134 completed, 23 terminated, 7 unknown, 7 withdrawn. 178 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 178 | Completed 134, Terminated 23, Unknown 7, Withdrawn 7, Enrolling by invitation 2, Not yet recruiting 2, Recruiting 2, Active not recruiting 1 |
Follow Sugars: new trials by email Literature Review of Sugars trials Research Report on Sugars
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Crossover Study Evaluating the Postprandial Glycemic Response of Three Sweeteners in a Mixed Meal Setting LOAM Fiber-based Sweetener, Sugar, Stevia - Postprandial Glucose, GI Tolerance | Not applicable | Not yet recruiting | LOAM Science | 50 | 2026-12-01 | 2026-10-26 |
| Evaluating the Impact of Fat and Sugar Replacer Blends on Gastrointestinal Tolerance in Biscuits Test sandwiched biscuits with creme, Control sandwiched biscuit with sugar - Gastrointestinal Tolerance, Healthy Population | Not applicable | Completed | Mondelēz International, Inc. | 56 | 2025-10-28 | 2026-03-27 |
| Effect of Use of Probiotics on Systemic Infection in Critically Ill Patients: a Double Blind, Randomized, Placebo-controlled Trial Bacillus clausii, Sugar tablets - Ventilator Acquired Pneumonia, Catheter Related Bloodstream Infection | Not applicable | Enrolling by invitation | Benha University | 100 | 2025-04-01 | 2025-09-10 |
| GRAPE-GDM Prospective Comperative Trial - Grape Juice as a Replacement Drink for Gestational Diabetes Screening Participants will consume 500 ml of commercially available grape juice which contains 50g of sugar, serving as an alternative glucose load. - Pregnancy - Prenatal Testing | Not applicable | Enrolling by invitation | Bnai Zion Medical Center | 150 | 2025-02-19 | 2026-01-07 |
| PNF Versus Cryotherapy in Delayed Onset Muscle Soreness Proprioceptive Neuromuscular Facilitation, Local Cryotherapy, Placebo: Water With Sugar - Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Universidad Pontificia de Salamanca | 29 | 2025-01-01 | 2026-06-16 |
| Efficacy of Recombinant Bovine Lactoferrin (rbLf) in Iron Regulation Recombinant Bovine Lactoferrin, Bovine Milk-Derived Lactoferrin, Placebo - Exercise Performance | Not applicable | Completed | University of North Carolina, Chapel Hill | 92 | 2024-07-05 | 2025-09-17 |
| Reducing Salt and Sugar in Campus Foods: A Malaysian Study Reduction in Salt and Sugar, The potentiometer, Dry Ashing Method Followed by Flame Atomic Absorption Spectrometry (FAAS) - Cardiovascular Diseases | Not applicable | Not yet recruiting | Sunway University | 300 | 2024-07-01 | 2024-06-25 |
| Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis open-label placebo, Treatment as usual - Adolescent Idiopathic Scoliosis (AIS) | Not applicable | Recruiting | University of California, San Francisco | 64 | 2024-07-01 | 2026-03-13 |
| Creatine Monohydrate for Mild Traumatic Brain Injury: a Randomised Controlled Pilot Study Creatine Monohydrate, Sugar Pill (Placebo) - Mild Traumatic Brain Injury, Concussion (Diagnosis) | Not applicable | Completed | University of Southern Denmark | 34 | 2023-08-01 | 2026-04-07 |
| The Effect of Sugar Load in IBS Patients Depending on Sucrase-isomaltase Genes Sugar - Sucrase-Isomaltase Deficiency, Irritable Bowel Syndrome | Not applicable | Completed | Region Skane | 40 | 2023-01-04 | 2025-06-27 |
| The Impact of Steviol Glycosides on Human Gut Microflora Profile and Function Sucrose, Steviol Glycosides - Healthy, Human Gut Microflora | Not applicable | Completed | Cargill | 59 | 2022-02-15 | 2023-04-28 |
| Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms Accelerometer, placebo pill, Midodrine or atomoxetine pill - Orthostatic; Hypotension, Neurogenic, Autonomic Failure | Not applicable | Recruiting | Vanderbilt University Medical Center | 29 | 2021-02-05 | 2026-07-02 |
