20 completed, 10 recruiting, 10 unknown, 4 not yet recruiting. 20 Not applicable, 18 Phase 2, 6 Phase 1, 3 Phase 4, 2 Phase 3.
Follow Cancer Cachexia: new trials by email Literature Review of Cancer Cachexia trials Research Report on Cancer Cachexia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Targeting Muscle-Bone Crosstalk Through Physical Therapy in Cancer Cachexia Structured Physical Therapy Exercise Program - Cancer Cachexia, Sarcopenia | Not applicable | Not yet recruiting | Pharos University in Alexandria | 40 | 2026-10-29 | 2026-09-08 |
| Benefits of Nutritional Supplement in Cancer Care Nutrition supplement, Digital Health App Monitoring, Individualized Dietitian Consultation - Nutritional Deterioration, Malignant Solid Tumor | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 100 | 2026-10-07 | 2026-10-09 |
| The First in Human Study of QLS2319 in Healthy Subjects and Cancer Cachexia QLS2319, Placebo - Cancer Cachexia, Cancer Cachexia Syndrome | Phase 1 / Phase 2 | Recruiting | Qilu Pharmaceutical Co., Ltd. | 88 | 2026-09-16 | 2026-09-25 |
| Cachexia and Gut Microbiota in Patients With Breast Cancer Receiving Home Care Probiotic Mixture, Placebo - Breast Cancer, Cancer Cachexia | Not applicable | Not yet recruiting | Fondazione ANT Franco Pannuti ETS | 140 | 2026-06-01 | 2026-06-17 |
| An Phase I/IIa Clinical Study to Evaluate the Safety/Tolerability, Pharmacokinetics and Preliminary Efficacy of INB301 Injection in Patients With Cancer Cachexia INB301 Injection - Cancer Cachexia | Phase 1 / Phase 2 | Not yet recruiting | Yunnan Baiyao Group Co., Ltd. | 146 | 2026-05-01 | 2026-05-13 |
| Effects of Dietary Supplementation With omega3-fatty Acids (Fish Oil) and Progressive Resistance Training on Skeletal Muscle Status in Gynaecological, Gastrointestinal and Urological Cancer Patients Omega 3 FA (Fish Oil), Training, Corn Oil Placebo, 4 capsules/day for 12 weeks - Cancer Cachexia, Omega 3 | Not applicable | Recruiting | University of Erlangen-Nürnberg Medical School | 288 | 2026-01-01 | 2026-06-11 |
| To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GB18 Injection in Healthy Participants GB18 injection, Placebo - Cancer Cachexia (CC), Cancer Cachexia | Phase 1 | Recruiting | Shenzhen Kexing Pharmaceutical Co., Ltd. | 36 | 2025-10-28 | 2025-11-19 |
| A First-in-Human Study of FID-022 in Solid Tumor Patients Baseline Lifestyle and Symptom Assessment, Extended Lifestyle Monitoring, Feasibility Survey - Pancreatic Cancer, Cancer Cachexia | Recruiting | H. Lee Moffitt Cancer Center and Research Institute | 120 | 2025-10-08 | 2026-01-28 | |
| Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder Psilocybin therapy - Adjustment Disorder, Adjustment Disorder With Anxious Mood | Phase 2 | Recruiting | Psyence Australia Pty Ltd | 87 | 2025-10-01 | 2026-03-03 |
| An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia. NGM120 Q4W, NGM120 Q8W, Placebo given - Colorectal Cancer, CRC (Colorectal Cancer) | Phase 2 | Recruiting | NGM Biopharmaceuticals, Inc | 136 | 2025-06-25 | 2026-04-01 |
| A Phase I Study to Evaluate GFS202A in Advanced Solid Tumor Patients With Pre-cachexia or Cachexia GFS202A injection - Cancer Cachexia | Phase 1 | Recruiting | Genfleet Therapeutics (Shanghai) Inc. | 36 | 2025-04-24 | 2025-06-05 |
| A Study of JMT203 in Patients With Cancer Cachexia JMT203 Injection - Non Small Cell Lung Cancer, Pancreatic Cancer | Phase 1 / Phase 2 | Recruiting | Shanghai JMT-Bio Inc. | 307 | 2024-05-15 | 2026-05-22 |
| Exploratory Trial of SAT-003 in Cancer Cachexia Patients With Discontinued Chemotherapy SAT-003 - Cancer Cachexia | Not applicable | Completed | S-Alpha Therapeutics, Inc. | 15 | 2023-07-11 | 2025-07-17 |
