41 completed, 8 recruiting, 7 not yet recruiting, 2 terminated. 34 Not applicable, 8 Phase 4, 3 Phase 2, 2 Phase 3.
Follow Chlamydia: new trials by email Literature Review of Chlamydia trials Research Report on Chlamydia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| Improving Clinic Delivery of HIV-related Anal Health Services PEACHES 2.0 Implementation Strategies - HIV, Gonorrhea | Not applicable | Not yet recruiting | Albert Einstein College of Medicine | 8 | 2028-02-01 | 2026-10-13 |
| A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African Women Doxycycline hyclate, Standard of Care for STI prevention - Sexually Transmitted Infection (STI), Gonorrhea | Phase 3 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 580 | 2026-11-30 | 2026-10-20 |
| Pilot HIV Self-Testing And Self-collected STI Testing Strategy for Sex Worker Empowerment Study Venue-based, peer-enhanced strategy for integrated HIV self-testing (and self-collected STI testing - HIV, Syphilis | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 232 | 2026-11-01 | 2026-10-29 |
| Daily, Weekly, or Event-driven Doxycycline for STI Prevention Among Men Who Have Sex With Men (MSM) Engaging in Chemsex: The DOSE Non-inferiority Trial On demand doxycycline hyclate 200mg, Daily doxycycline hyclate 100mg, Weekly doxycycline hyclate 100mg - Gonorrhea, Chlamydia | Phase 4 | Not yet recruiting | University of California, Los Angeles | 300 | 2026-11-01 | 2026-11-09 |
| National Rapid TLC: Testing and Linkage to Care Xpert® HIV-1 Qual XC - HIV, Chlamydia | Not applicable | Not yet recruiting | Unity Health Toronto | 2500 | 2026-08-01 | 2026-07-28 |
| Healthy Expectancy Through Routine Antenatal STI Screening Chlamydia trachomatis and Neisseria gonorrhoeae screening - Antenatal Health, Antenatal Care | Not applicable | Recruiting | Adriane Wynn | 2000 | 2026-05-25 | 2026-07-02 |
| Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, Switzerland HIV (Human Immunodeficiency Virus), Chlamydia | Not yet recruiting | University of Zurich | 1800 | 2026-04-07 | 2026-04-08 | |
| Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections Doxycycline hyclate delayed released 200 mg, Doxycycline hyclate delayed released 200 mg weekly, Per standard of care with quarterly STI testing/treatment and sexual health counseling - Gonorrhea, Chlamydia | Phase 4 | Recruiting | Westat | 760 | 2026-02-27 | 2026-10-16 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand. Doxycycline (200mg/day) - Syphilis Infection, Gonorrhea | Phase 4 | Recruiting | Bangrak STIs Center | 400 | 2025-10-06 | 2026-02-09 |
| A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities Chlamydia, gonorrhea, syphilis, and HIV screening - Chlamydia, Gonorrhea | Not applicable | Recruiting | Tulane University | 2322 | 2025-08-14 | 2026-09-21 |
| Assessing Acceptability and Feasibiity of STI Self-swab Testing, to be Offered at the Time of Telemed Medication Abortion Provision Self-swab collection PCR test for chlamydia, gonorrhea, trichomonas - Sexually Transmitted Disease (STD), Gonorrhea | Not applicable | Recruiting | Queen's Medical Center | 75 | 2025-05-22 | 2025-06-26 |
| Superiority of On-demand PrEP Versus PEP on Using Doxycycline for Preventing STI in MSM DoxyODPrEP, DoxyPEP - Sexually Transmitted Diseases, Bacterial, Syphilis | Phase 4 | Active not recruiting | Chinese University of Hong Kong | 300 | 2025-03-29 | 2026-06-05 |
| Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening Motivational interviewing and specimen self-collection - Sexually Transmitted Diseases, Gonorrhea | Not applicable | Completed | University of Michigan | 75 | 2024-04-19 | 2025-07-01 |
| Combination Primary Care and Prevention Services for Women Who Inject Drugs and Exchange Sex in Seattle, Washington Mobile Van Clinic - Opioid Use Disorder, HIV Infections | Not applicable | Completed | University of Washington | 50 | 2024-03-18 | 2026-02-20 |
| Screening With Tampons: Evaluating Diagnostic Accuracy and HPV and Assessing Participant Views DAYE Diagnostic Tampon, Vaginal self-swab, Clinician vaginal swab - Chlamydia, Gonorrhea | Not applicable | Completed | Anne's Day Ltd | 617 | 2024-01-15 | 2025-07-31 |
