96 completed, 8 terminated, 7 recruiting, 6 withdrawn. 37 Phase 2, 31 Not applicable, 26 Phase 3, 23 Phase 4, 17 Phase 1.
Follow Placebo Patch: new trials by email Literature Review of Placebo Patch trials Research Report on Placebo Patch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Two-Part Study of the Effects of the X39 Patch on Circulating GHK and GHK-Cu Levels in Healthy Adults X39 Patch, Placebo Patch - GHK and GHK-Cu Blood Levels | Not applicable | Not yet recruiting | LifeWave, Inc. | 100 | 2027-01-01 | 2026-07-15 |
| Longterm Effects of a Biofield Patch on Anxiety, Sleep, and Energy Active dermal patch, Placebo patch - Anxiety, Sleep | Not applicable | Recruiting | Natural Immune Systems Inc | 40 | 2026-10-23 | 2026-11-12 |
| Lidocaine Patch for Epidural Placement Pain in Laboring Women Lidocaine patch 4%, Placebo Patch, 1% Lidocaine Skin Wheal - Needle Phobia | Phase 3 | Recruiting | Ohio State University | 66 | 2026-10-07 | 2026-10-23 |
| High-concentration Capsaicin Patch for the Prevention of Paclitaxel-induced Peripheral Neuropathy High Concentration Capsaicin Patch (HCCP), Placebo patch - Chemotherapy-induced Peripheral Neuropathy, CIPN - Chemotherapy-Induced Peripheral Neuropathy | Phase 4 | Not yet recruiting | Case Comprehensive Cancer Center | 240 | 2026-10-01 | 2026-09-22 |
| PBM Patch for Postoperative Pain Relief After Urological Surgery Super Vi PBM Patch - Soothing, Super Vi PBM Patch - Soothing EX, Placebo Patch - Urological Surgery, Photobiomodulation (PBM) | Not applicable | Not yet recruiting | National Taiwan University Hospital | 300 | 2026-07-01 | 2026-06-26 |
| Recovery and Early Sleep Tracking Using the SuperPatch REM Patch SuperPatch REM Patch, Sham REM Patch - Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder | Not applicable | Enrolling by invitation | SuperPatch Limited LLC | 20 | 2026-05-15 | 2026-08-25 |
| Lidocaine Patch and Lower Third Molar Lidocaine patch, placebo patch - Impacted Third Molar Tooth | Phase 3 | Not yet recruiting | Fayoum University | 21 | 2026-01-01 | 2026-01-09 |
| Effect of the Bioheat Patch on Pain Following the HyFoSy Procedure Bioheat Patch, Placebo Patch - Pelvic Pain, Infertility | Not applicable | Not yet recruiting | Assaf-Harofeh Medical Center | 80 | 2025-08-01 | 2025-07-30 |
| Transdermal Ethinyl Estradiol and Norelgestromin for Irregular Bleeding in Contraceptive Implant Users Transdermal Ethinyl Estradiol/Norelgestromin Patch, Placebo Patch - Menstruation Disturbances, Metrorrhagia | Phase 2 | Recruiting | Chulalongkorn University | 40 | 2025-07-29 | 2025-12-10 |
| Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery Buprenorphine Transdermal System, Placebo Patch - Pain, Postoperative, Ankle Fracture Surgery | Phase 4 | Recruiting | Jenna-Leigh Wilson | 100 | 2025-04-21 | 2026-04-06 |
| Phase III Trial to Evaluate the Efficacy and Safety in Patients With Ankle Sprains. Esflurbiprofen Topical System (EFTS), Placebo Patch - Ankle Sprains | Phase 3 | Completed | Teikoku Seiyaku Co., Ltd. | 69 | 2025-03-31 | 2025-11-26 |
| Role of Menopause in Thermoregulation Elagolix Oral Tablet, Estradiol patch, cellulose placebo - Menopause, Aging | Phase 4 | Recruiting | Penn State University | 24 | 2025-03-01 | 2026-10-02 |
| Beta-Adrenergic Modulation of Drug Cue Reactivity Propranolol, Nicotine Patch, Placebo Propranolol - Tobacco Use Disorder, Nicotine Dependence | Phase 4 | Recruiting | University of Oklahoma | 80 | 2024-11-26 | 2026-04-28 |
