134 completed. 134 Phase 2, 34 Phase 1, 13 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 134 | Completed 134 |
| Phase 1 | 34 | Completed 34 |
| Phase 3 | 13 | Completed 13 |
Follow Bronchiolitis: new trials by email Literature Review of Bronchiolitis trials Research Report on Bronchiolitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection RSP-1502, Tobramycin inhalation solution - Cystic Fibrosis Lung, Respiratory Infections, Recurrent, Chronic | Phase 1 / Phase 2 | Completed | Respirion Pharmaceuticals Pty Ltd | 71 | 2024-04-01 | 2026-06-25 |
| Efficacy of Vitamin D Supplementation for Children With Bronchiolitis Vitamin D3 - Bronchiolitis | Phase 2 / Phase 3 | Completed | Sohag University | 146 | 2023-04-01 | 2024-10-29 |
| Nebulised 3% Hypertonic Saline in Infants With Acute Bronchiolitis 3% Sodium Chloride, Standard care - Acute Bronchiolitis | Phase 2 / Phase 3 | Completed | Can Tho University of Medicine and Pharmacy | 140 | 2022-06-01 | 2024-08-16 |
| Extended Treatment and Follow-up of Subjects Treated With Belumosudil in Study KD025-208 or Study KD025-213 Belumosudil 200 mg QD, Belumosudil 200 mg BID, Belumosudil 400 mg QD - Chronic Graft-versus-host-disease | Phase 2 | Completed | Kadmon, a Sanofi Company | 23 | 2022-02-23 | 2025-05-02 |
| Bacterial Lysate In Preventing Asthma Bacterial Lysate - Respiratory Tract Infections, Pediatric Respiratory Diseases | Phase 2 | Completed | Queen Mary University of London | 173 | 2022-01-12 | 2026-05-19 |
| Study of Efficacy and Safety of CML-CP Patients Treated With Asciminib Versus Best Available Therapy, Previously Treated With 2 or More Tyrosine Kinase Inhibitors asciminib, best available treatment - Leukemia, Chronic Myelogenous | Phase 2 | Completed | Novartis Pharmaceuticals | 84 | 2021-12-06 | 2025-04-18 |
| Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease Ibrutinib, ECG, PFT's - Chronic GVHD | Phase 2 | Completed | National Cancer Institute (NCI) | 10 | 2021-05-10 | 2026-01-23 |
| Efficacy and Safety of BN101 in Subjects With Chronic Graft Versus Host Disease (cGVHD) BN101 - GVHD, Chronic | Phase 2 | Completed | BioNova Pharmaceuticals (Shanghai) LTD. | 30 | 2021-04-27 | 2024-01-17 |
| Allogeneic Platelet Lysate Eye Drops for the Treatment of Severe Chronic Ocular Graft-versus-host Disease Allogeneic platelet lysate eye drops - Ocular Graft-versus-host Disease | Phase 2 | Completed | St. Petersburg State Pavlov Medical University | 38 | 2021-04-01 | 2024-12-04 |
| Dexamethasone Solution and Dexamethasone in Mucolox™ dexamethasone 0.5mg/5ml solution, dexamethasone 0.5mg/5ml solution in Mucolox™ - Oral Lichen Planus, Mucous Membrane Pemphigoid | Phase 2 | Completed | University of California, San Francisco | 29 | 2020-12-26 | 2023-12-15 |
| Efficacy of Dupilumab for Patients With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) dupilumab, placebo - Chronic Sinusitis | Phase 2 | Completed | Johns Hopkins University | 33 | 2020-10-15 | 2025-11-03 |
| Hp129 Xenon Imaging and BOS in Lung Transplantation Hp 129Xenon - Bronchiolitis Obliterans | Phase 1 / Phase 2 | Completed | Children's Hospital Medical Center, Cincinnati | 3 | 2020-09-09 | 2026-09-18 |
| Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Severe Chronic Graft vs. Host Disease After Allogeneic Stem Cell Transplant INC424 - Graft vs Host Disease | Phase 2 | Completed | Novartis Pharmaceuticals | 46 | 2020-05-20 | 2025-12-11 |
| A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy HB-adMSCs - Traumatic Brain Injury | Phase 1 / Phase 2 | Completed | Hope Biosciences LLC | 24 | 2020-01-01 | 2026-01-15 |
| Acalabrutinib in CLL and MCL Patients Subjected to Allogeneic Hematopoietic Stem Cell Transplantation (alloSCT) Acalabrutinib 2x100 MG Oral Capsule + alloSCT - Chronic Lymphocytic Leukemia, Chronic Graft-versus-host-disease | Phase 2 | Completed | Polish Lymphoma Research Group | 29 | 2019-08-19 | 2025-01-16 |
| Nintedanib in Patients With Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem Cell Transplantation Nintedanib - Bronchiolitis Obliterans Syndrome (BOS), Bronchiolitis Obliterans (BO) | Phase 2 | Completed | University Hospital, Basel, Switzerland | 20 | 2019-03-20 | 2026-10-27 |
