109 completed, 44 recruiting, 34 unknown, 15 not yet recruiting. 110 Not applicable, 31 Phase 3, 25 Phase 2, 16 Phase 4, 12 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tranexamic Acid to Reduce Blood Loss After Varus Derotation Osteotomy Tranexamic Acid (IV), Placebo - Cerebral Palsy, Hip Surgery Corrective | Phase 3 | Not yet recruiting | Murdoch Childrens Research Institute | 52 | 2026-11-01 | 2026-10-14 |
| An Online Tailored Cognitive Therapy-Based Intervention for Depression in Multiple Sclerosis: ACTION-MS Online ACTION-MS website - an 8-week cognitive behavioural therapy intervention for depression., The 'Health and Wellbeing in MS' website - Depression and Anxiety Symptoms, Multiple Sclerosis | Not applicable | Not yet recruiting | University of Melbourne | 240 | 2026-11-01 | 2026-10-15 |
| Stopping Strep Throat With Antibodies in Healthy Adults. Streptococcus pyogenes M1 challenge strain, Intravenous immunoglobulin (IVIG), Saline (NaCl 0,9 %) (placebo) - Streptococcal Pharyngitis | Phase 1 | Not yet recruiting | Murdoch Childrens Research Institute | 60 | 2026-10-01 | 2026-10-07 |
| Remote Monitoring for Patients With Aortic Stenosis Aortic Stenosis | Not yet recruiting | Baker Heart and Diabetes Institute | 160 | 2026-09-01 | 2026-07-08 | |
| Mechanisms of Change in Behavioral Cough Suppression Therapy for Refractory Chronic Cough BCS+inactive, BCS+active - Chronic Cough (CC), Refractory Chronic Cough | Phase 2 | Recruiting | University of Montana | 135 | 2026-08-13 | 2026-08-18 |
| Adjuvant Clopidogrel in Staphylococcus Aureus Bacteremia Clopidogrel, No antiplatelet treatment - Bacteremia Due to Staphylococcus Aureus | Phase 2 | Not yet recruiting | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 230 | 2026-06-01 | 2026-02-05 |
| An Ultra-short Course of Primaquine for the Radical Cure of Vivax Malaria High dose ultra short Primaquine, Placebo - Malaria | Phase 3 | Not yet recruiting | Menzies School of Health Research | 1019 | 2026-06-01 | 2026-03-12 |
| Phase II Trial of Lu-177 FAP-2286 in Patients With Carcinoma of Unknown Primary 177Lu-FAP-2286 - Cancer of Unknown Primary | Phase 2 | Not yet recruiting | Peter MacCallum Cancer Centre, Australia | 20 | 2026-06-01 | 2026-02-25 |
| Evaluation and Demonstration of New Tuberculosis Diagnostics for Indonesia nPOC Testing Intervention Package - Tuberculosis | Not applicable | Recruiting | Universitas Padjadjaran | 40000 | 2026-04-01 | 2026-09-25 |
| ListenFuture-Listening for Their Future: Deaf and Hard-of-Hearing Adolescents Hearing Disorders and Deafness | Recruiting | Heikki Löppönen | 256 | 2026-03-01 | 2026-02-25 | |
| Evaluating Safe Ketone Thresholds To Minimise Ketosis in People With Type 1 Diabetes Using Dapagliflozin FORXIGA - Type 1 Diabetes Mellitus | Phase 2 | Not yet recruiting | St Vincent's Hospital Melbourne | 115 | 2026-02-01 | 2025-11-06 |
| Dabigatran vs. Oral Anti-Xa Inhibitors in S. Aureus Bacteremia Dabigatran, Apixaban, edoxaban - Staphylococcus Aureus Endocarditis, Staphylococcus Aureus Septicemia | Phase 4 | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 300 | 2026-01-15 | 2026-09-24 |
| Investigating the Efficacy of a Paediatric Fertility Preservation Decision Aid in Parents and Adolescents and Young Adults (CAYA) Cancer Survivors Decision-aid - Unmet Fertility Information Needs | Not applicable | Recruiting | Murdoch Childrens Research Institute | 358 | 2025-12-08 | 2026-10-16 |
