21 completed, 8 unknown, 4 recruiting, 3 not yet recruiting. 12 Not applicable, 3 Phase 2, 3 Phase 4, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 9, Unknown 2, Recruiting 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 4 | 3 | Completed 1, Not yet recruiting 1, Terminated 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow AKI: new trials by email Literature Review of AKI trials Research Report on AKI
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| mGFR vs tGFR in AKI transdermal GFR - AKI, GFR | Phase 4 | Not yet recruiting | Bin Du | 50 | 2026-06-08 | 2026-06-10 |
| What Are the Predictors of Acute Kidney Injury in Children Admitted to Pediatrics Intensive Care Unit at Assiut University Children Hospital? Clinical and laboratory assessment - AKI, ICU | Not yet recruiting | Assiut University | 100 | 2026-05-01 | 2026-04-08 | |
| What is the Effect of Acute Kidney Injury on Weaning From Mechanical Ventilation in Critically Ill Adult Patients? Acute Kidney Injury (AKI) Exposure - AKI, Critical Illness | Not yet recruiting | Assiut University | 85 | 2026-04-01 | 2026-03-17 | |
| Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America Dialysis, Critically Ill Acute Kidney Injury | Recruiting | University of Alabama at Birmingham | 1000 | 2026-03-01 | 2026-03-12 | |
| Outpatient Recovery From Acute Kidney Injury Requiring Dialysis - 2 Transmission of additional AKI-D recovery information, No additional AKI-D recovery information - AKI, AKI - Acute Kidney Injury | Not applicable | Recruiting | University of California, San Francisco | 40 | 2026-02-23 | 2026-02-27 |
| Hyperoxia vs Normoxia During Cardiopulmonary Bypass Hyperoxia group, Normoxia group (control) - AKI, Renal Replacement Therapy | Not applicable | Completed | University of Padova | 104 | 2025-07-01 | 2026-04-03 |
| Deep Learning Model and Risk Factors for Tacrolimus-related Acute Kidney Injury AKI | Active not recruiting | Qianfoshan Hospital | 1200 | 2024-09-01 | 2024-09-19 | |
| Research on the Risk Warning Model and Prevention Strategies for Acute Kidney Injury Associated With Cyclosporine Based on Explainable Deep Neural Networks and Therapeutic Drug Monitoring AKI, Therapeutic Drug Monitoring (TDM) | Active not recruiting | Qianfoshan Hospital | 1200 | 2024-09-01 | 2024-09-19 | |
| NO During CPB in Neonates to Reduce Risk of AKI Nitric Oxide, Oxygen - AKI, CHD - Congenital Heart Disease | Phase 3 | Recruiting | Children's Hospital Medical Center, Cincinnati | 40 | 2023-01-10 | 2026-08-05 |
| Nafamostat Mesilate for Anticoagulation During CRRT in Critically Ill Patients Sepsis Syndrome, MODS | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 188 | 2022-05-31 | 2022-05-19 | |
| Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Hepatorenal Syndrome-Acute Kidney Injury Echocardiographic assessment - Hepatorenal Syndrome, Cirrhosis, Liver | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 75 | 2021-12-15 | 2023-05-01 | |
| Effect of Antibiotic Choice On ReNal Outcomes (ACORN) anti-pseudomonal cephalosporin, anti-pseudomonal penicillin - Sepsis, AKI | Phase 4 | Completed | Vanderbilt University Medical Center | 2634 | 2021-11-10 | 2023-12-22 |
| Effect of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing CABG and/or Cardiac Valve Surgery Low Dose RBT-1, High Dose RBT-1, Placebo - AKI | Phase 2 | Completed | Renibus Therapeutics, Inc. | 152 | 2021-08-04 | 2024-04-15 |
| El DORADO STUDY (Evaluation of Delivery of Oxygen on Renal, Arrhythmia and Delirium Outcomes Study) Edwards ClearSight and Masimo SET - AKI, Neurocognitive Disorders | Unknown | National University Hospital, Singapore | 600 | 2021-07-27 | 2023-07-27 | |
| Separation Versus Integrated Approach in Combining ECMO With CRRT Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy - AKI | Not applicable | Completed | Chulalongkorn University | 80 | 2021-04-01 | 2025-12-19 |
