41 completed, 13 unknown, 7 recruiting, 2 terminated. 14 Not applicable, 4 Phase 1, 3 Phase 3, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 10, Unknown 3, Terminated 1 |
| Phase 1 | 4 | Completed 4 |
| Phase 3 | 3 | Recruiting 2, Unknown 1 |
| Phase 4 | 2 | Recruiting 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Coagulation Disorder: new trials by email Literature Review of Coagulation Disorder trials Research Report on Coagulation Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 Trial of Reltodecacog Alfa (VMX-C001) vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin. Reltodecacog alfa, Usual Pharmacological Care - Blood Loss, Surgical, Coagulation Disorder | Phase 3 | Recruiting | VarmX B.V. | 800 | 2026-08-18 | 2026-10-14 |
| Effects of Lipid Emulsions on Coagulation Lipid Emulsion - Coagulation Disorder, Coagulation Function | Completed | Mimi Tang, PhD | 6259 | 2025-05-23 | 2026-03-13 | |
| Effects of VMX-C001 on the Anticoagulant Effect of Different Forms of Heparin VMX-C001, Rivaroxaban, UFH - Coagulation Disorder | Phase 1 | Completed | VarmX B.V. | 16 | 2024-08-14 | 2026-05-11 |
| SWIFT - SWIss Factor XIII Trial in PPH Fibrogammin - Postpartum Hemorrhage, Coagulation Disorder | Phase 4 | Recruiting | Christian Haslinger | 988 | 2024-07-09 | 2026-04-27 |
| Single Dose Trial of VMX-C001 in Healthy Subjects With and Without FXa Direct Oral Anticoagulant VMX-C001, Placebo, Rivaroxaban 20 mg Oral Tablet - Coagulation Disorder | Phase 1 | Completed | VarmX B.V. | 40 | 2024-02-21 | 2026-09-09 |
| The ENDOCARDITIS AUMC Data Collection None, observational - Endocarditis, Coagulation Disorder | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 3000 | 2023-08-06 | 2023-07-25 | |
| Blood Coagulation Profile After Liver Resection. thromboelastography (TEG®6s) - Coagulation Disorder | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 46 | 2023-04-12 | 2024-01-25 | |
| Heparin Reversal With Two Different Protamine Ratios After Cardiopulmonary By-pass. Protamin - Cardiac Surgery, CAD | Not applicable | Completed | University of Ioannina | 98 | 2023-03-18 | 2024-05-31 |
| Coagulation in Acute Aortic Dissection Individualized HDR-approach, Conventional ACT-approach - Acute Aortic Dissection, Coagulation Disorder | Not applicable | Completed | Ivy susanne Modrau, MD | 26 | 2022-11-01 | 2025-07-18 |
| A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery TAK-330, SOC 4F-PCC - Coagulation Disorder | Phase 3 | Recruiting | Takeda | 440 | 2022-08-24 | 2026-06-18 |
| Thrombin in Cardiac Surgery Thrombin, Hemostatic Disorder | Unknown | University Health Network, Toronto | 200 | 2022-08-10 | 2022-11-09 | |
| The Impact of Coagulation Disorders on the Diagnosis and Prognosis of Sepsis Early general coagulation function (5 items of coagulation) and thromboelastogram monitoring - Sepsis, Coagulation Disorder | Unknown | Ruijin Hospital | 552 | 2022-06-01 | 2023-08-21 | |
| The Acute Effects of Chamomile Intake on Blood Coagulation Tests in Healthy Volunteers Chamomile Tea, Chamomile Extract Capsule - Coagulation Disorder | Not applicable | Completed | Stony Brook University | 8 | 2022-03-16 | 2022-06-10 |
| Subclinical Impairment of Cardiovascular System in Patients With Psoriasis Psoriasis, Inflammation | Completed | University Medical Centre Ljubljana | 100 | 2022-01-03 | 2023-07-24 | |
| Study of Intravenous VMX-C001 in Healthy Subjects and in Combination With Selected Direct Oral Anticoagulants in Healthy Older Subjects VMX-C001, Placebo, Apixaban - Coagulation Disorder | Phase 1 | Completed | VarmX B.V. | 105 | 2021-10-29 | 2023-06-02 |
| Extracellular Vesicles and Dysregulated Coagulation in the Prediction of Stroke Stroke, Ischemic, Transient Ischemic Attack | Recruiting | Cwm Taf University Health Board (NHS) | 360 | 2021-10-01 | 2024-08-20 | |
| Effect of Chamomile Intake on Blood Coagulation Tests in Healthy Volunteers Chamomile Tea, Chamomile Extract Capsule, Placebo Capsule - Coagulation Disorder | Not applicable | Completed | Stony Brook University | 12 | 2021-08-31 | 2022-02-10 |
| Rifaximin in Cirrhosis: Effects on Endotoxin and Haemostatic Indexes Rifaximin, Placebo - Liver Cirrhosis, Coagulation Disorder | Phase 4 | Terminated | University of Roma La Sapienza | 20 | 2021-04-03 | 2024-10-08 |
| Coagulation Disturbances in COVID-19 Septic Patients CAC in septic patients - Coagulation Disorder, COVID 19 Associated Coagulopathy | Completed | Cantonal Hospital Zenica | 100 | 2021-01-01 | 2022-08-11 | |
| Blood Loss and Preeclampsia Blood sample - Pre-Eclampsia; Complicating Pregnancy, Blood Loss | Unknown | University of Zurich | 120 | 2021-01-01 | 2023-12-05 |
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Hemostatic Disorders (63) · Thrombosis (9) · Hemorrhage (7) · COVID-19 (6) · Brain Injuries, Traumatic (5) · Blood Loss, Surgical (4) · Liver Cirrhosis (4) · Anemia (3) · Ischemic Stroke (3) · Pneumonia (3) · Thrombocytopenia (3) · Acute Kidney Injury (2) · Blood Platelet Disorders (2) · Coronary Artery Disease (2) · Disseminated Intravascular Coagulation (2)
Cardiovascular Diseases (63) · Hemic and Lymphatic Diseases (63) · Hemorrhagic Disorders (63) · Vascular Diseases (63) · Hematologic Diseases (61) · Pathologic Processes (21) · Pathological Conditions, Signs and Symptoms (21) · Embolism and Thrombosis (11) · Nervous System Diseases (11) · Brain Diseases (9) · Central Nervous System Diseases (9) · Infections (9) · Wounds and Injuries (9) · Female Urogenital Diseases and Pregnancy Complications (8) · Urogenital Diseases (8)
Enoxaparin (3) · Rivaroxaban (3) · Thrombelastography (3) · apixaban (3) · Blood Specimen Collection (2) · Chamomile extract (2) · edoxaban (2) · 2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine (1) · Abatacept (1) · Albuterol (1) · Aminocaproic Acid (1) · Amiodarone (1) · Anesthesia, General (1) · Aspirin (1) · Azithromycin (1)
HemoSonics LLC (4) · VarmX B.V. (4) · Abbott Medical Devices (2) · Hospitales Universitarios Virgen del Rocío (2) · Stony Brook University (2) · Tang-Du Hospital (2) · AHEPA University Hospital (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Assiut University (1) · Ataturk University (1) · Augusta University (1) · Azienda Ospedaliero-Universitaria di Modena (1) · Cairo University (1) · Cantonal Hospital Zenica (1) · Centre Antoine Lacassagne (1)
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