ Levels in Healthy Volunteers Biomarker study - Epigenetics | Suspended | Elysium Health | 170 | 2019-12-19 | 2023-02-15 | |
| Epigenetics and Protective Factors in the Preterm Infant DNA methylation of target genes, Functional Magnetic Resonance Imaging (fMRI) acquisition - Preterm Birth, Parent-Child Relations | Unknown | IRCCS Eugenio Medea | 94 | 2019-01-01 | 2023-10-18 | |
| Early Childhood Obesity Programming by Intrauterine Growth Restriction Childhood Obesity, Epigenetics | Completed | Montefiore Medical Center | 163 | 2018-09-01 | 2026-08-31 | |
| Examining the Effects of Juice Fasting Juice, Caloric restriction via Plant-based meals, Plant-based meal - Epigenetics, Microbiome | Not applicable | Completed | Northwestern University | 24 | 2018-07-10 | 2020-02-27 |
| The Epigenetic Modification in OPRM1 on Postoperative Analgesia and Side Effect Induced by Sufentanil Sufentanil, dexmedetomidine, propofol - Epigenetics | Phase 4 | Unknown | Huazhong University of Science and Technology | 100 | 2017-02-06 | 2017-05-01 |
| DNA Methylation Profile of the SOCS-1 Gene Promoter in Smokers Patients With Chronic Periodontitis. oral epithelial cells obtained by rinsing with 3% sucrose - Periodontal Diseases, Epigenetics | Completed | University of Sao Paulo | 60 | 2016-06-06 | 2017-12-13 | |
| Foetal Exposure and Epidemiological Transition: Role of Anaemia in Early Life for Non-communicable Diseases Later Anemia and Pregnancy, Metabolism and Foetal Growth | Completed | University of Copenhagen | 1748 | 2014-07-01 | 2019-09-30 | |
| Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study PCOS, Offspring, Adult | Recruiting | Guangzhou Women and Children's Medical Center | 2000 | 2012-02-01 | 2024-02-26 | |
| Effects of Maternal Folate and Folic Acid Supplementation on DNA Methylation in the Newborn Infant Pregnancy, Maternal Nutrition | Completed | Unity Health Toronto | 368 | 2010-09-01 | 2014-09-19 |
Premature Birth (2) · Anemia (1) · Cardiovascular Diseases (1) · Emotional Regulation (1) · Endocrine System Diseases (1) · Endometriosis (1) · Growth Disorders (1) · Hot Flashes (1) · Hyperandrogenism (1) · Infertility (1) · Insulin Resistance (1) · Noncommunicable Diseases (1) · Pediatric Obesity (1) · Periodontal Diseases (1) · Smoking (1)
Female Urogenital Diseases and Pregnancy Complications (4) · Pathological Conditions, Signs and Symptoms (4) · Urogenital Diseases (4) · Behavior (3) · Female Urogenital Diseases (2) · Nutritional and Metabolic Diseases (2) · Obstetric Labor Complications (2) · Obstetric Labor, Premature (2) · Pathologic Processes (2) · Pregnancy Complications (2) · Signs and Symptoms (2) · 46, XX Disorders of Sex Development (1) · Adrenogenital Syndrome (1) · Body Weight (1) · Carcinoma (1)
DNA Methylation (2) · Dexmedetomidine (1) · Galvanic Skin Response (1) · Magnetic Resonance Imaging (1) · Petrolatum (1) · Polysomnography (1) · Propofol (1) · Remifentanil (1) · Rocuronium (1) · Sevoflurane (1) · Sucrose (1) · Sufentanil (1) · parecoxib (1)
IRCCS Eugenio Medea (3) · Centre Hospitalier Universitaire, Amiens (2) · Elysium Health (1) · Guangzhou Women and Children's Medical Center (1) · Huazhong University of Science and Technology (1) · Istanbul University - Cerrahpasa (1) · Montefiore Medical Center (1) · Northwestern University (1) · Radboud University Medical Center (1) · SEAMEO Regional Centre for Food and Nutrition (1) · The University of Texas Health Science Center at San Antonio (1) · Unity Health Toronto (1) · University Hospital, Antwerp (1) · University of Copenhagen (1) · University of Cyprus (1)
United States (4) · Italy (3) · China (2) · France (2) · Belgium (1) · Brazil (1) · Canada (1) · Cyprus (1) · Indonesia (1) · Netherlands (1) · Tanzania (1) · Turkey (Türkiye) (1)
Annemiek Snoeckx, MD, PhD (1) · Arthur B. Novaes Junior, DDS, PhD (1) · Dean L Kellogg, Jr., MD, PhD (1) · Deborah O'Connor, RD, PhD (1) · Ellen Kraig, PhD (1) · Ipek Betul Ozcivit Erkan, MD (1) · Jeffrey Guptill, MD (1) · Melinda Ring, MD, FACP (1) · Mwelecele N Malecela, PHd (1) · Sandra Reznik, MD (1) · Umi Fahmida, Dr. (1) · Xiu Qiu, PhD (1) · Xu Hui (1) · Young-In Kim, MD (1)
PMID 25972528, PMID 26063067, PMID 26269367, PMID 27075906, PMID 28321694, PMID 30562390, PMID 30590576, PMID 31014291, PMID 31562504, PMID 35021220, PMID 38059784, PMID 38997672, PMID 42629565
2023 (1), R01HD092533 (1), R16GM145586 (1), R21AG068731 (1), S10OD030286 (1)