2161 completed, 340 unknown, 164 recruiting, 121 terminated. 1252 Not applicable, 331 Phase 1, 299 Phase 3, 239 Phase 4, 164 Phase 2.
Follow Diabetes: new trials by email Literature Review of Diabetes trials Research Report on Diabetes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Na-Phenylbutyrate VAscular Trial Sodium Phenylbutyrate, Placebo - Diabetes | Early Phase 1 | Not yet recruiting | University of Pennsylvania | 30 | 2027-06-01 | 2026-07-28 |
| Glucose, Understanding, Integrated Digital Health, and Engagement (GUIDE) Study Integrated Digital Health (IDH) platform, Provider engagement - Diabetes, Diabetes Type 2 | Not applicable | Not yet recruiting | Yale University | 300 | 2027-03-01 | 2026-09-29 |
| Continuous Glucose Monitoring for In-hospital Management of Type 2 Diabetes Continuous glucose monitoring - Diabetes, Continuous Glucose Monitoring System | Not applicable | Not yet recruiting | Steno Diabetes Center Copenhagen | 314 | 2027-03-01 | 2026-09-01 |
| Effect Of Percutaneous Electrical Nerve Field Stimulation on Symptom Control/Nervous System Activity in Patients w/Diabetes Types 1/2 PERCUTANEOUS ELECTRICAL FIELD NERVE STIMULATION, Sham percutaneous electrical nerve field stimulation - Diabetes, Gastroparesis | Not applicable | Not yet recruiting | Indiana University | 60 | 2027-02-10 | 2026-10-01 |
| Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans Culturally-tailored, enhanced adaption of Diabetes Prevention Program - Diabetes, Physical Activity | Not applicable | Not yet recruiting | University of Missouri, Kansas City | 408 | 2027-01-04 | 2026-06-09 |
| Creating Linked Inpatient CGM for Kids Diabetes, Continuous Glucose Monitoring System | Not yet recruiting | Boston Children's Hospital | 20 | 2027-01-01 | 2026-04-03 | |
| Study Evaluating the Metabolic Effects of pulsENDO Therapy in Adults With Type 2 Diabetes pulsENDO Therapy - Diabetes Type 2, Diabetes | Not applicable | Not yet recruiting | Endogenex, Inc. | 320 | 2027-01-01 | 2026-08-18 |
| Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) Endothelial cell collection - Obesity and Obesity-related Medical Conditions, Diabetes | Recruiting | Bettina Mittendorfer | 100 | 2027-01-01 | 2026-05-07 | |
| Whole Gut Motility Abnormalities Following GLP-1 Receptor Agonist (GLP-1RA) Initiation Gut motility quantification using a capsule after initiating GLP-1RA therapy - Diabetes | Not applicable | Not yet recruiting | The Cleveland Clinic | 20 | 2026-12-01 | 2026-08-25 |
| Pharmacogenetics of Response to Sitagliptin (PRS) Oral Glucose Tolerance Test - Diabetes | Phase 4 | Not yet recruiting | University of Maryland, Baltimore | 400 | 2026-12-01 | 2026-02-18 |
| Unmasking Diabetes in Dialysis With Continuous Glucose Monitoring Continuous Glucose Monitoring (CGM) - End Stage Kidney Disease (ESKD), Hyperglycaemia | Not yet recruiting | Emory University | 180 | 2026-12-01 | 2026-10-19 | |
| PNS to Improve Vascular Function and Limb Health in Veterans Chronically Implanted Neural and Muscular Interface, Peripheral Nerve Stimulation (PNS) - Lower Limb Amputees, Diabetes | Not applicable | Not yet recruiting | VA Office of Research and Development | 42 | 2026-11-02 | 2026-08-21 |
| Feasibility and Performance of Continuous Glucose Monitoring to Guide Computerized Insulin Infusion Therapy in Non-ICU Patients Receiving Corticosteroid Therapy and Specialized Nutrition Dexcom G7 CGM - Diabetes | Not applicable | Not yet recruiting | University of Nebraska | 80 | 2026-10-30 | 2026-10-19 |
| Effects of Meal Macronutrients on Postprandial Lipids High carb then high fat breakfast, High fat then high carb breakfast - Nephrotic Syndrome, Lipodystrophy | Phase 2 | Not yet recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 100 | 2026-10-26 | 2026-10-21 |
| Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults Obesity, Diabetes | Not yet recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 1000 | 2026-10-26 | 2026-10-21 | |
| Genetically Informed Screening for Early-Stage Type 1 Diabetes Diabetes | Not yet recruiting | Massachusetts General Hospital | 150 | 2026-10-15 | 2026-09-08 | |
| Using Healthcare Financing and Digital Technology to Improve Hypertension Prevention and Control in Tanzania Nurse-delivered care using WelTel check-ins and BCC SMS, Community-based peer-support model - Hypertension, Diabetes | Not applicable | Not yet recruiting | Dr. Karen Yeates | 1320 | 2026-10-01 | 2026-08-24 |
| Rowing and Cycling Reduce Inflammation in Early-Stage Type 2 Diabetes Continuous Exercise - Cycling Group, Rowing Ergometer High-Intensity Interval Training, Combined Training Standard - Diabetes | Not applicable | Not yet recruiting | The 95th Hospital of Putian,Putian, Fujian, China | 120 | 2026-10-01 | 2026-08-18 |
| Epalrestat Combined With HAIC, Donafenib and Tislelizumab as First-line Treatment for Patients With Unresectable HCC and Diabetes Epalrestat, Donafenib + Tislelizumab, HAIC - HCC - Hepatocellular Carcinoma, Diabetes | Phase 2 | Not yet recruiting | Haibo Shao | 32 | 2026-10-01 | 2026-09-21 |
| Effectiveness of Personalized Oral Hygiene Advice Delivered by Artificial Intelligence or Dental Professionals Versus Standard Oral Hygiene Advice on Oral and Systemic Health in Community-based Type II Diabetes Patients AI OHI group, Human-OHI group, Control group - Gum Disease, Diabetes | Not applicable | Not yet recruiting | The University of Hong Kong | 105 | 2026-10-01 | 2026-10-01 |
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Insulin Aspart (149) · Insulin Detemir (123) · insulin aspart, insulin aspart protamine drug combination 30:70 (112) · Liraglutide (97) · Insulin Glargine (90) · Metformin (86) · insulin degludec (85) · semaglutide (67) · Insulin, Isophane (49) · Insulin (44) · Exercise (38) · insulin degludec, insulin aspart drug combination (35) · Sitagliptin Phosphate (25) · repaglinide (24) · Continuous Glucose Monitoring (23)
Novo Nordisk A/S (635) · Emory University (33) · Ascensia Diabetes Care (30) · University of Toronto (29) · University of Pennsylvania (28) · Brigham and Women's Hospital (26) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (26) · VA Office of Research and Development (24) · US Department of Veterans Affairs (23) · Mayo Clinic (20) · University of Colorado, Denver (18) · NYU Langone Health (17) · AstraZeneca (16) · University of Pittsburgh (16) · Washington University School of Medicine (16)
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PMID 25504028, PMID 31903692, PMID 32998732, PMID 35044568, PMID 39963952, PMID 23010561, PMID 32267058, PMID 21450987, PMID 21883806, PMID 22193143, PMID 22862847, PMID 23130654, PMID 23186975, PMID 24170235, PMID 26232910, PMID 30615985, PMID 31769496, PMID 33327727, PMID 19245711, PMID 19491536, PMID 21209033, PMID 22055210, PMID 24561125, PMID 26121451, PMID 28205039, PMID 33166419, PMID 35373893, PMID 19878259, PMID 25581159, PMID 26484727, PMID 26663320, PMID 29451706, PMID 29766634, PMID 29862621, PMID 29907893, PMID 30402720, PMID 31215727, PMID 33660198, PMID 33969456, PMID 24812526, PMID 25081590, PMID 26936426, PMID 29687620, PMID 29748996, PMID 32193837, PMID 32827435, PMID 36056351, PMID 37178435, PMID 26582052, PMID 26612062
2009 (32), 2008 (20), 2014 (19), 2015 (19), 2005 (14), 2016 (11), 2004 (5), 2017 (5), 2019 (4), P30DK111024 (4), 2023 (3), OT2HL158287 (3), R01DK060555 (3), 2018 (2), P30AG064199 (2)