| Physical Training for Elderly Cancer Patients With Cachexia Physical training - Geriatric Assessment, Cancer | Not applicable | Active not recruiting | National Cheng-Kung University Hospital | 23 | 2023-07-05 | 2025-05-21 |
| A First in Human Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics Effects of OC514 OC514 (Low dose), OC514 (Mid dose), OC514 (High dose) - Cancer Cachexia | Phase 1 | Completed | Oncocross Australia Pty Ltd. | 23 | 2022-03-03 | 2023-03-20 |
| Nutrition Education and Quality of Life in Cancer Cachexia nutrition education - Cancer Cachexia | Not applicable | Unknown | Ordu University | 80 | 2022-03-01 | 2022-03-02 |
| Structural Characteristics of Trunk and Limb Muscles in Cachectic Colorectal Cancer Patients Minimal invasive fine needle muscle biopsies - Colorectal Cancer, Cancer Cachexia | Recruiting | Hasselt University | 60 | 2022-01-23 | 2025-09-09 | |
| EXPLORING the IMPACT of SUPERVISED PHYSICAL ACTIVITY INTERVENTION on CACHECTIC CANCER PATIENTS: a PRELIMINARY STUDY Adapted Physical Activity - Cancer Cachexia | Not applicable | Completed | University of Rennes 2 | 23 | 2020-11-01 | 2024-10-21 |
| The Effect of Curcumin for Treatment of Cancer Anorexia-Cachexia Syndrome in Patients With Stage III-IV of Head and Neck Cancer Curcumin, Placebo - Cancer Cachexia, Head and Neck Cancer | Phase 2 | Completed | Phramongkutklao College of Medicine and Hospital | 20 | 2020-02-13 | 2023-03-28 |
| Effect of Gene Polymorphisms on the Pathogenesis of Cancer Cachexia Pharmacogenetic testing - Cancer Cachexia | Unknown | Cairo University | 150 | 2019-06-20 | 2019-11-12 |
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Neoplasms (14) · Cachexia (8) · Weight Loss (6) · Pancreatic Neoplasms (5) · Anorexia (4) · Motor Activity (4) · Muscular Atrophy (4) · Colorectal Neoplasms (3) · Inflammation (3) · Breast Neoplasms (2) · Fatigue (2) · Head and Neck Neoplasms (2) · Hyperphagia (2) · Muscle Weakness (2) · Adjustment Disorders (1)
Pathological Conditions, Signs and Symptoms (20) · Signs and Symptoms (19) · Body Weight (13) · Body Weight Changes (13) · Neoplasms by Site (12) · Neoplasms (11) · Digestive System Diseases (9) · Digestive System Neoplasms (9) · Thinness (8) · Pathologic Processes (7) · Weight Loss (7) · Signs and Symptoms, Digestive (6) · Atrophy (5) · Endocrine Gland Neoplasms (5) · Endocrine System Diseases (5)
Eicosapentaenoic Acid (2) · Fish Oils (2) · Parenteral Nutrition (2) · kang-lai-te (2) · Absorptiometry, Photon (1) · Acupuncture Therapy (1) · Capsules (1) · Carnitine (1) · Control Groups (1) · Curcumin (1) · Data Collection (1) · Dietary Supplements (1) · Docosahexaenoic Acids (1) · EOM613 (1) · High-Intensity Interval Training (1)
University of Erlangen-Nürnberg Medical School (5) · H. Lee Moffitt Cancer Center and Research Institute (3) · Helsinn Therapeutics (U.S.), Inc (3) · Zhejiang Kanglaite Pharmaceutical Co.Ltd (2) · Akamis Bio (1) · Azienda USL Reggio Emilia - IRCCS (1) · CONKO-Studiengruppe (1) · Cairo University (1) · Cannabics Pharmaceuticals Inc. (1) · David Travis Thomas (1) · Fondazione ANT Franco Pannuti ETS (1) · Garcia, Jose M., MD, PhD (1) · General Hospital Groeninge (1) · Genfleet Therapeutics (Shanghai) Inc. (1) · Göteborg University (1)
United States (11) · China (8) · Germany (7) · Australia (3) · Belgium (2) · Denmark (2) · Italy (2) · South Korea (2) · Taiwan (2) · Canada (1) · Egypt (1) · France (1) · Georgia (1) · India (1) · Israel (1)
William Polvino, MD (3) · Dejan Reljic, Dr. (2) · Adrian S. Dobs, MD, MHS (1) · Alessandro Laviano, MD (1) · Andrew M Scott, MD (1) · Chaoting Zhao, MD (1) · Chih Chieh Yen, MD (1) · Clive Ward-Able (1) · Dalyong Kim, M.D., Ph.D (1) · Enrico Ruggeri, Medicine (1) · Ghulam Rasool, PhD (1) · Gil Bar-Sela, Md (1) · Haiou Luo, PhD (1)
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P50AT000437 (1)