41 completed. 41 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 41 | Completed 41 |
Follow Diabetic Nephropathies: new trials by email Literature Review of Diabetic Nephropathies trials Research Report on Diabetic Nephropathies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Perfenidone in Type 2 Diabetic Patients With Diabetic Neuropathy Pirfenidone, Placebo - Diabetic Nephropathies, Type 2 Diabetes | Phase 4 | Completed | Sidrah Lodhi | 60 | 2024-03-10 | 2025-03-11 |
| DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study Salt-Diet and/or Ertugliflozin, Ertugliflozin 15 mg - Diabetes Mellitus, Diabetic Kidney Disease | Phase 4 | Completed | Amsterdam UMC, location VUmc | 41 | 2023-07-03 | 2026-04-15 |
| Basal Plus GLP1-ra on Glycemic Variability in CKD Dulaglutide, Insulin Degludec, Continuous glucose monitor - Diabetes Mellitus, Diabetic Kidney Disease | Phase 4 | Completed | Elaine Chow | 95 | 2022-01-28 | 2024-12-03 |
| Study of Roxadustat's Effect on Anemia in Patients With Diabetic Kidney Disease Roxadustat - Diabetic Kidney Disease, Anemia | Phase 4 | Completed | Second Xiangya Hospital of Central South University | 124 | 2021-11-02 | 2026-01-26 |
| Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study. Ertugliflozin 15 mg - Type 2 Diabetes Mellitus, Diabetic Kidney Disease | Phase 4 | Completed | Amsterdam UMC, location VUmc | 40 | 2020-12-10 | 2023-05-01 |
| Renohemodynamic Effects of Combined empagliflOzin and LosARtan Empagliflozin 10 MG, Losartan 50Mg Tab, Placebo - Diabetes Mellitus, Type 2, Diabetic Kidney Disease | Phase 4 | Completed | Amsterdam UMC, location VUmc | 24 | 2020-11-04 | 2021-10-08 |
| Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 Diabetes sodium bicarbonate - Type 1 Diabetes, Diabetic Nephropathy | Phase 4 | Completed | University of Colorado, Denver | 45 | 2017-01-01 | 2026-06-17 |
| CPAP Effect on Albuminuria in Patients With Diabetic Nephropathy and Obstructive Sleep Apnea Continuous positive airway pressure, Pharmacological treatment, Diet - Diabetic Nephropathy, Sleep Apnea | Phase 4 | Completed | Hospital Universitario La Paz | 180 | 2016-06-01 | 2021-05-11 |
| Effect of Exenatide on 24h-UAER in Patients With Diabetic Nephropathy Exenatide, Lispro - Diabetic Nephropathies | Phase 4 | Completed | Nanfang Hospital, Southern Medical University | 92 | 2016-04-08 | 2020-03-09 |
| Renoprotective Effects of Dapagliflozin in Type 2 Diabetes Dapagliflozin 10mg QD, Gliclazide 30mg QD - Diabetes Mellitus, Type 2, Diabetic Nephropathies | Phase 4 | Completed | M.H.H. Kramer | 44 | 2016-02-01 | 2020-07-07 |
| Lipo-prostaglandin E1 Improves Renal Hypoxia Evaluated by BOLD-MRI in Patients With Diabetic Nephropathy Lipo-PGE1 - Diabetic Nephropathy | Phase 4 | Completed | West China Hospital | 21 | 2015-12-01 | 2016-12-29 |
| Effects of Dapagliflozin Treatment on Urinary Proteomic Patterns in Patients With Type 2 Diabetes Dapagliflozine 10 mg once daily tablet treatment, Placebo identical once daily tablet treatment - Type 2 Diabetes, Diabetic Nephropathy | Phase 4 | Completed | Peter Rossing | 40 | 2015-08-01 | 2018-09-10 |
| Add-on Pentoxifylline to Losartan Versus Increasing Dose of Losartan on NT-PRO BNP in Type 2 Diabetics With Nephropathy Pentoxifylline, Losartan - Diabetic Nephropathies | Phase 4 | Completed | Tehran University of Medical Sciences | 59 | 2015-04-01 | 2016-12-30 |
| Antiproteinuric Effects of Liraglutide Treatment Liraglutide, placebo - Diabetic Kidney Disease | Phase 4 | Completed | Steno Diabetes Center Copenhagen | 32 | 2015-04-01 | 2016-08-10 |
| Microalbuminuria and Allopurinol in Type 1 Diabetes Allopurinol, Placebo - Type 1 Diabetes, Diabetic Nephropathy | Phase 4 | Completed | Peter Rossing | 30 | 2014-09-01 | 2018-09-10 |
