9 completed, 5 unknown, 1 active not recruiting, 1 terminated. 16 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Completed 9, Unknown 5, Active not recruiting 1, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
Follow Caries: new trials by email Literature Review of Caries trials Research Report on Caries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| New In Situ Model Design for Caries and Erosion 0 ppm fluoride toothpaste, 250 ppm fluoride toothpaste (dose-response control), 1150 ppm fluoride toothpaste - Caries, Erosive Tooth Wear | Phase 3 | Active not recruiting | Indiana University | 12 | 2026-08-03 | 2026-09-30 |
| In Situ Comparison of the Remineralization Potential of Optimized Fluoride Dentifrice With Control Fluoride Dentifrice 0 ppm F (placebo, negative control), 1100 ppm F as sodium fluoride (positive control), 1100 ppm F as sodium fluoride Test Product - Caries | Phase 3 | Completed | Indiana University | 52 | 2023-10-02 | 2025-06-15 |
| Randomized Clinical Trial: Oral Health Package Law and Fluor Varnish Impact on Schoolchildren in Merida, Mexico Fluoride varnish, Fluoride toothpaste - Caries, Gum Disease | Phase 3 | Unknown | Anahuac Mayab University | 900 | 2023-06-22 | 2023-07-25 |
| Pulpotomy in Primary Molars Treated With Premixed Bio-ceramic MTA Versus Formocresol Formocresol, Premixed bioceramic MTA - Caries | Phase 3 | Unknown | Sarah Abdelbar Mahmoud | 40 | 2022-04-01 | 2022-04-06 |
| The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth Nanosilver Fluoride (NSF), Silver diamine fluoride - Primary Teeth, Microbial Colonization | Phase 3 | Terminated | Nour Ammar, BDS | 50 | 2022-03-15 | 2023-08-18 |
| The Efficiency and Gingival Health Status of Hall Versus SDF Techniques in the Management of Carious Primary Molars Silver diamine fluoride, hall technique - Caries | Phase 3 | Unknown | Sarah Abdalla Ibrahim Abdalla | 40 | 2021-09-01 | 2021-05-17 |
| Post-operative Pain and Child Behavior of Hall Technique Versus SDF in the Management of Carious Primary Molars: RCT Silver diamine fluoride, Hall Technique - Caries | Phase 3 | Unknown | Noura Mohamed Alhosaini | 40 | 2021-06-01 | 2021-05-12 |
| Caries Prevention and Side Effects of Gum Arabic and Licorice Extracts Versus Chlorhexidine in High Caries Risk Patients Arabic, Gum, Licorice Root, Chlorhexidine - High Caries Risk Patients, Caries | Phase 2 / Phase 3 | Completed | Cairo University | 63 | 2019-12-10 | 2020-02-28 |
| Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer Glass Ionomer, Chitosan Low Molecular Weight (20-200 Mpa.S), Chlorhexidine Diacetate - Reversible Pulpitis, Pulpitis | Phase 3 | Completed | Ain Shams University | 65 | 2019-01-15 | 2021-01-12 |
| Effect of CPP-ACP With/Without Fl on White Spot Lesion,Salivary pH and fl Release in High Caries Risk Patients CPP-ACP paste - Caries | Phase 3 | Unknown | Cairo University | 42 | 2018-10-01 | 2018-09-06 |
| Evaluation of the Fluoride Dose Response of a Modified In Situ Caries Model 0 ppm F (placebo, negative control), 250 ppm F as NaF (dose-response control), 500 ppm F as NaF (dose-response control) - Caries | Phase 3 | Completed | Domenick Zero | 28 | 2017-12-19 | 2019-05-20 |
| Effectiveness of Silver Diamine Fluoride as a Treatment for Caries in Comparison to Traditional Restorative Techniques Silver Diamine Fluoride, Conventional Caries Management - Caries | Phase 3 | Completed | University of Michigan | 98 | 2016-01-01 | 2021-11-22 |
| Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth Mineral trioxide aggregate, Calcium hydroxide, Biodentine - Caries, Dental Pulp Exposure | Phase 2 / Phase 3 | Completed | Universidad de los Andes, Chile | 169 | 2014-04-01 | 2024-05-30 |
| In Situ Caries Model of Fluoride Toothpastes Sodium Fluoride Toothpaste, Amine Fluoride Toothpaste, Sodium monofluorophosphate/Sodium Fluoride Toothpaste - Caries | Phase 3 | Completed | GlaxoSmithKline | 65 | 2008-11-01 | 2013-07-29 |
| In Situ Caries Efficacy of Fluoride Toothpastes NaF, Placebo, NaMFP - Caries | Phase 3 | Completed | GlaxoSmithKline | 57 | 2008-04-01 | 2015-01-01 |
| In Situ Caries of Fluoride Toothpastes Sodium fluoride toothpaste, Placebo toothpaste - Healthy Subjects, Partial Denture Wearers | Phase 3 | Completed | GlaxoSmithKline | 60 | 2007-11-01 | 2013-04-22 |
Dental Caries (2) · Communicable Diseases (1) · Dental Pulp Exposure (1) · Gingival Diseases (1) · Gingival Recession (1) · Pulpitis (1)
Stomatognathic Diseases (5) · Tooth Diseases (3) · Dental Pulp Diseases (2) · Mouth Diseases (2) · Periodontal Diseases (2) · Tooth Demineralization (2) · Disease Attributes (1) · Gingival Diseases (1) · Infections (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Periodontal Atrophy (1)
silver diamine fluoride (3) · Chlorhexidine (2) · Fluorides (2) · Calcium Hydroxide (1) · Glycyrrhiza glabra extract (1) · Gum Arabic (1) · Sodium Fluoride (1) · chlorhexidine gluconate (1) · fluorophosphate (1) · formocresol (1) · fuji IX (1) · glass ionomer (1) · hydrated silica gel-based toothpaste (1) · mineral trioxide aggregate (1) · titanium dioxide (1)
GlaxoSmithKline (3) · Cairo University (2) · Indiana University (2) · Ain Shams University (1) · Anahuac Mayab University (1) · Domenick Zero (1) · Nour Ammar, BDS (1) · Noura Mohamed Alhosaini (1) · Sarah Abdalla Ibrahim Abdalla (1) · Sarah Abdelbar Mahmoud (1) · Universidad de los Andes, Chile (1) · University of Michigan (1)
United States (5) · Egypt (3) · Chile (1) · Mexico (1)
Anderson Hara, DDS, PhD (3) · Frank Lippert, PhD (2) · Claudia Brizuela (1) · Domenick T Zero, DDS, MS (1) · Domenick Zero, DDS, MS (1) · Margherita R Fontana, DDS, PhD (1) · Mariem Wassel, Assistant professor (1) · Mohamed R Farid, PhD (1) · Noha Kabil, Professor (1) · Nour Ammar, BDS (1) · Sherif B Eltaweil, Prof (1)
PMID 26079388, PMID 27766712, PMID 28190299, PMID 31158253, PMID 32522320, PMID 35120408, PMID 35804457, PMID 36585664, PMID 40490725