19 completed, 7 recruiting, 7 unknown, 1 enrolling by invitation. 34 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 34 | Completed 19, Recruiting 7, Unknown 7, Enrolling by invitation 1 |
Follow Disorders of Sex Development: new trials by email Literature Review of Disorders of Sex Development trials Research Report on Disorders of Sex Development
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination Osilodrostat and Cabergoline in Cushing's Disease osilodrostat, osilodrostat and cabergoline - Cushing Disease Due to Increased ACTH Secretion | Phase 4 | Enrolling by invitation | University of Basrah | 50 | 2026-05-11 | 2026-05-22 |
| Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS) Osilodrostat (Isturisa) - Mild Autonomous Cortisol Secretion (MACS) | Phase 4 | Recruiting | Johns Hopkins University | 10 | 2026-02-02 | 2026-10-23 |
| Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome Micronized progesterone 200 MG, Micronized Progesterone 100 MG - Turner Syndrome, Primary Ovarian Insufficiency (Poi) | Phase 4 | Recruiting | Children's Mercy Hospital Kansas City | 40 | 2025-07-31 | 2026-08-25 |
| Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian Syndrome Myo-Inositol and D-Chiro-Inositol Combination Therapy, placebo (folic acid) - Polycystic Ovary Syndrome (PCOS), Myo-inositol | Phase 4 | Completed | Nishtar Medical University | 60 | 2025-06-01 | 2026-07-14 |
| Tirzepatide in PWS, HO and GNSO Tirzepatide - Prader-Willi Syndrome, Hypothalamic Obesity | Phase 4 | Recruiting | Grace Kim | 36 | 2025-05-01 | 2025-09-16 |
| Klinefelter Syndrome and Testosterone Treatment in Puberty Testosterone gel, Placebo - Klinefelter Syndrome | Phase 4 | Recruiting | Lise Aksglæde | 32 | 2024-08-15 | 2025-02-19 |
| Interrogating Fatty Acid Metabolism Impairment and Clinical Correlates in Males with Klinefelter Syndrome Fenofibrate 145 mg - Klinefelter Syndrome | Phase 4 | Unknown | University of Colorado, Denver | 44 | 2022-11-03 | 2024-10-16 |
| Long Term Effects of Oral Versus Transdermal Estrogen Replacement Therapy in Turner Syndrome 17-beta estradiol - Turner Syndrome, Hypogonadism; Ovarian | Phase 4 | Recruiting | Aarhus University Hospital | 50 | 2021-11-29 | 2024-08-26 |
| Determining Dose Equivalence Between Oral and Transdermal Estrogen Treatment in Women With Turner Syndrome 17-beta estradiol - Turner Syndrome, Hypogonadism; Ovarian | Phase 4 | Recruiting | Aarhus University Hospital | 50 | 2021-11-29 | 2024-08-23 |
| Comparisons of Different Forms of Glucocorticoid on the Recovery of Reproductive Function in Patients With 21α-hydroxylase Deficiency Hydrocortisone, Prednisone, Dexamethasone - Congenital Adrenal Hyperplasia | Phase 4 | Unknown | Shanghai Jiao Tong University School of Medicine | 120 | 2020-10-01 | 2020-09-02 |
| Continuous Versus Cyclical OCP Use in PCOS Yasmin - Polycystic Ovary Syndrome | Phase 4 | Completed | University of California, San Francisco | 51 | 2019-04-01 | 2025-11-14 |
| Efficacy and Safety of Long Term Use of hCG or hCG Plus hMG in Males With Isolated Hypogonadotropic Hypogonadism (IHH) Human Chorionic Gonadotropin, human menopausal gonadotropin - Isolated Hypogonadotropic Hypogonadism, Kallmann Syndrome | Phase 4 | Unknown | Tongji Hospital | 210 | 2018-10-18 | 2020-04-08 |
| TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY Testosterone Cypionate 200 Milligram/Milliliter Injectable Solution, Placebo injectable saline - Klinefelter Syndrome | Phase 4 | Completed | University of Colorado, Denver | 72 | 2017-11-06 | 2022-05-06 |
| Ovarian Response to Recombinant Follicle Stimulating Hormone in Women With PCOS Recombinant Follicle Stimulating Hormone - Polycystic Ovary Syndrome, Healthy | Phase 4 | Completed | University of California, San Diego | 33 | 2017-10-02 | 2021-09-08 |
| Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment Conventional Glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone), Dual release hydrocortisone (plenadren) - Congenital Adrenal Hyperplasia | Phase 4 | Recruiting | Federico II University | 150 | 2016-08-11 | 2025-09-16 |
| Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj. Somatropin - Short Stature, Idiopathic, Infant, Small for Gestational Age | Phase 4 | Completed | LG Life Sciences | 116 | 2016-08-11 | 2019-01-03 |
| Human Menopausal Gonadotropin Combining With Human Chorionic Gonadotropin Treat Congenital Hypogonadotropic Hypogonadism Human Menopausal Gonadotropin, Human Chorionic Gonadotropin - Kallmann Syndrome, Hypogonadotropic Hypogonadism | Phase 4 | Unknown | Beijing Children's Hospital | 40 | 2016-08-01 | 2016-08-26 |
| Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment testosterone cypionate 200mg/ml - Klinefelter Syndrome | Phase 4 | Completed | University of Colorado, Denver | 20 | 2015-05-08 | 2020-04-15 |
| Treatment of Obesity With Topiramate in Patients With Polycystic Ovary Syndrome Topiramate, Placebo - Obesity, Polycystic Ovary Syndrome | Phase 4 | Unknown | Hospital de Clinicas de Porto Alegre | 80 | 2014-05-01 | 2020-07-01 |
| Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants 20 mcg ethinylestradiol /3 mg drospirenone, 20 mcg ethinylestradiol/3 mg drospirenone and Selmevit, 30 mcg ethinylestradiol/3 mg drospirenone - Polycystic Ovarian Syndrome, Hyperandrogenism | Phase 4 | Unknown | Tyumen State Medical Academy | 200 | 2013-12-01 | 2014-11-21 |
Showing 20 of 34. Sign in to see all of them.
