48 completed, 20 unknown, 5 terminated, 2 recruiting. 31 Not applicable, 22 Phase 4, 16 Phase 3, 9 Phase 2, 1 Phase 1.
Follow Dinoprostone: new trials by email Literature Review of Dinoprostone trials Research Report on Dinoprostone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Planned Early Induction of Labor vs Expectant Management for PROM Induction of labor with PGE2, Expectant management - Premature Rupture of Membranes (PROM) | Not applicable | Enrolling by invitation | Pakistan Institute of Medical Sciences | 734 | 2026-05-01 | 2026-09-03 |
| PGE2 Followed by Oxytocin vs Oxytocin in Term PROM (POXY-PROM) Sequential Induction: Dinoprostone Followed by Oxytocin, Immediate Oxytocin Induction - Premature Rupture of Fetal Membranes, Labor, Induced | Not applicable | Recruiting | National Hospital of Obstetrics and Gynecology | 450 | 2026-02-10 | 2026-02-20 |
| Comparison of Vaginal PGE2 (Dinoprostone) and Vaginal Misoprostol for Induction of Labour in Primigravid Term Pregnancy Misoprostol, Dinoprostone 3 mg - Labor, Induced, Term Pregnancy | Not applicable | Active not recruiting | Mayo Hospital Lahore | 240 | 2025-10-29 | 2026-04-30 |
| Membrane Stripping for Cervical Ripening Double Baloon Catheter, Membrane Stripping, PGE2 - Labor, Induced, Cervical Ripening | Not applicable | Recruiting | Meir Medical Center | 400 | 2024-08-07 | 2026-04-15 |
| Foley Catheter Versus PGE2 for Labor Induction at Term: a Pilot Study Induction of labor with Foley catheter, Induction of labor with PGE2 - Labor Induction, Induced Delivery | Phase 4 | Suspended | Guangzhou Women and Children's Medical Center | 200 | 2023-12-01 | 2023-09-15 |
| Misoprostol Versus Dinoprostone in Induction of Labor Misoprostol - Induction of Labor | Not applicable | Completed | Al-Azhar University | 200 | 2023-06-10 | 2025-04-03 |
| Outpatient Induction of Labour Using Intracervical Foley Catheter Foley catheter, Intravaginal prostaglandin E2 - Pregnancy Related, Induction of Labor Affected Fetus / Newborn | Not applicable | Terminated | Hospital Kemaman | 88 | 2023-01-01 | 2025-01-17 |
| Gemeprost Versus Dinoprostone in First Trimester Miscarriages Gemeprost 1 Mg Vaginal Pessary, Dinoprostone 3 mg - Missed Abortion, Medical; Abortion, Fetus | Phase 2 | Completed | National University of Malaysia | 101 | 2022-11-11 | 2025-06-11 |
| Dinoprostone Induction vs. Expectant Management After PROM at Term Dinoprostone - Prelabor Rupture of Membranes | Phase 4 | Unknown | University Medical Centre Ljubljana | 70 | 2022-06-01 | 2022-06-24 |
| DOuble-BAlloon Versus PROstaglandin E2 for Cervical Ripening in Low Risk Pregnancies Double-balloon catheter (UTAH CVX-RIPE) for cervical ripening, Dinoprostone 10mg (Propess) - Induction of Labor | Not applicable | Unknown | Hanoi Obstetrics and Gynecology Hospital | 540 | 2021-08-01 | 2024-03-01 |
| Propess Versus Prostin for Induction of Labour in Women With Term PROM Prostaglandin E2 (Propess), Prostaglandin E2 (Prostin) - Premature Rupture of Membranes at Term, Induction of Labour | Phase 4 | Unknown | University Medical Centre Maribor | 526 | 2021-03-01 | 2021-02-15 |
| Labor Induction After Failed Induction With Dinoprostone. Dinoprostone, Cervical ripening balloon. - Induction of Labor Affected Fetus / Newborn | Not applicable | Completed | Rambam Health Care Campus | 144 | 2020-10-15 | 2022-04-20 |
