12 completed, 7 unknown, 3 recruiting. 12 Not applicable, 9 Phase 2, 5 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 8, Unknown 3, Recruiting 1 |
| Phase 2 | 9 | Completed 4, Unknown 4, Recruiting 1 |
| Phase 3 | 5 | Unknown 3, Completed 1, Recruiting 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow Gum Arabic: new trials by email Literature Review of Gum Arabic trials Research Report on Gum Arabic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized Anti-Inflammatory Fibres in Ulcerative Colitis Acacia Gum, Microcrystalline Cellulose, Placebo - Ulcerative Colitis | Not applicable | Recruiting | University of Alberta | 69 | 2025-06-03 | 2026-06-05 |
| The Effect of Gum Arabic (GA) on Residual Renal Function in Adult Dialysis Patients in Abu Dhabi Gum Arabic, Water - End Stage Renal Disease (ESRD) | Phase 1 / Phase 2 | Recruiting | Abu Dhabi Health Services Company | 40 | 2025-02-03 | 2025-02-20 |
| Impact of Gum Acacia on Chronic Kidney Disease Patients Gum acacia - Chronic Kidney Diseases | Not applicable | Completed | Alexandria University | 80 | 2022-07-18 | 2023-06-22 |
| Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance Metformin 850 mg oral tablet bid, Supplemental fiber mixture (35 g total) composed of 6g of Oligofructose + 12g of resistant maltodextrin + 12g of acacia gum + 5g of PGX. - Obesity, Childhood, Insulin Resistance | Phase 3 | Recruiting | University of Alberta | 90 | 2021-10-22 | 2026-10-23 |
| Interaction Between Cannabidiol, Meal Ingestion, and Liver Function Cannabidiol (CBD) powder formulation, Cannabidiol (CBD) Oil based tincture formulation, Cannabidiol (CBD) Gum Arabic, maltodextrin base formulation - Metabolism, Liver Function | Not applicable | Completed | Colorado State University | 26 | 2021-05-20 | 2024-11-15 |
| Remineralization Efficacy of Gum Arabic Varnish. Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc. - Caries,Dental, Remineralization | Phase 2 / Phase 3 | Unknown | Cairo University | 90 | 2020-10-01 | 2020-07-13 |
| The Effect of Different Prebiotics on Iron Absorption From High Dose Iron Supplements ferrous fumarate, ferrous fumarate + 15 g GOS, ferrous fumarate + 15 g FOS - Iron-deficiency | Not applicable | Completed | Swiss Federal Institute of Technology | 30 | 2020-07-20 | 2021-01-22 |
| Evaluation of Acacia Gum on Microbiome and Bowel Function in Participants With Chronic Constipation acacia gum - Constipation | Not applicable | Completed | Alpinia Laudanum GmbH | 12 | 2020-06-01 | 2021-01-12 |
| Potential Role of Gum Arabic as Immunomodulatory Agent Among COVID 19 Patients Acacia Senegal, Pectin - COVID 19 | Phase 2 / Phase 3 | Unknown | Al-Neelain University | 110 | 2020-06-01 | 2020-05-12 |
| Gum Arabic as Anti-oxidant, Anti-inflammatory and Fetal Hemoglobin Inducing Agent in Sickle Cell Anemia Patients Acacia Senegal extract, Pectin - Sickle Cell Anemia in Children | Phase 2 / Phase 3 | Unknown | Al-Neelain University | 100 | 2020-02-15 | 2020-01-28 |
| Effects of Gum Arabic Ingestion on Hormonal and Metabolic Changes in Patients With Polycystic Ovary Syndrome Acacia Senegal extract, Pectin - Polycystic Ovary Syndrome | Not applicable | Unknown | Lamis Kaddam | 60 | 2020-01-25 | 2020-01-23 |
| Caries Prevention and Side Effects of Gum Arabic and Licorice Extracts Versus Chlorhexidine in High Caries Risk Patients Arabic, Gum, Licorice Root, Chlorhexidine - High Caries Risk Patients, Caries | Phase 2 / Phase 3 | Completed | Cairo University | 63 | 2019-12-10 | 2020-02-28 |
