16 completed, 4 recruiting, 3 active not recruiting, 3 unknown. 22 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 22 | Completed 12, Recruiting 4, Active not recruiting 2, Unknown 2, Not yet recruiting 1, Withdrawn 1 |
| Phase 1 | 1 | Terminated 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Ankyloglossia: new trials by email Literature Review of Ankyloglossia trials Research Report on Ankyloglossia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectivity of P1821, a Novel Tongue Strengthening and Endurance Enhancing Speech Flow Exercise P1821 - Ankyloglossia, Impairment of Speech | Not applicable | Recruiting | Dream Video LLC | 100 | 2026-11-01 | 2026-11-04 |
| SNIP follow-on Case Series Using v3 Device Frenectomy of anterior ankylogossia using the novel device - Ankyloglossia | Not applicable | Not yet recruiting | Europa Life Sciences Limited | 6 | 2026-10-01 | 2026-09-04 |
| Ankyloglossia and Breastfeeding TABBY - Ankyloglossia, Breastfeeding | Not yet recruiting | Ariana Muñoz San Miguel | 146 | 2026-09-01 | 2026-08-11 | |
| Case Series of Infants With Anterior Ankyloglossia Being Treated by the Sublingual Neonatal Incision Platform Device Frenectomy of anterior ankylogossia using the novel device - Ankyloglossia | Not applicable | Active not recruiting | Europa Life Sciences Limited | 6 | 2026-03-10 | 2026-06-18 |
| Long-term Follow-up of Infant Frenotomy/Frenectomy Through Early Childhood Tongue tie release - Ankyloglossia | Enrolling by invitation | University of Alberta | 500 | 2025-06-01 | 2026-09-16 | |
| The Impact of Post-Frenotomy Massages on Ankyloglossia Recurrence and Feeding Outcomes Post-frenotomy massage - Ankyloglossia | Not applicable | Recruiting | Isaac Elijah | 150 | 2025-01-27 | 2026-08-03 |
| Post-Procedural Manual Manipulation for Infant Ankyloglossia Post-frenotomy manual manipulation - Ankyloglossia, Breastfeeding Support | Not applicable | Recruiting | Georgetown University | 110 | 2024-10-15 | 2025-02-17 |
| Healing Efficacy of Diode Laser in Lingual Frenectomy Lingual Frenectomy using 940nm Diode Laser, Lingual Frenectomy using High-frequency Electrosurgery - Ankyloglossia, Tongue-tie | Not applicable | Recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 53 | 2024-10-01 | 2026-04-30 |
| Frenuloplasty for Speech and Myofunctional Outcomes Lingual frenuloplasty - Ankyloglossia, Speech Delay | Not applicable | Unknown | The Oregon Clinic | 50 | 2024-07-01 | 2024-04-03 |
| Breastfeeding Duration and Tongue-tie in Neonates. Frenotomy - Infant Nutrition Disorders | Not applicable | Completed | Hvidovre University Hospital | 100 | 2023-11-17 | 2025-09-19 |
| Use of Inhaled Colostrum to Control Pain in Neonatal Frenotomy and Comparison to Inhaled Lavender Essential Oil Colostrum - Pain, Ankyloglossia | Not applicable | Completed | Parc de Salut Mar | 142 | 2023-09-18 | 2025-03-11 |
| Physiotherapy in the Treatment of Breastfeeding Difficulties Myofunctional therapy - Breastfeeding, Ankyloglossia | Not applicable | Completed | Universidad de Almeria | 200 | 2023-07-01 | 2024-07-31 |
| Prevalence of Tongue Anomalies in Egyptian Children no intervention - Tongue; Anomaly | Completed | Cairo University | 250 | 2023-03-25 | 2023-10-17 | |
| Tongue Mobility in Patients With Ankyloglossia Following Frenectomy Frenectomy - Ankyloglossia | Completed | Hanoi Medical University | 60 | 2022-12-01 | 2026-09-24 | |
| Lingual Frenulum in Newborn Infants (LINNE) Frenotomy, Oral physiotherapy - Tongue Tie, Frenulum Breve | Not applicable | Active not recruiting | University of Oulu | 300 | 2022-10-03 | 2026-01-08 |
