24 completed, 3 terminated, 3 unknown, 1 not yet recruiting. 19 Not applicable, 5 Phase 4, 2 Phase 3, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 19 | Completed 16, Terminated 2, Not yet recruiting 1 |
| Phase 4 | 5 | Completed 3, Unknown 2 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Abortion, Induced: new trials by email Literature Review of Abortion, Induced trials Research Report on Abortion, Induced
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| To Study the Safety and Efficacy of A Novel Intrauterine Estrogen-Releasing System in Induced Abortion Estradiol-Loaded Silicone Rubber Intrauterine Stent System, No-Drug-Loaded Silicone Rubber Intrauterine Stent System - Abortion, Induced | Not applicable | Not yet recruiting | Peking Union Medical College Hospital | 200 | 2026-03-01 | 2026-02-02 |
| Developing and Testing Interventions to Address Conscientious Objection to Abortion Care in Mexico and South Africa CO Intervention - Abortion, Induced, Abortion, Incomplete | Not applicable | Terminated | Ipas | 317 | 2020-02-13 | 2020-07-29 |
| Gabapentin for Pain Control After Osmotic Dilator Insertion and Prior to D&E Procedure: a Randomized Controlled Trial Gabapentin 600mg, Placebo oral capsule, acetaminophen/codeine and ibuprofen - Abortion, Induced, Cervical Preparation | Phase 4 | Completed | University of California, Davis | 121 | 2017-03-20 | 2020-04-14 |
| Different Routes of Misoprostol Prior to First Trimester Surgical Abortion Misoprostol (cytotec) - Abortion, Induced | Phase 4 | Unknown | Wolfson Medical Center | 120 | 2015-07-01 | 2016-04-29 |
| Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage of Labor After Second-trimester Abortion Oxytocin - Abortion, Induced, Labor Stage, Third/Drug Effects | Phase 4 | Completed | Ataturk University | 160 | 2015-06-08 | 2023-02-28 |
| Dilapan-S / Dilasoft E-Registry in Induced Abortion Dilapan-S - Abortion, Induced | Completed | Medicem International CR s.r.o. | 439 | 2015-03-01 | 2017-05-19 | |
| Misoprostol Dose and Timing Before Surgical Abortion at 13 to 16 Weeks' Gestation: a Randomized Trial Misoprostol 400 mcg 3 hours prior to procedure, Misoprostol 600 mcg 90 minutes prior to procedure - Abortion, Induced | Not applicable | Completed | Planned Parenthood of Greater New York | 118 | 2014-11-01 | 2021-04-26 |
| Misoprostol for Second Trimester Termination of Pregnancy Vaginal misoprostol, Buccal misoprostol - Abortion, Induced | Phase 3 | Completed | Ataturk University | 130 | 2014-01-01 | 2015-01-16 |
| Cervical Preparation Before Dilation and Evacuation Mifepristone, misoprostol, Osmotic dilators - Abortion, Induced | Not applicable | Completed | Planned Parenthood League of Massachusetts | 300 | 2013-01-01 | 2016-02-24 |
| Transvaginal Versus Transabdominal Digoxin Prior to Second-trimester Abortion Digoxin (transvaginal administration), Digoxin (transabdominal administration) - Abortion, Induced | Not applicable | Completed | University of California, Los Angeles | 60 | 2012-10-01 | 2017-01-13 |
| Intrauterine Lidocaine for Laminaria Lidocaine, Normal Saline - Abortion, Induced, Pain Management | Phase 1 | Completed | University of North Carolina, Chapel Hill | 72 | 2012-09-01 | 2014-05-14 |
| Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks Mifepristone, Hygroscopic cervical dilators, Misoprostol - Abortion, Induced | Not applicable | Completed | Stanford University | 50 | 2012-05-01 | 2024-02-13 |
| Cervical Priming Before Dilation & Evacuation Misoprostol, Laminaria - Abortion, Induced | Not applicable | Completed | Ibis Reproductive Health | 159 | 2012-05-01 | 2013-11-07 |
| Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14-21 Weeks LMP) Mifepristone+misoprostol, Placebo+Misoprostol - Abortion, Induced | Phase 3 | Terminated | Gynuity Health Projects | 20 | 2011-02-01 | 2011-11-08 |
