17 completed, 3 terminated, 3 unknown, 2 recruiting. 9 Phase 2, 7 Phase 3, 7 Phase 4, 4 Not applicable, 3 Phase 1.
Follow SLI381: new trials by email Literature Review of SLI381 trials Research Report on SLI381
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine Adderall XR (mixed salts amphetamine), Placebo - Attention Deficit Hyperactivity Disorder (ADHD), Autism | Phase 4 | Recruiting | Gagan Joshi | 196 | 2026-02-01 | 2026-03-06 |
| Addressing Cognitive Fog in Long-COVID-19 Patients Digital cognitive behavioral intervention-RxWell, Amphetamine-Dextroamphetamine - Cognitive Impairment, Long COVID | Phase 4 | Terminated | Eva Szigethy | 7 | 2023-04-04 | 2024-07-22 |
| Biomarkers of ADHD Treatment Response Concerta, Adderall-XR - ADHD | Phase 1 | Completed | Boston Children's Hospital | 16 | 2023-02-17 | 2024-12-18 |
| Psychostimulant Augmentation of Repetitive TMS for the Treatment of Major Depressive Disorder Adderall-XR, Placebo - Major Depressive Disorder | Early Phase 1 | Enrolling by invitation | University of California, Los Angeles | 30 | 2021-09-27 | 2026-02-03 |
| Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care: - Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension | Recruiting | Duke University | 5000 | 2020-03-05 | 2026-08-21 | |
| Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder Adderall - Attention Deficit Disorder With Hyperactivity, Conduct Disorder | Phase 4 | Completed | Jeffrey Newcorn | 33 | 2019-11-05 | 2024-08-29 |
| Modafinil Versus Amphetamines for the Treatment of Narcolepsy Type 2 and Idiopathic Hypersomnia Modafinil, Amphetamine-Dextroamphetamine - Idiopathic Hypersomnia, Narcolepsy Without Cataplexy | Phase 2 | Completed | Emory University | 44 | 2019-04-15 | 2024-05-23 |
| Treatment of Cannabis Use Disorder Among Adults With Comorbid Attention-Deficit/Hyperactivity Disorder Adderall-XR, Matched placebo - Cannabis Use Disorder, Attention-deficit/Hyperactivity Disorder | Phase 2 / Phase 3 | Completed | New York State Psychiatric Institute | 33 | 2016-07-01 | 2021-04-09 |
| Adderall XR and Cognitive Impairment in MS Adderall XR - Multiple Sclerosis | Phase 2 / Phase 3 | Active not recruiting | Sarah Morrow | 180 | 2016-05-20 | 2024-10-17 |
| The Effectiveness of Aerobic Exercise in the Treatment of Adults With Attention Deficit Hyperactivity Disorder (ADHD) Methylphenidate compounds and /or Amphetamine compounds and/or Strattera or Guanfacine, Aerobic Exercise - Attention Deficit Hyperactivity Disorder (ADHD) | Not applicable | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 70 | 2016-04-01 | 2018-08-15 |
| A Sequenced Behavioral and Medication Intervention for Cocaine Dependence Computer-assisted behavior therapy, Mixed-Amphetamine Salts- Extended Release (MAS-ER), Placebo - Cocaine Dependence | Phase 1 / Phase 2 | Completed | New York State Psychiatric Institute | 145 | 2014-01-01 | 2022-01-25 |
| Adderall XR and Processing Speed in Multiple Sclerosis (MS) Adderall XR 5mg, Adderall XR 10 mg, Placebo - Impaired Processing Speed, Cognitive Impairment | Phase 2 / Phase 3 | Completed | London Health Sciences Centre | 70 | 2012-09-01 | 2015-05-12 |
| Stimulant Enhancement of Well-Being Therapy for Depression Amphetamine/dextroamphetamine, Placebo, Well-being therapy - Major Depressive Disorder | Not applicable | Terminated | Massachusetts General Hospital | 5 | 2012-02-01 | 2017-04-26 |
