7 completed. 7 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 7 |
Follow Cryptococcosis: new trials by email Literature Review of Cryptococcosis trials Research Report on Cryptococcosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study of AK1820 (Isavuconazonium Sulfate) for the Treatment of Deep Mycosis AK1820, Voriconazole - Deep Mycosis | Phase 3 | Completed | Asahi Kasei Therapeutics Corporation | 103 | 2018-04-16 | 2021-05-14 |
| Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis Sertraline - Cryptococcal Meningitis, Fungal Meningitis | Phase 3 | Completed | University of Minnesota | 460 | 2015-03-09 | 2020-06-09 |
| Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC Immunochromatographic HAT tests (DSD), Card Agglutination Trypanosoma Test, TB POC Nucleic Acid Amplification Test (Molbio Diagnostics) - Neurological Disorders, Cerebral Malaria | Phase 3 | Completed | Institute of Tropical Medicine, Belgium | 352 | 2012-09-01 | 2016-01-18 |
| A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection ITCZ Oral Solution, ITCZ-IV - Mycoses, Candidiasis | Phase 3 | Completed | Janssen Pharmaceutical K.K. | 55 | 2008-01-01 | 2013-07-25 |
| Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P02095) Posaconazole oral suspension - Mycoses | Phase 3 | Completed | Merck Sharp & Dohme LLC | 2001-04-01 | 2017-03-10 | |
| Open Label Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P00041) Posaconazole - Mycoses | Phase 3 | Completed | Merck Sharp & Dohme LLC | 336 | 1998-12-01 | 2017-03-10 |
| Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS Fluconazole, Amphotericin B - Meningitis, Cryptococcal, HIV Infections | Phase 3 | Completed | Pfizer | 330 | 2011-03-14 |
Aspergillosis (4) · Candidiasis (3) · Meningitis, Cryptococcal (3) · Mycoses (3) · Meningitis (2) · AIDS-Related Opportunistic Infections (1) · Acquired Immunodeficiency Syndrome (1) · Blastomycosis (1) · HIV Infections (1) · Histoplasmosis (1) · Invasive Fungal Infections (1) · Malaria, Cerebral (1) · Meningitis, Bacterial (1) · Meningitis, Fungal (1)
Bacterial Infections and Mycoses (7) · Infections (7) · Mycoses (4) · Central Nervous System Diseases (3) · Central Nervous System Fungal Infections (3) · Central Nervous System Infections (3) · Neuroinflammatory Diseases (3) · Meningitis, Fungal (2) · Nervous System Diseases (2) · Actinomycetales Infections (1) · Agranulocytosis (1) · Bacterial Infections (1) · Blood-Borne Infections (1) · Central Nervous System Bacterial Infections (1)
Amphotericin B (1) · Fluconazole (1) · Sertraline (1) · Voriconazole (1) · isavuconazole (1) · posaconazole (1)
Merck Sharp & Dohme LLC (2) · Asahi Kasei Therapeutics Corporation (1) · Institute of Tropical Medicine, Belgium (1) · Janssen Pharmaceutical K.K. (1) · Pfizer (1) · University of Minnesota (1)
Japan (2) · Democratic Republic of the Congo (1) · Uganda (1) · United States (1)
Armstrong D (1) · David B Meya, MBCHB MMed (1) · David R Boulware, MD MPH (1) · Dismukes W (1) · Emmanuel Bottieau, MD (1) · Joshua Rhein, MD (1) · Marleen Boelaert, MD, PhD (1) · Powderly W (1)
PMID 18813103, PMID 19485785, PMID 30256903, PMID 30325463, PMID 30345376, PMID 31242860, PMID 31345462, PMID 32843994, PMID 33677986, PMID 35191210, PMID 36303432, PMID 36307059, PMID 38152404, PMID 39972326
R01NS086312 (1)