14 terminated. 14 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Terminated 14 |
| Phase 2 | 3 | Terminated 3 |
Follow Cross Infection: new trials by email Literature Review of Cross Infection trials Research Report on Cross Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2 Suvratoxumab, Placebo - Ventilator Associated Pneumonia, Staphylococcus Aureus | Phase 3 | Terminated | Aridis Pharmaceuticals, Inc. | 24 | 2022-09-02 | 2025-03-24 |
| Nebulized Aztreonam for Prevention of Gram Negative Ventilator-associated Pneumonia Aztreonam lysine, Aerogen Solo, CombiHaler - Ventilator Associated Pneumonia, Prevention | Phase 2 / Phase 3 | Terminated | Hospital Universitari Joan XXIII de Tarragona. | 9 | 2019-03-19 | 2021-07-01 |
| Nebulized and Intravenous Colistin in Ventilator Associated-pneumonia Intravenous colimycin, Intravenous placebo, Nebulized colimycin - Ventilator-associated Pneumonia | Phase 3 | Terminated | Assistance Publique - Hôpitaux de Paris | 7 | 2017-07-31 | 2018-08-13 |
| Aerosolized Plus Intravenous vs. Intravenous Colistin for VAP Due to Pandrugs-resistant A. Baumannii in Neonates Aerosolized plus intravenous colistin, Intravenous colistin - Pneumonia, Ventilator-Associated, Colistin Adverse Reaction | Phase 3 | Terminated | Hat Yai Medical Education Center | 204 | 2016-09-01 | 2018-08-02 |
| Study of Intravenous Ceftolozane/Tazobactam Compared to Piperacillin/Tazobactam in Ventilator-Associated Pneumonia Ceftolozane/Tazobactam, Piperacillin/Tazobactam - Ventilator-Associated Pneumonia (VAP) | Phase 3 | Terminated | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 4 | 2013-06-14 | 2018-11-16 |
| Daptomycin Versus Vancomycin in the Treatment of Nosocomial or Healthcare-associated MRSA Bacteremia vancomycin monotherapy, daptomycin monotherapy - Nosocomial Infection, Healthcare-associated Infection | Phase 3 | Terminated | Assistance Publique - Hôpitaux de Paris | 10 | 2012-05-01 | 2014-08-26 |
| Effect of Intermittent Versus Continuous Subglottic Secretion Drainage on Tracheal Mucosa Damages Intermittent subglottic secretion drainage, Continuous subglottic secretion drainage - Mechanical Ventilation Complication | Phase 3 | Terminated | Rennes University Hospital | 80 | 2011-08-01 | 2015-09-17 |
| A Safety and Tolerability Study of Doripenem Compared With Cefepime in Hospitalized Children With Bacterial Pneumonia Cefepime placebo, Cefepime, Doripenem - Pneumonia, Bacterial, Community-Acquired Infections | Phase 3 | Terminated | Janssen Research & Development, LLC | 7 | 2010-12-01 | 2014-07-15 |
| The Gravity-VAP (Ventilator-Associated Pneumonia) Trial lateral-Trendelenburg position - Ventilator Associated Pneumonia | Phase 3 | Terminated | Policlinico Hospital | 800 | 2010-11-01 | 2017-06-16 |
| Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis Daptomycin + Meropenem, Ceftazidime - Cirrhosis, Ascites | Phase 2 / Phase 3 | Terminated | University of Padova | 32 | 2010-10-01 | 2014-10-15 |
| Prophylactic Probiotics in Premature Infants Lactobacillus reuteri, Placebo - Death, Nosocomial Infection | Phase 3 | Terminated | Colombian Neonatal Research Network | 751 | 2008-08-01 | 2011-06-22 |
| Study of Povidone Iodine to Reduce Pulmonary Infection in Head Trauma and Cerebral Hemorrhage in Intensive Care Unit povidone iodine, Placebo - Ventilator Associated Pneumonia | Phase 3 | Terminated | Rennes University Hospital | 179 | 2008-04-01 | 2012-07-06 |
| To Compare Safety and Efficacy of Doripenem Versus Imipenem-Cilastatin in Patients With Ventilator-Associated Pneumonia Doripenem, Imipenem-Cilastatin, Placebo - Ventilator-Associated Pneumonia | Phase 3 | Terminated | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 274 | 2008-04-01 | 2012-12-28 |
| Trial of Iseganan in Prevention of Ventilator-Associated Pneumonia iseganan hydrochloride - Pneumonia | Phase 2 / Phase 3 | Terminated | IntraBiotics Pharmaceuticals | 900 | 2003-09-01 | 2005-07-19 |
Pneumonia, Ventilator-Associated (11) · Healthcare-Associated Pneumonia (2) · Ascites (1) · Bacteremia (1) · Community-Acquired Infections (1) · Community-Acquired Pneumonia (1) · Death (1) · Enterocolitis, Necrotizing (1) · Fibrosis (1) · Pneumonia (1) · Pneumonia, Bacterial (1) · Sepsis (1) · Staphylococcal Infections (1)
Disease Attributes (14) · Iatrogenic Disease (14) · Infections (14) · Pathologic Processes (14) · Pathological Conditions, Signs and Symptoms (14) · Lung Diseases (11) · Respiratory Tract Diseases (11) · Respiratory Tract Infections (11) · Pneumonia (10) · Healthcare-Associated Pneumonia (9) · Bacterial Infections (3) · Bacterial Infections and Mycoses (3) · Inflammation (2) · Systemic Inflammatory Response Syndrome (2)
Doripenem (2) · Amoxicillin-Potassium Clavulanate Combination (1) · Cefepime (1) · Ceftazidime (1) · Cilastatin, Imipenem Drug Combination (1) · Daptomycin (1) · Meropenem (1) · Piperacillin, Tazobactam Drug Combination (1) · Povidone-Iodine (1) · ceftolozane, tazobactam drug combination (1) · colistinmethanesulfonic acid (1) · suvratoxumab (1)
Assistance Publique - Hôpitaux de Paris (2) · Rennes University Hospital (2) · Aridis Pharmaceuticals, Inc. (1) · Colombian Neonatal Research Network (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · Hat Yai Medical Education Center (1) · Hospital Universitari Joan XXIII de Tarragona. (1) · IntraBiotics Pharmaceuticals (1) · Janssen Research & Development, LLC (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · Policlinico Hospital (1) · University of Padova (1)
France (6) · Spain (4) · United States (4) · Argentina (2) · Australia (2) · Belgium (2) · Brazil (2) · Colombia (2) · Israel (2) · Italy (2) · Mexico (2) · Thailand (2) · Ukraine (2) · Canada (1) · Germany (1)
Philippe Seguin, MD, PhD (2) · Bruno Laviolle, MD (1) · Bruno Laviolle, MD, PhD (1) · Juan M Lozano, MD, Msc (1) · Marin Kollef, MD (1) · Mario A Rojas, MD, MPH (1) · Narongsak Nakwan, MD (1) · Obiamiwe Umeh, MD (1) · Paolo Angeli, MD, PhD (1) · Qin LU, MD, PhD (1)
PMID 23071204, PMID 23148736, PMID 24105456, PMID 25050644, PMID 26472037, PMID 27080532, PMID 29041861, PMID 29149418, PMID 29422724, PMID 8888088
2009 (1), 2016 (1)