| Cognitive Behavioral Therapy for Adolescents With Attention-Deficit / Hyperactivity Disorder Cognitive Behavioural & Skills Training, Supportive Group Therapy, Treatment as Usual - community resources - Attention Deficit Hyperactivity Disorder | Phase 4 | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 216 | 2010-10-01 | 2018-07-31 |
| Comparing the Effectiveness of New Versus Older Treatments for Attention Deficit Hyperactivity Disorder (The NOTA Study) Methylphenidate transdermal system, Lisdexamfetamine dimesylate, Osmotic-release oral system methylphenidate (OROS MPH) - Attention Deficit Disorder With Hyperactivity | Phase 4 | Completed | Duke University | 228 | 2009-04-01 | 2013-09-30 |
| Vyvanse and Adderall XR Given Alone and in Combination With Prilosec OTC Lisdexamfetamine Dimesylate, Adderall XR (mixed salts amphetamine) - Healthy Volunteers | Phase 1 | Completed | Shire | 24 | 2008-09-08 | 2021-06-14 |
| Effectiveness of an Extended Release Stimulant Medication in Treating Preschool Children With ADHD Sequence 1: XR-MAS then placebo, Sequence 2 Placebo then XR-MAS - Attention Deficit Disorder With Hyperactivity | Not applicable | Completed | Baystate Medical Center | 27 | 2008-06-01 | 2013-08-23 |
| Study of Adderall-XR for the Treatment of Adult Attention Deficit Hyperactivity Disorder and Cocaine Dependence Placebo, Adderall-XR - Adult Attention Deficit Hyperactivity Disorder, Cocaine Dependence | Phase 2 / Phase 3 | Completed | New York State Psychiatric Institute | 139 | 2007-12-01 | 2019-04-24 |
| A Within-Subject Cross-Over Comparison Between Immediate Release and Extended Release Adderall Adderall ® Immediate Release, Adderall XR ® - Attention Deficit Hyperactivity Disorder | Phase 4 | Completed | NYU Langone Health | 62 | 2007-08-01 | 2016-06-02 |
| A Placebo-Controlled Study of Mixed Amphetamine Salts and Topiramate for the Treatment of Cocaine Dependence Adderall-XR and Topiramate, Placebo - Cocaine Dependence | Phase 2 | Completed | New York State Psychiatric Institute | 81 | 2007-02-01 | 2019-04-24 |
Showing 20 of 27. Sign in to see all of them.
Attention Deficit Disorder with Hyperactivity (18) · Cocaine-Related Disorders (3) · Cognitive Dysfunction (2) · Depression (2) · Depressive Disorder, Major (2) · Multiple Sclerosis (2) · Adrenal Insufficiency (1) · Arrhythmias, Cardiac (1) · Autism Spectrum Disorder (1) · Autistic Disorder (1) · Bronchopulmonary Dysplasia (1) · COVID-19 (1) · Cellulitis (1) · Conduct Disorder (1) · Coronavirus Infections (1)
New York State Psychiatric Institute (4) · Shire (4) · Duke University (2) · McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · Baystate Medical Center (1) · Boston Children's Hospital (1) · Emory University (1) · Eva Szigethy (1) · Gagan Joshi (1) · Jeffrey Newcorn (1) · Lily Hechtman (1) · London Health Sciences Centre (1) · Massachusetts General Hospital (1) · NYU Langone Health (1) · New River Pharmaceuticals (1)
United States (20) · Canada (6)
Lily Hechtman, MD, FRCPC (3) · Frances R Levin, M.D. (2) · Frances R Levin, MD (2) · Ann Childress, M.D. (1) · Anne B Arnett, PhD (1) · Chi Hornik (1) · Elizabeth Charney, MD (1) · Eugenia Chan, MD (1) · Eva Szigethy, MD, PhD (1) · Frank Lopez, M.D. (1) · Gagan Joshi, MD (1) · Iliyan Ivanov, MD (1) · Jeffrey Newcorn, MD (1) · John Grabowski (1)
PMID 16371674, PMID 16678648, PMID 17631866, PMID 18815438, PMID 19820270, PMID 20215923, PMID 21474905, PMID 21904088, PMID 22136094, PMID 25056567, PMID 25887096, PMID 33086160, PMID 37732961, PMID 39306601
F32MH078388 (1), P30MH066386 (1), R01DA022217 (1), R01DA023652 (1), R01DA034087 (1), R21DA046029 (1), U10CA081920 (1), U54DA037842 (1)