9 completed, 3 recruiting, 2 active not recruiting, 2 unknown. 15 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 6, Active not recruiting 2, Recruiting 2, Unknown 2, Enrolling by invitation 1, Not yet recruiting 1, Withdrawn 1 |
Follow Deprescribing: new trials by email Literature Review of Deprescribing trials Research Report on Deprescribing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Impact of Pre-visit Priming for Medications Pre-visit prompts - Deprescribing, Statin Prescribing | Not applicable | Enrolling by invitation | Brigham and Women's Hospital | 1700 | 2026-06-10 | 2026-10-13 |
| General Practitioner & Pharmacist Support for Discontinuing Long-term Antidepressants in Clinically Stable Patients GPS-AD intervention - Deprescribing, Antidepressant | Not applicable | Not yet recruiting | University Ghent | 324 | 2026-03-01 | 2026-02-09 |
| Deprescribing in Outpatient Internal Medicine Practices medication review - Deprescribing | Not applicable | Completed | Wake Forest University Health Sciences | 26 | 2025-11-12 | 2026-07-06 |
| Population Health Approach to Optimizing Medications in Older Adults Patient-tailored deprescribing assessment and intervention - Medication Adverse Effects, Older Adults (65 Years and Older) | Not applicable | Active not recruiting | Cedars-Sinai Medical Center | 100 | 2025-05-19 | 2026-03-27 |
| Co-development of a Deprescribing Program for Older Community-dwelling Patients Treated With Anticholinergic/Sedative Medications Focus groups and workshops of healthcare professionals and patients - Deprescribing | Completed | Hospices Civils de Lyon | 35 | 2025-04-28 | 2026-06-26 | |
| RAK-PRIDE: Optimizing Proton Pump Inhibitor Use Through Education and Intervention Control (Standard treatment), Pharmacist-Led Educational Intervention - Proton Pump Inhibitors, Deprescribing | Not applicable | Recruiting | RAK Medical and Health Sciences University | 479 | 2025-03-01 | 2025-03-12 |
| Leveraging Behavioral Science to Improve Medicine Optimization Conversations With Older Adults Anticipated long-term use of medication, Period re-evaluation of medication - Deprescribing | Not applicable | Completed | University of Michigan | 2420 | 2024-11-01 | 2025-09-26 |
| Prevalence of Inappropriate Prescriptions and Omitted Therapies in Hospitalized Elderly: STOPP/START Criteria Analysis medication review and deprescribing - Polypharmacy (People Under Treatment With 5 or More Drugs), Elderly (People Aged 65 or More) | Completed | Regione del Veneto - AULSS n. 7 Pedemontana | 100 | 2024-07-17 | 2025-10-02 | |
| DEprescribing: Perceptions of PAtients Living With Advanced Cancer Semi-directed individual interviews, The self-administered questionnaires, rPATD and BMQ, The self-administered FCCHL (Functional, Communicative and Critical Health Literacy) / HLS14 (14-item health literacy scale) - Deprescribing, Palliative Care | Recruiting | Nantes University Hospital | 325 | 2024-02-28 | 2026-09-25 | |
| Deprescribing dRrugs for Overactive Bladder in General Practice (DROP) deprescribing-intervention - Overactive Bladder, Deprescribing | Not applicable | Active not recruiting | Anne Estrup Olesen | 72 | 2023-12-01 | 2025-12-02 |
| Effectiveness of a Joint General Practitioner-Pharmacist Intervention on Benzodiazepine Deprescribing in the Elderly GP - pharmacist collaboration and pharmacist motivational interviewing - Primary Care, Health Plan Implementation | Not applicable | Recruiting | Nantes University Hospital | 400 | 2023-10-16 | 2026-06-24 |
| Shared Decision Making About Medication Use for People With Multiple Health Problems Educational Materials - Polypharmacy, Dementia | Not applicable | Completed | Johns Hopkins University | 22 | 2023-05-22 | 2024-11-27 |
