19 completed, 6 unknown, 3 recruiting, 2 terminated. 21 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 12, Unknown 3, Recruiting 2, Active not recruiting 1, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Breathlessness: new trials by email Literature Review of Breathlessness trials Research Report on Breathlessness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Management of Dyspnea With High- Flow Nasal Therapy High-flow nasal therapy, Airflow directed to face by a fan - Palliative Care, Breathlessness | Not applicable | Recruiting | Tampere University Hospital | 40 | 2026-06-01 | 2026-06-30 |
| Multicomponent Breathlessness and Physical Activity Intervention in People With Asthma Using a Digital Platform Multicomponent digital self-management platform, Enhanced usual care - Asthma (Diagnosis), Breathlessness | Not applicable | Not yet recruiting | University of Newcastle, Australia | 300 | 2026-03-01 | 2026-02-19 |
| Assessing the Effectiveness of Large Language Model (LLM)-Enabled Nurse Treatment Planning in 2 Indian Districts AI-enabled clinical decision support tool (software) used by nurses, Physician consultation - Hypertension, Diabete Mellitus | Not applicable | Completed | Sarah Nabia | 736 | 2026-01-13 | 2026-08-05 |
| Mindfulness-Oriented Respiratory Distress Symptom Intervention for Lung Cancer Mindfulness-Oriented Respiratory Distress Symptom Intervention (M-RDSI), Usual Care - Symptom Cluster, Breathlessness | Not applicable | Active not recruiting | The Hong Kong Polytechnic University | 70 | 2025-08-12 | 2026-09-17 |
| A Study to Evaluate the Effects of a Supplement on Mucus Clearance and Respiratory Symptoms BetterLungs, Placebo - Mucus Clearance, Respiratory Symptoms | Not applicable | Completed | The Better Brand Inc. | 100 | 2025-04-22 | 2026-08-03 |
| Reducing Breathlessness With Dronabinol in COPD Patients Dronabinol 2.5mg Capsule, Placebo - COPD, Breathlessness | Phase 3 | Completed | Vejle Hospital | 30 | 2025-02-26 | 2026-10-05 |
| The Physiotherapy Assessment of Breathing Pattern Disorder Assessment of Breathing Pattern- Breathing Pattern Assessment Tool - Breathing Pattern Disorder, Breathlessness | Recruiting | Royal Brompton & Harefield NHS Foundation Trust | 150 | 2024-12-10 | 2026-05-05 | |
| "Breathlessness Diagnostics in a Box" (BiaB) for Primary Care. A Multi-country Quality Improvement Project Using a Randomized Stepped-wedge Design Breathlessness diagnostics in a Box (BiaB) - Breathlessness, Cardiovascular | Not applicable | Recruiting | General Practitioners Research Institute | 900 | 2024-08-05 | 2026-01-07 |
| Connecting Breath and Mind for CYP With Long COVID Psychology interventions - Post-COVID-19 Syndrome, Anxiety | Not applicable | Unknown | Royal Brompton & Harefield NHS Foundation Trust | 40 | 2023-04-30 | 2023-09-08 |
| Effect of High Velocity/Hyperoxic Breathing Therapy on Blood Lactate Decline High Velocity Therapy - Dyspnea, Lactic Acidosis | Not applicable | Completed | Vapotherm, Inc. | 15 | 2023-03-06 | 2024-10-08 |
| Long COVID and Post-exertional Pulmonary Diffusion Lung volumes, spirometry and standard single-breath DLCO were measured at rest while combined DLNO and DLCO were measured at rest and post-exercise - Long COVID, Breathlessness | Completed | IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy | 32 | 2022-05-24 | 2022-06-24 | |
| Management of Breathlessness with High-flow Nasal Therapy or a Fan High-flow nasal therapy, Airflow directed to face by a fan - Breathlessness, Cancer | Not applicable | Completed | Tampere University Hospital | 36 | 2022-04-26 | 2025-01-31 |
| Sentinel - Triaging Acute Breathlessness Using Multi-Modal Biomarkers Biomarker tests for participant profiling - Breathlessness, COPD | Withdrawn | Sanome | 2022-03-01 | 2022-05-13 | ||
| Using a Fan With Aromatherapy in Breathlessness Patients in Terminal Illness Blow a fan to the face combine aromatherapy, Blow a fan to the face, Blow a fan to the feet - Breathlessness, Aromatherapy | Not applicable | Terminated | Tsai-Wei Huang | 26 | 2021-08-05 | 2026-06-26 |
| Dysfunctional Breathing: Characterisation and Assessment Short-form survey instrument, Demographic data, Hospital Anxiety and Depression Scale - Respiration Disorder, Hyperventilation Syndrome | Unknown | Brunel University | 141 | 2020-08-08 | 2020-07-08 | |
| Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness in Patients With Advanced Disease Cognitive and Behavioral intervention for the Management of Episodic Breathlessness - Dyspnea, Respiratory Insufficiency | Not applicable | Completed | University of Cologne | 49 | 2019-02-09 | 2020-11-16 |
| Biomarker for Cystic Fibrosis Chronic Nasal Congestion, Lung Infection | Terminated | CENTOGENE GmbH Rostock | 54 | 2018-08-20 | 2023-02-10 | |
| Melodica Orchestra for Dyspnea: Safety and Feasibility Pilot Melodica Intervention, Pulmonary Health Education - COPD, Chronic Obstructive Pulmonary Disease | Not applicable | Withdrawn | VA Quality Enhancement Research Intiative | 2018-06-12 | 2021-03-15 | |
| The Relating Experienced To Recalled Breathlessness Observational Study Breathlessness, Dyspnea | Completed | Skane University Hospital | 90 | 2018-05-11 | 2022-04-26 | |
| Breathlessness During Exercise: Experience and Memory Added exercise - Dyspnea, Breathlessness | Not applicable | Completed | Magnus Ekström | 92 | 2018-03-01 | 2019-09-18 |
Showing 20 of 34. Sign in to see all of them.
