221 completed, 69 unknown, 21 recruiting, 16 terminated. 67 Not applicable, 50 Phase 3, 45 Phase 2, 39 Phase 4, 13 Phase 1.
Follow Ankylosing Spondylitis: new trials by email Literature Review of Ankylosing Spondylitis trials Research Report on Ankylosing Spondylitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients Meibomian Gland Dysfunction, Dry Eye Syndromes | Not yet recruiting | Assiut University | 150 | 2026-10-01 | 2026-09-09 | |
| Evaluation of Serum IL-41 Level in Patients With Ankylosing Spondylitis and Psoriatic Arthritis IL 41 - Ankylosing Spondylitis, Psoriasis | Not yet recruiting | Assiut University | 90 | 2026-10-01 | 2026-07-21 | |
| A Study to Assess the Safety of Subcutaneous Secukinumab for Treatment in Adult Indian Participants With Axial Spondyloarthritis (axSpA), Ankylosing Spondylitis (AS), and Non-Radiographic Axial Spondyloarthritis (nr-axSpA) Axial Spondyloarthritis, Ankylosing Spondylitis | Not yet recruiting | Novartis Pharmaceuticals | 60 | 2026-09-30 | 2026-07-30 | |
| Surface Topography and Radiographic Spinal Damage in Radiographic Axial Spondyloarthritis DIERS Formetric 4D surface topography - Axial Spondyloarthritis, Ankylosing Spondylitis | Recruiting | Ankara Etlik City Hospital | 53 | 2026-09-19 | 2026-10-02 | |
| Vilamakitug in Spondyloarthritis Placebo-controlled Investigation for Efficacy vilamakitug, placebo - Axial Spondyloarthritis, Ankylosing Spondylitis | Phase 2 | Not yet recruiting | XBiotech, Inc. | 150 | 2026-09-01 | 2026-05-14 |
| 15-Hydroxyprostaglandin Dehydrogenase in Osteoarthritis and Ankylosing Spondylitis Osteoarthritis, Ankylosing Spondylitis | Not yet recruiting | Assiut University | 51 | 2026-08-02 | 2026-08-07 | |
| Safety and Efficacy of Allogeneic Bone Marrow MSCs in Ankylosing Spondylitis IV administration of CG-BM1, Placebo, CG-BM1 - Ankylosing Spondylitis | Phase 1 | Not yet recruiting | Eighth Affiliated Hospital, Sun Yat-sen University | 40 | 2026-07-01 | 2026-06-08 |
| Assessment of Peripheral Neuropathy in Ankylosing Spondylitis Nerve conduction study - Ankylosing Spondylitis, Peripheral Neuropathies | Not yet recruiting | Assiut University | 45 | 2026-06-30 | 2026-06-12 | |
| Expression of Tim-3 on Neutrophils in Ankylosing Spondylitis Ankylosing Spondylitis, AS | Not yet recruiting | Assiut University | 81 | 2026-06-01 | 2026-02-03 | |
| A Phase I/Ⅱ Clinical Trial for Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in the Treatment of Ankylosing Spondylitis HS_SW01 cells injection - Ankylosing Spondylitis | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Huishan Biotechnology Co., Ltd. | 18 | 2026-04-10 | 2026-04-20 |
| Ankylosing Spondylitis Ankylosing Spondylitis | Not yet recruiting | Sohag University | 84 | 2026-03-01 | 2026-02-09 | |
| Skin Autofluorescence Assessment of Advanced Glycation End Products in Rheumatic Diseases Rheumatoid Arthritis (RA, Ankylosing Spondylitis | Not yet recruiting | Bursa City Hospital | 300 | 2026-01-15 | 2026-01-09 | |
| A Randomized Trial of Ultrasound-Guided Acupotomy for Ankylosing Spondylitis Ultrasound-guided acupotomy, Sham Acupotomy - Ankylosing Spondylitis | Not applicable | Recruiting | China-Japan Friendship Hospital | 60 | 2025-12-02 | 2026-10-15 |
| Impact of Low Back Pain Phenotypes on Function and Quality of Life in Ankylosing Spondylitis Ankylosing Spondylitis, Low Back Pain | Recruiting | Konya Beyhekim Training and Research Hospital | 200 | 2025-12-01 | 2026-04-03 | |
| A Study to Evaluate the Efficacy and Safety of 608 in Adult Subjects With Active Ankylosing Spondylitis(AS) 608 dose, Placebo - Ankylosing Spondylitis | Phase 3 | Recruiting | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 500 | 2025-11-07 | 2025-12-10 |
| Activating the Cholinergic Anti-Inflammatory Pathway in Healthy Volunteers and People With Inflammatory Arthritis Ultrasound Stimulation, Non-active ultrasound stimulation - Psoriatic Arthritis, Rheumatoid Arthritis | Not applicable | Completed | Surf Therapeutics | 16 | 2025-10-01 | 2026-01-07 |
