194 completed, 48 recruiting, 48 unknown, 25 terminated. 133 Not applicable, 51 Phase 2, 38 Phase 3, 28 Phase 1, 5 Phase 4.
Follow Thinness: new trials by email Literature Review of Thinness trials Research Report on Thinness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) Endothelial cell collection - Obesity and Obesity-related Medical Conditions, Diabetes | Recruiting | Bettina Mittendorfer | 100 | 2027-01-01 | 2026-05-07 | |
| A Phase II Clinical Study Evaluating the Efficacy and Safety of SXRN Injection in Patients With Cancer Cachexia SXRN Injection, Placebo - Cachexia-Anorexia Syndrome, Cachexia; Cancer | Phase 2 | Not yet recruiting | Jiangsu Guiqiong Pharmaceutical Co., Ltd. | 96 | 2026-12-01 | 2026-10-26 |
| Building Opportunities for Nurturing Care to Enhance Child Development in Eastern and Southern Africa Friendship Bench, Infant and Young Child Feeding (IYCF) Curriculum, Play-Based Curriculum - Neurodevelopment, Child Growth | Not applicable | Not yet recruiting | University of Washington | 1260 | 2026-11-01 | 2026-03-03 |
| Master Protocol for the Study of Rilogrotug for the Treatment of Weight Loss and Anorexia in Patients With Cancer Cachexia and mCRC or mNSCLC Rilogrotug, Placebo - Cachexia; Cancer, Cachexia | Phase 2 / Phase 3 | Not yet recruiting | AVEO Pharmaceuticals, Inc. | 950 | 2026-11-01 | 2026-10-28 |
| A Study to Learn About the Study Medicine Called Ponsegromab in Adults With Lung Cancer-Associated Significant Body Weight Loss ponsegromab, placebo - Non-small Cell Lung Cancer (NSCLC), Cachexia | Phase 1 | Not yet recruiting | Pfizer | 80 | 2026-10-23 | 2026-09-25 |
| Building Healthy Food Environment in Schools: Evaluating Co-created Interventions in Low Resource Settings. #BetterNutrition4Adolescent Multicomponent school nutrition intervention, Usual nutrition program - Overweight Adolescents, Underweight | Not applicable | Not yet recruiting | Norwegian University of Science and Technology | 2600 | 2026-10-01 | 2026-01-12 |
| SHIFT-TB: Nutrition Intervention and Evaluation Community-Based Nutrition Intervention - Underweight, Overweight and Obesity | Not applicable | Not yet recruiting | National University of Singapore | 700 | 2026-10-01 | 2026-10-27 |
| Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+] - Neurodevelopment Outcome, Linear Growth | Phase 3 | Recruiting | Johns Hopkins Bloomberg School of Public Health | 3000 | 2026-09-27 | 2026-10-09 |
| A Multimodal Integrated Intervention for Kidney Cachexia Multi-Modal Integrated Intervention Combining Exercise, Anti-inflammatory & Dietary Advice (MMIEAD) - Cachexia, CKD | Not applicable | Recruiting | Queen's University, Belfast | 40 | 2026-09-01 | 2026-08-26 |
| Hospital-Based Prospective Cohort of Malnutrition Under 6-Month Study (HOSPIC-6-Study) Not applicable- observational study - Malnutrition, Infant, Malnutrition | Recruiting | Universitas Indonesia | 1780 | 2026-08-28 | 2026-10-20 | |
| Using Strength Tests to Better Understand How Pancreatic Cancer Affects Muscle Mass and Quality of Life Hand grip strength assessments using a dynamometer - Pancreatic Ductal Adenocarcinoma (PDAC), Hand Grip Strength | Not applicable | Recruiting | British Columbia Cancer Agency | 50 | 2026-08-13 | 2026-09-15 |
| Effectiveness of Positive Deviance/Hearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh PD/Hearth is a behavioral change program that teaches caregivers how to cook and feed their children. A nutrient-dense meal using local ingredients will be fed to children during Hearth sessions., Standard of Care (Investigator Selected) - Moderate Acute Malnutrition (MAM), Undernutrition | Not applicable | Enrolling by invitation | World Vision US | 400 | 2026-07-08 | 2026-10-21 |
| Nanocrystalline Megestrol Acetate Versus Placebo for Anorexia in Patients With Unresectable Hepatocellular Carcinoma Receiving TACE Combined With Targeted and Immunotherapy Nanocrystalline megestrol acetate, Placebo - Hepatocellular Carcinoma (HCC), Cachexia | Phase 2 | Not yet recruiting | Nanfang Hospital, Southern Medical University | 88 | 2026-06-22 | 2026-05-04 |
| A Phase I Clinical Study to Evaluate the Efficacy and Safety of GB18 Injection in Patients With Tumor Cachexia GB18 - Cachexia; Cancer | Phase 1 | Recruiting | Kexing Biopharm Co., Ltd. | 18 | 2026-06-10 | 2026-06-12 |
| Phase 2 Cachexia Clinical Trial to Evaluate the Efficacy and Safety of ASCA101 Active Comparator, ASCA101 24.32mg/kg, ASCA101 32.43mg/kg - Cachexia; Cancer | Phase 2 | Recruiting | MetaFines | 135 | 2026-05-08 | 2026-06-17 |
| Regular Growth Monitoring (RGM) of Young Children in Guinea-Bissau Regular Growth Monitoring (RGM) by Community Health Agents - Severe Acute Malnutrition, Moderate Acute Malnutrition (MAM) | Not applicable | Active not recruiting | Trustees of Dartmouth College | 400 | 2026-05-05 | 2026-07-15 |
| Telemedicine Nutritional Counseling for Cancer Cachexia in Pakistan Telemedicine-Delivered Nutritional Counseling, Standard In-Person Nutritional Counseling - Cachexia; Cancer; Sarcopenia | Not applicable | Active not recruiting | King Edward Medical University | 80 | 2026-05-01 | 2026-06-08 |
| Intestinal Microbiota Transplantation for Treating Advanced Tumor Cachexia FMT capsule - Cachexia; Cancer, Fecal Microbiota Transplantation (FMT) | Phase 2 | Not yet recruiting | Hua Jiang | 66 | 2026-05-01 | 2026-04-16 |
| A Clinical Study of Nanocrystalline Megestrol Acetate in Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer Nanocrystalline Megestrol Acetate Oral Suspension - Locally Advanced Cervical Cancer, Cachexia | Phase 1 | Recruiting | Second Xiangya Hospital of Central South University | 88 | 2026-04-30 | 2026-04-24 |
| Study of the Safety and Efficacy of DS010 in Patients With Cancer Cachexia DS010 injection - Cancer, Cachexia | Phase 1 / Phase 2 | Not yet recruiting | Dartsbio Pharmaceuticals Ltd. | 58 | 2026-04-30 | 2026-04-15 |
Showing 20 of 354. Sign in to see all of them.