| Mifepristone Plus Misoprostol Versus Misoprostol Alone for 2nd Trimester Abortion (14 - 21 Weeks Last Menstrual Period (LMP)) mifepristone+misoprostol, misoprostol+placebo - Abortion, Induced | Not applicable | Completed | Gynuity Health Projects | 238 | 2009-06-01 | 2014-02-20 |
| Pilot Study of the Addition of Osmotic Dilators to Preparation Prior to Labor Induction Abortion osmotic dilator insertion - Abortion, Induced | Not applicable | Terminated | Boston University | 4 | 2009-03-01 | 2011-07-08 |
| Evaluation of Different Anesthesia for Uterine Curettage Lidocaine, Propofol, Sevoflurane - Uterine Curettage, Abortion, Induced | Not applicable | Completed | Nanjing Medical University | 150 | 2008-08-01 | 2009-03-31 |
| Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14 - 21 Weeks LMP): A Randomized-controlled Double-blinded Trial mifepristone+misoprostol, misoprostol, placebo - Abortion, Induced | Not applicable | Completed | Gynuity Health Projects | 120 | 2008-08-01 | 2014-02-20 |
| Paracervical Versus Intracervical Lidocaine Paracervical block, Intracervical, Buffered Lidocaine, vasopressin, sodium bicarbonate - Abortion, Induced, Pain | Not applicable | Completed | University of California, San Diego | 89 | 2007-12-01 | 2019-08-13 |
| Study of 400mcg Sublingual Versus 400mcg Buccal Misoprostol Following 200mg Mifepristone for Medical Abortion up to 63 Days Last Menstrual Period (LMP) Misoprostol - Abortion, Induced | Not applicable | Completed | Gynuity Health Projects | 550 | 2007-07-01 | 2009-03-27 |
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Neoplasm Metastasis (3) · Agnosia (2) · Dilatation, Pathologic (2) · Pain (2) · Abortion, Incomplete (1) · Abortion, Spontaneous (1) · Vomiting (1)
Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (5) · Neurologic Manifestations (4) · Neoplasms (3) · Neoplastic Processes (3) · Pathologic Processes (3) · Female Urogenital Diseases and Pregnancy Complications (2) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Pathological Conditions, Anatomical (2) · Perceptual Disorders (2) · Pregnancy Complications (2) · Urogenital Diseases (2) · Abortion, Spontaneous (1) · Signs and Symptoms, Digestive (1)
Misoprostol (11) · Mifepristone (5) · Acetaminophen (2) · Lidocaine (2) · Administration, Buccal (1) · Anesthesia, Obstetrical (1) · Ascorbic Acid (1) · Carboxymethylcellulose Sodium (1) · Codeine (1) · Digoxin (1) · Doxycycline (1) · Gabapentin (1) · Ibuprofen (1) · Ketoprofen (1) · Oxytocin (1)
Gynuity Health Projects (5) · Boston University (3) · Ataturk University (2) · University of Pittsburgh (2) · Atrium Medical Center (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dartmouth-Hitchcock Medical Center (1) · Ibis Reproductive Health (1) · Ipas (1) · Medicem International CR s.r.o. (1) · Nanjing Medical University (1) · Peking Union Medical College Hospital (1) · Planned Parenthood League of Massachusetts (1) · Planned Parenthood of Greater New York (1) · Stanford University (1)
United States (13) · China (3) · Moldova (2) · South Africa (2) · Turkey (Türkiye) (2) · France (1) · Israel (1) · Mexico (1) · Netherlands (1) · Puerto Rico (1) · Tunisia (1) · Vietnam (1)
Beverly Winikoff (2) · Beverly Winikoff, MD, MPH (2) · Lynn Borgatta, MD, MPH (2) · Beverly Winkoff, M.D., M.P.H (1) · Christine Monrigal, MD (1) · Emmanuel Mucci, MD (1) · Erin Pearson, PhD, MPH (1) · F Roumen, Dr. (1) · Gillian Dean, MD, MPH (1) · Hadas Ganer Herman, MD (1) · Ilana Dzuba, MHS (1) · Jane Harries, PhD (1) · Jean Claude Granry, MD (1) · Jiri Hanacek, MD (1)
PMID 17963864, PMID 18055725, PMID 18165398, PMID 19037040, PMID 21860289, PMID 24929888, PMID 25139724, PMID 25896965, PMID 26181087, PMID 26196084, PMID 31029655, PMID 34061352, PMID 37396569