37 completed, 7 recruiting, 6 not yet recruiting, 5 active not recruiting. 46 Not applicable, 3 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 46 | Completed 30, Not yet recruiting 5, Recruiting 4, Active not recruiting 3, Unknown 3, Enrolling by invitation 1 |
| Phase 4 | 3 | Completed 3 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Crowding: new trials by email Literature Review of Crowding trials Research Report on Crowding
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Timing, Trajectories and Prediction in Severe Dental Crowding: The Create SPACE (cSPACE) Early first premolar extraction with observation, Early first premolar extraction with planned fixed orthodontic treatment - Crowding of Teeth, Malocclusion; Displaced Teeth | Not applicable | Not yet recruiting | Vastra Gotaland Region | 300 | 2027-03-01 | 2026-11-02 |
| Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment Self-etch adhesive, One-Step Adhesive, Conventional Bonding Technique - Malaligned Teeth, Crowding of Teeth | Not applicable | Not yet recruiting | Foundation University Islamabad | 34 | 2027-01-15 | 2026-08-10 |
| Evaluation of Intraoral Scanning vs Conventional Impression in Assessing Dental Crowding Introral Scanner, Conventional Alginate Impression - Dental Crowding | Not yet recruiting | Cairo University | 31 | 2027-01-01 | 2026-11-10 | |
| Orthodontic Treatment Outcomes of Self Ligating System Compared to Clear Aligner System self ligating bracket, Clear aligner - Angle Class I Maloclussion, Dental Crowding | Not applicable | Not yet recruiting | University of Baghdad | 42 | 2026-09-15 | 2026-07-07 |
| Clinical Performance of Direct-Printed Versus Thermoformed Aligners Direct-Printed Aligner, Thermoformed aligner - Angle Class I Malocclusion, Dental Crowding | Not applicable | Recruiting | University of Baghdad | 34 | 2026-06-01 | 2026-06-09 |
| Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth Separation Elastomeric separators, Nickel-Titanium separators - Dental Crowding, Malocclusion, Angle Class I | Not applicable | Not yet recruiting | 3D-Aligners | 30 | 2026-06-01 | 2026-05-15 |
| Accuracy and Time Efficiency of AI Versus Manual Segmentation in Adult Crowding Using Aligner Software Automated tooth segmentation and manual segmentation - Dental Crowding | Active not recruiting | Dina ahmed | 155 | 2026-03-15 | 2026-11-05 | |
| Accuracy and Periodontal Outcomes of Three Interproximal Enamel Reduction Techniques During Clear Aligner Therapy Manual Arm, Motor Driven Arm, Abrasive Arm - Dental Crowding,Interproximal Enamel Reduction, Malocclusion, Angle's Class | Not applicable | Not yet recruiting | Riyadh Elm University | 75 | 2026-03-01 | 2026-01-30 |
| The Predictability of Directly Printed Versus Thermoformed Clear Aligners Direct-printed aligner (Graphy), Thermoformed aligner - Class I Malocclusion, Crowded Teeth | Not applicable | Enrolling by invitation | University of Baghdad | 36 | 2026-02-15 | 2026-04-15 |
| Validity of Ashley Howe's Analysis for the Prediction of the Extraction Treatment Decision in Orthodontic Patients at the Permanent Dentition Stage Ashley Howe's Analysis - Dental Crowding | Recruiting | Cairo University | 50 | 2026-02-01 | 2026-06-22 | |
| Clinical Performance of the I-arch System During the Initial Stage of Orthodontic Treatment The use of 0.016×0.014 copper nickel titanium arch wire during the alignment stage., Use of 0.014- then 0.016-inch heat-activated nickel titanium arch wire during the alignment stage. - Effectiveness of the I-arch System | Not applicable | Recruiting | Tabark H. Omran | 34 | 2025-12-01 | 2026-04-22 |
| A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography Group A: Modified Miniscrew-Assisted Rapid Palatal Expander (MARPE), Group B: Modified Rapid Palatal Expander (RPE) - Malocclusion, Class I/II, Crowding | Not applicable | Active not recruiting | Al-Azhar University | 24 | 2025-11-01 | 2025-12-24 |
| A New Crowding Indicator in the Emergency Department Emergency Department, Crowding | Active not recruiting | Mario Negri Institute for Pharmacological Research | 828 | 2025-10-15 | 2026-05-20 | |
| Exploration of the Utility of Dental-dedicated MRI for Dentistry dental-dedicated MRI (ddMRI) - Dental Crowding, Dental Occlusion, Traumatic | Recruiting | University of Minnesota | 500 | 2025-03-17 | 2026-08-25 | |
