15 completed, 12 unknown, 4 recruiting, 3 not yet recruiting. 25 Not applicable, 2 Phase 2, 2 Phase 4, 1 Phase 1.
Follow Van der Woude syndrome: new trials by email Literature Review of Van der Woude syndrome trials Research Report on Van der Woude syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Evaluation of the Retention of Fissure Sealants Applied Following Guided Biofilm Therapy and Conventional Polishing Device: Guided Biofilm Therapy with erythritol, Device: Conventional Polishing - Pit and Fissure Sealant Retention, Dental Caries | Not applicable | Not yet recruiting | Marmara University | 80 | 2026-07-20 | 2026-07-24 |
| Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior Teeth Dental Enamel, Dental Enamel Hypomineralization | Recruiting | Foundation University Islamabad | 420 | 2025-12-27 | 2026-05-26 | |
| Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive Function Short-Chain Fatty Acid Colon-Delivery Capsules, Placebo capsules, Lipopolysaccharide (LPS) - Endotoxemia, Inflammation | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 56 | 2025-10-24 | 2026-07-20 |
| Comparison of the Efficacy of Three Preventive Methods to Reduce the Incidence of Coronal Caries in Schoolchildren Glass ionomer pit and fissure sealant plus fluoride varnish, Pit and fissure sealant with Giomer® technology, Fluoride varnish - Caries Prevention | Not applicable | Recruiting | Universidad Nacional Autonoma de Mexico | 204 | 2025-09-01 | 2025-09-24 |
| Wear Resistance Of Bioactive With And Without Etching Vs. Conventional Resin-Based Fissure Sealants Bioactive Sealant with Etching: Participants in this group received a fluoride-releasing bioactive pit and fissure sealant (BeautiSealant, Shofu) applied after etching the tooth surface with 37% phosp, Bioactive Sealant without Etching: In this group, the same bioactive sealant (BeautiSealant, Shofu) was applied directly without acid etching. This simplified technique evaluates the sealant's effecti, Conventional Resin-Based Sealant with Etching (Control): This group received a conventional resin-based sealant (Fisseal, Promedica) following standard acid etching. This technique represents the trad - Pit and Fissure Caries | Not applicable | Not yet recruiting | Cairo University | 23 | 2025-08-01 | 2025-06-12 |
| Effect of Music on Anxiety, Pulse Rate, and Pain During Fissure Sealant Application in Children Music intervention 1, Music intervention 2 - Dental Anxiety, Pediatric Dental Patients | Not applicable | Completed | Nigde Omer Halisdemir University | 90 | 2025-05-24 | 2026-04-22 |
| Evaluation of the Clinical Success of Hydrophilic Fissure Sealants pit and fissure sealant - Pit and Fissure Caries (Disorder), Pit and Fissure Sealants | Not applicable | Active not recruiting | Afyonkarahisar Health Sciences University | 250 | 2025-03-01 | 2025-12-03 |
| Evaluation of Two Pit and Fissure Sealants Treated by Two Remineralizing Agents in Resin Restorations Group 1 :Teeth treated with Fisseal, Promedica Dental Material GmbH after treating with Biflourid, Group 2 :Teeth treated with Fisseal, Promedica Dental Material GmbH after treating with MI Paste, Group 3 : Teeth treated with prevent seal, Itena, North America after treating with Biflourid - Retention, Fissure Sealants | Not applicable | Completed | Ismail Dahshan | 44 | 2025-02-28 | 2026-07-15 |
| Dry-Shield vs Rubber Dam During Fissure Sealant Placement Pit and fissure sealant (Conseal F) - Pit and Fissure Sealants, Dental Caries Prevention | Not applicable | Completed | Suez Canal University | 30 | 2025-02-26 | 2026-06-03 |
| Resin Infiltrate as Pit and Fissure Sealant in Permanent Molars ICON resin infiltration Material group in vivo, Resin-based fissure sealant group in vivo, ICON resin infiltration in vitro - Resin Infiltration, Pit and Fissure Sealant | Phase 4 | Not yet recruiting | Tanta University | 86 | 2025-01-04 | 2024-12-11 |
| Clinical Evaluation of Two Different Pit and Fissure Sealants Resin-based flowable filling material - Pit and Fissure Sealants, Molar Incisor Hypomineralization | Not applicable | Recruiting | Baskent University | 126 | 2024-11-18 | 2025-01-17 |
| Clinical Efficiency of Bioactive Pit and Fissure Sealant BioCoat® by Premier®, UltraSeal XT™ plus by Ultradent - Pit and Fissure Sealant | Phase 2 | Unknown | Cairo University | 40 | 2024-08-01 | 2024-07-10 |
