4 recruiting, 1 completed, 1 not yet recruiting. 6 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Recruiting 4, Completed 1, Not yet recruiting 1 |
| Phase 2 | 3 | Recruiting 2, Not yet recruiting 1 |
Follow Cancer Cachexia: new trials by email Literature Review of Cancer Cachexia trials Research Report on Cancer Cachexia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The First in Human Study of QLS2319 in Healthy Subjects and Cancer Cachexia QLS2319, Placebo - Cancer Cachexia, Cancer Cachexia Syndrome | Phase 1 / Phase 2 | Recruiting | Qilu Pharmaceutical Co., Ltd. | 88 | 2026-09-16 | 2026-09-25 |
| An Phase I/IIa Clinical Study to Evaluate the Safety/Tolerability, Pharmacokinetics and Preliminary Efficacy of INB301 Injection in Patients With Cancer Cachexia INB301 Injection - Cancer Cachexia | Phase 1 / Phase 2 | Not yet recruiting | Yunnan Baiyao Group Co., Ltd. | 146 | 2026-05-01 | 2026-05-13 |
| To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GB18 Injection in Healthy Participants GB18 injection, Placebo - Cancer Cachexia (CC), Cancer Cachexia | Phase 1 | Recruiting | Shenzhen Kexing Pharmaceutical Co., Ltd. | 36 | 2025-10-28 | 2025-11-19 |
| A Phase I Study to Evaluate GFS202A in Advanced Solid Tumor Patients With Pre-cachexia or Cachexia GFS202A injection - Cancer Cachexia | Phase 1 | Recruiting | Genfleet Therapeutics (Shanghai) Inc. | 36 | 2025-04-24 | 2025-06-05 |
| A Study of JMT203 in Patients With Cancer Cachexia JMT203 Injection - Non Small Cell Lung Cancer, Pancreatic Cancer | Phase 1 / Phase 2 | Recruiting | Shanghai JMT-Bio Inc. | 307 | 2024-05-15 | 2026-05-22 |
| A First in Human Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics Effects of OC514 OC514 (Low dose), OC514 (Mid dose), OC514 (High dose) - Cancer Cachexia | Phase 1 | Completed | Oncocross Australia Pty Ltd. | 23 | 2022-03-03 | 2023-03-20 |
Cachexia (1) · Carcinoma, Non-Small-Cell Lung (1) · Neoplasms (1) · Pancreatic Neoplasms (1)
Body Weight (1) · Body Weight Changes (1) · Bronchial Neoplasms (1) · Carcinoma, Bronchogenic (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Endocrine Gland Neoplasms (1) · Endocrine System Diseases (1) · Lung Diseases (1) · Lung Neoplasms (1) · Neoplasms (1) · Neoplasms by Site (1) · Pancreatic Diseases (1) · Pathological Conditions, Signs and Symptoms (1) · Respiratory Tract Diseases (1)
alkaloid GB18 (1)
Genfleet Therapeutics (Shanghai) Inc. (1) · Oncocross Australia Pty Ltd. (1) · Qilu Pharmaceutical Co., Ltd. (1) · Shanghai JMT-Bio Inc. (1) · Shenzhen Kexing Pharmaceutical Co., Ltd. (1) · Yunnan Baiyao Group Co., Ltd. (1)
China (5) · Australia (1)
Li Zhang, MD (1) · Ofer Gonen, Dr. (1)