| Length of Stay in Emergency Department: Impact of Anticipated Blood Sampling (LEIA) Anticipated blood sampling, No Anticipated Blood Sampling - Length of Stay, Blood Sampling | Completed | Centre Hospitalier de Roubaix | 28421 | 2025-01-01 | 2026-08-18 | |
| Birth Complications and Intrauterine Constraints in the Etiology of Congenital Muscular Torticollis: A Nationwide Registry Study Congenital Muscular Torticollis | Completed | Vestre Viken Hospital Trust | 7105 | 2024-11-26 | 2025-04-03 | |
| Hyrax Vs. Invisalign Palatal Expander Clinical Study Removable Rapid Palatal Expander, Banded Palatal Expander - Malocclusions, Narrow Maxilla | Not applicable | Recruiting | Align Technology, Inc. | 36 | 2024-10-25 | 2024-12-04 |
| Bone Level Changes Using Clear Aligners Compared to Fixed Appliances in Non-Extraction Treatment of Adults Fixed orthodontic appliance, Clear aligners - Dental Crowding, Alveolar Bone Loss | Not applicable | Completed | Future University in Egypt | 20 | 2024-08-15 | 2026-07-21 |
| Bracket Positioning Techniques and Quality of Orthodontic Finishing Smile Arc Protection (SAP) bracket positioning, Smile Arc and Marginal Ridge Approach (SAMRA) bracket positioning; Procedure, McLaughlin-Bennett-Trevisi (MBT) chart bracket positioning - Malocclusion, Angle Class I, Dental Crowding | Not applicable | Completed | Future University in Egypt | 39 | 2024-07-01 | 2026-07-16 |
| Evaluating the Clinical Efficacy of Collagen Scaffold (Ossix VOLUMAX) With Piezo-Surgical Decortication in Enhancing Orthodontic Treatment Outcomes: A Randomized Controlled Trial Piezocision with ribose cross-linked collagen matrix (Ossix® Volumax), control - Dental Crowding, Gingival Recession | Not applicable | Recruiting | NMSI DENTMASTER | 70 | 2024-06-25 | 2025-07-31 |
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Malocclusion (17) · Emergencies (8) · Malocclusion, Angle Class I (8) · Pain (4) · Amblyopia (2) · Periodontal Diseases (2) · Tooth Diseases (2) · Acute Disease (1) · Acute Kidney Injury (1) · Alveolar Bone Loss (1) · Anaphylaxis (1) · Ankle Injuries (1) · Anodontia (1) · Behavior (1)
Behavior (60) · Spatial Behavior (60) · Stomatognathic Diseases (25) · Tooth Diseases (23) · Pathological Conditions, Signs and Symptoms (13) · Pathologic Processes (9) · Disease Attributes (8) · Malocclusion (7) · Signs and Symptoms (7) · Neurologic Manifestations (6) · Mouth Diseases (5) · Nervous System Diseases (4) · Periodontal Diseases (3) · Wounds and Injuries (3) · Brain Diseases (2)
Orthodontic Appliances, Fixed (7) · Orthodontics (2) · Clinical Observation Units (1) · Donepezil (1) · Drug Interactions (1) · Low-Level Light Therapy (1) · Nasal Sprays (1) · Nicotine (1) · Observation (1) · Orthodontic Appliances, Removable (1) · Orthodontic Brackets (1) · Piezosurgery (1) · Tobacco Use Cessation Devices (1)
Damascus University (12) · Future University in Egypt (4) · University of Baghdad (3) · Al-Azhar University (2) · Cairo University (2) · Foundation University Islamabad (2) · 3D-Aligners (1) · Ahmed Talaat Hussein Ali (1) · Ain Shams University (1) · Align Technology, Inc. (1) · Anglia Ruskin University (1) · Ardentis Cliniques Dentaires (1) · Bezmialem Vakif University (1) · Centre Hospitalier de Roubaix (1) · Centre Hospitalier de Saint-Brieuc (1)
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Mohammad Y Hajeer, DDS MSc PhD (5) · Ahmad S Burhan, PhD. (3) · Mohammad Y Hajeer, DDS,MSc,PhD (3) · Samer T Jaber, DDS,MSc (2) · Abd Alrahman Qusaibati, DDS (1) · Abdulwahab Ahmed Alamri (1) · Ahmad S Burhan, DDS MSc PhD (1) · Ahmed T Ali, Demonstrator (1) · Bassel Brad, DDS MSc PhD (1) · Ching-Chang Ko, DDS, PhD (1) · Dennis M Levi, OD, PhD (1) · Dina AA Ragab, Ortho master (1) · Ewoud ter Avest, MD, PhD (1) · Giovanni Nattino (1)
PMID 10613941, PMID 10818378, PMID 15056110, PMID 1554175, PMID 16436790, PMID 17868386, PMID 18456146, PMID 18540011, PMID 18617108, PMID 18617110, PMID 20685517, PMID 21175021, PMID 22135148, PMID 22812378, PMID 23273363, PMID 23810039, PMID 23953094, PMID 24182579, PMID 24207160, PMID 24355870, PMID 25603272, PMID 25758457, PMID 26599124, PMID 26718375, PMID 26942200, PMID 27592083, PMID 27894540, PMID 28824369, PMID 29602338, PMID 30516419, PMID 30991984, PMID 33387908, PMID 34266842, PMID 35676524, PMID 37167078, PMID 37497386, PMID 37777351, PMID 38904564, PMID 39615435, PMID 40906653, PMID 42602182, PMID 7663253, PMID 8433468
2019 (1)