| PT-CY With or Without Low-dose ATG for Lymphoid Malignancies Undergoing Allo-HSCT PT-CY-FK +/-ATG - GVHD, Acute | Phase 2 | Completed | Shanghai Jiao Tong University School of Medicine | 23 | 2019-01-01 | 2021-05-21 |
| Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD) Ibrutinib - Chronic Graft Versus Host Disease | Phase 1 / Phase 2 | Completed | Pharmacyclics LLC. | 59 | 2018-11-19 | 2025-10-21 |
| A Phase 1/2 Study to Evaluate Axatilimab in Participants With Active cGVHD axatilimab - Chronic Graft-versus-host-disease | Phase 1 / Phase 2 | Completed | Syndax Pharmaceuticals | 41 | 2018-11-01 | 2025-09-15 |
| Discontinuation or Continuation of Immunosuppressive Therapy in Participants With Chronic Graft Versus Host Disease Immunosuppressive Therapy, Survey Administration - Chronic Graft Versus Host Disease | Phase 2 | Completed | Fred Hutchinson Cancer Center | 21 | 2018-06-06 | 2021-06-23 |
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Bronchiolitis Obliterans Syndrome (107) · Graft vs Host Disease (15) · Bronchiolitis Obliterans (12) · Leukemia (12) · Leukemia, Lymphocytic, Chronic, B-Cell (9) · Pulmonary Disease, Chronic Obstructive (8) · Lymphoma, Follicular (6) · Hepatitis C (4) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (4) · Neoplasms (4) · Pain (4) · Psoriasis (4) · Respiration Disorders (4) · Constipation (3)
Bronchial Diseases (134) · Lung Diseases (134) · Respiratory Tract Diseases (133) · Bronchitis (132) · Lung Diseases, Obstructive (132) · Organizing Pneumonia (108) · Immune System Diseases (107) · Bronchiolitis Obliterans (105) · Graft vs Host Disease (94) · Pathological Conditions, Signs and Symptoms (50) · Pathologic Processes (34) · Infections (32) · Disease Attributes (30) · Chronic Disease (28)
Formoterol Fumarate (5) · montelukast (5) · N-((5-(methanesulfonyl)pyridin-2-yl)methyl)-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide (4) · Ribavirin (4) · Rituximab (4) · ibrutinib (4) · Azithromycin (3) · Cholecalciferol (3) · Fluticasone (3) · Prednisone (3) · Saline Solution, Hypertonic (3) · Sirolimus (3) · Sodium Chloride (3) · Tacrolimus (3) · Alemtuzumab (2)
AstraZeneca (6) · Novartis Pharmaceuticals (5) · Fred Hutchinson Cancer Center (4) · National Cancer Institute (NCI) (4) · Assistance Publique - Hôpitaux de Paris (3) · Dana-Farber Cancer Institute (3) · Dey (2) · Eli Lilly and Company (2) · Genta Incorporated (2) · Gilead Sciences (2) · H. Lee Moffitt Cancer Center and Research Institute (2) · MetrioPharm AG (2) · Mundipharma Research GmbH & Co KG (2) · National Heart, Lung, and Blood Institute (NHLBI) (2) · Organon and Co (2)
United States (70) · Canada (15) · Germany (14) · United Kingdom (13) · Spain (12) · Russia (10) · France (8) · Italy (8) · Australia (7) · Poland (7) · Czechia (6) · Japan (6) · Netherlands (5) · South Korea (5) · Taiwan (5)
Stephanie Lee (5) · Esther Garcia, MD (2) · Nicole J Gormley, M.D. (2) · Radmila Razlog, M.TechHom (2) · Steven Z Pavletic, M.D. (2) · Alan H Lau, Pharm.D. (1) · Aldo T Iacono, MD (1) · Alessandro Villa, DDS, PhD, MPH (1) · Allyson Gage, PhD (1) · Amandeep Salhotra, MD (1) · Anke Gauliard, MD (1)
PMID 24432712, PMID 25287629, PMID 34773261, PMID 36440464, PMID 16186597, PMID 18219306, PMID 18502835, PMID 19745067, PMID 21039672, PMID 21073773, PMID 21937568, PMID 22155140, PMID 22197578, PMID 22455413, PMID 22458939, PMID 23861248, PMID 23903014, PMID 24139233, PMID 24382580, PMID 24400934, PMID 24410959, PMID 24862623, PMID 24928639, PMID 24995488, PMID 25242558, PMID 25261839, PMID 25265132, PMID 25693783, PMID 25835160, PMID 26043724, PMID 26189353, PMID 26286532, PMID 26475726, PMID 26945226, PMID 27102120, PMID 27724916, PMID 28286262, PMID 28924018, PMID 29174754, PMID 29439971, PMID 29549175, PMID 29954931, PMID 30178528, PMID 30333224, PMID 30936057, PMID 31260802, PMID 31511239, PMID 31577874, PMID 32981857, PMID 33305842
P30CA015704 (4), 2009 (2), 2014 (2), 2015 (2), 2017 (2), 2018 (2), 2005 (1), 2016 (1), U01AT001908 (1), U01HL069294 (1), U24CA076518 (1), U54CA163438 (1)