29 completed, 3 withdrawn, 2 terminated, 1 recruiting. 37 Phase 2, 4 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 37 | Completed 29, Withdrawn 3, Terminated 2, Recruiting 1, Suspended 1, Unknown 1 |
| Phase 1 | 4 | Completed 3, Withdrawn 1 |
| Phase 3 | 3 | Completed 3 |
Follow Placebo Patch: new trials by email Literature Review of Placebo Patch trials Research Report on Placebo Patch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Transdermal Ethinyl Estradiol and Norelgestromin for Irregular Bleeding in Contraceptive Implant Users Transdermal Ethinyl Estradiol/Norelgestromin Patch, Placebo Patch - Menstruation Disturbances, Metrorrhagia | Phase 2 | Recruiting | Chulalongkorn University | 40 | 2025-07-29 | 2025-12-10 |
| The Use of Cannabinoid Patch for Knee Osteoarthritis Topical CBD Patch, Placebo Patch - Knee Osteoarthritis, CBD | Phase 2 | Withdrawn | Northwell Health | 2022-10-01 | 2023-01-19 | |
| Evaluation of the Dexmedetomidine Transdermal Systems for Postoperative Analgesia Following Abdominoplasty DMTS Patch, Placebo Patch - Pain, Postoperative | Phase 2 | Terminated | Teikoku Pharma USA, Inc. | 179 | 2022-07-07 | 2025-12-24 |
| Impact of Alternative Nicotine-Delivery Products on Combustible Cigarette Use Juul Electronic cigarette, Very Low Nicotine Cigarettes, Active Nicotine Patch - Nicotine Dependence | Phase 2 | Completed | University of Wisconsin, Madison | 209 | 2020-09-09 | 2023-05-25 |
| The Role of Estrogen in the Neurobiology of Eating Disorders 17-β estradiol transdermal patches, Placebo Patch, Micronized progesterone 200 MG - Eating Disorders, Hypoestrogenemia | Phase 2 | Completed | Massachusetts General Hospital | 122 | 2019-06-13 | 2026-11-05 |
| The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products Nicotine patch, Placebo patch, E-cigarettes - Nicotine Dependence, Cigarettes | Phase 2 | Completed | Duke University | 94 | 2018-08-06 | 2023-02-08 |
| Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment Nicotine patch, ENDS, Placebo patch - Nicotine Dependence | Phase 2 | Withdrawn | Duke University | 2018-07-01 | 2018-09-12 | |
| Herbal Patch for Overactive Bladder herbal patch, placebo patch - Overactive Bladder Syndrome | Phase 2 / Phase 3 | Completed | En Chu Kong Hospital | 66 | 2018-05-14 | 2019-10-25 |
| A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis Diclofenac Sodium Active Topical Patch 1, Diclofenac Sodium Active Topical Patch 2, Placebo patch - Osteoarthritis of the Knee | Phase 2 | Completed | Noven Pharmaceuticals, Inc. | 289 | 2017-09-07 | 2021-12-23 |
| Memory Improvement Through Nicotine Dosing (MIND) Study Nicotine Transdermal Patch, Placebo Patch - Mild Cognitive Impairment | Phase 2 | Completed | University of Southern California | 348 | 2017-02-22 | 2026-09-17 |
| Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair Buprenorphine, Placebo Patch, Multimodal Oral Scheme - Rotator Cuff Tear, Rotator Cuff Injury | Phase 2 / Phase 3 | Completed | Hospital Italiano de Buenos Aires | 50 | 2016-09-22 | 2021-04-08 |
| Milk Patch for Eosinophilic Esophagitis Viaskin Milk 500 mcg, Viaskin Placebo - Eosinophilic Esophagitis, Milk Allergy | Phase 2 | Completed | Children's Hospital of Philadelphia | 20 | 2015-10-01 | 2019-07-10 |
| Pilot Study Comparing the Efficacy and Safety of a New Pain Patch and Placebo in Delayed Onset Muscle Soreness (DOMS) Loxoprofen Pain Patch, Placebo Patch, No Treatment - Delayed Onset Muscle Soreness | Phase 2 | Completed | Lead Chemical Co., Ltd. | 42 | 2015-10-01 | 2016-10-28 |