| Effects of Gum Arabic on Metabolic Syndrome Parameters in Postmenopausal Women Gum Arabic - Metabolic Syndrome in Postmenopausal Females | Phase 2 | Completed | University of Khartoum | 100 | 2019-12-04 | 2026-02-18 |
| Study to Evaluate the Effect of Gum Acacia (FibregumTM) on Post-prandial Glucose, Insulin Levels and Food Intake 40 g Gum acacia (FibregumTM), 20 g Gum acacia (FibregumTM), 0 g Gum acacia (FibregumTM) - Healthy, Overweight | Not applicable | Completed | Nexira | 36 | 2019-06-28 | 2020-08-19 |
| Effect of Gum Arabic on Gastrointestinal Transit and Permeability High-dose prebiotic, Low-dose prebiotic, Placebo - Diverticulitis | Not applicable | Completed | Mayo Clinic | 27 | 2018-12-18 | 2023-07-10 |
| Effects of Gum Arabic Supplementation in Hemodialysis Patients Gum Arabic, Placebo - Kidney Failure, Chronic | Not applicable | Unknown | University of Khartoum | 80 | 2018-11-01 | 2019-01-03 |
| The Need for FibEr Addition in SympTomatic Heart Failure Acacia Gum - Heart Failure | Not applicable | Completed | University of Alberta | 51 | 2018-09-13 | 2022-08-18 |
| Gum Arabic as Antioxidant and Anti-inflammatory in Hemodialysis Patients Gum Arabic - End-Stage Renal Disease | Not applicable | Unknown | Lamis Kaddam | 50 | 2017-07-01 | 2017-07-11 |
| Gum Arabic as Immunomodulator In Rheumatoid Arthritis Patients Gum Arabic - Rheumatoid Arthritis | Phase 2 | Unknown | Lamis Kaddam | 45 | 2016-06-01 | 2016-06-21 |
| Using Gum Arabic for Cancer Patients to Protect From Oral Mucositis Caused by Chemotherapy: ِِِAn Experimental Study Gum Arabic, Chemotherapy, Lifestyle counseling - Chemotherapy-induced Oral Mucositis | Phase 2 | Completed | University of Science and Technology, Yemen | 386 | 2015-10-26 | 2017-11-20 |
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Kidney Failure, Chronic (3) · Anemia, Sickle Cell (2) · Anemia, Iron-Deficiency (1) · Arthritis, Rheumatoid (1) · COVID-19 (1) · Cardiovascular Diseases (1) · Colitis, Ulcerative (1) · Constipation (1) · Dental Caries (1) · Diverticulitis (1) · Fecal Incontinence (1) · Heart Diseases (1) · Heart Failure (1) · Inflammatory Bowel Diseases (1) · Insulin Resistance (1)
Al-Neelain University (3) · Lamis Kaddam (3) · University of Alberta (3) · Cairo University (2) · University of Khartoum (2) · Abu Dhabi Health Services Company (1) · Alexandria University (1) · Alpinia Laudanum GmbH (1) · Colorado State University (1) · Mayo Clinic (1) · Nexira (1) · Swiss Federal Institute of Technology (1) · University of Minnesota (1) · University of Science and Technology, Yemen (1)
Sudan (8) · Canada (3) · Egypt (3) · United States (3) · Germany (2) · Switzerland (1) · United Arab Emirates (1)
Imad M Fdl-Elmula, PhD (2) · Ahmed H. Samaha, BSc (1) · Alnour Alagib, MBBS,MD,MRCP (1) · Amal M Saeed, MBBS,PhD (1) · Amal M Saeed, PhD (1) · Andrea M Haqq, MD, MHS (1) · Donna Z Bliss, phD (1) · Eytan Wine, MD, PhD (1) · Fatima Elhaj, PhD (1) · Isabelle Herter-Aeberli, PhD (1) · Justin Ezekowitz, MBBCh (1) · Lamis AA Kaddam, MSc (1) · Merna M. AbouKhatwa, BSc (1) · Moawia M Mukhtar, PhD (1)
PMID 28331623, PMID 32328307, PMID 15269196, PMID 17999333, PMID 19479191, PMID 23241359, PMID 23383316, PMID 24022265, PMID 26719803, PMID 28589039, PMID 30112005, PMID 30956961, PMID 31316836, PMID 32188508, PMID 32891160, PMID 33435475, PMID 33596993, PMID 33896052, PMID 35015879, PMID 35208961, PMID 35631293, PMID 36092515, PMID 36671523, PMID 3692386, PMID 37870148, PMID 37876886, PMID 40637175, PMID 6683227
R01NR007756 (1)