24 completed, 8 recruiting, 7 unknown, 5 not yet recruiting. 13 Not applicable, 2 Phase 1, 2 Phase 2, 2 Phase 4, 1 Phase 3.
Follow Encephalopathy: new trials by email Literature Review of Encephalopathy trials Research Report on Encephalopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Against Chikungunya Virus and Neonatal Infection plasma transfusion : PC-CHIK-V - Chikungunya Virus Infection, Neonatal | Not applicable | Recruiting | Centre Hospitalier Universitaire de la Réunion | 60 | 2027-08-01 | 2026-09-15 |
| Prospective Observational Multimodal Neuromonitoring in Adult NSICU Patients Subarachnoid Hemorrhage, Aneurysmal, Brain Injuries, Traumatic | Not yet recruiting | University of Texas Southwestern Medical Center | 300 | 2027-07-01 | 2026-10-23 | |
| This Multicentre Study Compares aCUP-E With Standard Electrodes During aEEG Monitoring in NICU Newborns at Risk of Encephalopathy, Assessing Recording Quality, Reliability, Ease of Use and Safety. Encephalopathy | Not yet recruiting | Institut Investigacio Sanitaria Pere Virgili | 35 | 2026-10-15 | 2026-11-06 | |
| EEG Abnormalities as Predictor of Outcome in Pediatric Encephalopathy Encephalopathy, Brain Diseases | Not yet recruiting | Assiut University | 147 | 2026-09-10 | 2026-09-17 | |
| Use of Gocovri to Improve Disability Due to Radiation Encephalopathy Gocovri (extended-release amantidine) - Encephalopathy, Radiation Effect | Phase 2 | Not yet recruiting | Weill Medical College of Cornell University | 24 | 2026-09-01 | 2026-08-03 |
| The Aim of the Present Study is to Determine Outcome Predictors in Children Who Were Diagnosed as Acute Disseminated Encephalomyelitis (ADEM). Acute Disseminated Encephalomyelitis, Encephalomyelitis | Not yet recruiting | Assiut University | 25 | 2026-03-29 | 2026-04-20 | |
| Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy Quest AD-Detect blood test - Alzheimer Dementia, Alzheimer Disease | Not applicable | Recruiting | Covenant Health, US | 30 | 2025-06-10 | 2025-10-29 |
| CoMind Early Feasibility Study Intracranial Pressure, Intracranial Pressure Changes | Recruiting | CoMind Technologies Limited | 581 | 2024-11-27 | 2026-10-30 | |
| Initiating Pediatric Palliative Care in ACT Group 4 Collection of data from the patient's medical file - Encephalopathy, Cerebral Palsy | Completed | Assistance Publique - Hôpitaux de Paris | 126 | 2023-12-22 | 2025-09-12 | |
| Cerebral Pulsatility Index Compared To Mean Arterial Blood Pressure Guided Protocol In Sepsis Induced Encephalopathy: Transcranial doppler pulsatility index guided protocol, Mean arterial blood pressure guided protocol - Sepsis, Norepinephrine | Not applicable | Completed | Tanta University | 112 | 2023-05-01 | 2024-08-06 |
| Automating Delirium Severity in the ICU Intensive Care Unit Delirium, Encephalopathy | Recruiting | Mayo Clinic | 400 | 2023-01-15 | 2026-04-08 | |
| Erythropoietin for Neonatal Encephalopathy in LMIC (EMBRACE Trial) Erythropoietin, Supportive neonatal intensive care - Encephalopathy, Erythropoietin | Phase 3 | Recruiting | Imperial College London | 504 | 2022-12-31 | 2024-03-19 |
| Prevalence of Encephalopathy in Patients With Inflammatory Bowel Diseases Inflammatory Bowel Diseases, Ulcerative Colitis Chronic | Unknown | Centre of Postgraduate Medical Education | 80 | 2022-10-01 | 2023-04-27 | |
| Build a Decision Aid Tool to Help Emergency Intensive Care Specialists in the Context of Hypoxic Ischemic Encephalopathy Decision of hypothermia - Encephalopathy | Completed | Assistance Publique - Hôpitaux de Paris | 106 | 2022-09-08 | 2024-02-05 | |