| Testing the SNOWDROP Intervention: Using a Clinical Decision Support System and Patient Portal for Falls Prevention Among Older Patients in Primary Care CDSS, Patient Portal - Fall, Fall Injury | Not applicable | Completed | University of Amsterdam | 85 | 2022-11-21 | 2024-01-10 |
| Spread and Scale of a Polypharmacy App MedReviewRx - Polypharmacy, Deprescribing | Not applicable | Unknown | Centre for Innovation and Research in Aging, Canada | 1000 | 2021-08-01 | 2021-06-16 |
| MedSafer E-care: an Automated Deprescribing Solution (E-CARE Study) Electronic decision support for deprescribing (MedSafer tool) - Polypharmacy, Deprescribing | Not applicable | Withdrawn | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2021-01-01 | 2023-11-02 | |
| Effect of Medication Management at Home Via Pharmacy Home Televisits Medication management via televisit to home - Polypharmacy, Deprescribing | Not applicable | Completed | VA Office of Research and Development | 304 | 2020-07-16 | 2026-01-08 |
| Reducing Costs by Deprescribing Medications Deprescribing Intervention, Usual Care - Polypharmacy, Deprescribing | Not applicable | Completed | The University of Texas Health Science Center, Houston | 419 | 2019-12-09 | 2022-11-22 |
| Efficacy and Feasibility of De-prescribing Rounds in a Singapore Rehabilitative Hospital- a Pilot Randomized Controlled Trial Weekly MDT deprescribing rounds for certain drugs - Deprescribing, Multi-disciplinary | Not applicable | Unknown | Bright Vision Hospital | 260 | 2018-11-28 | 2020-05-20 |
| How do Older Adults and Caregivers Feel About Their Medications? rPATD Questionnaire - Deprescribing | Completed | Monash University | 1057 | 2017-07-25 | 2018-04-04 |
Drug-Related Side Effects and Adverse Reactions (4) · Multiple Chronic Conditions (2) · Anxiety Disorders (1) · Cognitive Dysfunction (1) · Dementia (1) · Depression (1) · Neoplasms (1) · Peptic Ulcer (1) · Urinary Bladder, Overactive (1)
Chemically-Induced Disorders (4) · Pathological Conditions, Signs and Symptoms (3) · Chronic Disease (2) · Disease Attributes (2) · Mental Disorders (2) · Pathologic Processes (2) · Behavior (1) · Behavioral Symptoms (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Cognition Disorders (1) · Digestive System Diseases (1) · Duodenal Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1)
Deprescriptions (2) · Medication Review (2) · Focus Groups (1) · Functional Status (1) · Methods (1) · Patient Portals (1)
Nantes University Hospital (2) · Anne Estrup Olesen (1) · Brigham and Women's Hospital (1) · Bright Vision Hospital (1) · Cedars-Sinai Medical Center (1) · Centre for Innovation and Research in Aging, Canada (1) · Hospices Civils de Lyon (1) · Johns Hopkins University (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Monash University (1) · RAK Medical and Health Sciences University (1) · Regione del Veneto - AULSS n. 7 Pedemontana (1) · The University of Texas Health Science Center, Houston (1) · University Ghent (1) · University of Amsterdam (1)
United States (7) · France (3) · Canada (2) · Singapore (2) · Denmark (1) · Italy (1) · Netherlands (1) · United Arab Emirates (1)
Anne E Olesen, Professor (1) · Ariel Green, MD, MPH, PhD (1) · Arwa Alnahdi (1) · Carole Goodine, Pharm D (1) · Ellen Van Leeuwen, MD, PhD (1) · Emily McDonald, MD (1) · Emily McDonald, MDCM (1) · Holly M Holmes, MD,MS (1) · Imran Rashid Rangraze (1) · Julia C.M. van Weert (1) · Julia Clements, PharmD (1) · Lauren Rachel Moo, MD (1) · Luca Pellizzari Dr. Pellizzari, DR (1)
PMID 11298072, PMID 14687321, PMID 25183716, PMID 25385826, PMID 25798575, PMID 34674645, PMID 34727956, PMID 37711743, PMID 37960887, PMID 39042875, PMID 39163415, PMID 39908544, PMID 40445620, PMID 40767505
K01AG076865 (1), K23AG054742 (1), P30AG024968 (1)