| A Study of a Topical Patch (AB001) in Patients With Chronic Low Back Pain AB001 patch, Placebo patch - Chronic Low Back Pain | Phase 2 | Completed | Frontier Biotechnologies Inc. | 146 | 2015-04-01 | 2016-08-30 |
| Study to Evaluate Safety & Efficacy of d-Amphetamine Transdermal System vs Placebo in Children & Adolescents With ADHD d-Amphetamine Transdermal Patch, Placebo patch - Attention Deficit Hyperactivity Disorder | Phase 2 | Completed | Noven Pharmaceuticals, Inc. | 110 | 2012-10-01 | 2023-12-21 |
| Safety & Efficacy Study of HTU-520 in the Treatment of Distal Subungual Onychomycosis of the Toenail HTU-520 Patch, Placebo Patch - Onychomycosis | Phase 2 | Completed | Hisamitsu Pharmaceutical Co., Inc. | 182 | 2011-07-01 | 2015-06-04 |
| Acne Treatment With Active Oplon's Patches - 15-18 Years Old Oplon Active Patch, Placebo Patch - Acne Vulgaris | Phase 2 | Unknown | Oplon-Pure Science Ltd. | 50 | 2011-01-01 | 2010-12-17 |
| Acne Treatment With Active Oplon's Patches Oplon Active Patch, Placebo Patch - Acne Vulgaris | Phase 2 | Completed | Oplon-Pure Science Ltd. | 40 | 2010-08-01 | 2011-06-10 |
| Comparison of Synera Patch Versus LMX-4 Cream Versus Placebo Patch for Pain Reduction During Venipuncture in Children Synera Patch, LMX 4 Cream, Placebo Patch - Pain, Venipuncture | Phase 2 | Completed | Carol Morreale | 150 | 2010-04-01 | 2014-02-04 |
| Study of the Efficacy and Safety of Bupivacaine TTS Patch in Patients With Chronic Low Back Pain Bupivacaine TTS (Bupivacaine Patch), Placebo patch - Chronic Low Back Pain | Phase 2 | Completed | Durect | 263 | 2010-03-01 | 2022-06-15 |
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Tobacco Use Disorder (6) · Osteoarthritis, Knee (5) · Pain (4) · Osteoarthritis (3) · Acne Vulgaris (2) · Alzheimer Disease (2) · Chronic Pain (2) · Cigarette Smoking (2) · Vaping (2) · Amenorrhea (1) · Anorexia Nervosa (1) · Attention Deficit Disorder with Hyperactivity (1) · Behavior (1) · Cognitive Dysfunction (1) · Contraception Behavior (1)
Duke University (2) · Endo USA Inc., a Keenova Therapeutics Company (2) · Hisamitsu Pharmaceutical Co., Inc. (2) · Massachusetts General Hospital (2) · National Institute on Drug Abuse (NIDA) (2) · Noven Pharmaceuticals, Inc. (2) · Oplon-Pure Science Ltd. (2) · Teikoku Pharma USA, Inc. (2) · University of Wisconsin, Madison (2) · ZARS Pharma Inc. (2) · Carol Morreale (1) · Children's Hospital of Philadelphia (1) · Chulalongkorn University (1) · Durect (1) · En Chu Kong Hospital (1)
United States (28) · Israel (3) · Argentina (1) · South Korea (1) · Switzerland (1) · Taiwan (1) · Thailand (1)
Avner Shemer, M.D. (2) · Antonella Cianferoni, MD, PhD (1) · Boni Elewski, MD (1) · Changjin Wang (1) · Daniel G. Lorch, MD (1) · David Bolshoun, MD (1) · Derek Muse, MD (1) · Donald Sislen, MD (1) · Douglas N. Robins, MD (1) · Elbert D Glover, Ph.D. (1) · Elizabeth McFarland, MD (1) · Ernest A. Kopecky, PhD, MBA (1) · Francisco A. Kerdel, MD (1) · Frank Farmer, Jr, MD (1)
PMID 37230961, PMID 19339135, PMID 21846661, PMID 28044059, PMID 28158151, PMID 28416813, PMID 28786978, PMID 30184299, PMID 31100455, PMID 31810978, PMID 34035477, PMID 35020462, PMID 37339441, PMID 38348917, PMID 40294815, PMID 40803048
P50DA027840 (2), R01AG013241 (1), R01AG017196 (1), R01AG047992 (1), R01CA239309 (1), R01DA015365 (1), R01MH116205 (1)