13 completed, 12 recruiting, 10 not yet recruiting, 8 active not recruiting. 8 Not applicable, 7 Phase 2, 3 Phase 3, 2 Phase 1, 1 Phase 4.
Follow Charcot-Marie-Tooth disease, Type 1F: new trials by email Literature Review of Charcot-Marie-Tooth disease, Type 1F trials Research Report on Charcot-Marie-Tooth disease, Type 1F
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Blood NfL and Functional Outcomes After Moderate-to-Severe TBI neurofilament light chain ECLIA - Traumatic Brain Injury | Not yet recruiting | Rutgers, The State University of New Jersey | 175 | 2027-05-01 | 2026-10-28 | |
| Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage Intracerebral Hemorrhage, Hemorrhagic Stroke | Not yet recruiting | University Medical Centre Maribor | 300 | 2026-11-01 | 2026-10-20 | |
| Neurostructural and Biochemical Signatures of Tobacco Smoking in Mood Disorders Major Depressive Disorder, Bipolar Disorder | Not yet recruiting | Assiut University | 240 | 2026-11-01 | 2026-11-02 | |
| Study on Thiamine Supplementation to REduce braiN Injury Associated With Chronic Alcohol Use in Outpatients With Alcohol Use Disorder Thiamine - Alcohol Use Disorder | Phase 2 | Not yet recruiting | Institut National de la Santé Et de la Recherche Médicale, France | 60 | 2026-10-23 | 2026-09-28 |
| Register for Medical Data, Functional Scales, and Care Outcomes in ALS, SMA, and Other Motor System Disorders Standard of Care (Investigator Choice) - ALS (Amyotrophic Lateral Sclerosis), SMA - Spinal Muscular Atrophy | Recruiting | Ambulanzpartner Soziotechnologie APST GmbH | 2000 | 2026-10-01 | 2026-10-28 | |
| Early Versus Delayed Start of Ocrevus Zunovo for Relapsing Multiple Sclerosis Relapse Remitting Multiple Sclerosis | Recruiting | Oklahoma Medical Research Foundation | 45 | 2026-09-30 | 2026-10-16 | |
| Kinetics and Prognostic Value of NeuroFilament Light in Post-cardiac Arrest: A Prospective Multicenter Study Value of neurofilament light chain (NFL) at different time points - Cardiac Arrest (CA), Intensive Care Unit (ICU) Admission | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 270 | 2026-09-01 | 2026-08-12 | |
| Developing New Ways to Detect Respiratory Impairment Early in ALS Amyotrophic Lateral Sclerosis (ALS) | Recruiting | Thomas Jefferson University | 70 | 2026-09-01 | 2026-09-28 | |
| DIV-AD BARCELONA: Alzheimer's Blood-Based Biomakers for a Diverse Community Alzheimer Disease, Cognitive Dysfunction, Cognitive Disorder | Not yet recruiting | Barcelonabeta Brain Research Center, Pasqual Maragall Foundation | 250 | 2026-04-27 | 2026-04-13 | |
| Impact of Exercise Training on Serum Neurofilament Light Chain (NfL), Brain Volumetry, and Functional Outcomes in Multiple Sclerosis Exercise - Multiple Sclerosis, Exercise | Not applicable | Not yet recruiting | Firat University | 26 | 2026-04-15 | 2026-04-09 |
| Analysis of NfL and GFAP in Different Dietary Patterns Neurofilament Light Chain, Glial Fibrillary Acidic Protein | Recruiting | Salzburger Landeskliniken | 300 | 2025-12-18 | 2025-12-31 | |
| A Study of a Blood Marker in Newborns With Brain Injury Caused by Lack of Oxygen at Birth Hypoxic-Ischemic Encephalopathy | Not yet recruiting | Mustafa Gürkan | 20 | 2025-12-15 | 2025-12-18 | |
| Evaluation of Functional and Biochemical Effectiveness of a Strength Training Protocol in Parkinson's Disease strength training - Parkinson Disease | Not applicable | Not yet recruiting | Universidad Villanueva | 22 | 2025-09-07 | 2025-07-31 |
| Neurofilament Light Chain Correlation With Severity of Symptoms and Cognitive Decline in Mood Disorders serum level of neurofilament light chain - Mood Disorders | Not yet recruiting | Assiut University | 90 | 2025-05-01 | 2025-03-14 | |
| Non-Invasive Brain Stimulation to Improve Language in Down Syndrome. Active Group (Active Anodal tDCS to the left IFG or Cathodal tDCS to the left IFG), Sham Group - Down Syndrome | Not applicable | Recruiting | Floriana Costanzo | 36 | 2025-01-27 | 2026-07-24 |
