63 completed, 12 recruiting, 12 terminated, 9 active not recruiting. 109 Phase 1, 56 Phase 2.
Follow Bronchiolitis: new trials by email Literature Review of Bronchiolitis trials Research Report on Bronchiolitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, TVAX-008, Placebo - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Grand Theravac Life Sciences (Hangzhou) Co., Ltd. | 105 | 2026-10-31 | 2026-10-27 |
| A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in Children 1mg /kg VIC-1911 - GVHD (Acute or Chronic) | Phase 1 | Recruiting | Shanghai Jiao Tong University School of Medicine | 9 | 2026-09-28 | 2026-10-20 |
| Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants Belumosudil - Chronic Graft Versus Host Disease | Phase 1 | Not yet recruiting | Sanofi | 58 | 2026-08-06 | 2026-07-24 |
| A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function. AHB-137 injection - Chronic Hepatitis B | Phase 1 | Recruiting | Ausper Biopharma Co., Ltd. | 32 | 2026-07-09 | 2026-07-29 |
| Ex Vivo-Expanded Regulatory T Cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic GVHD EVE-Treg - Graft Versus Host Disease (cGvHD) | Phase 1 | Recruiting | Sarah Nikiforow, MD | 21 | 2026-05-29 | 2026-10-29 |
| Evaluation of Belumosudil Whole Tablets vs. Crushed Tablets Pharmacokinetics in Patients Suffering From Chronic GvHD Belumosudil - Chronic Graft Versus Host Disease | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 8 | 2026-02-09 | 2026-08-27 |
| Brain State-dependent PCMS in Chronic Stroke Brain state-dependent paired corticomotoneuronal stimulation (PCMS) - Stroke | Phase 1 / Phase 2 | Not yet recruiting | University of Texas at Austin | 45 | 2026-01-01 | 2024-12-06 |
| A Study to Evaluate Adrixetinib (Q702) in Adults With Active Chronic Graft-Versus-Host Disease Adrixetinib - Chronic Graft-Versus-Host Disease | Phase 1 | Recruiting | Qurient Co., Ltd. | 18 | 2025-12-23 | 2025-12-30 |
| Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD Fostamatinib, Ruxolitinib - Chronic Graft Versus Host Disease | Phase 1 | Recruiting | Stefanie Sarantopoulos, MD, PhD. | 30 | 2025-10-29 | 2026-01-22 |
| A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury OPC1 - Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic | Phase 1 | Recruiting | Lineage Cell Therapeutics, Inc. | 10 | 2025-06-30 | 2026-02-12 |
| Gecacitinib for cGVHD: Safety and Efficacy in Patients After ≥2 Lines of Prior Therapy Gecacitinib Hydrochloride Tablets - Chronic Graft Versus Host Disease | Phase 1 / Phase 2 | Recruiting | Yujun DONG | 24 | 2025-06-30 | 2025-06-10 |
| A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD INCA034176 - Chronic Graft-versus-host-disease | Phase 1 / Phase 2 | Active not recruiting | Incyte Corporation | 32 | 2025-06-25 | 2026-08-10 |
| Upfront Ruxolitinib for Chronic Graft-vs-host Disease Ruxolitinib - Chronic Graft Versus Host Disease | Phase 1 | Terminated | Children's Hospital Medical Center, Cincinnati | 1 | 2025-02-19 | 2026-02-25 |
| Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders Tafasitamab, Fludarabine phosphate, Cyclophosphamide - Autoimmune Disorders, Systemic Sclerosis | Phase 1 / Phase 2 | Recruiting | M.D. Anderson Cancer Center | 47 | 2024-07-31 | 2026-10-06 |
| Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) TRX103 - Hematologic Malignancy, GvHD | Phase 1 | Recruiting | Tr1X, Inc. | 36 | 2024-04-08 | 2025-04-15 |
| A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection RSP-1502, Tobramycin inhalation solution - Cystic Fibrosis Lung, Respiratory Infections, Recurrent, Chronic | Phase 1 / Phase 2 | Completed | Respirion Pharmaceuticals Pty Ltd | 71 | 2024-04-01 | 2026-06-25 |
| Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation Biopsy, Biospecimen Collection, Chimeric Antigen Receptor T-Cell Therapy - Chronic Graft Versus Host Disease, Hematologic and Lymphocytic Disorder | Phase 1 | Suspended | City of Hope Medical Center | 27 | 2024-02-19 | 2025-11-13 |
| TDI01 Suspension in the Treatment of Chronic Graft-versus-host Disease (cGVHD)) TDI01 suspension - GVHD, Chronic | Phase 1 / Phase 2 | Active not recruiting | Beijing Tide Pharmaceutical Co., Ltd | 60 | 2024-02-06 | 2025-09-26 |
| Intracerebral Transplantation of Autologous MSC Combined With Scaffold Product for Chronic Intracerebral Hemorrhage HUFF-01 - Intracerebral Hemorrhage | Phase 1 / Phase 2 | Active not recruiting | Hokkaido University Hospital | 8 | 2023-12-01 | 2026-10-15 |
| Study to Assess the Safety of DERMASEAL for Diabetic Foot Ulcers DERMASEAL, Plasma Film, Standard of Care - Foot Ulcer, Diabetic | Phase 1 | Active not recruiting | Vitruvian Medical Devices, Inc. | 26 | 2022-10-03 | 2024-12-27 |
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Bronchiolitis Obliterans Syndrome (95) · Graft vs Host Disease (16) · Leukemia (9) · Bronchiolitis Obliterans (8) · Hematologic Neoplasms (6) · Leukemia, Lymphocytic, Chronic, B-Cell (6) · Neoplasms (6) · Lymphoma, Follicular (5) · Stroke (5) · Hepatitis B (4) · Hepatitis B, Chronic (4) · Hepatitis C (4) · Lymphoma (4) · Multiple Myeloma (4)
Bronchial Diseases (109) · Bronchitis (109) · Lung Diseases, Obstructive (109) · Respiratory Tract Diseases (109) · Lung Diseases (108) · Organizing Pneumonia (95) · Bronchiolitis Obliterans (93) · Immune System Diseases (93) · Graft vs Host Disease (79) · Pathological Conditions, Signs and Symptoms (31) · Pathologic Processes (25) · Hemic and Lymphatic Diseases (23) · Infections (20) · Disease Attributes (19)
Sirolimus (4) · ibrutinib (4) · Cyclophosphamide (3) · Interleukin-2 (3) · Mycophenolic Acid (3) · Rituximab (3) · ruxolitinib (3) · Busulfan (2) · INCB039110 (2) · KW-2478 (2) · Saline Solution (2) · Standard of Care (2) · Tacrolimus (2) · axatilimab (2) · belumosudil (2)
National Cancer Institute (NCI) (5) · Dana-Farber Cancer Institute (4) · Hoffmann-La Roche (4) · M.D. Anderson Cancer Center (4) · Children's Hospital Medical Center, Cincinnati (3) · Pharmacyclics LLC. (3) · Amgen (2) · AstraZeneca (2) · City of Hope Medical Center (2) · Genta Incorporated (2) · H. Lee Moffitt Cancer Center and Research Institute (2) · Incyte Corporation (2) · Kyowa Kirin Co., Ltd. (2) · Medical College of Wisconsin (2) · Alexion Pharmaceuticals, Inc. (1)
United States (65) · China (11) · United Kingdom (8) · Australia (6) · Canada (5) · Spain (5) · Israel (4) · France (3) · Italy (3) · Netherlands (3) · Japan (2) · New Zealand (2) · Poland (2) · Russia (2) · Austria (1)
Amandeep Salhotra (2) · Amin Alousi, MD (2) · Christopher G Kanakry, M.D. (2) · Pooja Khandelwal, MD (2) · Aldo T Iacono, MD (1) · Alexander Thompson, MD, PhD (1) · Amir Kugelman (1) · Anthony Rosner, PhD (1) · Arthur Tucker, PhD (1) · Asher Tal, M.D (1) · Attilio Olivieri, MD (1) · Carin Jorup, MD (1)
PMID 10048682, PMID 11815760, PMID 14757603, PMID 16186597, PMID 17015575, PMID 1731020, PMID 18214942, PMID 18595987, PMID 20100768, PMID 20113991, PMID 21817948, PMID 22129252, PMID 22487117, PMID 22734014, PMID 23861248, PMID 23903014, PMID 24586581, PMID 24995515, PMID 26059242, PMID 26945226, PMID 28072473, PMID 28924018, PMID 29549175, PMID 29843792, PMID 30333224, PMID 3069051, PMID 31260802, PMID 31471324, PMID 31668569, PMID 32508818, PMID 32981857, PMID 3339502, PMID 33883258, PMID 34102349, PMID 34398099, PMID 34649279, PMID 3513105, PMID 35475885, PMID 35641662, PMID 36189324, PMID 36459673, PMID 36862975, PMID 37698881, PMID 39704205, PMID 40009501, PMID 40554417, PMID 42200447, PMID 42495646, PMID 6129609, PMID 8238534
2009 (3), 2016 (1), 2017 (1), 2019 (1), P30CA033572 (1), R01CA183559 (1)