12 recruiting, 4 completed, 4 unknown, 3 enrolling by invitation. 6 Not applicable, 3 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Recruiting 3, Completed 1, Enrolling by invitation 1, Unknown 1 |
| Phase 4 | 3 | Not yet recruiting 2, Terminated 1 |
| Phase 1 | 1 | Withdrawn 1 |
Follow Coronary Artery Dissection, Spontaneous: new trials by email Literature Review of Coronary Artery Dissection, Spontaneous trials Research Report on Coronary Artery Dissection, Spontaneous
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Spontaneous Coronary Artery Dissection - AntipLatelet Therapy Intensity in Guided coNservative Management (SCAD-ALIGN) Trial Acetylsalicylic acid ASA, ASA plus Clopidogrel - SCAD, ACS (Acute Coronary Syndrome) | Phase 4 | Not yet recruiting | Universitätsklinikum Hamburg-Eppendorf | 3518 | 2027-03-01 | 2026-10-16 |
| Norwegian Danish Spontaneous Coronary Artery Dissection Exercise Study High intensity interval training (HIIT) - Spontaneous Coronary Artery Dissection, Myocardial Infarction (MI) | Not applicable | Enrolling by invitation | Oslo University Hospital | 120 | 2027-01-01 | 2026-08-25 |
| Spontaneous Coronary Artery Dissection (SCAD) Avatar Study Video Avatar Interview, Voice-Only Avatar Interview, Human Interview - Spontaneous Coronary Artery Dissection | Enrolling by invitation | Mayo Clinic | 150 | 2026-12-01 | 2026-09-23 | |
| A Study Of Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular Dysplasia Aerobic and resistance exercises - Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection | Not applicable | Recruiting | Mayo Clinic | 28 | 2026-09-01 | 2026-10-22 |
| Survey on Physical Activity and Qualify of Life in Fibromuscular Dysplasia Fibromuscular Dysplasia of Arteries, Fibromuscular Dysplasia | Recruiting | Vanderbilt University Medical Center | 2000 | 2026-04-14 | 2026-04-20 | |
| A Study of SCAD Using Stress Contrast Echocardiography Stress Echocardiography with Contrast - Spontaneous Coronary Artery Dissection | Recruiting | Mayo Clinic | 50 | 2025-11-25 | 2026-01-07 | |
| Exercise Support and Rehabilitation for Patients After Spontaneous Coronary Artery Dissection Exercise training - Spontaneous Coronary Artery Dissection | Not applicable | Recruiting | University of Leicester | 120 | 2025-05-01 | 2026-05-14 |
| Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics CMR - Myocardial Infarction With Non-Obstructive Coronary Artery, Myocarditis Acute | Not applicable | Unknown | University of Zurich | 75 | 2023-06-15 | 2024-03-21 |
| A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection Arterial Tonometry, Echocardiogram, Carotid Ultrasounds - Spontaneous Coronary Artery Dissection, Healthy | Not applicable | Recruiting | Mayo Clinic | 50 | 2023-06-01 | 2026-06-17 |
| Modalities And Safety Of Cardiac Rehabilitation In A Population Managed For Spontaneous Hematoma Or Coronary Disruption Data collection - Cardiac Rehabilitation Program Following the Management of ACS in Patients Presenting With SCAD | Unknown | University Hospital, Bordeaux | 90 | 2023-02-05 | 2023-03-01 | |
| Randomized Study of Beta-Blockers and Antiplatelets in Patients With Spontaneous Coronary Artery Dissection Beta blocker, aspirin, clopidogrel - Spontaneous Coronary Artery Dissection | Phase 4 | Not yet recruiting | Spanish Society of Cardiology | 600 | 2021-04-30 | 2021-04-20 |
| SCAD : a Registry of Spontaneous Coronary Artery Dissection There are no interventions as the study is purely observational. - Spontaneous Coronary Artery Dissection | Recruiting | European Society of Cardiology | 1500 | 2021-01-30 | 2024-10-29 | |
| Spontaneous Coronary Artery Dissection National Swiss Registry Spontaneous Coronary Artery Dissection | Recruiting | Dr. Sophie Degrauwe | 1000 | 2020-08-12 | 2022-11-16 | |
| International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry Spontaneous Coronary Artery Dissection | Active not recruiting | SCAD Alliance | 2000 | 2019-03-08 | 2026-05-06 | |