| Comparison of Efficacy and Safety in Patients Switching From MabThera® to Rixathon® in Relapsing-Remitting Multiple Sclerosis MS (Multiple Sclerosis), Multiple Sclerosis (MS) - Relapsing-remitting | Active not recruiting | Uppsala University | 184 | 2025-01-01 | 2025-11-19 | |
| Predict to Prevent PGRN Disease Clinical, behavioral and cognitive evaluation, blood sampling, brain MRI - Frontotemporal Dementia (FTD), GRN Related Frontotemporal Dementia | Not applicable | Withdrawn | Assistance Publique - Hôpitaux de Paris | 2025-01-01 | 2025-03-21 | |
| ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS ETNATM-ProgMS - Relapsing Remitting Multiple Sclerosis (RRMS) | Phase 4 | Recruiting | Novartis Pharmaceuticals | 224 | 2024-11-27 | 2026-05-15 |
| Lithium for Parkinson's: an Extension Trial Lithium aspartate - Parkinson Disease | Phase 1 / Phase 2 | Enrolling by invitation | State University of New York at Buffalo | 35 | 2024-08-09 | 2026-10-26 |
| Early Detection of Brain Injury After Congenital Heart Surgery in Infants Observational study: blood analisys, EEG, MRI - Congenital Heart Disease (CHD), Hypoxic Encephalopathy | Enrolling by invitation | University Medical Centre Ljubljana | 30 | 2024-05-03 | 2026-03-10 |
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Multiple Sclerosis (8) · Amyotrophic Lateral Sclerosis (5) · Brain Injuries, Traumatic (4) · Cognitive Dysfunction (4) · Alzheimer Disease (3) · Dementia (3) · Disease Progression (3) · Frontotemporal Dementia (3) · Motor Neuron Disease (3) · Multiple Sclerosis, Chronic Progressive (3) · Multiple Sclerosis, Relapsing-Remitting (3) · Nerve Degeneration (3) · Neurodegenerative Diseases (3) · Brain Injuries (2)
Nervous System Diseases (41) · Central Nervous System Diseases (24) · Pathological Conditions, Signs and Symptoms (24) · Brain Diseases (20) · Pathologic Processes (16) · Mental Disorders (12) · Neurodegenerative Diseases (12) · Cardiovascular Diseases (9) · Demyelinating Autoimmune Diseases, CNS (9) · Immune System Diseases (9) · Signs and Symptoms (9) · Autoimmune Diseases (8) · Autoimmune Diseases of the Nervous System (8) · Demyelinating Diseases (8) · Disease Attributes (8)
Blood Specimen Collection (3) · Spinal Puncture (3) · remibrutinib (2) · teriflunomide (2) · Anesthesia, General (1) · Anesthetics, General (1) · Capsules (1) · Cladribine (1) · Exercise (1) · Fish Oils (1) · Hematologic Tests (1) · Magnetic Resonance Spectroscopy (1) · Mental Status and Dementia Tests (1) · Natalizumab (1) · Prolactin-Releasing Hormone (1)
Novartis Pharmaceuticals (4) · Ambulanzpartner Soziotechnologie APST GmbH (2) · Assistance Publique - Hôpitaux de Paris (2) · Assiut University (2) · Queen Mary University of London (2) · University Hospital Hradec Kralove (2) · University Hospital, Basel, Switzerland (2) · Affiliated Hospital of Jiaxing University (1) · Amsterdam UMC, location VUmc (1) · Barcelonabeta Brain Research Center, Pasqual Maragall Foundation (1) · Baskent University (1) · Cardiocentro Ticino (1) · Centre Hospitalier Universitaire de Nīmes (1) · Chang Gung Memorial Hospital (1) · Charite University, Berlin, Germany (1)
United States (11) · Germany (6) · United Kingdom (6) · Austria (5) · Spain (5) · Turkey (Türkiye) (5) · China (4) · Czechia (4) · France (4) · Italy (4) · Switzerland (4) · Bulgaria (3) · Canada (3) · Slovakia (3) · Slovenia (3)
Miroslav Cihlo, M.D. (2) · Aaron F Carbuhn, PhD (1) · Allison Moore (1) · Byron Gajewski, PhD (1) · Eric Thouvenot (1) · Florence Vorspan, MD PhD (1) · Floyd Chilton, Ph.D. (1) · Frederick Korley, MD, PhD (1) · Gaylan Rockswold, MD, PhD (1) · Hossam E Khalifa (1) · Joachim Burman, MD, PhD (1) · Joep Killestein, MD, PhD. (1) · Katharina Timper, Prof. (1) · Klaus Schmierer (1)
PMID 29734566, PMID 34605319, PMID 35604539, PMID 36188406, PMID 36534274, PMID 38000822, PMID 38702240, PMID 41409494, PMID 41684415
2023 (2), 2018 (1), 2019 (1), 2025 (1), R21NS145175 (1)