Digestive System Neoplasms: Clinical Trials

1,392 trials for Digestive System Neoplasms, newest first

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1392 unknown. 1392 Phase 2, 204 Phase 1, 99 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 21392Unknown 1392
Phase 1204Unknown 204
Phase 399Unknown 99

Follow Digestive System Neoplasms: new trials by email Literature Review of Digestive System Neoplasms trials Research Report on Digestive System Neoplasms

Trials (filtered) newest first · largest first

All 1,392 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study
Node-Sparing Short-Course Radiotherapy Combined with CAPOX and Sintilimab, CAPOX Chemotherapy - Microsatellite Stable (MSS) Colon Cancer, Locally Advanced Colon Cancer
Phase 2UnknownSir Run Run Shaw Hospital1402024-10-012024-09-19
BTLA Inhibitor (JS004) Combined with Toripalimab and Chemotherapy in the Perioperative Treatment of Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
BTLA inhibitor (JS004), Toripalimab, Paclitaxel, Cisplatin - Esophageal Squamous Cell Carcinoma
Phase 2UnknownHenan Provincial People's Hospital202024-09-302024-09-19
A Study of Camrelizumab Plus Apatinib as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Radical Resection or Ablation
Camrelizumab, Apatinib - Hepatocellular Carcinoma
Phase 2UnknownZhujiang Hospital382024-08-262024-08-09
Modified FOLFOXIRI Plus Target Therapy as a First Line Treatment for Advanced Colorectal Cancer a Prospective Phase Two Study
FOLFOXIRI Protocol - Neoplasm Malignant, Colon Cancer Stage 4
Phase 2UnknownAl-Azhar University602024-08-172024-08-28
Exploratory Study of Irinotecan Liposomes in Maintenance Therapy of Metastatic Colorectal Cancer
Irinotecan Liposome, Bevacizumab - Metastatic Colorectal Cancer
Phase 1 / Phase 2UnknownWest China Hospital202024-08-092024-08-09
A Study on the Combination of Sintilimab, Ramucirumab and Chemotherapy for First-line Treatment of Gastric Cancer With Liver Metastasis
Sintilimab, Ramucirumab, SOX/XELOX - Stomach Neoplasms
Phase 2UnknownThe First Affiliated Hospital with Nanjing Medical University392024-08-012024-08-28
Cryoablation Combined With PD-1 Antibody and Bevacizumab for Hepatocellular Carcinoma
Cryoablation, PD-1 antibody and bevacizumab - Carcinoma, Hepatocellular
Phase 2UnknownShanghai Zhongshan Hospital362024-07-312024-07-31
Prospective Phase II Study on Continuous Circumferential Reinforcement of Laparoscopic Rectal Anastomosis to Prevent Complications
Continuous Circumferential Reinforcement of the Anastomotic - Colorectal Cancer, Anastomotic Leakage
Phase 2UnknownZHI-ZHONG PAN2082024-07-202024-07-11
HAIC Combined With TQB2450 and Anlotinib in Second-line Treatment of Advanced Hepatocellular Carcinoma
HAIC(Mitoxantrone+Raltitrexed)、anlotinib、TQB2450 - Hepatocellular Carcinoma
Phase 2UnknownFudan University422024-07-202024-06-26
MRD-Guided Consolidation Therapy Following Definitive Radiotherapy in Esophageal Cancer
PD-1 monoclonal antibody consolidation therapy - Esophageal Cancer
Phase 2UnknownCancer Institute and Hospital, Chinese Academy of Medical Sciences1022024-07-162024-08-06
Adebrelimab in Combination With Apatinib and Chemotherapy/Chemoradiotherapy in Immuno-experienced Second-line ESCC.
Adebrelimab, Apatinib, Investigator chosen chemotherapy (ICC) - Esophageal Cancer
Phase 2UnknownThe First Affiliated Hospital of Henan University of Science and Technology542024-07-152024-06-18
Trilaciclib Combined With Concurrent Chemoradiotherapy and Immunotherapy in the Treatment of Esophageal Cancer
Trilaciclib Injection [Cosela], Placebo - Esophageal Cancer
Phase 2UnknownThe First Affiliated Hospital with Nanjing Medical University602024-07-092024-08-26
Safety and Efficacy of Autologous Tumor-infiltrating Lymphocytes Therapy in Patients With Hepatocellular Carcinoma
Autologous Tumor-infiltrating Lymphocytes - Hepatocellular Carcinoma
Phase 1 / Phase 2UnknownBeijing 302 Hospital202024-07-012024-08-13
First-Line Treatment Induced With mFOLFOX6 and HLX04 Regimen, Following Combined With Serplulimab in MSS Initially Unresectable Metastatic Colorectal Cancer
mfolfox6 and hlx04 regimen and Serplulimab, mfolfox6 and hlx04 regimen - Efficacy, Self, Safety Issues
Phase 2UnknownSir Run Run Shaw Hospital722024-07-012024-07-09
HAIC Combined With Adebrelimab Plus Apatinib as the First-line Treatment for HCC in BCLC Stage C: An Open-label, Single-arm, Phase II Study
Hepatic arterial infusion chemotherapy(HAIC) combined with adebrelimab plus apatinib - Hepatocellular Carcinoma
Phase 2UnknownSun Yat-sen University332024-06-192024-07-01
Adebrelimab in Combination With NALIRIFOX in Locally Advanced Pancreatic Cancer
Adebrelimab, Oxaliplatin 100 MG, Irinotecan liposome - Pancreatic Cancer
Phase 2UnknownFudan University872024-06-052024-08-09
Liposomal Irinotecan Plus Bevacizumab in Irinotecan-refractory Metastatic Colorectal Cancer
Liposomal irinotecan, Bevacizumab - Colorectal Cancer
Phase 1 / Phase 2UnknownSun Yat-sen University742024-06-052024-05-30
Multimodal Rehabilitation on Gastric Adenocarcinoma Patients Following Radical D2 Gastrectomy
Standard SOX/XELOX adjuvant chemotherapy plus multimodal rehabilitation - Gastric Cancer
Phase 2UnknownZhejiang Cancer Hospital1382024-06-012024-05-17
Chemotherapy Plus Bevacizumab and Anti-PD-1 Followed by Induction Therapy of Chemotherapy Plus Bevacizumab
mFOLFOX6 regimen + bevacizumab + PD-1 monoclonal antibody - Metastatic Colorectal Cancer, MSS
Phase 2UnknownZhangfa Song362024-06-012024-05-16
Phase II Study of Liposomal Irinotecan for Advanced Refractory Gastric Cancer
Liposomal Irinotecan Hydrochloride - Gastric Cancer
Phase 2UnknownZhejiang Cancer Hospital502024-05-272024-05-31