| Effect of LIXIsenatide on the Renal System Lixisenatide, Insulin glulisine - Diabetic Kidney Disease, Diabetic Nephropathy | Phase 4 | Completed | Amsterdam UMC, location VUmc | 40 | 2014-09-01 | 2016-04-29 |
| Renal Effects of DPP-4 Inhibitor Linagliptin in Type 2 Diabetes Linagliptin 5 mg QD (N=24), Glimepiride 1 mg QD (N=24) - Type 2 Diabetes | Phase 4 | Completed | Amsterdam UMC, location VUmc | 48 | 2014-03-01 | 2016-05-17 |
| Effect of Sarpogrelate On the Nephropathy in Type 2 Diabetes (SONATA Study) Anplag(Sarpogrelate), Placebo - Diabetic Nephropathy | Phase 4 | Completed | Yuhan Corporation | 151 | 2013-02-01 | 2021-04-23 |
| The Effect of Uric Acid Lowering in Type 1 Diabetes Febuxostat - Type 1 Diabetes Mellitus | Phase 4 | Completed | University Health Network, Toronto | 73 | 2012-12-18 | 2018-01-16 |
| Effects of Liraglutide on Kidney Function in Type 2 Diabetic Patients Liraglutide, Placebo-liraglutide - Type 2 Diabetes Mellitus | Phase 4 | Completed | University of Aarhus | 11 | 2012-12-01 | 2014-02-28 |
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Diabetes Mellitus, Type 2 (10) · Diabetes Mellitus (9) · Hypertension (4) · Kidney Diseases (4) · Albuminuria (3) · Diabetes Mellitus, Type 1 (3) · Proteinuria (3) · Cardiovascular Diseases (2) · Diabetes Complications (2) · Kidney Failure, Chronic (2) · Renal Insufficiency (2) · Renal Insufficiency, Chronic (2) · Anemia (1) · Autoimmune Lymphoproliferative Syndrome, Type IA (1)
Endocrine System Diseases (41) · Female Urogenital Diseases (41) · Female Urogenital Diseases and Pregnancy Complications (41) · Male Urogenital Diseases (41) · Urogenital Diseases (41) · Urologic Diseases (41) · Diabetes Complications (39) · Kidney Diseases (37) · Diabetes Mellitus (32) · Glucose Metabolism Disorders (20) · Metabolic Diseases (20) · Nutritional and Metabolic Diseases (20) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (6) · Urination Disorders (6)
Losartan (4) · Ramipril (3) · Telmisartan (3) · Cilostazol (2) · Hydrochlorothiazide (2) · Liraglutide (2) · Lisinopril (2) · Valsartan (2) · ertugliflozin (2) · Adrenocorticotropic Hormone (1) · Allopurinol (1) · Alprostadil (1) · Amlodipine (1) · Aspirin (1) · Atenolol (1)
Amsterdam UMC, location VUmc (5) · Boehringer Ingelheim (3) · Peter Rossing (3) · Steno Diabetes Center Copenhagen (3) · Gulhane School of Medicine (2) · Assistance Publique - Hôpitaux de Paris (1) · Baker Heart and Diabetes Institute (1) · Chinese University of Hong Kong (1) · Elaine Chow (1) · Fresenius Kabi (1) · Hospital Universitario La Paz (1) · M.H.H. Kramer (1) · Nanfang Hospital, Southern Medical University (1) · Novartis (1) · Otsuka Beijing Research Institute (1)
Denmark (9) · Netherlands (7) · China (4) · United States (4) · South Korea (3) · Australia (2) · Brazil (2) · Canada (2) · France (2) · Italy (2) · Japan (2) · Spain (2) · Taiwan (2) · Turkey (Türkiye) (2) · Argentina (1)
Peter Rossing, MD (2) · Alireza Esteghamati, MD (1) · D.S Choi, MD, PhD (1) · Daniel van Raalte, MD PhD (1) · David ZI Cherney, MD, PhD (1) · Erling B Pedersen, Professor (1) · Ferdinando C Sasso, MD, PhD (1) · Francisco Garcia-Rio, MD (1) · G J Navis, MD, PhD (1) · Gavin W Lambert, BSc PhD (1) · Gen Yasuda, MD (1) · Guillaume Bobrie, MD (1) · H JG Bilo, MD, PhD (1) · Hans-Henrik Parving, MD (1)
PMID 38682786, PMID 35224730, PMID 38449081, PMID 38770818, PMID 39963952, PMID 11128341, PMID 16123474, PMID 16316360, PMID 18496508, PMID 20413516, PMID 20966122, PMID 22792314, PMID 22981148, PMID 24159603, PMID 24866870, PMID 25186534, PMID 27733159, PMID 27753201, PMID 28408434, PMID 28449402, PMID 31816432, PMID 32200854, PMID 32340841, PMID 32516291, PMID 32900785, PMID 33205810, PMID 34271948, PMID 35221224, PMID 35322793, PMID 35998283, PMID 36342964, PMID 36344978, PMID 37171199, PMID 37752566, PMID 39434255, PMID 41665872
2015 (2), 2009 (1), 2014 (1)