| Clinical Evaluation of Pit and Fissure Sealants Biocoat Pit and fissure sealant, Fissurit FX Pit and fissure sealant - Pit and Fissure Sealants | Completed | Canan Bayraktar Nahir | 63 | 2023-08-01 | 2025-05-23 | |
| Effect of Glass-Ionomer Sealing Technique on Hypersensitive Teeth With Molar Incisor Hypomineralisation GIC on MIH - Hypersensitive, Molar Incisor Hypomineralization | Not applicable | Unknown | University Medicine Greifswald | 18 | 2023-05-01 | 2023-07-14 |
| Retention Rate and Caries Preventive Effect of Preheated Flowable Resin Composite Used as a Pit and Fissure Sealant Pre-heating of flowable resin composite used as a pit and fissure sealant., Conventional resin fissure sealant - Pit and Fissure Sealant | Not applicable | Completed | Cairo University | 28 | 2022-11-20 | 2024-05-14 |
| Comparison Between Resin Based and Glass Ionomer Based Hydrophilic Fissure Sealants Sealing deep pits and fissures - Caries | Not applicable | Unknown | Cairo University | 48 | 2022-02-01 | 2021-11-19 |
| Retention Rate of Self-etch Resin Based Sealant With and Without Prior Sandblasting Self etch Pit and fissure sealant application (prevent seal), Self etch Pit and fissure sealant application (prevent seal) with prior sandblasting, Total etch resin based sealant ultraseal xt - Caries; Initial, Pit and Fissure Caries | Not applicable | Unknown | Cairo University | 30 | 2021-07-01 | 2021-06-18 |
| Retention of a Flowable Resin-based Sealant With Two Types of Adhesives Scotchbond Universal 3M, Single Bond 3M - Caries,Dental, Pit and Fissure Caries | Not applicable | Unknown | National University of San Marcos, Peru | 50 | 2021-06-01 | 2021-06-30 |
| Retention of Flowable Resin With Sprg and of a Flowable Resin in First Permanent Molars Giomer Beautifil flow plusF03 Shofu-Japan, Tetric N flow ivoclar vivadent-Germany - Pit and Fissure Sealant | Not applicable | Unknown | Catherine Christie Ruiz Yasuda | 60 | 2021-03-01 | 2021-01-08 |
| Comparing Bond Strength,Microleakage and Clinical Performance of Three Pit and Fissure Sealants Clinpro sealant, Embrace wetbond sealant, Triage sealant - Caries Prevention | Not applicable | Unknown | Sarah Emad Ali El-Din | 100 | 2019-07-03 | 2020-02-17 |
Showing 20 of 36. Sign in to see all of them.
Dental Caries (10) · Molar Hypomineralization (2) · Autistic Disorder (1) · Dental Enamel Hypomineralization (1) · Dental Enamel Hypoplasia (1) · Endotoxemia (1) · Exanthema (1) · Hypersensitivity (1) · Inflammation (1) · Inhibition, Psychological (1) · Sepsis (1)
Stomatognathic Diseases (13) · Tooth Diseases (13) · Tooth Demineralization (10) · Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Developmental Defects of Enamel (3) · Stomatognathic System Abnormalities (3) · Tooth Abnormalities (3) · Dental Enamel Hypomineralization (2) · Infections (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Systemic Inflammatory Response Syndrome (2) · Autism Spectrum Disorder (1) · Bacteremia (1)
Pit and Fissure Sealants (7) · Ultra Seal XT (3) · CMW cement (1) · Clinpro Sealant (1) · Endotoxins (1) · Fuji VII (1) · Glass Ionomer Cements (1) · In Vitro Techniques (1) · Lipopolysaccharides (1) · Oxytocin (1) · Technology, High-Cost (1) · glass ionomer (1) · microcrystalline cellulose (1) · sodium fluoride topical preparation (1)
Cairo University (7) · Faculty Sao Leopoldo Mandic Campinas (2) · Fernanda Miori Pascon (2) · Afyonkarahisar Health Sciences University (1) · Baskent University (1) · Canan Bayraktar Nahir (1) · Catherine Christie Ruiz Yasuda (1) · Centre Hospitalier Universitaire de Nice (1) · Foundation University Islamabad (1) · Ismail Dahshan (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Marmara University (1) · Medical University of Vienna (1) · National University of San Marcos, Peru (1) · Nigde Omer Halisdemir University (1)
Egypt (7) · Turkey (Türkiye) (5) · China (2) · Peru (2) · Austria (1) · Belgium (1) · Brazil (1) · Canada (1) · Chile (1) · France (1) · Germany (1) · Hong Kong (1) · Italy (1) · Mexico (1) · Pakistan (1)
Ana Carolina G Luciano, DDS (1) · Baoying Liu, PhD (1) · Boushra Dalile, PhD (1) · Catherine Ruiz Yasuda, Doctor (1) · Christian H Splieth, Prof. (1) · Cynthia Kar Yung Yiu, FHKAM,FCDSHK (1) · Dr. Fizza Sherazi, BDS (1) · Dr. Sahza Hatibov-Kofman, D.D.S.FRCD (1) · Eman Abouauf, Ass.prof (1) · Heba Helal (1) · Iman I ElSayad, Professor (1) · Jose Carlos P Imparato, PhD (1) · Juliana Camargo (1) · Kamila Kantovitz, Phd (1) · Kelly MS Moreira, MS Student (1)
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