| Effectiveness of SNF and SBCC to Prevent Stunting Among Children in Afghanistan: a Quasi-experimental Study Super Cereal - wheat soya blend with sugar, Lipid-based nutrient supplement-medium quantity (LNS-MQ), Social and behavior change communication (SBCC) - Stunting, Malnutrition, Child | Not applicable | Completed | Aga Khan University | 33100 | 2021-02-01 | 2023-08-16 |
| Analgesia in Lingual Frenulotomy in the Newborn Sugar and water solution, Sterile water - Frenulum Breve | Not applicable | Completed | IRCCS Burlo Garofolo | 72 | 2020-09-18 | 2025-05-07 |
| Sweeteners and Sweetness Enhancers: Prolonged Effects on Health, Obesity and Safety S&SEs, Sugar - Obesity | Not applicable | Completed | Anne Birgitte Raben | 379 | 2020-01-30 | 2022-11-01 |
| Optimizing Overactive Bladder Treatment Lactobacillus Probiotic Capsule, Matching Lactobacillus Probiotic Placebo Capsule - Overactive Bladder | Not applicable | Completed | University of North Carolina, Chapel Hill | 29 | 2019-06-01 | 2020-05-11 |
| Effects of A-GPC on Reaction Time and Cognitive Function A-GPC, Sugar - Cognitive Change, Reaction Time | Not applicable | Completed | University of Mary Hardin-Baylor | 18 | 2019-03-25 | 2020-11-12 |
| Acute Effects of Oral Carbohydrate and Fat Loads on Systemic Microvascular Endothelial Function in Healthy Individuals. sugar oral load, fat oral load, sugar and fat oral load - Metabolic Syndrome | Not applicable | Completed | National Institute of Cardiology, Laranjeiras, Brazil | 60 | 2018-12-10 | 2024-03-26 |
| Vitamin C Supplementation Intervention Vitamin C 500 mg, Vitamin C 1000 mg, Placebo - Heart Failure | Not applicable | Completed | University of North Carolina, Chapel Hill | 36 | 2018-08-14 | 2021-03-09 |
| Effects of a Thermogenic Dietary Supplement on Metabolic, Hemodynamic, and Mood Responses Sugar Pill (placebo), Caffeine (plus Teacrine and Cayenne), Caffeine (plus Teacrine) - Energy Metabolism, Heart Rate | Not applicable | Completed | University of Mary Hardin-Baylor | 14 | 2018-07-23 | 2019-03-28 |
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Pain (8) · Inflammation (7) · Behavior, Addictive (6) · Insulin Resistance (6) · Cocaine-Related Disorders (5) · Metabolic Syndrome (5) · Stress Disorders, Post-Traumatic (5) · Diabetes Mellitus (4) · Diabetes Mellitus, Type 2 (4) · Hypertension (4) · Obesity (4) · Pulmonary Disease, Chronic Obstructive (4) · Agnosia (3) · Alcoholism (3) · Asthma (3)
Yale University (11) · University of Mary Hardin-Baylor (5) · University of Miami (5) · Stanford University (4) · University of North Carolina, Chapel Hill (4) · M.D. Anderson Cancer Center (3) · Milton S. Hershey Medical Center (3) · Oregon Health and Science University (3) · University of California, Davis (3) · University of Florida (3) · University of Pittsburgh (3) · Washington University School of Medicine (3) · Weill Medical College of Cornell University (3) · Brigham and Women's Hospital (2) · Fred Hutchinson Cancer Center (2)
United States (124) · Canada (10) · Brazil (4) · Israel (4) · Netherlands (4) · Denmark (3) · Spain (3) · Sweden (3) · France (2) · Germany (2) · Italy (2) · Afghanistan (1) · Australia (1) · China (1) · Egypt (1)
Mehmet Sofuoglu, M.D., Ph.D. (6) · Hugh Brent Solvason (3) · Lemuel W Taylor IV, PhD (3) · Adam Wanner, MD (2) · Italo Biaggioni, MD (2) · John Lewis, Ph.D. (2) · Kathryn Chung, MD (2) · Kimber L Stanhope, Ph.D, R.D. (2) · Lemuel W Taylor, PhD (2) · Manyat Nantha-Aree, MD (2) · Murray Raskind, MD (2) · Peter N Schlegel, MD (2) · Abbie Smith-Ryan, PhD (1) · Alexis Dieter, MD (1) · Ali Alaraj, MD (1)
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R01DA014537 (2), 2009 (1), K23HL076468 (1), K23HL080231 (1), K23MH106037 (1), P01HL095491 (1), P20AA017839 (1), P20HL113444 (1), P50DA009241 (1), P50DA018197 (1), R01AA013307 (1), R01DA021264 (1), R01DA029577 (1), R01DA036564 (1), R01DK073411 (1)