Turner Syndrome (13) · Hyperandrogenism (9) · Polycystic Ovary Syndrome (7) · Hypogonadism (6) · Klinefelter Syndrome (4) · Adrenal Hyperplasia, Congenital (3) · Dwarfism, Pituitary (3) · Genetic Diseases, Inborn (3) · Kallmann Syndrome (3) · Menstruation Disturbances (3) · Obesity (3) · Amenorrhea (2) · Hypertension (2) · Primary Ovarian Insufficiency (2) · Sexual Infantilism (2)
Congenital Abnormalities (34) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (34) · Endocrine System Diseases (34) · Female Urogenital Diseases (34) · Female Urogenital Diseases and Pregnancy Complications (34) · Gonadal Disorders (34) · Male Urogenital Diseases (34) · Urogenital Abnormalities (34) · Urogenital Diseases (34) · Genetic Diseases, Inborn (21) · Chromosome Disorders (18) · Sex Chromosome Disorders (17) · Sex Chromosome Disorders of Sex Development (17) · Cardiovascular Diseases (15)
Human Growth Hormone (6) · Estradiol (4) · drospirenone and ethinyl estradiol combination (3) · Chorionic Gonadotropin (2) · Cyproterone acetate, ethinyl estradiol drug combination (2) · Dexamethasone (2) · Ethinyl Estradiol (2) · Menotropins (2) · Osilodrostat (2) · Prednisone (2) · estradiol, estriol drug combination (2) · Blood Specimen Collection (1) · Cabergoline (1) · Cortisone (1) · Cyproterone Acetate (1)
Merck KGaA, Darmstadt, Germany (3) · Novo Nordisk A/S (3) · University of Colorado, Denver (3) · Aarhus University Hospital (2) · Shanghai Jiao Tong University School of Medicine (2) · AGUNCO Obstetrics and Gynecology Centre (1) · Beijing Children's Hospital (1) · Children's Mercy Hospital Kansas City (1) · Eli Lilly and Company (1) · Federico II University (1) · Fundação Educacional Serra dos Órgãos (1) · Grace Kim (1) · Hospital Universitario Ramon y Cajal (1) · Hospital de Clinicas de Porto Alegre (1) · Johns Hopkins University (1)
United States (10) · France (5) · China (4) · Denmark (4) · Italy (4) · Spain (3) · Argentina (2) · Brazil (2) · Canada (2) · Germany (2) · Russia (2) · Sweden (2) · United Kingdom (2) · Australia (1) · Austria (1)
Claus H Gravholt, Professor (2) · Shanlee M Davis, MD (2) · Abbas A Mansour (1) · Amir Hamrahian, MD (1) · Carlos P Nunes, M.D. (1) · Carlos RB Gama, M.D. (1) · Chunxiu Gong, doctor (1) · Gilles Della Corte (1) · Haider A Alidrisi (1) · Heather Huddleston, MD (1) · Ibrahim H Hussein, MD (1)
PMID 10518081, PMID 10599727, PMID 10599729, PMID 12466334, PMID 12629094, PMID 15900109, PMID 17536071, PMID 18375410, PMID 18997670, PMID 20730705, PMID 21398400, PMID 21880799, PMID 23567489, PMID 23678038, PMID 23737664, PMID 25825944, PMID 26340968, PMID 27454103, PMID 28887710, PMID 29510982, PMID 29618660, PMID 30571546, PMID 30817193, PMID 31206616, PMID 31613320, PMID 31908426, PMID 33813517, PMID 34045667, PMID 35220871, PMID 3536461, PMID 35817047, PMID 36952249, PMID 37318239, PMID 37801655, PMID 39062179, PMID 39086899, PMID 40090688, PMID 6135282, PMID 8923853
2009 (1), 2023 (1), K12HD001259 (1), K23HD092588 (1), P50HD012303 (1), UL1TR001082 (1)