| Renal Involvement in Hospitalized Children With COVID-19 data review, data comparing - Acute Kidney Injury, Covid19 | Completed | Hamad Medical Corporation | 400 | 2021-03-01 | 2023-07-25 | |
| Protection From Acute Kidney Injury (AKI) With Basis™ Treatment Nicotinamide Riboside + Pterostilbene, Placebo - AKI | Phase 2 | Completed | Mayo Clinic | 54 | 2020-12-01 | 2024-04-23 |
| Renal Physiology During Continuous Renal Replacement Therapy Starting at high or low blood pressure - AKI, Continuous Renal Replacement Therapy | Not applicable | Unknown | Sahlgrenska University Hospital | 20 | 2020-11-20 | 2024-04-18 |
| Coronavirus Induced Acute Kidney Injury: Prevention Using Urine Alkalinization Sodium bicarbonate, Standard of Care - COVID, Coronavirus | Phase 4 | Terminated | West Virginia University | 3 | 2020-10-05 | 2023-12-22 |
| Efficacy and Safety of a Highly Selective Semipermeable Membrane (AN-69 Oxiris) vs (Standard AN-69) in COVID-19 AN69-Oxiris, AN69-Standard - Covid19, AKI | Not applicable | Unknown | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 35 | 2020-10-02 | 2020-10-22 |
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Acute Kidney Injury (9) · COVID-19 (6) · Sepsis (4) · Coronavirus Infections (3) · Renal Insufficiency (3) · Liver Cirrhosis (2) · Renal Insufficiency, Chronic (2) · Respiratory Insufficiency (2) · Acute-On-Chronic Liver Failure (1) · Aortic Valve Stenosis (1) · Arrhythmias, Cardiac (1) · Ascites (1) · Atrial Fibrillation (1) · Chronic Kidney Disease-Mineral and Bone Disorder (1) · Critical Illness (1)
Pathologic Processes (15) · Pathological Conditions, Signs and Symptoms (15) · Female Urogenital Diseases (13) · Female Urogenital Diseases and Pregnancy Complications (13) · Kidney Diseases (13) · Male Urogenital Diseases (13) · Urogenital Diseases (13) · Urologic Diseases (13) · Infections (10) · Renal Insufficiency (9) · Cardiovascular Diseases (7) · Respiratory Tract Diseases (7) · Coronaviridae Infections (6) · Lung Diseases (6) · Nidovirales Infections (6)
Continuous Renal Replacement Therapy (2) · Blood Transfusion (1) · Dextrans (1) · Nitric Oxide (1) · Oxygen (1) · Pentoxifylline (1) · Polymorphism, Genetic (1) · Pterocarpus marsupium (1) · Radial Basis Function Networks (1) · Sodium Bicarbonate (1) · Standard of Care (1) · Viral Load (1) · nicotinamide-beta-riboside (1)
Assiut University (2) · Qianfoshan Hospital (2) · Bin Du (1) · Children's Hospital Medical Center, Cincinnati (1) · Chulalongkorn University (1) · First Affiliated Hospital Xi'an Jiaotong University (1) · G. d'Annunzio University (1) · Hamad Medical Corporation (1) · Hillerod Hospital, Denmark (1) · Hospital Universitari de Bellvitge (1) · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran (1) · Instituto Nacional de Enfermedades Respiratorias (1) · Mansoura University (1) · Mayo Clinic (1) · National University Hospital, Singapore (1)
United States (12) · China (5) · Italy (3) · Mexico (3) · Bolivia (2) · Canada (2) · Chile (2) · India (2) · Sweden (2) · United Kingdom (2) · Australia (1) · Brazil (1) · Colombia (1) · Denmark (1) · Dominican Republic (1)
Abhasnee Sobhonslidsuk, MD (1) · Ankit Sakhuja, MD (1) · Bernardo Mendes, MD (1) · Edward T Qian, MD (1) · Ian E McCoy, MD, MS (1) · Javier A Neyra, MD, MSCS (1) · John Peabody, MD, PhD (1) · Kristina Svennerholm, MD PhD (1) · Mahmoud Alhandi Omar Helal (1) · Mahmoud Helal (1) · Marco Zimarino, MD, PhD (1) · Ming Ann Sim (1) · Nitin V Kolhe, MD (1) · Qindong Shi, Chief (1)
PMID 11505124, PMID 16763508, PMID 19846848, PMID 20953964, PMID 24004539, PMID 29130845, PMID 29194145, PMID 29743094, PMID 29973706, PMID 30146969, PMID 32172242, PMID 32273593, PMID 33125416, PMID 33272037, PMID 33304914, PMID 33494766, PMID 33901787, PMID 34518032, PMID 36271419, PMID 36630406, PMID 36898748, PMID 37573366, PMID 37837651, PMID 37865685, PMID 37976391, PMID 38586479, PMID 38964736, PMID 39050483, PMID 39070183, PMID 39918882, PMID 41642325, PMID 41726007, PMID 42206788, PMID 42342404
2019 (1), K23DK128605 (1)