85 completed. 85 Phase 3, 13 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 85 | Completed 85 |
| Phase 2 | 13 | Completed 13 |
Follow Bronchiolitis: new trials by email Literature Review of Bronchiolitis trials Research Report on Bronchiolitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hyaluronic Acid Mouthwash as Adjunct Hyaluoric acid mouthwash, Chlorhexidine 0,12% - Gingivitis; Chronic | Phase 3 | Completed | Cairo University | 16 | 2025-02-01 | 2026-01-26 |
| Efficacy of Vitamin D Supplementation for Children With Bronchiolitis Vitamin D3 - Bronchiolitis | Phase 2 / Phase 3 | Completed | Sohag University | 146 | 2023-04-01 | 2024-10-29 |
| Nebulised 3% Hypertonic Saline in Infants With Acute Bronchiolitis 3% Sodium Chloride, Standard care - Acute Bronchiolitis | Phase 2 / Phase 3 | Completed | Can Tho University of Medicine and Pharmacy | 140 | 2022-06-01 | 2024-08-16 |
| Nintedanib in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome Grade 0p-1-2 Nintedanib, Placebo - Lung-transplant Recipients | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 58 | 2019-10-30 | 2025-09-08 |
| Study of Efficacy and Safety of Erenumab in Adult Chronic Migraine Patients Erenumab, Placebo - Migraine | Phase 3 | Completed | Novartis Pharmaceuticals | 557 | 2019-08-26 | 2025-10-16 |
| Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) Liposomal Cyclosporine A, standard of care - Bronchiolitis Obliterans, Chronic Rejection of Lung Transplant | Phase 3 | Completed | Zambon SpA | 62 | 2019-03-26 | 2025-10-27 |
| Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Double Lung Transplant (BOSTON-2) Liposomal Cyclosporine A, Standard of Care - Bronchiolitis Obliterans, Chronic Rejection of Lung Transplant | Phase 3 | Completed | Zambon SpA | 169 | 2019-03-26 | 2026-02-10 |
| Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone Study Oral dexamethasone, Nebulized Epinephrine, Oral placebo - Bronchiolitis | Phase 3 | Completed | Children's Hospital of Eastern Ontario | 864 | 2018-12-13 | 2025-07-28 |
| Efficacy and Safety of Tx360® Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine Tx360 - Headache, Migraine | Phase 3 | Completed | Tian Medical Inc. | 174 | 2017-09-20 | 2024-01-05 |
| A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3) Ruxolitinib, Extracorporeal photopheresis (ECP), Low-dose methotrexate (MTX) - Graft-versus-host Disease (GVHD) | Phase 3 | Completed | Incyte Corporation | 330 | 2017-06-29 | 2025-08-12 |
| Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD) ibrutinib, Placebo, Prednisone - Chronic Graft Versus Host Disease | Phase 3 | Completed | Pharmacyclics LLC. | 193 | 2017-05-11 | 2023-03-30 |
| Evaluation of the Efficacy Safety and Tolerability of Nitric Oxide Given Intermittently Via Inhalation to Subjects With Bronchiolitis Nitric Oxide, Supportive treatment - Bronchiolitis | Phase 3 | Completed | Beyond Air Inc. | 69 | 2017-03-05 | 2019-07-09 |
| A Study of of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus (HCV) Genotype 5 or 6 Infection Glecaprevir/Pibrentasvir - Hepatitis C Virus (HCV) | Phase 3 | Completed | AbbVie | 84 | 2017-01-25 | 2021-07-30 |
| Azithromycin to Prevent Wheezing Following Severe RSV Bronchiolitis-II Oral azithromycin, Placebo - Respiratory Syncytial Virus, Bronchiolitis | Phase 2 / Phase 3 | Completed | Washington University School of Medicine | 200 | 2016-11-01 | 2022-06-07 |
| Safety and Efficacy of SOF/VEL/VOX FDC for 12 Weeks and SOF/VEL for 12 Weeks in DAA-Experienced Adults With Chronic HCV Infection Who Have Not Received an NS5A Inhibitor SOF/VEL/VOX, SOF/VEL - Hepatitis C Virus Infection | Phase 3 | Completed | Gilead Sciences | 333 | 2015-12-23 | 2019-03-05 |
| Safety and Efficacy of SOF/VEL/VOX FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis SOF/VEL/VOX, SOF/VEL - Hepatitis C Virus Infection | Phase 3 | Completed | Gilead Sciences | 220 | 2015-12-23 | 2019-03-05 |
