4 completed, 3 recruiting, 3 unknown, 2 terminated. 16 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Completed 4, Recruiting 3, Unknown 3, Terminated 2, Withdrawn 2, Enrolling by invitation 1, Not yet recruiting 1 |
Follow Chorioamnionitis: new trials by email Literature Review of Chorioamnionitis trials Research Report on Chorioamnionitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Amnioinfusion for Chorioamnionitis: Targeting Neonatal Brain Injury Biomarkers Intrauterine Pressure Catheter, Standard obstetric care at discretion of delivery provider - Chorioamnionitis Affecting Fetus or Newborn, Amnioinfusion | Not applicable | Recruiting | Medical College of Wisconsin | 80 | 2026-10-15 | 2026-10-26 |
| Planned Early Induction of Labor vs Expectant Management for PROM Induction of labor with PGE2, Expectant management - Premature Rupture of Membranes (PROM) | Not applicable | Enrolling by invitation | Pakistan Institute of Medical Sciences | 734 | 2026-05-01 | 2026-09-03 |
| Preterm Rupture of Membranes Optimising Antibiotics Trial Erythromycin 250mg + placebo, Azithromycin 500mg + placebo, Erythromycin 250mg and Amoxicillin 500mg - PPROM, Preterm | Not applicable | Not yet recruiting | University of Melbourne | 3900 | 2025-09-01 | 2025-04-02 |
| Comparing Infectious Morbidity Among Women With Meconium-stained Amniotic Fluid at Term, Between Those Treated With Prophylactic Antibiotics Zinacef vs. Placebo zinacef tretment, Placebo - Meconium-stained Amniotic Fluid, Chorioamnionitis | Not applicable | Recruiting | Western Galilee Hospital-Nahariya | 182 | 2025-02-18 | 2026-09-15 |
| Intrapartum Ultrasound in Labor: Sonography Only, Few Internal Examinations Sonography in labour - Labor Complication | Not applicable | Recruiting | Larry Hinkson | 356 | 2024-02-27 | 2024-02-16 |
| Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term Cervical examination to assess labor - Chorioamnionitis, Intrauterine Infection | Not applicable | Terminated | Eastern Virginia Medical School | 163 | 2021-09-02 | 2023-08-25 |
| Management of Prelabor Rupture of the Membranes at Term Oxytocin - Fetal Infection, Chorioamnionitis | Not applicable | Unknown | Rambam Health Care Campus | 524 | 2020-05-01 | 2024-04-12 |
| Assessment of Labour Progress by Intrapartum Ultrasound Transperineal Ultrasound - Pregnancy Related, Fever | Not applicable | Completed | Kaplan Medical Center | 180 | 2019-08-27 | 2020-12-03 |
| Chorioamnionitis: Observation of at Risk Infants vs Standard Care Clinical observation, Standard management - Chorioamnionitis, Early Onset Neonatal Sepsis | Not applicable | Withdrawn | IRCCS Burlo Garofolo | 2016-10-01 | 2019-07-12 | |
| Closure of Skin in ChorioAmnionitis Research Pilot Study Suture closure, Staples closure - Chorioamnionitis, Pregnancy Complications, Infectious | Not applicable | Unknown | University of British Columbia | 60 | 2014-02-01 | 2017-05-12 |
| Immediate Versus Delayed Induction in Term-PROM Using or Not Antibiotic Prophylaxis Cefoxitin, oxytocin/misoprostol - Maternal Infection During Pregnancy (Diagnosis), Neonatal Infection | Not applicable | Unknown | Hospital de Santa Maria, Portugal | 568 | 2013-07-01 | 2016-12-13 |
| Maternal Plasmatic Regulatory T Cells and Th17 as Possible Diagnosis Markers of Acute Chorioamnionitis Blood and placenta samples - Pathology of Pregnancy | Not applicable | Completed | Centre Hospitalier Universitaire Dijon | 95 | 2013-03-26 | 2024-02-22 |
