23 completed. 23 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 23 | Completed 23 |
Follow Agranulocytosis: new trials by email Literature Review of Agranulocytosis trials Research Report on Agranulocytosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stopping Antibiotics After 3 Days for the Treatment of High-risk FEbrile Neutropenia Comparison short vs extended EBAT treatment group - Neutropenia, Febrile | Phase 4 | Completed | Universitaire Ziekenhuizen KU Leuven | 450 | 2024-02-26 | 2026-10-23 |
| Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients Letermovir - Cytomegalovirus Infections, Infection in Solid Organ Transplant Recipients | Phase 4 | Completed | Tufts Medical Center | 21 | 2023-02-02 | 2026-10-26 |
| Letermovir Use in Heart Transplant Recipients Letermovir - Cytomegalovirus Disease, Cytomegalovirus Infections | Phase 4 | Completed | Tufts Medical Center | 32 | 2022-01-05 | 2025-07-29 |
| Early Versus Late Stopping of Antibiotics in Children With Cancer and High-risk Febrile Neutropenia Piperacillin and Tazobactam for Injection, Cefepime Injection, Ceftazidime Injection - Febrile Neutropenia | Phase 4 | Completed | Murdoch Childrens Research Institute | 55 | 2021-11-15 | 2026-03-20 |
| Efficacy and Safety of 4.5mg PEG-rhG-CSF Per Cycle in Preventing Neutropenia After Intensive Chemotherapy for Breast Cancer PEG-rhG-CSF - Breast Cancer, Neutropenia | Phase 4 | Completed | Peking University | 104 | 2019-08-01 | 2020-10-28 |
| Cefepime vs Ceftazidime as Empirical Therapy for Neutropenic Fever Ceftazidime Injection, Cefepime Injection - Neutropenia, Febrile, Leukemia | Phase 4 | Completed | Universitas Indonesia | 72 | 2019-03-01 | 2019-12-06 |
| Pneumococcal Vaccination of Multiple Myeloma Patients on Novel Agents Vaccination with pneumococcal conjugate vaccine (PCV13), Standard Antibacterial Prophylaxis - Multiple Myeloma, Pneumococcal Infection | Phase 4 | Completed | Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology | 36 | 2018-07-01 | 2022-08-31 |
| Steady-State Comparative Bioavailability Study in Prophylaxis Patients of Lozanoc® 50 mg With Sporanox® 100 mg Sporanox, Lozanoc - Neutropenia | Phase 4 | Completed | Mayne Pharma International Pty Ltd | 40 | 2015-11-01 | 2018-10-26 |
| Short Versus Extended Antibiotic Treatment With a Carbapenem for High-risk Febrile Neutropenia in Hematology Patients With FUO Discontinuation of imipenem-cilastatin or meropenem - Febrile Neutropenia, Hematological Malignancy | Phase 4 | Completed | Amsterdam UMC, location VUmc | 276 | 2014-12-01 | 2019-09-25 |
| Study to Reduce Duration of Antibiotic Therapy in Haematological Patients With Fever and Neutropenia Empirical antimicrobial treatment discontinuation, Standard empirical antimicrobial treatment discontinuation - Febrile Neutropenia | Phase 4 | Completed | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 157 | 2012-04-01 | 2017-11-01 |
| Comparison of the Pharmacodynamics of Imipenem in Patients With Febrile Neutropenia Imipenem - Patients With Febrile Neutropenia | Phase 4 | Completed | Prince of Songkla University | 12 | 2011-02-01 | 2014-08-11 |
| Pharmacokinetic/Pharmacodynamic Study of Doripenem in Febrile Neutropenic Patients Doripenem, doripenem - Febrile Neutropenia | Phase 4 | Completed | Gary E. Stein, Pharm.D. | 12 | 2010-08-01 | 2015-10-14 |
| Value of the LightCycler® SeptiFast Test MGRADE for the Pathogen Detection in Neutropenic Hematological Patients Detection of microbial DNA in blood by SeptiFast Test, Pathogen detection by blood culture - Hematologic Diseases, Neutropenia | Phase 4 | Completed | University Hospital Muenster | 150 | 2010-05-01 | 2012-12-05 |
| Safety of Cotrimoxazole in HIV- and HAART-exposed Infants cotrimoxazole - Acquired Immunodeficiency Syndrome, Infant, Newborn | Phase 4 | Completed | Harvard School of Public Health (HSPH) | 222 | 2009-02-01 | 2011-02-25 |
| Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections Detection of microbial DNA in blood by SeptiFast®, detection of microbial DNA in blood by blood culture - Febrile Neutropenia, Endocarditis | Phase 4 | Completed | Assistance Publique - Hôpitaux de Paris | 2000 | 2008-05-01 | 2011-12-29 |
| Oral Posaconazole in High Risk Patients With Gastrointestinal Dysfunction (Study P05115) Posaconazole - Fungal Infection, Acute Myelogenous Leukemia | Phase 4 | Completed | Merck Sharp & Dohme LLC | 75 | 2007-12-01 | 2017-04-07 |
| Antifungal Use in Oncohematological Neutropenic Patients Antifungal drug. VORICONAZOL. (VFEND®) - Invader Fungal Infection | Phase 4 | Completed | PETHEMA Foundation | 115 | 2006-08-01 | 2009-09-18 |
| Comparison of Teicoplanin and Vancomycin in Initial Empirical Antibiotic Regimen for Febrile Neutropenic Patients Teicoplanin, Vancomycin - Infection, Febrile Neutropenia | Phase 4 | Completed | Sanofi | 197 | 2005-01-01 | 2009-03-06 |
| FIRST - Study of Pegfilgrastim Administered in the First and Subsequent Cycles of Myelosuppressive Chemotherapy PI Discretion - Neutropenia | Phase 4 | Completed | Amgen | 2252 | 2004-05-01 | 2010-12-23 |
| Low-Dose Peginterferon and Ribavirin to Treat Chronic Hepatitis C in Patients Infected With HCV Genotype 2 or 3 Peginterferon alfa-2a, Ribavirin - Hepatitis C | Phase 4 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 58 | 2003-03-01 | 2013-12-06 |
Showing 20 of 23. Sign in to see all of them.
Neutropenia (18) · Febrile Neutropenia (11) · Neoplasms (6) · Fever (5) · Breast Neoplasms (2) · Cytomegalovirus Infections (2) · Infections (2) · Leukemia (2) · Sepsis (2) · Acquired Immunodeficiency Syndrome (1) · Anemia (1) · Anemia, Hemolytic (1) · Carcinoma, Non-Small-Cell Lung (1) · Endocarditis (1) · Fibrosis (1)
Cytopenia (23) · Hemic and Lymphatic Diseases (23) · Leukocyte Disorders (23) · Leukopenia (23) · Hematologic Diseases (22) · Infections (8) · Pathological Conditions, Signs and Symptoms (8) · Neoplasms (6) · Body Temperature Changes (5) · Neoplasms by Histologic Type (5) · Neutropenia (5) · Signs and Symptoms (5) · Neoplasms by Site (4) · Virus Diseases (4)
Cefepime (2) · Ceftazidime (2) · Cilastatin, Imipenem Drug Combination (2) · Vancomycin (2) · letermovir (2) · pegfilgrastim (2) · Amikacin (1) · Bulk Drugs (1) · Ciprofloxacin (1) · Doripenem (1) · Imipenem (1) · Injections (1) · Itraconazole (1) · Meropenem (1) · Piperacillin (1)
Amgen (3) · Tufts Medical Center (2) · Amsterdam UMC, location VUmc (1) · Assistance Publique - Hôpitaux de Paris (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Gary E. Stein, Pharm.D. (1) · Harvard School of Public Health (HSPH) (1) · Mayne Pharma International Pty Ltd (1) · Merck Sharp & Dohme LLC (1) · Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology (1) · Murdoch Childrens Research Institute (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Oslo University Hospital (1) · PETHEMA Foundation (1) · Peking University (1)
United States (4) · Australia (2) · Spain (2) · Belarus (1) · Belgium (1) · Botswana (1) · China (1) · France (1) · Germany (1) · Indonesia (1) · Netherlands (1) · Thailand (1) · Turkey (Türkiye) (1)
Anatoly Uss, MD/PhD (1) · Dag Torfoss, MD (1) · Deborah Marriott (1) · Edibe Taylan (1) · Gabrielle Haeusler (1) · Gary Stein, PharmD (1) · Jennifer K Chow, MD, MS (1) · Johan Maertens, MD, PhD (1) · Karsten Becker, MD, Professor (1) · Mark MH Kramer, Prof., MD (1) · Michiel A van Agtmael, MD, PhD (1)
PMID 17470691, PMID 17621407, PMID 18165618, PMID 20118030, PMID 20163377, PMID 22290953, PMID 24086319, PMID 28374097, PMID 29153975, PMID 32418789, PMID 35691326, PMID 39115709, PMID 40396505
2005 (1), 2014 (1), 2016 (1), P30AI060354 (1), R24TW007988 (1)