12 completed, 2 active not recruiting, 2 terminated, 2 withdrawn. 19 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 19 | Completed 12, Active not recruiting 2, Terminated 2, Withdrawn 2, Unknown 1 |
Follow Sugars: new trials by email Literature Review of Sugars trials Research Report on Sugars
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences Naltrexone Hydrochloride, Placebo - Naltrexone, Placebo | Early Phase 1 | Completed | San Diego State University | 217 | 2021-11-16 | 2026-09-10 |
| Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity Carbamazepine, Lorazepam, Dextromethorphan - Low Intensity Focussed Ultrasound | Early Phase 1 | Active not recruiting | University Health Network, Toronto | 20 | 2021-05-25 | 2025-08-03 |
| Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients Midodrine, Placebo pill, Abdominal compression - Neurogenic Orthostatic Hypotension, Autonomic Failure | Early Phase 1 | Completed | Vanderbilt University Medical Center | 31 | 2020-11-09 | 2026-08-07 |
| Fluoxetine Prevention Trial Fluoxetine, Placebo - Cognitive Dysfunction | Early Phase 1 | Withdrawn | University of California, Los Angeles | 2018-06-01 | 2018-10-15 | |
| Glucocorticoid Antagonist Treatment for Tobacco Use Disorder Mifepristone, Placebo - Nicotine Dependence | Early Phase 1 | Terminated | Yale University | 8 | 2017-11-29 | 2019-05-28 |
| Acupuncture for Pain in the Emergency Department Auricular Acupuncture, Acupuncture, Placebo Acupuncture - Musculoskeletal Pain, Pain | Early Phase 1 | Withdrawn | Loma Linda University | 2017-07-27 | 2017-07-28 | |
| Topiramate Augmenting Strategies for the Treatment of Alcohol Use Disorder Topiramate and N-Acetyl Cysteine, Topiramate and Placebo - Alcoholism | Early Phase 1 | Completed | Nassima Ait-Daoud Tiouririne | 17 | 2017-05-01 | 2026-05-27 |
| Assess Efficacy of of Oral Treprostinil in Patients With Symptomatic Primary or Secondary Raynaud's Phenomenon oral treprostinil, Placebo - Raynaud's Phenomenon | Early Phase 1 | Completed | Brigham and Women's Hospital | 12 | 2016-05-01 | 2022-01-10 |
| Study of Loratadine for Pegfilgrastim Induced Bone Pain in Patients With Aggressive Lymphoma Pegfilgrastim, Loratadine, Placebo - Lymphoma | Early Phase 1 | Terminated | M.D. Anderson Cancer Center | 1 | 2015-12-14 | 2019-04-23 |
| The Effects of L-Tyrosine on 24 Hour Blood Pressure and Heart Rate in Parkinson's Disease L-tyrosine, Sugar Pill - Blood Pressure | Early Phase 1 | Completed | New York Institute of Technology | 6 | 2014-10-01 | 2016-01-20 |
| Periodontal and Cardiometabolic Responses to Vitamin D Intervention in African Americans With Periodontal Disease Cholecalciferol, Placebo - Periodontal Disease, Vitamin D Deficiency | Early Phase 1 | Unknown | Augusta University | 24 | 2014-04-01 | 2015-01-13 |
| Memantine for Enhanced Stroke Recovery Memantine XR, Placebo (for memantine) - Ischemic Stroke, Upper Extremity Weakness | Early Phase 1 | Active not recruiting | University of Utah | 20 | 2014-01-01 | 2026-08-27 |
| Enhancing Panic and Smoking Reduction Treatment With D-Cycloserine d-cycloserine, Pill Placebo, Nicotine replacement therapy - Nicotine Addiction, Panic Attack | Early Phase 1 | Completed | University of Texas at Austin | 53 | 2013-10-01 | 2021-05-19 |
| Study of the Microbiota, Metabolome, and Environmental Toxins in Relation to Reproductive Health in Rwandan Women Lactobacillus GR-1 and Lactobacillus RC-14 oral capsules, Placebo - Vulvovaginal Candidiasis, Bacterial Vaginosis | Early Phase 1 | Completed | Western University, Canada | 30 | 2012-09-01 | 2014-05-30 |
| Valproic Acid in Subjects With Intact Cognition - Proof of Concept Study Valproic Acid, Placebo - Alzheimer's Disease | Early Phase 1 | Completed | Gregory Jicha, 323-5550 | 14 | 2012-04-01 | 2019-10-09 |
| The Effect of Eszopiclone on the Arousal Threshold in Sleep Apnea Syndrome Eszopiclone, Placebo - Obstructive Sleep Apnea | Early Phase 1 | Completed | Brigham and Women's Hospital | 17 | 2009-01-01 | 2017-04-18 |
| Dose-dependent Anti-inflammatory Effects of Vitamin D in a Human Gingivitis Model vitamin D3, Placebo - Gingivitis | Early Phase 1 | Completed | Boston University | 35 | 2008-12-01 | 2017-10-02 |
| D-Cycloserine Augmentation of Behavior Therapy for Individuals With Body Dysmorphic Disorder d-cycloserine, Placebo - Body Dysmorphic Disorder | Early Phase 1 | Completed | Massachusetts General Hospital | 68 | 2008-11-01 | 2019-06-18 |
| A Clinical Trial of Ginseng in Diabetes Ginseng, ginsenoside RE, Placebo (sugar pill) - Diabetes | Early Phase 1 | Completed | Washington University School of Medicine | 19 | 2003-09-01 | 2019-09-09 |
Periodontal Diseases (2) · Tobacco Use Disorder (2) · Alcoholism (1) · Alzheimer Disease (1) · Behavior, Addictive (1) · Body Dysmorphic Disorders (1) · Burkitt Lymphoma (1) · Candidiasis, Vulvovaginal (1) · Cognitive Dysfunction (1) · Diabetes Mellitus (1) · Gingivitis (1) · Inflammation (1) · Ischemic Stroke (1) · Lymphoma (1) · Lymphoma, Extranodal NK-T-Cell (1)
Brigham and Women's Hospital (2) · Augusta University (1) · Boston University (1) · Gregory Jicha, 323-5550 (1) · Loma Linda University (1) · M.D. Anderson Cancer Center (1) · Massachusetts General Hospital (1) · Nassima Ait-Daoud Tiouririne (1) · New York Institute of Technology (1) · San Diego State University (1) · University Health Network, Toronto (1) · University of California, Los Angeles (1) · University of Texas at Austin (1) · University of Utah (1) · Vanderbilt University Medical Center (1)
United States (16) · Canada (1) · Rwanda (1)
Aaron Waxman, MD/PhD (1) · Alicia Bennett, D.O. (1) · Atul Malhotra, MD (1) · Daniel H. Silverman, M.D., Ph.D. (1) · Gregor Dr Reid, PhD (1) · Gregory Jicha, MD (1) · Jason R. Westin, MD (1) · Jennifer Majersik, M.D. (1) · Joanne Donoghue, PhD (1) · Kenneth S Polonsky, MD (1) · Luis Okamoto, MD (1) · Mehmet Sofuoglu, M.D.,Ph.D. (1) · Nassima Ait-Daoud Tiouririne, M.D. (1) · Paul Dellaripa, MD (1) · Raul I Garcia, DMD (1)
PMID 21269278, PMID 21411505, PMID 29912913, PMID 32004998
P01HL095491 (1), R01DA052883 (1), R01HL144568 (1), R21AT003714 (1)