| Meatal Swab Yourself With Testing for Infections Collectively All participants - Chlamydia, Gonorrhea | Not applicable | Unknown | The Leeds Teaching Hospitals NHS Trust | 1250 | 2023-07-18 | 2023-12-22 |
| A Study to Learn About How Trumenba Vaccine Shots Work Against Gonorrhea Infection in Teenagers and Young Adults in the United States. Trumenba Vaccine, MenACWY Vaccine - Gonorrhea, Chlamydia | Completed | Pfizer | 1307378 | 2023-04-24 | 2025-04-17 | |
| Pay-it-forward Gonorrhea and Chlamydia Testing Among Men in China Standard Pay-it-forward, Community Engaged Pay-it-forward, Control arm - Gonorrhea, Chlamydia | Not applicable | Completed | University of North Carolina, Chapel Hill | 1200 | 2023-04-01 | 2025-12-03 |
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Chlamydia Infections (61) · Gonorrhea (48) · Sexually Transmitted Diseases (21) · Syphilis (19) · Acquired Immunodeficiency Syndrome (7) · Trichomonas Infections (7) · HIV Infections (6) · Emergencies (3) · Homosexuality (3) · Sexual Behavior (3) · Trachoma (3) · Bacterial Infections (2) · Coitus (2) · Eye Diseases (2) · Hepatitis C (2)
Bacterial Infections and Mycoses (61) · Chlamydiaceae Infections (61) · Genital Diseases (61) · Gram-Negative Bacterial Infections (61) · Infections (61) · Urogenital Diseases (61) · Communicable Diseases (60) · Sexually Transmitted Diseases, Bacterial (60) · Bacterial Infections (59) · Neisseriaceae Infections (48) · Sexually Transmitted Diseases (40) · Disease Attributes (24) · Pathologic Processes (24) · Pathological Conditions, Signs and Symptoms (24) · Spirochaetales Infections (20)
Azithromycin (2) · Doxycycline (2) · HIV Testing (2) · Standard of Care (2) · Ceftriaxone (1) · Delivery of Health Care, Integrated (1) · MenB-FHbp vaccine (1) · Methods (1) · Motivational Interviewing (1) · Sex (1) · Therapeutics (1)
University of California, San Francisco (6) · Northwestern University (5) · University of California, Los Angeles (4) · University of Pittsburgh (3) · Centers for Disease Control and Prevention (2) · Johns Hopkins Bloomberg School of Public Health (2) · University of California, San Diego (2) · University of North Carolina, Chapel Hill (2) · Washington University School of Medicine (2) · Adriane Wynn (1) · Albert Einstein College of Medicine (1) · Anne's Day Ltd (1) · Bangrak STIs Center (1) · Children's Hospital Medical Center, Cincinnati (1) · Chinese University of Hong Kong (1)
United States (36) · Ethiopia (3) · Botswana (2) · China (2) · Mexico (2) · Peru (2) · United Kingdom (2) · Austria (1) · Cambodia (1) · Canada (1) · Eswatini (1) · Hong Kong (1) · Malawi (1) · South Africa (1) · Sweden (1)
Jim Carey, MPH (3) · Brian Mustanski, PhD (2) · Jesse L Clark, MD, MSc (2) · Kieran S O'Brien, MPH (2) · Michael E Newcomb, Ph.D. (2) · Paul Emerson, PhD (2) · Ricky Hill, Ph.D. (2) · Tom Lietman, MD (2) · Akshay Sharma, PhD (1) · Allison K Groves, PhD, MHS (1) · Anne Luetkemeyer, MD (1) · Audun J Lier, MD (1) · Brian Mustanski, Ph.D (1) · Bryan Kutner, PhD, MPH (1) · Catherine Maher, PhD (1)
PMID 21099596, PMID 37018493, PMID 37351709, PMID 15937765, PMID 17051493, PMID 19329003, PMID 19591608, PMID 20308834, PMID 20335410, PMID 20585275, PMID 21124216, PMID 21685340, PMID 22095569, PMID 22192488, PMID 22736616, PMID 23107285, PMID 24621121, PMID 26718807, PMID 27129956, PMID 28062389, PMID 28468648, PMID 29191814, PMID 29229440, PMID 29937115, PMID 30106956, PMID 30107833, PMID 30204761, PMID 31166952, PMID 31791323, PMID 32012111, PMID 32444901, PMID 33835852, PMID 34143341, PMID 34392717, PMID 34852691, PMID 35418329, PMID 35725624, PMID 37021692, PMID 37080628, PMID 37141032, PMID 37337181, PMID 38118022, PMID 38656217, PMID 38797183, PMID 39192345, PMID 39208425, PMID 39363100, PMID 39387999, PMID 39992776, PMID 40147465
U19AI084024 (2), 1IK2CX002822-01A1 (1), 5UM1AI106707 (1), D43TW009340 (1), R01AI143439 (1), R01AI158826 (1), R01CA321103 (1), R01DA035145 (1), R01DA066392 (1), R01HD094213 (1), R01HD116989 (1), R01MH075639 (1), R01MH087054 (1), R01MH092226 (1), R01NR014632 (1)