474 unknown. 474 Phase 3, 99 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 474 | Unknown 474 |
| Phase 2 | 99 | Unknown 99 |
Follow Digestive System Neoplasms: new trials by email Literature Review of Digestive System Neoplasms trials Research Report on Digestive System Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis celecoxib monotherapy, celecoxib and metformin combination - Familial Adenomatous Polyposis | Phase 3 | Unknown | Yonsei University | 28 | 2024-08-13 | 2024-08-09 |
| Aprepitant Plus Granisetron and Dexamethasone for the Prevention of Vomiting in Patients With HAIC Therapy for HCC Aprepitant in combination with granisetron and dexamethasone, Granisetron and dexamethasone - Hepatocellular Carcinoma | Phase 3 | Unknown | Guangxi Medical University | 300 | 2024-07-01 | 2024-01-23 |
| Reducing Inflammatory Syndrome in Surgery - Colorectal (RISIS-CR) Trial Alpha-ketoglutarate, Placebo, Standard care - Colorectal Cancer | Phase 3 | Unknown | National University Hospital, Singapore | 80 | 2024-05-09 | 2024-10-17 |
| Proactive Management of Endoperitoneal Spread in Colonic Cancer Standard surgical treatment, Proactive management, Standard adjuvant systemic chemotherapy - Colon Cancer, Intraperitoneal Rectal Cancer | Phase 3 | Unknown | University of Roma La Sapienza | 140 | 2024-03-01 | 2023-05-06 |
| Adjuvant Tislelizumab Plus Lenvatinib for Patients at High-risk of HCC Recurrence After Curative Resection or Ablation Adjuvant tislelizumab plus lenvatinib, Adjuvant tislelizumab - Hepatocellular Carcinoma, Recurrence | Phase 3 | Unknown | Guangxi Medical University | 200 | 2024-02-15 | 2024-01-23 |
| Postoperative Immune Maintenance Therapy for Esophageal Squamous Cell Carcinoma After Radical Resection sintilimab - Esophageal Squamous Cell Carcinoma Thoracic Stage II, Esophageal Squamous Cell Carcinoma Thoracic Stage III | Phase 3 | Unknown | Fujian Medical University Union Hospital | 400 | 2024-01-10 | 2023-12-08 |
| Clinical Study of Dexmedetomidine Administered Intranasally to Relieve Perioperative Anxiety and Depression in Patients With Colorectal Tumors Dexmedetomidine administered intranasally - Colorectal Cancer | Phase 3 | Unknown | First Affiliated Hospital of Chongqing Medical University | 126 | 2023-12-01 | 2024-04-09 |
| Aspiration of Duodenopancreatic Juice After Secretin Stimulation vs Endoscopic Aspiration for Molecular Analysis of Intraductal Papillary Mucinous Intraductal Neoplasia. Secretin, Endoscopic aspiration, Endoscopic ultrasound-guided fine needle aspiration - Intraductal Papillary Mucinous Neoplasm of Pancreas | Phase 3 | Unknown | Fundacion Clinic per a la Recerca Biomédica | 140 | 2023-09-13 | 2023-09-18 |
| Sulfasalazine in Patients With Metastatic Colorectal Cancer Sulfasalazine - Metastatic Colorectal Cancer | Phase 3 | Unknown | Tanta University | 50 | 2023-09-01 | 2023-11-18 |
| Neoadjuvant Chemotherapy With PD-1 Inhibitors Combined With SIB-IMRT in the Treatment of Locally Advanced Rectal Cancer Tislelizumab, Capecitabine, Oxaliplatin - Rectal Neoplasms | Phase 3 | Unknown | Yong Zhang,MD | 48 | 2023-09-01 | 2023-10-11 |
| Effects of Immunonutrition on the Improvement of Postoperative Adjuvant Chemotherapy Related Adverse Reactions in Patients With Gastrointestinal Tumors Immunonutrition （Su yusu), fluorouracil based chemotherapy regimens - Gastrointestinal Tumors, Immunonutrition | Phase 3 | Unknown | China Medical University, China | 324 | 2023-07-24 | 2023-10-16 |
| Cetuximab+mFOLFOX6 VS. mFOLFOX6 Alone in RAS/BRAF Wild Type Patients With High-Risk Resectable CRLM mFOLFOX6 + Cetuximab, mFOLFOX 6 - Colorectal Cancer, Liver Metastases | Phase 3 | Unknown | Fudan University | 250 | 2023-07-15 | 2023-07-17 |
| Electromagnetic Fields Versus Placebo For Child-Pugh A and B Patients With Advanced Hepatocellular Carcinoma TheraBionic Device, Placebo Device, Quality of Life Assessment - Hepatocellular Carcinoma | Phase 2 / Phase 3 | Unknown | THERABIONIC INC. | 166 | 2023-07-01 | 2023-06-28 |
| HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC HAIC, Zoledronic acid - Hepatocellular Carcinoma | Phase 3 | Unknown | Sun Yat-sen University | 264 | 2023-05-10 | 2023-05-19 |
| Glucose Control Through a Bihormonal Artificial Pancreas in Patients After Total Pancreatectomy Bihormonal artificial pancreas (BIHAP) / closed loop - Pancreatic Neoplasms, Type 3c Diabetes | Phase 3 | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 40 | 2023-04-25 | 2024-04-04 |
| Nitazoxanide in Patients With Metastatic Colorectal Cancer Nitazoxanide - Metastatic Colorectal Cancer | Phase 3 | Unknown | Tanta University | 60 | 2023-03-01 | 2023-09-22 |
| PD-1 Antibody Combined With mXELIRI Versus mXELIRI in the Second-line Setting for ESCC PD-1 Inhibitors, Irinotecan, Capecitabine tablets - Esophageal Squamous Cell Carcinoma Abdominal Stage 0 | Phase 3 | Unknown | Sun Yat-sen University | 380 | 2023-02-17 | 2024-01-23 |
| Effect of Silymarin in Metastatic Colorectal Cancer Patients Silymarin - Metastatic Colorectal Cancer | Phase 3 | Unknown | Tanta University | 64 | 2022-12-31 | 2023-12-22 |
| Icaritin Soft Capsule Versus Huachansu Tablet in the First-line Treatment of Unresectable Hepatocellular Carcinoma With Poor Conditions and Biomarker Enrichment (Biomarker Enrichment Study of Poor Prognosis HCC Patients, BESTPOP) Icaritin, Huachansu - Hepatocellular Carcinoma | Phase 3 | Unknown | Beijing Shenogen Biomedical Co., Ltd | 261 | 2022-12-12 | 2024-08-07 |
| the Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma Rulonilimab+Lenvatinib, Rulonilimab placebo +Lenvatinib - Hepatocellular Carcinoma | Phase 2 / Phase 3 | Unknown | Shandong New Time Pharmaceutical Co., LTD | 576 | 2022-11-11 | 2023-03-10 |
Showing 20 of 474. Sign in to see all of them.