| Intrapartum Study of Sterile and Clean Gloves Type of glove used for intrapartum vaginal exams - Chorioamnionitis | Not applicable | Completed | Medical University of South Carolina | 507 | 2011-05-01 | 2018-05-18 |
| Treatment of Chorioamnionitis After Delivery saline, ampicillin gentamicin, Ampicillin gentamicin clindamycin - Chorioamnionitis | Not applicable | Withdrawn | United States Naval Medical Center, Portsmouth | 2008-11-18 | 2025-08-03 | |
| Safety and Efficacy Study of Intentional Delivery in Women With Preterm and Prelabour Rupture of the Membranes Induction of delivery - Fetal Membranes, Premature Rupture | Not applicable | Terminated | University of Alberta | 152 | 2006-01-01 | 2020-03-25 |
| Comparison of Once Daily Versus 8 Hour Dosing of Gentamicin for the Treatment of Intrapartum Chorioamnionitis gentamicin - Chorioamnionitis | Not applicable | Completed | Stanford University | 126 | 2004-06-01 | 2011-06-15 |
Fetal Membranes, Premature Rupture (3) · Endometritis (2) · Neonatal Sepsis (2) · Obstetric Labor Complications (2) · Premature Birth (2) · Preterm Premature Rupture of the Membranes (2) · Disease (1) · Fever (1) · Postoperative Complications (1) · Pregnancy Complications, Infectious (1) · Puerperal Infection (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (16) · Female Urogenital Diseases and Pregnancy Complications (16) · Fetal Diseases (16) · Placenta Diseases (16) · Pregnancy Complications (16) · Urogenital Diseases (16) · Obstetric Labor Complications (14) · Fetal Membranes, Premature Rupture (13) · Pathological Conditions, Signs and Symptoms (5) · Infections (4) · Pathologic Processes (4) · Adnexal Diseases (2) · Female Urogenital Diseases (2) · Genital Diseases (2) · Genital Diseases, Female (2)
Oxytocin (2) · Watchful Waiting (2) · Amoxicillin (1) · Azithromycin (1) · Blood Specimen Collection (1) · Cefoxitin (1) · Dinoprostone (1) · Erythromycin (1) · Gentamicins (1) · High-Energy Shock Waves (1) · Labor, Induced (1) · Misoprostol (1) · Sodium Chloride (1) · Sutures (1)
Centre Hospitalier Universitaire Dijon (1) · Eastern Virginia Medical School (1) · Hospital de Santa Maria, Portugal (1) · IRCCS Burlo Garofolo (1) · Kaplan Medical Center (1) · Larry Hinkson (1) · Medical College of Wisconsin (1) · Medical University of South Carolina (1) · Pakistan Institute of Medical Sciences (1) · Rambam Health Care Campus (1) · Stanford University (1) · United States Naval Medical Center, Portsmouth (1) · University of Alberta (1) · University of British Columbia (1) · University of Melbourne (1)
United States (5) · Israel (3) · Canada (2) · France (1) · Germany (1) · Italy (1) · Pakistan (1) · Portugal (1)
Clare Whitehead, MBChB, PhD (1) · Donna Johnson (1) · Ellen M Giesbrecht, MD (1) · Everett F Magann, MD (1) · Gal Bachar, MD (1) · Jennifer A Hutcheon, PhD (1) · Julie E van Schalkwyk, MD (1) · Larry Hinkson, FRCOG (1) · Laura Houston, MD (1) · Maya Oberman, MD (1) · Michael WH Suen, MD (1) · Radha Chari, MD,FRCPC (1) · Sergio Demarini, MD (1) · Stacy Slat, MD (1) · Thierry Lacaze-Masmonteil, MD, PhD (1)
PMID 11181139, PMID 15295368, PMID 20093909, PMID 21251190, PMID 22617572, PMID 27974410, PMID 28454555, PMID 28742677, PMID 32334543, PMID 36396038, PMID 36400420, PMID 36965695