621 unknown. 621 Phase 1, 298 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 621 | Unknown 621 |
| Phase 2 | 298 | Unknown 298 |
Follow Digestive System Diseases: new trials by email Literature Review of Digestive System Diseases trials Research Report on Digestive System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Single and Multiple Ascending Doses of H021 in Healthy Participants H021, H021 Placebo - Ulcerative Colitis | Phase 1 | Unknown | Jiangsu Carephar Pharmaceutical Co., Ltd. | 64 | 2024-09-17 | 2024-10-04 |
| Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics Trimebutine, Lactobacillus rhamnosus, Placebo - Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders | Phase 1 / Phase 2 | Unknown | Universidad de Colima | 82 | 2024-09-01 | 2024-08-16 |
| Beta-Hydroxybutyrate Feasibility Treating IBD Feasibility of beta-hydroxybutyrate supplementation to reduce inflammation in patients with Crohn's - Crohn's Disease, Inflammatory Bowel Diseases | Phase 1 / Phase 2 | Unknown | University of Texas at Austin | 20 | 2024-08-28 | 2024-09-19 |
| Exploratory Study of Irinotecan Liposomes in Maintenance Therapy of Metastatic Colorectal Cancer Irinotecan Liposome, Bevacizumab - Metastatic Colorectal Cancer | Phase 1 / Phase 2 | Unknown | West China Hospital | 20 | 2024-08-09 | 2024-08-09 |
| Effects of Exosome Adminstration in Preventing Early Leakage in Rectal Cancer Patients Undergoing Low Anterior Resection Mesenchymal Stem Cells Derived Exosomes, Placebo - Rectal Cancer | Phase 1 | Unknown | Tehran University of Medical Sciences | 20 | 2024-08-01 | 2024-08-05 |
| A Study to Compare and Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of UI059 and UIC202201 UI059, UIC202201 - Gastro-Intestinal Disorder | Phase 1 | Unknown | Korea United Pharm. Inc. | 66 | 2024-07-03 | 2024-05-01 |
| Safety and Efficacy of Autologous Tumor-infiltrating Lymphocytes Therapy in Patients With Hepatocellular Carcinoma Autologous Tumor-infiltrating Lymphocytes - Hepatocellular Carcinoma | Phase 1 / Phase 2 | Unknown | Beijing 302 Hospital | 20 | 2024-07-01 | 2024-08-13 |
| Safety of DNP007 in Healthy Subjects DNP007 - Liver Transplant Rejection, Liver Transplant; Complications | Phase 1 | Unknown | Seoul National University Hospital | 12 | 2024-06-10 | 2024-06-18 |
| Liposomal Irinotecan Plus Bevacizumab in Irinotecan-refractory Metastatic Colorectal Cancer Liposomal irinotecan, Bevacizumab - Colorectal Cancer | Phase 1 / Phase 2 | Unknown | Sun Yat-sen University | 74 | 2024-06-05 | 2024-05-30 |
| Clinical Study Evaluating the Safety and Efficacy of Esomeprazole in Treatment of Non-alcoholic Steatohepatitis Esomeprazole, Placebo - Fatty Liver Disease, Steatohepatitis, Nonalcoholic | Phase 1 / Phase 2 | Unknown | Sadat City University | 46 | 2024-06-01 | 2024-05-22 |
| A Clinical Study to Evaluate the Efficacy of TQA3038 Injection in Patients With Chronic Hepatitis B TQA3038 injection/placebo, Nucleotide drugs Control group - Hepatitis B, Chronic | Phase 1 / Phase 2 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 162 | 2024-06-01 | 2024-06-11 |
| Multimodal Imaging in Rectal Cancer & Pancreatic Cancer [111In]In-DOTA-ANTI-CEA antibody injection, SPECT/CT scan, Resection surgery - Rectal Cancer, Pancreatic Cancer | Phase 1 / Phase 2 | Unknown | Radboud University Medical Center | 20 | 2024-05-02 | 2024-05-02 |
| Effect of 4 Weeks of Oral D. Piger on Safety, Pharmacokinetics and Ethanol Metabolism in Overweight Individuals (2023) D piger, Placebo - Obesity, Metabolic Syndrome | Phase 1 | Unknown | Max Nieuwdorp | 20 | 2024-05-01 | 2024-07-16 |
| Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial for First-line Treatment of Hepatocellular Carcinoma γδ T cells, Targeted drugs, PD-1 monoclonal antibody - Hepatocellular Carcinoma | Phase 1 | Unknown | Beijing 302 Hospital | 18 | 2024-04-26 | 2024-04-15 |
| Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula Mesenchymal Stem Cells (MSCs) - Anal Fistula, Complex Perianal Fistulas | Phase 1 | Unknown | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | 8 | 2024-04-08 | 2024-06-12 |
| A Clinical Study of T3011 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer T3011 hepatic artery infusion, toripalimab, regorafenib - Colorectal Cancer Metastatic | Phase 1 | Unknown | China Medical University, China | 8 | 2024-04-02 | 2024-02-29 |
| Fecal Transplantation in Patients Colonic Diverticulitis Fecal Microbiome, Placebo - Diverticulitis, Colonic, Colon Inflamed | Phase 1 | Unknown | Odense University Hospital | 40 | 2024-04-01 | 2024-04-05 |
| Food Effect on the Bioavailability of 4-MUST, Tablets, 128 mg 4-MUST, 2 tablets, fasted, 4-MUST, 2 tablets, after meals - Cholecystitis | Phase 1 | Unknown | Valenta Pharm JSC | 24 | 2024-03-19 | 2024-04-02 |
| Study of WM-A1-3389 in Participants With Advanced or Metastatic Solid Tumors and Non-Small Cell Lung Cancer (MK-3475-E90/KEYNOTE-E90) WM-A1-3389, Pembrolizumab - Advanced Solid Tumor, Metastatic Solid Tumor | Phase 1 | Unknown | Wellmarker Bio | 54 | 2024-03-14 | 2024-03-12 |
| Dose Escalation and Expansion Clinical Trial of Irinotecan Liposome Combined With Oxaliplatin and 5-FU/LV Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer Irinotecan Liposome, Oxaliplatin, 5-FU - Metastatic Colorectal Cancer | Phase 1 | Unknown | Shanghai Zhongshan Hospital | 78 | 2024-03-11 | 2024-03-19 |
Showing 20 of 621. Sign in to see all of them.