| A Study to Evaluate Efficacy and Safety of LNK01001 in Adults With Ankylosing Spondylitis LNK01001, Placebo - Ankylosing Spondylitis | Phase 3 | Recruiting | Lynk Pharmaceuticals Co., Ltd | 352 | 2025-08-29 | 2025-11-20 |
| Effects of Progressive Relaxation Exercises Applied to Patients With Ankylosing Spondylitis on Pain and Fatigue Levels Progressive Relaxation Exercises - Ankylosing Spondylitis | Not applicable | Not yet recruiting | University of Gaziantep | 50 | 2025-07-15 | 2025-07-10 |
| Mass Spectrometry-based Immune Profiling in Autoimmune Diseases Systemic Lupus Erthematosus, Sjogren's Syndrome | Enrolling by invitation | Peking University People's Hospital | 500 | 2025-05-25 | 2026-08-26 | |
| Real-world Study on Secukinumab Effectiveness in Biologic-naïve Ankylosing Spondylitis (AS) Patients in Korea. Secukinumab - Ankylosing Spondylitis | Recruiting | Novartis Pharmaceuticals | 70 | 2025-04-02 | 2026-08-18 |
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Spondylitis, Ankylosing (359) · Arthritis, Rheumatoid (94) · Arthritis, Psoriatic (71) · Axial Spondyloarthritis (27) · Crohn Disease (27) · Arthritis (23) · Spondylarthritis (23) · Psoriasis (21) · Colitis, Ulcerative (19) · Lupus Erythematosus, Systemic (17) · Osteoarthritis (15) · Spondylarthropathies (14) · Spondylitis (11) · Autoimmune Diseases (10) · Motor Activity (10)
Ankylosis (359) · Bone Diseases (359) · Joint Diseases (358) · Musculoskeletal Diseases (358) · Spinal Diseases (357) · Spondylitis (348) · Spondylarthropathies (345) · Arthritis (336) · Spondylarthritis (336) · Axial Spondyloarthritis (332) · Skin and Connective Tissue Diseases (110) · Connective Tissue Diseases (101) · Immune System Diseases (99) · Rheumatic Diseases (96) · Autoimmune Diseases (89)
Etanercept (35) · Adalimumab (23) · Infliximab (20) · secukinumab (13) · golimumab (10) · Celecoxib (7) · Certolizumab Pegol (5) · Exercise (5) · Methotrexate (5) · Sulfasalazine (5) · bimekizumab (5) · Anti-Inflammatory Agents, Non-Steroidal (4) · Control Groups (4) · Etoricoxib (4) · GLPG0634 (4)
Pfizer (15) · Wyeth is now a wholly owned subsidiary of Pfizer (14) · Novartis Pharmaceuticals (11) · Charite University, Berlin, Germany (10) · AbbVie (prior sponsor, Abbott) (8) · Abbott (7) · AbbVie (6) · Assiut University (6) · Istanbul Physical Medicine Rehabilitation Training and Research Hospital (6) · Sun Yat-sen University (6) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (5) · Assistance Publique - Hôpitaux de Paris (4) · Bezmialem Vakif University (4) · Biocad (4) · Celltrion (4)
Turkey (Türkiye) (59) · United States (54) · China (48) · France (38) · Germany (36) · United Kingdom (23) · Netherlands (21) · South Korea (20) · Spain (20) · Canada (18) · Belgium (17) · Czechia (17) · Poland (17) · Russia (15) · Sweden (12)
Joachim Sieper, MD (4) · Chunde Bao (3) · Jieruo Gu, Prof (3) · Joachim Sieper, Prof. (3) · Robert A Colbert, M.D. (3) · Roman Ivanov, PhD (3) · Astrid Dworan-Timler, MD (2)
PMID 38488976, PMID 30473179, PMID 40194794, PMID 41807031, PMID 15051621, PMID 19703304, PMID 21600054, PMID 35833532, PMID 36058784, PMID 36138330, PMID 37909386, PMID 38696034, PMID 38825359, PMID 38977276, PMID 39636343, PMID 39695887, PMID 39890205, PMID 41125403, PMID 41314667, PMID 42128532, PMID 42297437, PMID 42386286, PMID 11427222, PMID 14581396, PMID 14613285, PMID 15365877, PMID 15517638, PMID 15692973, PMID 15843448, PMID 16342093, PMID 16646033, PMID 16874778, PMID 17728332, PMID 17906496, PMID 17967833, PMID 18050198, PMID 18056755, PMID 18163509, PMID 18278836, PMID 18383418, PMID 18438853, PMID 18576337, PMID 18662932, PMID 18701556, PMID 18759257, PMID 19060001, PMID 19140539, PMID 19208593, PMID 19273449, PMID 19411393
2017 (5), 2008 (4), 2009 (4), 2015 (3), 2019 (3), 2018 (2), 2023 (2), 2014 (1), 2016 (1), K08CA237619 (1), P60AR020613 (1), R01AR046208 (1)