| Calcineurin Inhibitor-Free Interventions BMT CTN 1301 for Prevention of Graft-versus-Host Disease (BMT CTN 1301) Unmanipulated Bone Marrow Graft with Tacrolimus/Methotrexate, Mobilized CD34-selected Peripheral Blood Stem Cell graft, Unmanipulated Bone Marrow Graft with Cyclophosphamide - Acute Leukemia, Myelodysplasia | Phase 3 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 346 | 2015-08-01 | 2023-03-07 |
| Antibiotics In Modic Changes Amoxicillin (Amoksicillintrihydrat), Placebo - Low Back Pain, Modic Changes Type I or II Seen on MRI | Phase 3 | Completed | Oslo University Hospital | 180 | 2015-06-01 | 2021-09-27 |
| Study of Efficacy and Safety of Canakinumab in Japanese Patients With SJIA Canakinumab - Systemic Juvenile Idiopathic Arthritis | Phase 3 | Completed | Novartis Pharmaceuticals | 19 | 2015-05-07 | 2019-09-13 |
| European Trial of Pirfenidone in BOS, A European Multi-center Study Pirfenidone, Placebo - Disorder Related to Lung Transplantation, CLAD, Bronchiolitis Obliterans | Phase 2 / Phase 3 | Completed | Copenhagen University Hospital, Rigshospitalet | 90 | 2015-05-01 | 2020-01-18 |
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Bronchiolitis Obliterans Syndrome (55) · Bronchiolitis Obliterans (7) · Leukemia (6) · Lymphoma, Follicular (6) · Psoriasis (6) · Migraine Disorders (5) · Pruritus (5) · Constipation (4) · Headache (4) · Hepatitis C (4) · Low Back Pain (4) · Pulmonary Disease, Chronic Obstructive (4) · Arthralgia (3) · Arthritis, Juvenile (3)
Lung Diseases (85) · Bronchial Diseases (84) · Lung Diseases, Obstructive (84) · Respiratory Tract Diseases (83) · Bronchitis (82) · Immune System Diseases (56) · Organizing Pneumonia (55) · Bronchiolitis Obliterans (54) · Graft vs Host Disease (53) · Pathological Conditions, Signs and Symptoms (43) · Infections (36) · Signs and Symptoms (29) · Respiratory Tract Infections (24) · Neurologic Manifestations (15)
Sodium Chloride (6) · tofacitinib (6) · Imatinib Mesylate (5) · Saline Solution (4) · Standard of Care (4) · Saline Solution, Hypertonic (3) · Tacrolimus (3) · Topiramate (3) · canakinumab (3) · ibrutinib (3) · Cyclosporine (2) · Dexamethasone (2) · Everolimus (2) · Methotrexate (2) · Mycophenolic Acid (2)
Pfizer (7) · Novartis Pharmaceuticals (6) · Baqiyatallah Medical Sciences University (4) · Assistance Publique - Hôpitaux de Paris (3) · Gilead Sciences (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3) · AstraZeneca (2) · GlaxoSmithKline (2) · International Centre for Diarrhoeal Disease Research, Bangladesh (2) · Mundipharma Research GmbH & Co KG (2) · Pharmacyclics LLC. (2) · Zambon SpA (2) · APT Pharmaceuticals, Inc. (1) · AbbVie (1) · Atlantia Food Clinical Trials (1)
United States (27) · Germany (21) · France (19) · Canada (18) · United Kingdom (16) · Spain (15) · Belgium (14) · Australia (12) · Poland (12) · Hungary (10) · Italy (10) · Austria (9) · Denmark (9) · Israel (9) · Netherlands (9)
Mary Horowitz, MD (2) · Mostafa Ghanei, MD (2) · Paola Castellani, MD (2) · Alan Jackson, MB, BS (1) · Allan Glanville, MD, PhD (1) · Alun George, MA MBBS, DRCOG, DCH, MRCGP (1) · Alyn Morice, BA(Hons) MB.B.Chir MA FRCP (1) · Amy Plint, MSc, MD (1) · Andre M Beer, MD, PhD (1)
PMID 32816215, PMID 26149717, PMID 28396102, PMID 12563043, PMID 15121942, PMID 16352625, PMID 17300356, PMID 18668692, PMID 19860762, PMID 21183326, PMID 21943218, PMID 22147778, PMID 22645182, PMID 23380743, PMID 23668548, PMID 24139233, PMID 24268590, PMID 24382580, PMID 24410959, PMID 24521787, PMID 24862623, PMID 24881631, PMID 24928639, PMID 25038354, PMID 25404569, PMID 25418186, PMID 25583164, PMID 25788164, PMID 26051365, PMID 26182309, PMID 26233481, PMID 26278222, PMID 26286532, PMID 26743093, PMID 26784000, PMID 26871197, PMID 27271195, PMID 27538247, PMID 27724916, PMID 27890073, PMID 28373262, PMID 28390869, PMID 28558833, PMID 28558978, PMID 28564569, PMID 28586918, PMID 28726086, PMID 28751001, PMID 28751558, PMID 28839984
2018 (3), 2014 (2), 2015 (2), 2016 (2), U01HL069294 (2), 2008 (1), U01AT001908 (1), U01IP000127 (1), U24CA076518 (1)