| eegCap Application in Paediatrics wiTh redUced GCS in REsus Status Epilepticus, Altered Level of Consciousness | Completed | University College Cork | 20 | 2021-07-05 | 2023-05-16 | |
| Neuroimmunology Registry and Biobank Encephalopathy, Psychosis | Recruiting | Charite University, Berlin, Germany | 300 | 2021-02-01 | 2025-05-06 | |
| WHO Covid 19 - Neurological Abnormalities in SARS-CoV-2 ICU Patients SARS-CoV-2 Infection, Intensive Care Unit Patient | Unknown | University Hospital, Clermont-Ferrand | 20 | 2020-10-13 | 2020-12-01 | |
| Study to Assess and Monitor Brain Activity EEG - Delirium, Encephalopathy | Unknown | Massachusetts General Hospital | 350 | 2020-08-10 | 2022-08-08 | |
| Neurocognitive Impairment in Pediatric Patients With Meningoencephalitis and Sepsis-associated Encephalopathy Critical Illness, Brain Injuries | Completed | University of Rostock | 42 | 2020-08-03 | 2022-11-03 | |
| Effects of Large Tidal Volumes Despite Minimal Inspiratory Support in Spontaneously Ventilated Intubated Resuscitation Patients. Pathophysiological Exploratory Study. Multiparametric mesurements - Invasive Mechanical Ventilation, Ventilator-Induced Lung Injury | Not applicable | Unknown | University Hospital, Clermont-Ferrand | 30 | 2020-06-21 | 2021-09-28 |
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Brain Diseases (47) · Delirium (5) · Seizures (5) · Critical Illness (4) · Epilepsy (4) · Asphyxia Neonatorum (3) · COVID-19 (3) · Fibrosis (3) · Liver Cirrhosis (3) · Sepsis (3) · Alzheimer Disease (2) · Brain Injuries, Traumatic (2) · Cerebral Hemorrhage (2) · Cerebral Palsy (2) · Congenital Abnormalities (2)
Nervous System Diseases (47) · Central Nervous System Diseases (46) · Pathological Conditions, Signs and Symptoms (28) · Pathologic Processes (16) · Signs and Symptoms (16) · Neurologic Manifestations (15) · Mental Disorders (11) · Infections (10) · Neurobehavioral Manifestations (9) · Neurocognitive Disorders (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Digestive System Diseases (7) · Disease Attributes (6) · RNA Virus Infections (6) · Virus Diseases (6)
Electroencephalography (2) · Amantadine (1) · Diffusion Tensor Imaging (1) · Electroretinography (1) · Erythropoietin (1) · Exome (1) · Foscarnet (1) · Ganciclovir (1) · Hematologic Tests (1) · Magnetic Resonance Imaging (1) · Oximetry (1) · Tomography, X-Ray Computed (1) · Xenon (1) · enzalutamide (1)
Assistance Publique - Hôpitaux de Paris (4) · University of Rostock (3) · Assiut University (2) · Imperial College London (2) · Mayo Clinic (2) · Sharp HealthCare (2) · University Hospital, Clermont-Ferrand (2) · Centre Hospitalier Universitaire de la Réunion (1) · Centre of Postgraduate Medical Education (1) · Charite University, Berlin, Germany (1) · Children's Hospital of Fudan University (1) · CoMind Technologies Limited (1) · Corewell Health West (1) · Covenant Health, US (1) · F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica (1)
United States (18) · France (10) · Germany (4) · Egypt (2) · Poland (2) · United Kingdom (2) · Austria (1) · Bangladesh (1) · Brazil (1) · China (1) · Colombia (1) · French Guiana (1) · India (1) · Ireland (1) · Italy (1)
Johannes Ehler, MD (2) · Mary J Harbert, MD (2) · Amit Mathur (1) · Anna Pietrzak, MD (1) · Arnulf Ferlitsch, MD (1) · Barbara Koenig, PhD (1) · Chao Chen, PhD, MD (1) · Charles W Hogue, MD (1) · Clifford D (1) · Dale Needham, MD, PhD (1) · David A Edwards, FMedSci (1) · Deirdre Murray (1) · Denis Azzopardi, MD; FRCPCH (1) · Eyal Y Kimchi, MD, PhD (1)
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U01HG009599 (1)