838 completed, 273 unknown, 131 recruiting, 77 terminated. 677 Not applicable, 107 Phase 4, 103 Phase 2, 79 Phase 3, 64 Phase 1.
Follow this condition Literature Review of COPD trials Research Report on COPD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RSV Vaccination to Reduce Recurrent AECOPD RSV vaccination (Arexvy, GlaxoSmithKline) - COPD, RSV | Phase 4 | Not yet recruiting | Chinese University of Hong Kong | 320 | 2027-07-01 | 2026-04-13 |
| Pulmonary Rehabilitation Frequency in COPD Patients Pulmonary Rehabilitation - COPD, COPD (Chronic Obstructive Pulmonary Disease) | Not applicable | Not yet recruiting | Hospital Universitario Fundación Alcorcón | 158 | 2027-01-01 | 2026-05-08 |
| Portable Positive Pressure Therapy Device BREATHE, BiPAP, COPD Inhaler - COPD | Not applicable | Not yet recruiting | Koronis Biomedical Technologies | 20 | 2026-12-01 | 2025-03-25 |
| Effect on Bronchodilation Response and Ventilation Heterogeneity of Different Inhalation Volumes in COPD Inhalation of bronchodilation therapy at FRC, Inhalation of bronchodilation therapy at RV - COPD, Lung Injury | Not yet recruiting | University of Milan | 30 | 2026-12-01 | 2026-05-04 | |
| Feasibility of Noninvasive Trigeminal Nerve Stimulation During Exercise Active Stimulation, Sham Stimulation, Fan therapy - COPD | Not applicable | Not yet recruiting | Johns Hopkins University | 40 | 2026-11-01 | 2026-10-14 |
| Evaluating Customized Antibiotic Duration (CDA) Strategy in Acute Exacerbations of COPD 7-day antibiotic course, 14-day antibiotic course - COPD, Acute Exacerbation of COPD | Not applicable | Not yet recruiting | Capital Development Authority (CDA) | 560 | 2026-10-26 | 2026-10-07 |
| THERMotherapy Against Persistent Bacterial LUNG Infections Thermotherapy/sauna bath - Lung Diseases, Obstructive, Bronchiectasis | Not applicable | Not yet recruiting | Chronic Obstructive Pulmonary Disease Trial Network, Denmark | 150 | 2026-10-01 | 2026-06-17 |
| Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation Progressive Walking Exercise Programme, Real-time air quality information and guidance - Cardiovascular Disease, Asthma | Not applicable | Not yet recruiting | University of Leicester | 80 | 2026-10-01 | 2026-10-05 |
| The CANadian EXAcerbation of COPD Trial COPD, AECOPD | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 125 | 2026-09-28 | 2026-10-05 | |
| A COPD Data Registry for Participants With Frequent Exacerbations COPD | Withdrawn | Hoffmann-La Roche | 2026-09-14 | 2026-06-22 | ||
| HFNC During Bronchoscopy in COPD Patients group N used traditional nasal cannula for oxygen inhalation, Group HFNC used nasal high-flow oxygen inhalation. - COPD | Not applicable | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 1000 | 2026-09-01 | 2026-09-30 |
| Immuno-inflammatory Response of Erdosteine in COPD Erdosteine, Standard of Care (SOC) - COPD | Not applicable | Not yet recruiting | Pierachille Santus, MD, PhD | 30 | 2026-09-01 | 2026-04-29 |
| GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD Tirzepatide - COPD, Obesity & Overweight | Phase 2 | Not yet recruiting | The Cleveland Clinic | 30 | 2026-08-28 | 2026-08-05 |
| The Feasibility of Electrical Impedance Tomography to Guide Non-invasive Respiratory Interventions in Chronic Respiratory Disease electrical impedance tomography - COPD, Non Invasive Ventilation (NIV) | Enrolling by invitation | Royal Free Hospital NHS Foundation Trust | 20 | 2026-08-27 | 2026-09-09 | |
| Cognitive Load and Inhaler Technique in COPD Working-Memory Cognitive Load During Inhaler Use, Single-Task Inhaler Use - COPD | Not applicable | Recruiting | Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara | 100 | 2026-08-21 | 2026-08-26 |
| Outpatient Rehabilitation Programmes for Myocardial Ischemia, Heart Failure, and COPD: Satisfaction, Participation, Test Outcomes, and Factors Associated With Positive Changes in Test Results as Well as Level of Participation Heart Disease, COPD | Not yet recruiting | Nordsjaellands Hospital | 840 | 2026-08-01 | 2026-05-19 | |
| A Study to Evaluate the Diagnostic Performance of Portable Oscillometry Across Chronic Respiratory Diseases COPD, Asthma (Diagnosis) | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 4000 | 2026-07-30 | 2026-06-08 | |