Cachexia (302) · Neoplasms (80) · Malnutrition (57) · Anorexia (44) · Growth Disorders (36) · Weight Loss (33) · Pancreatic Neoplasms (29) · Carcinoma, Non-Small-Cell Lung (28) · Sarcopenia (24) · Motor Activity (18) · Obesity (18) · Severe Acute Malnutrition (17) · Lung Neoplasms (16) · Child Nutrition Disorders (14)
Pathological Conditions, Signs and Symptoms (354) · Signs and Symptoms (354) · Body Weight (345) · Body Weight Changes (298) · Weight Loss (271) · Nutritional and Metabolic Diseases (108) · Nutrition Disorders (99) · Neoplasms by Site (90) · Pathologic Processes (82) · Neoplasms (73) · Digestive System Diseases (56) · Respiratory Tract Diseases (56) · Signs and Symptoms, Digestive (55) · Lung Diseases (54)
Megestrol Acetate (14) · Exercise (8) · Blood Specimen Collection (6) · Standard of Care (6) · Nutrition Assessment (4) · Olanzapine (4) · GSK2881078 (3) · Ibuprofen (3) · Infliximab (3) · Amoxicillin (2) · Cholecalciferol (2) · Counseling (2) · Cyproheptadine (2) · Diet Therapy (2) · Dietary Supplements (2)
International Food Policy Research Institute (8) · National Taiwan University Hospital (6) · Norwegian University of Science and Technology (6) · Pfizer (6) · University of Erlangen-Nürnberg Medical School (6) · Aga Khan University (5) · GlaxoSmithKline (5) · Johns Hopkins Bloomberg School of Public Health (5) · M.D. Anderson Cancer Center (5) · Novartis Pharmaceuticals (5) · The University of Texas Medical Branch, Galveston (5) · Helsinn Therapeutics (U.S.), Inc (4) · Maastricht University Medical Center (4) · Rabin Medical Center (4) · University Hospital, Clermont-Ferrand (4)
United States (98) · United Kingdom (26) · Germany (24) · China (23) · France (19) · Canada (18) · India (14) · Poland (14) · Italy (13) · Pakistan (13) · Taiwan (12) · Belgium (11) · Norway (10) · Bangladesh (9) · Brazil (9)
Aminah Jatoi, MD (4) · Moshe Phillip, Prof (3) · Andrew Hendifar, MD (2) · Annemie Schols, PhD (2) · Dejan Reljic, Dr. (2) · Elodie Becquey, PhD (2) · Ihab Tewfik, PhD (2) · Lieven Huybregts, PhD (2) · Lynn D Kramer, MD (2) · Mark J Manary, MD (2) · Melinda Sheffield-Moore, Ph.D. (2)
PMID 28472437, PMID 26906526, PMID 39992021, PMID 42665333, PMID 10371570, PMID 11786587, PMID 12457271, PMID 12648025, PMID 14602249, PMID 15197210, PMID 15778874, PMID 15857739, PMID 16314085, PMID 16317825, PMID 1632474, PMID 16376734, PMID 16408219, PMID 1666930, PMID 16843954, PMID 16849753, PMID 17566383, PMID 17589370, PMID 17662149, PMID 17674351, PMID 18257397, PMID 18293016, PMID 18402303, PMID 18728826, PMID 18989154, PMID 19342610, PMID 19587829, PMID 19593244, PMID 19665818, PMID 19883531, PMID 19896326, PMID 19959405, PMID 20060626, PMID 20076976, PMID 20392703, PMID 20937647, PMID 21093718, PMID 21296615, PMID 21343383, PMID 21448087, PMID 21475692, PMID 21615299, PMID 21627690, PMID 22076835, PMID 22419719, PMID 22665599
2018 (2), R01CA127971 (2), U10CA081920 (2), 2017 (1), 2023 (1), 2025 (1), K01TW009987 (1), P30CA012197 (1), P30CA043703 (1), P30CA069533 (1), R01AR060209 (1), R01HD103642 (1), R33HD110150 (1), R33MH121549 (1), R43AR054993 (1)