6 recruiting, 2 completed, 1 not yet recruiting. 3 Not applicable, 2 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Recruiting 2, Not yet recruiting 1 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Bipolar Disorder I or II: new trials by email Literature Review of Bipolar Disorder I or II trials Research Report on Bipolar Disorder I or II
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT) Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT) - Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder | Phase 2 | Recruiting | Joshua Rosenblat | 120 | 2026-07-16 | 2026-07-29 |
| FOCUS Bipolar: Families Opening Conversations for Understanding Signs Co-design Workshop (Observational Procedure), Alpha Testing (Observational Procedure), Beta Testing (Observational Procedure) - Bipolar Disorder (BD), Bipolar Disorder I or II | Recruiting | University of Texas Southwestern Medical Center | 200 | 2026-03-11 | 2026-06-03 | |
| Decoding Emotional Dynamics in Bipolar Disorder Think and Regulate Affective State Task - Bipolar Disorder I or II, Healthy (Controls) | Not applicable | Recruiting | Laureate Institute for Brain Research, Inc. | 72 | 2025-10-30 | 2026-04-17 |
| A Compassionate-focused Intervention for Older People with Bipolar Disorder Compassionate-focused therapy - Bipolar Disorder I or II | Not applicable | Not yet recruiting | University of Manchester | 6 | 2025-07-01 | 2025-03-18 |
| Exercise and Olanzapine-samidorphan Olanzapine-samidorphan + exercise - Schizophenia Disorder, Schizoaffective Disorder | Phase 4 | Recruiting | New York State Psychiatric Institute | 30 | 2025-06-26 | 2026-07-13 |
| Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents Ketogenic Therapy - Bipolar Disorder (BD), Bipolar Disorder NOS | Not applicable | Recruiting | University of California, Los Angeles | 80 | 2025-03-19 | 2026-04-22 |
| The Bipolar Lithium Imaging Scan Study. Lithium MR imaging - Bipolar Disorder I or II | Recruiting | Leiden University Medical Center | 80 | 2024-03-13 | 2024-12-13 | |
| Tranylcypromine Treatment of Bipolar Depression Tranylcypromine - Bipolar Disorder I or II | Phase 4 | Completed | New York State Psychiatric Institute | 7 | 2011-11-01 | 2018-03-15 |
| Validation of Multidimensional Assessment of THYmic States (MATHYS): A Study in a Population of Bipolar Patients Treated With Olanzapine olanzapine - Bipolar Disorder I or II | Phase 3 | Completed | Eli Lilly and Company | 141 | 2005-11-01 | 2009-06-24 |
Bipolar Disorder (8) · Depressive Disorder, Major (2) · Borderline Personality Disorder (1) · Depression (1) · Depressive Disorder, Treatment-Resistant (1) · Emotional Regulation (1) · Motor Activity (1) · Psychotic Disorders (1) · Rumination Syndrome (1) · Suicidal Ideation (1)
Bipolar and Related Disorders (8) · Mental Disorders (8) · Mood Disorders (8) · Behavior (4) · Behavioral Symptoms (2) · Depressive Disorder (2) · Digestive System Diseases (1) · Feeding and Eating Disorders (1) · Gastrointestinal Diseases (1) · Personality Disorders (1) · Schizophrenia Spectrum and Other Psychotic Disorders (1) · Self-Control (1) · Self-Injurious Behavior (1) · Social Behavior (1) · Suicide (1)
Exercise (1) · Ketamine (1) · Midazolam (1) · Olanzapine (1) · Tranylcypromine (1)
New York State Psychiatric Institute (2) · Eli Lilly and Company (1) · Joshua Rosenblat (1) · Laureate Institute for Brain Research, Inc. (1) · Leiden University Medical Center (1) · University of California, Los Angeles (1) · University of Manchester (1) · University of Texas Southwestern Medical Center (1)
United States (5) · Canada (1) · France (1) · Netherlands (1) · United Kingdom (1)
E Boere, MD (1) · Joshua D. Rosenblat, MD, MSc (1) · Karabi Nandy, PhD (1)
P20GM121312 (1)