| Pasteurised Donor Human Milk Supplementation for Term Babies Standard care Cow's milk based formula, Dietary Supplement: PDHM Pasteurised Donor Human Milk - Neonatal Hypoglycemia, Metabolic Complication | Phase 4 | Recruiting | The University of Queensland | 1444 | 2025-12-04 | 2026-09-02 |
| Adjunctive Rifampin for the Treatment of Prosthetic Valve Endocarditis Due to S. Aureus Rifampin, No rifampin - Staphylococcus Aureus Endocarditis, Prosthetic Valve Endocarditis | Phase 3 | Terminated | Todd C. Lee MD MPH FIDSA | 1 | 2025-11-10 | 2026-09-21 |
| PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol] Erythromycin, Amoxicillin and Erythromycin, Azithromycin - Preterm Birth | Not applicable | Not yet recruiting | University of Melbourne | 100000 | 2025-11-01 | 2025-06-13 |
| SOS for Caregiver Wellbeing Screening, Outcomes and Referral Pathways - Mental Health, Depression and Burden in Caregivers | Not applicable | Active not recruiting | Murdoch Childrens Research Institute | 123 | 2025-10-22 | 2026-10-09 |
| Closed Loop and Education for Hypoglycemia Awareness Restoration Omnipod 5 or Medtronic 780G, My HypoCOMPaSS Education, HARPdoc Education - Diabetes Mellitus, Type 1 | Not applicable | Recruiting | Milton S. Hershey Medical Center | 324 | 2025-10-03 | 2026-03-03 |
| Caffeine Citrate to Improve Neonatal Outcomes. Caffeine citrate - Apnea of Prematurity | Not applicable | Not yet recruiting | University of Melbourne | 3900 | 2025-10-01 | 2025-05-15 |
| Preterm Rupture of Membranes Optimising Antibiotics Trial Erythromycin 250mg + placebo, Azithromycin 500mg + placebo, Erythromycin 250mg and Amoxicillin 500mg - PPROM, Preterm | Not applicable | Not yet recruiting | University of Melbourne | 3900 | 2025-09-01 | 2025-04-02 |
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Depression (14) · Motor Activity (12) · Osteoarthritis, Knee (10) · Obesity (8) · Psychological Well-Being (8) · Stroke (8) · COVID-19 (7) · Ischemic Stroke (7) · Osteoarthritis (7) · Malaria, Vivax (6) · Myopia (6) · Dementia (5) · Malaria (5) · Premature Birth (5) · Anxiety Disorders (4)
Exercise (8) · Standard of Care (7) · Azithromycin (6) · Educational Status (5) · fanasil, pyrimethamine drug combination (5) · Sodium Chloride (4) · Cognitive Behavioral Therapy (3) · Primaquine (3) · Saline Solution (3) · 23-valent pneumococcal capsular polysaccharide vaccine (2) · Amoxicillin (2) · Daptomycin (2) · Erythromycin (2) · Self-Help Groups (2) · Tenecteplase (2)
Australia (144) · United States (14) · United Kingdom (11) · Canada (9) · Norway (8) · Papua New Guinea (8) · New Zealand (7) · Indonesia (6) · Singapore (6) · Finland (5) · Germany (5) · Israel (5) · Netherlands (5) · Sweden (5) · Brazil (4)
Kim Bennell, PhD (5) · Mary P Galea, PhD (5) · Kim L Bennell, PhD (4) · Jeannette Milgrom, PhD (3) · Sharon Lewin (3) · Bruce Campbell (2) · Carol Lakkis, BScOptom, PhD, PGCertOcTher (2) · Clare Whitehead, MBChB, PhD (2) · John W Wilson, MBBS, PhD (2) · Peter De Cruz, MBBS PhD FRACP (2) · Ross M Andrews, PhD (2) · Sharon R Lewin, FRACP, PhD (2) · Abbey Sawyer, PhD (1) · Adam Kucharski, MMath, PhD (1) · Adrian J Lowe, Doctorate (1)
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2025 (4), 2023 (1), U01AI060579 (1), U01DK135126 (1), U01DK143330 (1)