| Vaginal Dinoprostone Versus Isonicotinic Acid Hydrazide Prior to Diagnostic Office Hysteroscopy INH, dinoprostone - Postmenopausal Bleeding | Not applicable | Unknown | Aswan University Hospital | 200 | 2020-09-01 | 2021-09-29 |
| Diclofenac Potassium With or Without Vaginal Dinoprostone Prior to Hysterosalpingography diclofenac potassium + dinoprostone, diclofenac potassium + placebo - Infertility, Female | Not applicable | Completed | Aswan University Hospital | 200 | 2020-09-01 | 2022-01-19 |
| Modality of Induction of Labor in Obese Women at Term (MODOBAT) Dinoprostone 10mg, single balloon Foley catheter - Induction of Labor Affected Fetus / Newborn, Obese | Completed | Centre Hospitalier Universitaire de Besancon | 77 | 2020-06-11 | 2021-05-03 | |
| Single-dose Vaginal Dinoprostone and Hysterectomy Dinoprostone 3 mg, placebo - Hysterectomy | Phase 3 | Completed | Cairo University | 118 | 2019-09-25 | 2020-08-27 |
| Vaginal Dinoprostone Administration Prior to Intrauterine Device Insertion Dinoprostone, placebo - IUD Insertion Pain | Phase 4 | Completed | Cairo University | 130 | 2019-09-15 | 2020-07-31 |
| Comparison of Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Women Delivered Only by Cesarean Delivery Dinoprostone 3 mg, Misoprostol 200Mcg Tab, placebo - IUD Pain | Phase 4 | Unknown | Cairo University | 300 | 2019-09-10 | 2019-09-06 |
| Preoperative Vaginal Dinoprostone Prior to Abdominal Myomectomy Dinoprostone 3 mg, placebo - Myomectomy | Phase 3 | Unknown | Cairo University | 100 | 2019-09-10 | 2019-09-06 |
| Comparison of Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Nulliparous Women Dinoprostone, Misoprostol, placebo - IUD Insertion Complication | Phase 4 | Completed | Cairo University | 129 | 2019-09-10 | 2020-06-30 |
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Fetal Membranes, Premature Rupture (7) · Obesity (2) · Abortion, Incomplete (1) · Abortion, Missed (1) · Abortion, Spontaneous (1) · Chorioamnionitis (1) · Fetal Death (1) · Genital Diseases, Female (1) · Headache (1) · Infertility, Female (1) · Labor Pain (1) · Migraine Disorders (1) · Muscular Dystrophy, Duchenne (1) · Myofibroma (1) · Pre-Eclampsia (1)
Cairo University (10) · Ferring Pharmaceuticals (5) · Seoul National University Hospital (4) · Ain Shams University (3) · Rambam Health Care Campus (3) · Aswan University Hospital (2) · Nilratan Sircar Medical College (2) · Zeynep Kamil Maternity and Pediatric Research and Training Hospital (2) · Ain Shams Maternity Hospital (1) · Al-Azhar University (1) · Aljazeera Hospital (1) · Ankara University (1) · Beni-Suef University (1) · Birmingham Women's NHS Foundation Trust (1) · Centre Hospitalier Departemental Vendee (1)
Egypt (17) · France (6) · United States (6) · Israel (5) · Turkey (Türkiye) (5) · South Korea (4) · United Kingdom (3) · Brazil (2) · Canada (2) · Denmark (2) · India (2) · Italy (2) · Japan (2) · Malaysia (2) · Pakistan (2)
Kyo Hoon Park, MD, PhD (3) · Acar F Koc, Professor (1) · Ahmed Abdelaziz, M.D. (1) · Ahmed S. Abd El-Hamid, Doctorate (1) · Amir Weissman, MD (1) · Amr H Farag, Consultant (1) · Amr H Yehia, MD, MRCOG (1) · Anh Nguyen Duy, PhD. MD (1) · Anne ML Berndl, MD MSc (1) · B A Armson, MD MSc FRCSC (1) · Ben W Mol, PhD. MD (1)
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