Showing 20 of 1392. Sign in to see all of them.

Narrower conditions

Colorectal Neoplasms (324)  ·  Stomach Neoplasms (285)  ·  Carcinoma, Hepatocellular (241)  ·  Pancreatic Neoplasms (163)  ·  Rectal Neoplasms (123)  ·  Esophageal Neoplasms (121)  ·  Esophageal Squamous Cell Carcinoma (102)  ·  Colonic Neoplasms (90)  ·  Liver Neoplasms (53)  ·  Neoplasm Metastasis (48)  ·  Biliary Tract Neoplasms (40)  ·  Neoplasms (31)  ·  Breast Neoplasms (25)  ·  Gastrointestinal Neoplasms (21)  ·  Carcinoma, Non-Small-Cell Lung (20)

Broader conditions

Digestive System Diseases (1390)  ·  Neoplasms by Site (1383)  ·  Neoplasms (1361)  ·  Gastrointestinal Diseases (940)  ·  Gastrointestinal Neoplasms (922)  ·  Intestinal Diseases (480)  ·  Intestinal Neoplasms (475)  ·  Rectal Diseases (423)  ·  Neoplasms by Histologic Type (410)  ·  Neoplasms, Glandular and Epithelial (390)  ·  Colonic Diseases (387)  ·  Carcinoma (370)  ·  Stomach Diseases (286)  ·  Liver Diseases (273)

