21 completed, 3 unknown, 1 not yet recruiting, 1 recruiting. 26 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 26 | Completed 21, Unknown 3, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 3 | Completed 3 |
Follow Placebo Patch: new trials by email Literature Review of Placebo Patch trials Research Report on Placebo Patch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lidocaine Patch for Epidural Placement Pain in Laboring Women Lidocaine patch 4%, Placebo Patch, 1% Lidocaine Skin Wheal - Needle Phobia | Phase 3 | Recruiting | Ohio State University | 66 | 2026-10-07 | 2026-10-23 |
| Lidocaine Patch and Lower Third Molar Lidocaine patch, placebo patch - Impacted Third Molar Tooth | Phase 3 | Not yet recruiting | Fayoum University | 21 | 2026-01-01 | 2026-01-09 |
| Phase III Trial to Evaluate the Efficacy and Safety in Patients With Ankle Sprains. Esflurbiprofen Topical System (EFTS), Placebo Patch - Ankle Sprains | Phase 3 | Completed | Teikoku Seiyaku Co., Ltd. | 69 | 2025-03-31 | 2025-11-26 |
| Lidocaine Patches After Cesarean Section Lidocaine patch, Placebo patch - Postoperative Pain, Obstetric Pain | Phase 3 | Completed | Yale University | 93 | 2021-10-10 | 2024-11-06 |
| A 12-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Osteoarthritis Pain of the Knee Diclofenac sodium active topical patch, Placebo patch - Osteoarthritis Pain of the Knee | Phase 3 | Completed | Noven Pharmaceuticals, Inc. | 370 | 2020-12-29 | 2025-09-04 |
| Efficacy of Nicotine in Preventing COVID-19 Infection Nicotine patch, Placebo patch - Covid19, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 1633 | 2020-10-22 | 2021-02-17 |
| Pre-emptive Topical Lidocaine 5% Plaster for Prevention of Post-craniotomy Pain Lidocaine 5% patch, Placebo patch - Postoperative Pain, Lidocaine | Phase 3 | Unknown | Beijing Tiantan Hospital | 180 | 2020-10-15 | 2020-10-20 |
| Study of the Safety and Efficacy of DPI-386 Nasal Gel on Ocean-Going Vessels Scopolamine Transdermal Patch [Transderm Scop], Scopolamine, Placebo Patch - Prevention of Nausea Associated With Motion Sickness, Treatment of Nausea Associated With Motion Sickness | Phase 3 | Unknown | Naval Aeromedical Research Unit, Dayton | 320 | 2019-04-01 | 2019-04-19 |
| Herbal Patch for Overactive Bladder herbal patch, placebo patch - Overactive Bladder Syndrome | Phase 2 / Phase 3 | Completed | En Chu Kong Hospital | 66 | 2018-05-14 | 2019-10-25 |
| Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair Buprenorphine, Placebo Patch, Multimodal Oral Scheme - Rotator Cuff Tear, Rotator Cuff Injury | Phase 2 / Phase 3 | Completed | Hospital Italiano de Buenos Aires | 50 | 2016-09-22 | 2021-04-08 |
| Rotigotine Versus Placebo As Double Blind Study To Evaluate The Efficacy In Early Stage Idiopathic Parkinson's Disease Patients Rotigotine, Placebo Patch - IDIOPATHIC PARKINSON'S DISEASE | Phase 3 | Completed | UCB Pharma | 249 | 2012-07-01 | 2015-08-11 |
| Rotigotine Versus Placebo, A Study To Evaluate The Efficacy In Advanced Stage Idiopathic Parkinson's Disease Patients Rotigotine, Placebo Patch, L-dopa - Idiopathic Parkinson's Disease | Phase 3 | Completed | UCB Pharma | 346 | 2012-07-01 | 2018-04-04 |
| Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation Varenicline, Bupropion, Nicotine patches - Nicotine Dependence | Phase 3 | Completed | Duke University | 282 | 2011-07-01 | 2017-11-14 |
| Rivastigmine in the Management of Delirium Rivastigmine transdermal patch, placebo patch - Delirium | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 23 | 2011-06-01 | 2016-07-20 |
| HKT-500 in the Treatment of Adult Patients With Ankle Sprain Ketoprofen Patch, Placebo Patch - Ankle Sprain | Phase 3 | Completed | Hisamitsu Pharmaceutical Co., Inc. | 240 | 2009-07-01 | 2015-06-04 |
| HKT-500 in Adult Patients With Shoulder Pain HKT-500 Ketoprofen Topical Patch, Placebo Patch - Pain | Phase 3 | Completed | Hisamitsu Pharmaceutical Co., Inc. | 368 | 2008-04-01 | 2015-06-04 |
| HKT-500 in Adult Patients With Ankle Sprain HKT-500 Ketoprofen Topical Patch, Placebo Patch - Ankle Sprain | Phase 3 | Completed | Hisamitsu Pharmaceutical Co., Inc. | 260 | 2008-04-01 | 2015-06-04 |
| HKT-500 in Adult Patients With Osteoarthritis (OA) Knee Pain ketoprofen Patch, Placebo Patch - Osteoarthritis of the Knee | Phase 3 | Completed | Hisamitsu Pharmaceutical Co., Inc. | 380 | 2007-09-01 | 2015-06-04 |
| Methylphenidate Transdermal System (MTS) in the Treatment of Adult ADHD Methylphenidate Transdermal System (MTS), placebo patch - Attention Deficit Hyperactivity Disorder | Phase 3 | Completed | University of Utah | 92 | 2007-06-01 | 2015-01-16 |
| Endometrial Safety Study of Transdermal Testosterone (300 Mcg/Day) in Naturally Postmenopausal Women Testosterone Transdermal System, Placebo patch - Hypoactive Sexual Desire Disorder | Phase 3 | Completed | Warner Chilcott | 1271 | 2007-04-01 | 2011-12-15 |
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Sexual Dysfunctions, Psychological (5) · Ankle Injuries (3) · Pain (3) · Pain, Postoperative (2) · Parkinson Disease (2) · Alzheimer Disease (1) · Arthritis (1) · Athletic Injuries (1) · Attention Deficit Disorder with Hyperactivity (1) · COVID-19 (1) · Cigarette Smoking (1) · Delirium (1) · Diabetic Foot (1) · Emergencies (1) · Labor Pain (1)
Warner Chilcott (5) · Hisamitsu Pharmaceutical Co., Inc. (4) · Assistance Publique - Hôpitaux de Paris (2) · UCB Pharma (2) · Beijing Tiantan Hospital (1) · Duke University (1) · En Chu Kong Hospital (1) · Fayoum University (1) · Fundación Cardiovascular de Colombia (1) · Hospital Italiano de Buenos Aires (1) · Naval Aeromedical Research Unit, Dayton (1) · Noven Pharmaceuticals, Inc. (1) · Ohio State University (1) · Teikoku Seiyaku Co., Ltd. (1) · University of Utah (1)
United States (15) · Australia (3) · China (3) · Canada (2) · France (2) · Argentina (1) · Colombia (1) · Germany (1) · Taiwan (1)
Johna Lucas, MD (4) · Kenichi Furuta (2) · Arturo Orduz, MD (1) · Audrey Merriam, MD, MS (1) · Carlos A Calderon, PhD (1) · Christian F Rueda-Clausen, MD (1) · Christopher Arkfeld, MD (1) · Daniel J Smith, PhD (1) · F. Joseph McClernon, Ph.D. (1) · Fang Luo, MD (1) · Federico A Silva, MD (1) · Frederick W. Reimherr, MD (1) · Jaime Matute, MD (1)
PMID 17897470, PMID 18987368, PMID 22100691, PMID 27082828, PMID 28827011, PMID 39691748
2009 (1), P50DA027840 (1), R01AG017196 (1)