| The Effect of Pre-emptive Analgesia on the Postoperative Pain in Children Undergoing Pediatric Stomatology Day Surgeries ibuprofen suppository - Ankyloglossia, Oral Mucoceles | Not applicable | Completed | The Children's Hospital of Zhejiang University School of Medicine | 120 | 2022-09-01 | 2023-05-26 |
| Ankyloglossia and Its Effects on Breastfeeding, Feeding and Speech Disorders. A Prospective Study From Birth to 4 Years of Age. TABBY, Lingual Frenulum Protocol with Scores for Infants., Hazelbaker Assessment Tool for Lingual Frenulum Function - Ankyloglossia, Breastfeeding | Active not recruiting | Erasme University Hospital | 348 | 2022-05-23 | 2026-04-06 | |
| Evaluation of the Effects of Tongue-Tie and Upper Lip-Tie Tongue-tie, Upper Lip-tie | Completed | Ankara Yildirim Beyazıt University | 67 | 2022-05-01 | 2025-02-14 | |
| Dedicated Lactation Support in Infants With Tongue - Tie; a Randomised Control Trial phrenectomy, Increased lactation support - Ankyloglossia, Breast Feeding, Exclusive | Not applicable | Withdrawn | Princess Anna Mazowiecka Hospital, Warsaw, Poland | 2022-03-08 | 2022-07-21 | |
| The Use of Lavender vs Vanilla Essential Oil as Complementary Analgesia for Frenotomy in Healthy Newborns Case (use of inhaled vanilla essential oil), Control (use of inhaled lavender essential oil) - Ankyloglossia | Not applicable | Unknown | Parc de Salut Mar | 142 | 2021-05-10 | 2021-04-30 |
Showing 20 of 31. Sign in to see all of them.
Breast Feeding (13) · Pain (3) · Pain, Postoperative (2) · lip tie (2) · Bottle Feeding (1) · Congenital Abnormalities (1) · Dentofacial Deformities (1) · Glossitis, Benign Migratory (1) · Hyperthermia (1) · Infant Nutrition Disorders (1) · Lactation Disorders (1) · Language Development Disorders (1) · Macroglossia (1) · Motor Activity (1)
Stomatognathic Diseases (31) · Behavior (14) · Feeding Behavior (14) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Congenital Abnormalities (2) · Pain (2) · Pathologic Processes (2) · Postoperative Complications (2) · Stomatognathic System Abnormalities (2) · Body Temperature Changes (1) · Breast Diseases (1) · Communication Disorders (1)
Oral Frenectomy (5) · Therapeutics (2) · Benzocaine (1) · Lasers, Semiconductor (1) · Myofunctional Therapy (1) · Physical Therapy Modalities (1) · Sugars (1) · lavender oil (1)
The Oregon Clinic (4) · Parc de Salut Mar (3) · Europa Life Sciences Limited (2) · Ankara Yildirim Beyazıt University (1) · Ariana Muñoz San Miguel (1) · Cairo University (1) · Dream Video LLC (1) · Erasme University Hospital (1) · Georgetown University (1) · Hanoi Medical University (1) · Hvidovre University Hospital (1) · IRCCS Burlo Garofolo (1) · Isaac Elijah (1) · Princess Anna Mazowiecka Hospital, Warsaw, Poland (1) · Tel-Aviv Sourasky Medical Center (1)
United States (6) · Spain (5) · United Kingdom (2) · Vietnam (2) · Belgium (1) · Canada (1) · China (1) · Denmark (1) · Egypt (1) · Finland (1) · Israel (1) · Italy (1) · Poland (1) · South Korea (1) · Turkey (Türkiye) (1)
Ana Bengoetxea, PhD (1) · Atle Klovning, MD. PhD (1) · Aung Soe (1) · Aung Soe, MBChB MSc FRCPCH AFHEA (1) · Bobak A Ghaheri, MD (1) · Bobak Ghaheri, MD (1) · Chiara Navarra, DDS MSc PhD (1) · Diana Skaaning (1) · Earl H Harley, MD (1) · Fangqi Gong, doctor (1) · Jennifer Foucart, PhD (1) · Laura J Maroye, PhD Student (1) · Maddalena Chermetz, DDS MSc (1)
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