38 completed, 1 terminated. 39 Phase 3, 9 Phase 2.
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All 39 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix .
Trial Phase Status Sponsor Enrollment Start Updated
A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With Gout Dotinurad, Febuxostat, Dotinurad Matched Placebo - Gout Phase 3 Completed 451 2021-12-21 2025-07-30 A Study of Lemborexant in Chinese Participants With Insomnia Disorder Lemborexant, Placebo - Sleep Initiation and Maintenance Disorders Phase 3 Completed 194 2020-11-06 2024-12-20 Clinical Trial of Ultra-high Dose Methylcobalamin for ALS methylcobalamin, saline solution - Amyotrophic Lateral Sclerosis Phase 3 Completed 130 2017-11-01 2025-03-26 A Study to Compare Eribulin Mesylate + Pertuzumab + Trastuzumab With Paclitaxel or Docetaxel + Pertuzumab + Trastuzumab Pertuzumab, Trastuzumab, Docetaxel - Breast Cancer Phase 3 Completed 446 2017-08-28 2025-09-29 Study for Verification of Efficacy and Safety for Perampanel Monotherapy in Untreated Participants With Partial Onset Seizures (Including Secondarily Generalized Seizures (FREEDOM Study) E2007 - Partial Onset Seizures Phase 3 Completed 91 2017-06-28 2021-08-05 A Trial of Lenvatinib (E7080) in Radioiodine (131 I)-Refractory Differentiated Thyroid Cancer in China Lenvatinib, Placebo - Differentiated Thyroid Cancer (DTC) Phase 3 Completed 151 2017-01-11 2022-01-26 A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Participants With Early Alzheimer's Disease Elenbecestat, Placebo - Alzheimer's Disease Phase 3 Terminated 2212 2016-10-20 2021-02-03 An Open-label Extension Study to Evaluate the Safety and Tolerability of Perampanel (E2007) Administered as an Adjunctive Therapy in Epilepsy Subjects Perampanel - Epilepsy Phase 3 Completed 7 2015-05-12 2018-07-02 Eribulin Versus Vinorelbine in Subjects With Locally Recurrent or Metastatic Breast Cancer Previously Treated With Anthracyclines and Taxanes E7389 (Eribulin Mesylate), Vinorelbine injection - HER2-Negative Breast Cancer, Triple Negative Breast Cancer Phase 3 Completed 530 2013-09-26 2018-08-28 A Double-blind Comparative Study of the Efficacy and Safety of E3810 10mg Once and Twice Daily in Maintenance Therapy for PPI Resistant Gastroesophageal Reflux Disease Patients Rabeprazole - Gastroesophageal Reflux Disease Phase 3 Completed 517 2013-09-01 2023-06-22 A Multicenter, Open-label Study for E7040 in Japanese Subjects With Hypervascular Tumor and Subjects With Arteriovenous Malformation E7040 - Hypervascular Tumor and Arteriovenous Malformation Phase 3 Completed 28 2012-08-01 2016-02-22 A Study With an Open-label Extension Phase to Evaluate the Efficacy and Safety of Perampanel (E2007) Administered as an Adjunctive Therapy in Subjects With Refractory Partial-onset Seizures Perampanel, Placebo - Partial-onset Seizures Phase 3 Completed 940 2012-05-15 2021-07-29 Compare the Efficacy and Safety of Donepezil Hydrochloride 23 mg Treatment With Continuation of Donepezil Hydrochloride 10 mg Treatment in Japanese Subjects With Severe Alzheimer's Disease E2020 - Alzheimer's Type Dementia Phase 3 Completed 351 2012-03-01 2023-06-18 Long-term Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study) Rabeprazole - Gastric Ulcers Duodenal Ulcers Caused by Low-dose Aspirin Phase 2 / Phase 3 Completed 405 2011-12-01 2015-12-21 Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study) E3810, Teprenone - Gastric or Duodenal Ulcers Caused by Low-dose Aspirin Phase 2 / Phase 3 Completed 472 2011-07-01 2014-11-26 A Clinical Trial to Study the Effects of a Fixed Dose Combination of Diclofenac and Eperisone Hydrochloride With Plain Eperisone Hydrochloride in Patients With Low Back Pain Eperisone hydrochloride and Diclofenac sodium, Eperisone hydrochloride - Acute Musculoskeletal Spasm Due to Low Back Pain Phase 3 Completed 239 2011-02-01 2013-01-08 A Study of E2020 in Patients With Dementia With Lewy Bodies (DLB), Followed by a Long-term Extension Phase Donepezil 5 mg, Donepezil 10 mg, Donepezil matched placebo - Dementia With Lewy Bodies (DLB) Phase 3 Completed 142 2011-02-01 2023-06-29 A Long Term Extension Study of E2080 in Lennox-Gastaut Patients Rufinamide - Lennox-Gastaut Syndrome Phase 3 Completed 54 2010-11-01 2019-03-11 A Study of Adalimumab in Japanese Subjects With Intestinal Behçet's Disease Adalimumab - Intestinal Behçet's Disease Phase 3 Completed 20 2010-10-01 2014-07-25 An Study of Efficacy and Safety of Clevudine Clevudine, Adefovir - Chronic Hepatitis B Phase 3 Completed 288 2010-02-01 2013-05-14
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Conditions studied Arthritis, Rheumatoid (4) · Amyotrophic Lateral Sclerosis (3) · Dementia (3) · Epilepsy (3) · Sleep Initiation and Maintenance Disorders (3) · Alzheimer Disease (2) · Breast Neoplasms (2) · Cognitive Dysfunction (2) · Crohn Disease (2) · Duodenal Ulcer (2) · Gastroesophageal Reflux (2) · Muscular Atrophy (2) · Osteoporosis (2) · Seizures (2) · Stomach Ulcer (2)
Interventions Adalimumab (10) · Rabeprazole (5) · mecobalamin (3) · perampanel (3) · Donepezil (2) · Eszopiclone (2) · eperisone (2) · eribulin (2) · Aging (1) · Diclofenac (1) · Docetaxel (1) · Febuxostat (1) · Paclitaxel (1) · Saline Solution (1) · T 614 (1)
Countries Japan (30) · China (7) · South Korea (3) · Australia (2) · India (2) · Taiwan (2) · United States (2) · Argentina (1) · Austria (1) · Bulgaria (1) · Canada (1) · Czechia (1) · France (1) · Germany (1) · Greece (1)
Top investigators Nobuyuki Sugisaki (3) · Atsushi Kamijo (2) · Kazuko Kobayashi (2) · Kazunori Saeki (2) · Morio Ozawa, MS (2) · Shigeki Hashimoto, PhD (2) · Dr. Dilip Pawar (1) · Guoping Yang (1) · Hideyuki Hashiba, BS (1) · Hiroki Takano (1) · Hiroshi Ukai, BS (1) · Hong Di (1) · Kota Nagai (1) · Masaki Nakagawa (1) · Morio Ozawa (1)
Results publications PMID 22325170 , PMID 25982504 , PMID 20881072 , PMID 21376385 , PMID 22149875 , PMID 22731653 , PMID 23053683 , PMID 23063301 , PMID 24441150 , PMID 24874893 , PMID 25024001 , PMID 25245624 , PMID 25605862 , PMID 25713599 , PMID 25713600 , PMID 27338778 , PMID 28670237 , PMID 29188387 , PMID 29250772 , PMID 30054164 , PMID 30578206 , PMID 30636701 , PMID 30928806 , PMID 32381018 , PMID 34326132 , PMID 34657389 , PMID 35532908 , PMID 35897078 , PMID 35909569 , PMID 37059702 , PMID 38087949 , PMID 38940656 , PMID 39787453 , PMID 41442783 , PMID 41475066 , PMID 42420599 , PMID 9843082
NIH funding 2016 (1)