Colorectal Neoplasms (113) · Carcinoma, Hepatocellular (109) · Pancreatic Neoplasms (101) · Stomach Neoplasms (92) · Esophageal Neoplasms (44) · Colonic Neoplasms (37) · Breast Neoplasms (36) · Rectal Neoplasms (28) · Carcinoma, Non-Small-Cell Lung (26) · Liver Neoplasms (26) · Ovarian Neoplasms (25) · Liver Cirrhosis (23) · Lung Neoplasms (21) · Neoplasm Metastasis (21) · Neoplasms (20)
Neoplasms by Site (435) · Digestive System Neoplasms (433) · Neoplasms (425) · Gastrointestinal Diseases (342) · Gastrointestinal Neoplasms (252) · Intestinal Diseases (207) · Liver Diseases (207) · Neoplasms by Histologic Type (178) · Neoplasms, Glandular and Epithelial (165) · Colonic Diseases (159) · Intestinal Neoplasms (156) · Carcinoma (150) · Rectal Diseases (138) · Adenocarcinoma (122)
Gemcitabine (26) · Capecitabine (21) · Oxaliplatin (20) · Paclitaxel (17) · Fluorouracil (16) · pembrolizumab (14) · Nivolumab (12) · camrelizumab (12) · Radiotherapy (11) · apatinib (11) · 130-nm albumin-bound paclitaxel (10) · Cyclophosphamide (10) · Injections (10) · Irinotecan (10) · toripalimab (10)
Beijing 302 Hospital (10) · Fudan University (8) · Shanghai Zhongshan Hospital (8) · Sun Yat-sen University (8) · Chinese PLA General Hospital (7) · National Taiwan University Hospital (7) · Chinese Academy of Medical Sciences (6) · Peking Union Medical College Hospital (6) · West China Hospital (6) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (5) · National University Hospital, Singapore (5) · Third Affiliated Hospital, Sun Yat-Sen University (5) · Zhejiang Cancer Hospital (5) · Betta Pharmaceuticals Co., Ltd. (4) · China Medical University, China (4)
China (270) · United States (84) · South Korea (41) · Japan (20) · United Kingdom (19) · Taiwan (18) · Netherlands (13) · Australia (12) · France (11) · Germany (10) · Singapore (9) · Egypt (8) · Switzerland (8) · Canada (7) · Israel (7)
Daiming Fan (3) · Lin Yang, Ph.D. (3) · Fu-Sheng Wang, professor (2) · Gang Jin, Doctor (2) · Hui-Ju Ch'ang, M.D. (2) · Jin Li, MD (2) · Junqi Niu, PHD (2) · Lee S. Rosen, MD (2) · Lin Shen (2) · Lin Shen, Doctor (2) · Lin Shen, MD (2) · Mamun A Mahtab, MSc MD FACG (2) · Mitsukazu Gotoh, MD & PhD (2) · Rania A El-Farrash, MD (2)
PMID 15530127, PMID 1559306, PMID 15623621, PMID 15868910, PMID 16564913, PMID 16951235, PMID 17560413, PMID 17903050, PMID 19192962, PMID 19455046, PMID 19459850, PMID 19638109, PMID 19731245, PMID 20094812, PMID 20149262, PMID 20371346, PMID 20393336, PMID 20874827, PMID 20959411, PMID 21277098, PMID 21926976, PMID 22245781, PMID 22443802, PMID 22461641, PMID 22589701, PMID 22818551, PMID 2292168, PMID 23134470, PMID 23292233, PMID 23473061, PMID 23648372, PMID 23658246, PMID 23822453, PMID 23840001, PMID 24164605, PMID 24351336, PMID 24360117, PMID 24497570, PMID 24641416, PMID 24667978, PMID 24668644, PMID 24708624, PMID 24856171, PMID 24876849, PMID 25104129, PMID 25151979, PMID 25213161, PMID 25421252, PMID 25467588, PMID 25586952
2015 (4), 2009 (3), 2016 (2), 2017 (2), 2018 (2), 2019 (2), 2023 (2), 2014 (1), M01RR000051 (1), P30CA015083 (1)