Interventions

Oxaliplatin (159)  ·  Capecitabine (124)  ·  Fluorouracil (111)  ·  Irinotecan (89)  ·  Leucovorin (72)  ·  S 1 (combination) (70)  ·  Cisplatin (69)  ·  apatinib (69)  ·  Paclitaxel (66)  ·  Bevacizumab (64)  ·  sintilimab (62)  ·  Gemcitabine (60)  ·  camrelizumab (56)  ·  Radiotherapy (51)  ·  Cetuximab (49)

Sponsors

Fudan University (73)  ·  Sun Yat-sen University (63)  ·  Tianjin Medical University Cancer Institute and Hospital (38)  ·  Chinese Academy of Medical Sciences (26)  ·  Shanghai Zhongshan Hospital (25)  ·  Zhejiang Cancer Hospital (24)  ·  Peking University (19)  ·  National Cancer Center, Korea (18)  ·  Chinese PLA General Hospital (17)  ·  Second Affiliated Hospital, Zhejiang University, School of Medicine (17)  ·  Cancer Institute and Hospital, Chinese Academy of Medical Sciences (16)  ·  GERCOR - Multidisciplinary Oncology Cooperative Group (15)  ·  Samsung Medical Center (15)  ·  The First Affiliated Hospital of Zhengzhou University (15)  ·  The First Affiliated Hospital with Nanjing Medical University (15)

Countries

China (743)  ·  South Korea (98)  ·  United States (87)  ·  Taiwan (35)  ·  France (34)  ·  United Kingdom (32)  ·  Japan (29)  ·  Netherlands (27)  ·  Germany (26)  ·  Italy (26)  ·  Spain (19)  ·  Singapore (15)  ·  Canada (13)  ·  Brazil (12)  ·  Australia (11)

Top investigators

Feng Wang (5)  ·  Lin Shen, MD (5)  ·  Lin Shen, Professor (5)  ·  Wei Peng Yong, MRCP, MB ChB (5)  ·  Christophe Louvet, MD, PhD (3)  ·  Fuxiang Zhou, M.D. (3)  ·  Gang Jin, Doctor (3)  ·  Gao-Jun Teng, MD (3)  ·  Haitao Zhao, MD (3)  ·  Hui-Ju Ch'ang, M.D. (3)  ·  Jian Zhou (3)  ·  Jingdong Zhang (3)  ·  Kun Huei Yeh, Ph.D. (3)  ·  Lin Yang, Ph.D. (3)  ·  Ruihua Xu, MD, PhD (3)

Results publications

PMID 30642373, PMID 35623069, PMID 12049862, PMID 12540794, PMID 15273542, PMID 20516446, PMID 23547081, PMID 25447852, PMID 25514302, PMID 26313683, PMID 26755520, PMID 26884585, PMID 27480145, PMID 28434648, PMID 30348638, PMID 32306237, PMID 34725214, PMID 35219300, PMID 36657089, PMID 37981041, PMID 38421211, PMID 39863139, PMID 41379261, PMID 10089184, PMID 10091726, PMID 10400410, PMID 10615932, PMID 10744089, PMID 11091234, PMID 11223832, PMID 11247898, PMID 11248153, PMID 11251976, PMID 11289756, PMID 11413430, PMID 11419162, PMID 11574279, PMID 11712875, PMID 11754382, PMID 11813623, PMID 11896099, PMID 11981766, PMID 12091661, PMID 12187070, PMID 12196368, PMID 12378346, PMID 1334988, PMID 14525967, PMID 14578723, PMID 14759776

NIH funding

2016 (5), 2018 (5), P30CA015083 (4), 2009 (3), 2015 (3), 2017 (3), 2019 (3), 2008 (2), 2005 (1), 2014 (1), M01RR000096 (1), P20CA252732 (1), P30CA168524 (1), R44CA256984 (1), U10CA031946 (1)