Dyspnea (34) · Pulmonary Disease, Chronic Obstructive (10) · Asthma (5) · Heart Failure (3) · Lung Neoplasms (3) · Neoplasms (3) · Anxiety Disorders (2) · Cough (2) · Fatigue (2) · Idiopathic Pulmonary Fibrosis (2) · Lung Diseases (2) · Lung Diseases, Interstitial (2) · Marijuana Abuse (2) · Motor Activity (2) · Post-Acute COVID-19 Syndrome (2)
Pathological Conditions, Signs and Symptoms (34) · Respiratory Tract Diseases (34) · Signs and Symptoms (34) · Respiration Disorders (33) · Signs and Symptoms, Respiratory (33) · Lung Diseases (20) · Pathologic Processes (14) · Chronic Disease (12) · Disease Attributes (12) · Lung Diseases, Obstructive (12) · Bronchial Diseases (6) · Infections (6) · Respiratory Tract Infections (6) · Hypersensitivity (5) · Hypersensitivity, Immediate (5)
4-amino-4'-hydroxylaminodiphenylsulfone (1) · Aging (1) · Behavior Therapy (1) · Body Height (1) · Breathing Exercises (1) · Calorimetry, Indirect (1) · Cognitive Behavioral Therapy (1) · Demography (1) · Dronabinol (1) · Exercise Test (1) · Furosemide (1) · Lung Volume Measurements (1) · Music Therapy (1) · Patient Health Questionnaire (1) · Respiratory Function Tests (1)
McGill University (2) · Royal Brompton & Harefield NHS Foundation Trust (2) · Tampere University Hospital (2) · Alisa Apreleva (1) · Brunel University (1) · CENTOGENE GmbH Rostock (1) · City, University of London (1) · General Practitioners Research Institute (1) · IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy (1) · Kirsehir Ahi Evran Universitesi (1) · Ludwig-Maximilians - University of Munich (1) · Magnus Ekström (1) · Massachusetts General Hospital (1) · Oslo University Hospital (1) · Portsmouth Hospitals NHS Trust (1)
United Kingdom (10) · United States (4) · Canada (3) · Finland (2) · Germany (2) · India (2) · Sweden (2) · Albania (1) · Australia (1) · Denmark (1) · Georgia (1) · Hong Kong (1) · Italy (1) · Netherlands (1) · Norway (1)
Dennis Jensen, Ph.D. (2) · Juho Lehto, Professor (2) · Alisa Apreleva, MA (1) · Anoop J Chauhan, PhD (1) · Bruce Gladden (1) · Claudia Bausewein, Prof.Dr.med. (1) · Dawn M Bravata, MD (1) · Doris Howell, RN PhD (1) · Ian Forrest, MRCP UK, PhD (1) · Jacob Sandberg, MD (1) · Joseph Greer, Ph.D. (1) · Lizzie JF Grillo, BSc MSc (1) · Martin Dr Cartwright, BSc, MSc, PhD (1) · Max Michael (1)
PMID 30049223, PMID 30852546, PMID 30956800, PMID 32915891, PMID 33064621, PMID 33509957, PMID 34760995, PMID 36028881, PMID 36369507, PMID 37268935, PMID 38191248, PMID 40914402, PMID 41698715, PMID 42205504