14 completed, 3 terminated, 1 unknown. 9 Phase 1, 2 Not applicable, 2 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 6, Terminated 3 |
| Not applicable | 2 | Completed 1, Unknown 1 |
| Phase 4 | 2 | Completed 2 |
| Phase 2 | 1 | Terminated 1 |
| Phase 3 | 1 | Completed 1 |
Follow Anti-Infective Agents: new trials by email Literature Review of Anti-Infective Agents trials Research Report on Anti-Infective Agents
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections - Canada Nasal antimicrobial photodisinfection therapy - Surgical Site Infections, Infections | Not applicable | Completed | Ondine Biomedical Inc. | 401 | 2026-01-13 | 2026-09-15 |
| Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections nasal antimicrobial photodisinfection therapy - Surgical Site Infections, Surgical Wound Infection | Phase 3 | Completed | Ondine Biomedical Inc. | 4787 | 2024-12-27 | 2026-09-15 |
| Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum MMV367 3mg, P. falciparum IBSM infection, MMV367 5mg - Infections, Vector Borne Diseases | Phase 1 | Completed | Medicines for Malaria Venture | 12 | 2023-08-01 | 2025-12-10 |
| Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral Products Vaccines, Antiviral Agents | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 9 | 2023-04-24 | 2025-05-16 | |
| Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM CYNK001-IV, CYNK001-IT - Astrocytoma, Grade IV, Giant Cell Glioblastoma | Phase 1 | Terminated | Celularity Incorporated | 3 | 2020-10-01 | 2022-08-10 |
| Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19 CYNK-001 - Coronavirus, Coronavirus Infection | Phase 1 / Phase 2 | Terminated | Celularity Incorporated | 7 | 2020-09-02 | 2026-06-26 |
| A Digital Antimicrobial Stewardship Smartphone Application to Combat AMR: the AB-assistant AB-assistant - Anti-Infective Agents, Mobile Applications | Not applicable | Unknown | Annelies Verbon | 1080 | 2020-09-01 | 2020-08-04 |
| Natural Killer Cell (CYNK-001) Infusions in Adults with AML CYNK-001 - Leukemia, Leukemia, Myeloid | Phase 1 | Terminated | Celularity Incorporated | 27 | 2020-03-12 | 2024-12-12 |
| Neuroimmune Dysfunction in Alcohol Use Disorder Minocycline, Sugar pill - Alcohol Drinking, Alcohol-Related Disorders | Phase 1 | Completed | University of Maryland, Baltimore | 142 | 2020-02-03 | 2023-12-01 |
| Compliance of Initial Empiric Antimicrobial Therapy microbiological investigation - Anti-Infective Agents | Completed | Military Institute od Medicine National Research Institute | 267 | 2018-02-01 | 2020-06-29 | |
| Safety, PK, and PD Study of IVRs Releasing TFV and LNG TFV/LNG IVR, Placebo - Anti-Infective Agents, Anti-Retroviral Agents | Phase 1 | Completed | CONRAD | 66 | 2017-09-28 | 2019-07-23 |
| Probiotics to Promote Intestinal Health Probiotic, Placebo - Communicable Diseases, Infection | Phase 4 | Completed | Washington University School of Medicine | 89 | 2014-01-01 | 2022-04-04 |
| Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction Cefadroxil discontinued early, Cefadroxil until drain removal - Bacterial Infection, Anti-infective Agents | Phase 4 | Completed | Stony Brook University | 132 | 2010-11-01 | 2014-05-13 |
| Acceptability Study of Vaginal Films for HIV Prevention No intervention (not applicable) - HIV Infections, Anti-Infective Agents | Completed | University of Pittsburgh | 84 | 2010-11-01 | 2011-02-09 | |
| Cross Over Study to Prove Bioequivalence Between Two Brands of Cefalexin Suspension Cephalexin suspension (Optocef, BAYO5448 ), Cephalexin suspension (Keflex) - Anti-Infective Agents | Phase 1 | Completed | Bayer | 26 | 2010-03-01 | 2014-05-20 |
| Cross-over Study to Prove Bioequivalence Between Two Brands of Cefalexin Capsules Cephalexin capsules (Optocef, BAYO5448 ), Cephalexin capsules (Keflex) - Anti-Infective Agents | Phase 1 | Completed | Bayer | 26 | 2009-10-01 | 2015-04-03 |
| Cross-over Study to Prove Bioequivalence Between Two Brands of Cefalexin Suspension Cephalexin suspension (Optocef, BAYO5448), Cephalexin suspension (Keflex) - Anti-Infective Agents | Phase 1 | Completed | Bayer | 26 | 2009-09-01 | 2014-04-03 |
| Special Drug Use Investigation - Assessment of Efficacy and Safety in Treating Secondary Infection of Chronic Respiratory Disease Avelox (Moxifloxacin, BAY12-8039) - Anti-Infective Agents | Completed | Bayer | 497 | 2008-05-13 | 2018-05-21 |
Infections (4) · Surgical Wound Infection (3) · Inflammation (2) · Pathologic Processes (2) · Pneumonia (2) · Staphylococcal Infections (2) · Alcohol Drinking (1) · Alcohol-Related Disorders (1) · Alcoholism (1) · Bacterial Infections (1) · Bronchitis (1) · COVID-19 (1) · Chemically-Induced Disorders (1) · Cognition Disorders (1) · Cognitive Dysfunction (1)
Pathological Conditions, Signs and Symptoms (8) · Pathologic Processes (6) · Infections (5) · Bacterial Infections and Mycoses (3) · Postoperative Complications (3) · Wound Infection (3) · Bacterial Infections (2) · Behavior (2) · Disease Attributes (2) · Gram-Positive Bacterial Infections (2) · Astrocytoma (1) · Blood-Borne Infections (1) · Bronchial Diseases (1) · Communicable Diseases (1) · Genital Diseases (1)
Cephalexin (3) · Cefadroxil (1) · Cefazolin (1) · Clindamycin (1) · Minocycline (1) · Moxifloxacin (1) · Probiotics (1) · Sugars (1) · Tenofovir (1)
Bayer (4) · Celularity Incorporated (3) · Ondine Biomedical Inc. (2) · Annelies Verbon (1) · CONRAD (1) · Medicines for Malaria Venture (1) · Military Institute od Medicine National Research Institute (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Stony Brook University (1) · University of Maryland, Baltimore (1) · University of Pittsburgh (1) · Washington University School of Medicine (1)
United States (10) · Mexico (3) · Canada (2) · Australia (1) · Dominican Republic (1) · Japan (1) · Netherlands (1) · Poland (1) · Sweden (1) · Switzerland (1)
B D Huttner, MD, MS (1) · Benoit Bestgen, PhD (1) · Brett T Phillips, MD (1) · Corey Casper, MD MPH (1) · Dariusz Tomaszewski, MD, PhD (1) · Duc T Bui, MD (1) · John Conly, Prof. Dr. (1) · Richard T Davey, M.D. (1) · Sharmila Koppisetti, M.D (1) · Sharmila Koppisetti, MD (1) · Sharon Hillier, PhD (1) · Simon Sinclair, MD, PhD (1)
PMID 27106640, PMID 32503867, PMID 35350436, PMID 35363574, PMID 36215267, PMID 40032084, PMID 40483726
K01AA026005 (1)