| Canadian SCAD Study Genetic sub-study - Spontaneous Coronary Artery Dissection, SCAD | Recruiting | Cardiology Research UBC | 3000 | 2018-12-01 | 2021-05-28 | |
| Using Ultrasonography, Shear Wave Elastography, Strain Imaging, and 3-D Volume Ultrasonography on Cardiovascular Disease Shear Wave Elastography, Pulse Wave Imaging, Contrast-Enhanced Ultrasound - Fibromuscular Dysplasia of Arteries, Segmental Arterial Mediolysis | Phase 1 | Withdrawn | Mayo Clinic | 2018-04-01 | 2020-05-29 | |
| Angiographic and Psychosocial Evaluation of Peripartum vs. Non: SCAD Spontaneous Coronary Artery Dissection | Completed | Katharine Sears Edwards | 241 | 2017-11-28 | 2019-09-25 | |
| Genetics of Spontaneous Coronary Artery Dissection (SCAD-INSPIRE Genetics) Spontaneous Coronary Artery Dissection | Enrolling by invitation | Intermountain Health Care, Inc. | 100 | 2016-10-17 | 2026-04-14 | |
| The Study of the Prevalence Fibromuscular Dysplasia in Patient With Haematoma or Spontaneous Coronary Artery Dissection. blood sample for genetic analysis - Spontaneous Coronary Artery Dissection, Spontaneous Coronary Artery Haematoma | Not applicable | Completed | University Hospital, Clermont-Ferrand | 200 | 2016-05-01 | 2026-08-03 |
| Spanish Registry on Spontaneous Coronary Artery Dissection Spontaneous Coronary Artery Dissection | Unknown | Spanish Society of Cardiology | 300 | 2015-01-01 | 2018-08-02 |
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Fibromuscular Dysplasia (6) · Myocardial Infarction (6) · Acute Coronary Syndrome (4) · Motor Activity (3) · MINOCA (2) · Addison Disease (1) · Anemia, Pernicious (1) · Angina Pectoris (1) · Antiphospholipid Syndrome (1) · Arthritis, Rheumatoid (1) · Celiac Disease (1) · Colitis, Ulcerative (1) · Coronary Artery Disease (1) · Crohn Disease (1)
Cardiovascular Diseases (16) · Vascular Diseases (16) · Heart Diseases (11) · Myocardial Ischemia (11) · Pathological Conditions, Signs and Symptoms (10) · Pathologic Processes (9) · Arterial Occlusive Diseases (7) · Infarction (7) · Ischemia (7) · Necrosis (7) · Behavior (3) · Adrenal Gland Diseases (1) · Adrenal Insufficiency (1) · Anemia (1) · Anemia, Macrocytic (1)
Aspirin (2) · Clopidogrel (2) · Adrenergic beta-Antagonists (1) · Blood Specimen Collection (1) · Contrast Media (1) · Data Collection (1) · Echocardiography (1) · Elasticity Imaging Techniques (1) · Exercise (1) · Genetic Testing (1) · High-Intensity Interval Training (1) · Ramipril (1) · Rosuvastatin Calcium (1) · Ultrasonography, Carotid Arteries (1)
Mayo Clinic (8) · Cardiology Research UBC (3) · Spanish Society of Cardiology (2) · Dr. Sophie Degrauwe (1) · European Society of Cardiology (1) · Hospital Israelita Albert Einstein (1) · Icahn School of Medicine at Mount Sinai (1) · Intermountain Health Care, Inc. (1) · Katharine Sears Edwards (1) · Oslo University Hospital (1) · SCAD Alliance (1) · San Luigi Gonzaga Hospital (1) · University Hospital, Bordeaux (1) · University Hospital, Clermont-Ferrand (1) · University of Leicester (1)
United States (13) · Canada (4) · France (3) · United Kingdom (3) · Brazil (2) · Germany (2) · Netherlands (2) · Norway (2) · Spain (2) · Switzerland (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · Bosnia and Herzegovina (1)
Jacqueline Saw, MD (2) · Aaron W Aday, MD, MSc (1) · Adriano Caixeta, MD, PhD (1) · David Adlam, BA BM BCh DPhil FRCP FESC (1) · Elizabeth H. Dineen, DO (1) · Enrico Cerrato, MD (1) · Esther Kim, MD (1) · Jamil Cade, MD, PhD (1) · Jason Kovacic, MD, PhD (1) · Jeffrey Olin, DO (1) · Jennifer Ann Tremmel, MD, MS (1) · Katharine S. Edwards, PhD (1) · Kristina Hermann Haugaa, Phd (1) · Malissa Wood, MD (1)
PMID 30621952, PMID 25798899, PMID 26928981, PMID 27792790, PMID 30561271, PMID 30698711, PMID 30888838, PMID 31424497, PMID 32374345, PMID 32418854, PMID 32531060, PMID 33617813, PMID 33620451, PMID 33878074, PMID 34338759, PMID 34384238, PMID 34561195, PMID 35410894, PMID 36244863, PMID 37248441, PMID 37259861, PMID 38533943, PMID 42199296
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