4 completed, 3 active not recruiting, 1 enrolling by invitation, 1 recruiting. 8 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Active not recruiting 3, Completed 3, Recruiting 1, Withdrawn 1 |
| Phase 4 | 1 | Enrolling by invitation 1 |
Follow Deprescriptions: new trials by email Literature Review of Deprescriptions trials Research Report on Deprescriptions
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Deprescribing Beta-Blockers in Elders With Heart Failure With Preserved Ejection Fraction (DEPRESCRIBE-HFpEF) Placebo (matching), Beta-blockers - Heart Failure, HFpEF | Phase 4 | Enrolling by invitation | Weill Medical College of Cornell University | 240 | 2026-02-02 | 2026-10-16 |
| Factors Determining the Rate of Adoption of Pharmaceutical Recommendations by Patients in Primary Care Following a Medication Review by a Pharmacist medication review and deprescribing - Polypharmacy (People Under Treatment With 5 or More Drugs), Polypharmacy, Decision-making | Not applicable | Active not recruiting | Université Catholique de Louvain | 123 | 2026-01-12 | 2026-06-01 |
| Improving Medication Management in World Trade Center Responders Educational brochure for deprescribing - Polypharmacy | Not applicable | Active not recruiting | Icahn School of Medicine at Mount Sinai | 23 | 2025-04-08 | 2026-10-20 |
| Prescribing Outcomes of a GP-Targeted Deprescribing Educational Intervention: A Cluster Randomized Trial Medication Reviews and Deprescribing - Medication Overuse, Deprescriptions | Not applicable | Active not recruiting | University of Crete | 200 | 2024-11-18 | 2026-02-09 |
| Prevalence of Inappropriate Prescriptions and Omitted Therapies in Hospitalized Elderly: STOPP/START Criteria Analysis medication review and deprescribing - Polypharmacy (People Under Treatment With 5 or More Drugs), Elderly (People Aged 65 or More) | Completed | Regione del Veneto - AULSS n. 7 Pedemontana | 100 | 2024-07-17 | 2025-10-02 | |
| Deprescribing Intervention for Patients With Chronic Kidney Disease Deprescribing - Chronic Kidney Diseases | Not applicable | Recruiting | Hamad Medical Corporation | 424 | 2024-02-19 | 2025-10-01 |
| Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults Acupuncture, Yoga, Deprescribing - Anxiety, Insomnia | Not applicable | Completed | Vanderbilt University Medical Center | 23 | 2023-12-14 | 2026-09-30 |
| Mental Health Assessment and Prescribing by Alberta Pharmacists Standard Pharmacist Care, Reviewed Questionnaire tool results with participant, Patient Clinical Assessment - Major Depressive Disorder, Generalized Anxiety Disorder | Not applicable | Completed | University of Alberta | 13 | 2023-03-22 | 2025-07-04 |
| Reducing Use of Sleep Medications Assisted by a Digital Insomnia Intervention Cognitive Behavioral Therapy for Insomnia, Deprescribing - Insomnia | Not applicable | Completed | VA Office of Research and Development | 36 | 2022-09-22 | 2025-04-11 |
| MedSafer E-care: an Automated Deprescribing Solution (E-CARE Study) Electronic decision support for deprescribing (MedSafer tool) - Polypharmacy, Deprescribing | Not applicable | Withdrawn | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2021-01-01 | 2023-11-02 | |
| Does the New Fall- and Fracture Prevention Initiative in Oslo Have Effect? Implement coordination of care with multifactorial falls- and fracture risk assessment and tailored intervention - Fall Injury, Hip Fractures | Unknown | Norwegian Institute of Public Health | 121000 | 2012-01-01 | 2023-01-11 |
Sleep Initiation and Maintenance Disorders (2) · Anxiety Disorders (1) · Depressive Disorder, Major (1) · Drug-Related Side Effects and Adverse Reactions (1) · Frailty (1) · Generalized Anxiety Disorder (1) · Heart Failure (1) · Hip Fractures (1) · Prescription Drug Overuse (1) · Psychological Well-Being (1) · Renal Insufficiency, Chronic (1)
Hamad Medical Corporation (1) · Icahn School of Medicine at Mount Sinai (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Norwegian Institute of Public Health (1) · Regione del Veneto - AULSS n. 7 Pedemontana (1) · University of Alberta (1) · University of Crete (1) · Université Catholique de Louvain (1) · VA Office of Research and Development (1) · Vanderbilt University Medical Center (1) · Weill Medical College of Cornell University (1)
United States (4) · Canada (2) · Belgium (1) · Greece (1) · Italy (1) · Qatar (1)
Abdullah Hamad, MD (1) · Adam D. Bramoweth, PhD (1) · Ahmed Awaisu, Ph.D. (1) · Andrew Ambrosy, MD, MPH (1) · Emily McDonald, MDCM (1) · Gro Idland, PhD (1) · Gurjeet Birdee (1) · Hasan Al-Malki, MD (1) · Ioanna Tsiligianni, MD, PhD (1) · Luca Pellizzari Dr. Pellizzari, DR (1) · Manon de Montigny (1) · Olivia Dalleur, PhD, Professor (1) · Parag Goyal, MD, MSc (1) · William Hung, MD, MPH (1) · Yazid Al Hamarneh, BSc (Pharm), PhD, CDM (1)
PMID 41358144, PMID 41916794, PMID 42050101
I21RX003732 (1), R01AG091005 (1), R24AG064025 (1), U01OH012473 (1)