Colorectal Neoplasms (117) · Carcinoma, Hepatocellular (98) · Stomach Neoplasms (82) · Rectal Neoplasms (65) · Colonic Neoplasms (54) · Esophageal Neoplasms (40) · Pancreatic Neoplasms (33) · Liver Neoplasms (19) · Esophageal Squamous Cell Carcinoma (18) · Neoplasm Metastasis (18) · Neoplasms (7) · Cholangiocarcinoma (6) · Recurrence (6) · Adenocarcinoma Of Esophagus (5) · Anastomotic Leak (5)
Digestive System Diseases (474) · Neoplasms by Site (472) · Neoplasms (467) · Gastrointestinal Diseases (325) · Gastrointestinal Neoplasms (321) · Intestinal Diseases (190) · Intestinal Neoplasms (190) · Rectal Diseases (159) · Colonic Diseases (151) · Neoplasms by Histologic Type (137) · Neoplasms, Glandular and Epithelial (131) · Carcinoma (126) · Liver Diseases (105) · Adenocarcinoma (104)
Oxaliplatin (60) · Fluorouracil (57) · Capecitabine (54) · Leucovorin (41) · Radiotherapy (23) · Drug Therapy (20) · Gemcitabine (20) · Irinotecan (20) · Cisplatin (19) · Paclitaxel (17) · Folfox protocol (15) · Sorafenib (14) · XELOX (14) · Chemotherapy, Adjuvant (13) · Cetuximab (12)
Sun Yat-sen University (46) · Fudan University (36) · Guangxi Medical University (12) · Chinese Academy of Medical Sciences (9) · Sixth Affiliated Hospital, Sun Yat-sen University (9) · Tianjin Medical University Cancer Institute and Hospital (9) · Shanghai Zhongshan Hospital (8) · Chinese University of Hong Kong (7) · RenJi Hospital (7) · The First Affiliated Hospital of Henan University of Science and Technology (7) · GERCOR - Multidisciplinary Oncology Cooperative Group (6) · Samsung Medical Center (6) · West China Hospital (6) · Blokhin's Russian Cancer Research Center (5) · National Taiwan University Hospital (5)
China (248) · South Korea (25) · France (20) · Italy (19) · Netherlands (16) · United Kingdom (16) · United States (15) · Egypt (11) · Germany (11) · Taiwan (11) · Spain (10) · India (9) · Japan (9) · Canada (6) · Belgium (5)
Ming Shi, MD (5) · Jia Fan, MD (4) · Shegan Gao, Doctor (4) · Tanyou Shan, Master (4) · Xiaozhi Yuan, Master (4) · Aimery de Gramont, MD (3) · Dan Wang, Master (3) · Enders K.W. Ng, MD (3) · Gao-Jun Teng, MD (3) · Guoqiang Kong, Master (3) · Jiachun Sun, Doctor (3) · Jing Ren, Master (3) · Lawrence A. Romel, MS (3) · Ruina Yang, Master (3) · Ruinuo Jia, Master (3)
PMID 12049862, PMID 11981766, PMID 12091661, PMID 12540794, PMID 20718753, PMID 22895629, PMID 23148692, PMID 23599758, PMID 24224128, PMID 24371038, PMID 25077927, PMID 26805559, PMID 27223606, PMID 27266524, PMID 27742014, PMID 36306483, PMID 41252656, PMID 41379261, PMID 10207464, PMID 10215657, PMID 10400410, PMID 10402169, PMID 10655437, PMID 10671580, PMID 10751477, PMID 10789750, PMID 10932224, PMID 10987278, PMID 11050095, PMID 11202797, PMID 11208818, PMID 11413430, PMID 11419162, PMID 11509137, PMID 11602056, PMID 11727523, PMID 11813623, PMID 11895791, PMID 11961194, PMID 12047964, PMID 12508355, PMID 12522441, PMID 12594571, PMID 12616414, PMID 12623635, PMID 12697873, PMID 12727116, PMID 12893895, PMID 14673047, PMID 15273542
2015 (2), 2008 (1), 2009 (1), 2014 (1), 2016 (1), 2018 (1), 2019 (1), R44CA256984 (1), U10CA031946 (1)