| A Clinical Trial to Evaluate the Efficacy and Safety of HRS-9821 Inhalation Suspension in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease HRS-9821 Inhalation Suspension, HRS-9821 Placebo Inhalation Suspension - COPD | Phase 2 | Recruiting | Guangdong Hengrui Pharmaceutical Co., Ltd | 90 | 2026-07-20 | 2026-08-18 |
| PEP Buddy in Pulmonary Rehabilitation PEP Buddy, PEP Buddy Sham - COPD | Not applicable | Recruiting | VA Office of Research and Development | 120 | 2026-07-16 | 2026-07-24 |
| Effects of Adapted Snacktivity™ Intervention on Cognition and Self-Care in COPD Patients Snacktivity™ Intervention, attention control - COPD, Physical Activity | Not applicable | Not yet recruiting | The University of Hong Kong | 210 | 2026-07-15 | 2026-07-14 |
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Pulmonary Disease, Chronic Obstructive (1472) · Asthma (155) · Dyspnea (85) · Emphysema (81) · Motor Activity (71) · Lung Diseases (50) · Heart Failure (49) · Bronchitis, Chronic (45) · Smoking (34) · Lung Diseases, Interstitial (30) · Anxiety Disorders (28) · Diabetes Mellitus (28) · Pneumonia (27) · Respiratory Insufficiency (26) · Lung Neoplasms (24)
Disease Attributes (1472) · Pathological Conditions, Signs and Symptoms (1472) · Pathologic Processes (1471) · Chronic Disease (1466) · Respiratory Tract Diseases (1455) · Lung Diseases, Obstructive (1454) · Lung Diseases (1422) · Bronchial Diseases (210) · Behavior (165) · Immune System Diseases (164) · Signs and Symptoms (162) · Hypersensitivity (155) · Hypersensitivity, Immediate (155) · Respiratory Hypersensitivity (155) · Respiration Disorders (148)
Formoterol Fumarate (36) · Tiotropium Bromide (36) · Exercise (29) · Albuterol (16) · Glycopyrrolate (16) · indacaterol (16) · Noninvasive Ventilation (15) · Roflumilast (14) · Budesonide (11) · Educational Status (11) · Oxygen (10) · Salmeterol Xinafoate (10) · Standard of Care (10) · Beclomethasone (9) · Fluticasone (9)
AstraZeneca (34) · Riphah International University (26) · Imperial College London (19) · Assiut University (15) · Chiesi Farmaceutici S.p.A. (15) · Pearl Therapeutics, Inc. (14) · University Medical Center Groningen (14) · Novartis Pharmaceuticals (12) · VA Office of Research and Development (12) · McGill University Health Centre/Research Institute of the McGill University Health Centre (11) · The First Affiliated Hospital of Guangzhou Medical University (11) · Weill Medical College of Cornell University (11) · Izmir Katip Celebi University (10) · Johns Hopkins University (10) · Schön Klinik Berchtesgadener Land (10)
United States (337) · United Kingdom (141) · France (82) · Turkey (Türkiye) (80) · Germany (78) · Canada (77) · China (77) · Italy (68) · Denmark (57) · Spain (55) · Netherlands (49) · Belgium (40) · Taiwan (35) · Sweden (31) · Pakistan (30)
Ronald G Crystal, MD (9) · Denis E O'Donnell, MD, FRCPC (5) · Klaus Kenn, Prof. Dr. (5) · Roberto P Benzo (5) · Colin Reisner, MD (4) · Louise E Donnelly, PhD (4) · Marilyn L. Moy, MD (4) · Martyn R Partridge, MD FRCP (4) · Michele Vitacca, MD (4) · Narongkorn Saiphoklang, MD (4) · Arthur F Gelb, MD (3) · Cecil Charles, PhD (3) · Chadwick Orevillo (3)
PMID 33511633, PMID 17951621, PMID 24127811, PMID 25359355, PMID 25918120, PMID 35815359, PMID 11282762, PMID 16310554, PMID 16936234, PMID 17197484, PMID 1759018, PMID 18786894, PMID 20071991, PMID 21103404, PMID 24787074, PMID 24845559, PMID 25866645, PMID 25981908, PMID 26797036, PMID 33152467, PMID 9789243, PMID 10377201, PMID 11019457, PMID 12091180, PMID 15764761, PMID 1576849, PMID 16322646, PMID 16565429, PMID 16799080, PMID 17310045, PMID 17443585, PMID 17765528, PMID 18625750, PMID 19467849, PMID 19720809, PMID 21172990, PMID 21272339, PMID 21310878, PMID 21367593, PMID 21385216, PMID 22878278, PMID 23446173, PMID 24430178, PMID 25338316, PMID 25430600, PMID 25742321, PMID 27060726, PMID 27578482, PMID 28419462, PMID 28821260
2018 (6), 2025 (5), 2019 (4), 2008 (3), 2015 (3), 2023 (2), 1IK2RX003535 (1), 2009 (1), 2016 (1), 3UH3CA233314-02S1 (1), I01CX002686 (1), I01RD000440 (1), I01RX002855 (1), K23HL141651 (1), K23HL146946 (1)