| NEUROCUPLE™ in TKA Patients to Enhance Pain Management NEUROCUPLE™ Patch, Placebo Patch - Total Knee Arthroplasty | Not applicable | Completed | nCap Medical | 156 | 2024-09-25 | 2026-11-05 |
| Is Nociceptive Processing Evoked by Heat Homeostatically Regulated: A Contact-heat Evoked Potentials Study Homeostatic Plasticity, Topical alone (Capsaicin 8% Patch), Placebo Patch - Healthy | Not applicable | Completed | Aalborg University | 18 | 2023-11-21 | 2024-05-16 |
| Lidocaine Patches in Elderly Patients With Traumatic Rib Fractures Placebo Patch, 4% Lidocaine Patch - Rib Fractures | Phase 4 | Terminated | Medical College of Wisconsin | 5 | 2023-10-01 | 2026-07-08 |
| Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin. Diode Laser fiber type Selective Stimulator, ZTlido 1.8 % Topical System, PeriCam PSI NR - Peripheral Neuropathy | Not applicable | Completed | University of Utah | 77 | 2023-09-01 | 2026-10-19 |
| The Use of Cannabinoid Patch for Knee Osteoarthritis Topical CBD Patch, Placebo Patch - Knee Osteoarthritis, CBD | Phase 2 | Withdrawn | Northwell Health | 2022-10-01 | 2023-01-19 | |
| Evaluation of the Dexmedetomidine Transdermal Systems for Postoperative Analgesia Following Abdominoplasty DMTS Patch, Placebo Patch - Pain, Postoperative | Phase 2 | Terminated | Teikoku Pharma USA, Inc. | 179 | 2022-07-07 | 2025-12-24 |
| Use of Aromatherapy in Conjunction With Physical/Occupational Therapy in an Acute Care Setting Lavender Oil, Mandarin Oil, Peppermint oil - Suffering, Physical, Nausea | Phase 1 | Completed | The University of Texas Health Science Center at San Antonio | 165 | 2022-05-16 | 2026-06-16 |
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Tobacco Use Disorder (14) · Pain (12) · Smoking Cessation (10) · Osteoarthritis, Knee (7) · Pain, Postoperative (7) · Sexual Dysfunctions, Psychological (5) · Ankle Injuries (4) · Cigarette Smoking (4) · Osteoarthritis (4) · Chronic Pain (3) · Delirium (3) · Memory Disorders (3) · Neuralgia (3) · Schizophrenia (3) · Stress Disorders, Post-Traumatic (3)
Hisamitsu Pharmaceutical Co., Inc. (7) · Duke University (5) · Warner Chilcott (5) · McNeil AB (4) · University of Wisconsin, Madison (4) · Assistance Publique - Hôpitaux de Paris (3) · National Institute on Drug Abuse (NIDA) (3) · Noven Pharmaceuticals, Inc. (3) · University of Colorado, Denver (3) · ZARS Pharma Inc. (3) · Aalborg University (2) · Chattem, Inc. (2) · Endo USA Inc., a Keenova Therapeutics Company (2) · Massachusetts General Hospital (2) · Merck Sharp & Dohme LLC (2)
United States (86) · Germany (7) · Canada (5) · China (5) · Israel (4) · Australia (3) · Denmark (3) · France (3) · Taiwan (2) · Thailand (2) · Argentina (1) · Austria (1) · Colombia (1) · Czechia (1) · Netherlands (1)
Elisabeth Kruse, PhD (4) · Johna Lucas, MD (4) · Kenichi Furuta (3) · Avner Shemer, M.D. (2) · Daniel J Hogan, MD (2) · Peter J Schmidt, M.D. (2) · Alan S Lewis, MD, PhD (1) · Albert Powers, MD, PhD (1) · Alex Bekker, MD, PhD (1) · Amy Janes, Ph.D. (1) · Antonella Cianferoni, MD, PhD (1)
PMID 28044059, PMID 28786978, PMID 30184299, PMID 34035477, PMID 37230961, PMID 11681767, PMID 12377405, PMID 12478880, PMID 12509650, PMID 12832959, PMID 12946238, PMID 15564950, PMID 17897470, PMID 18987368, PMID 19339135, PMID 19822404, PMID 21846661, PMID 22100691, PMID 22531485, PMID 22854911, PMID 22886871, PMID 27082828, PMID 28158151, PMID 28416813, PMID 28807894, PMID 28827011, PMID 29693495, PMID 31100455, PMID 31810978, PMID 32034447, PMID 32151567, PMID 32559759, PMID 32600406, PMID 33913104, PMID 34507574, PMID 34611902, PMID 34665204, PMID 35020462, PMID 35809362, PMID 37142273, PMID 37335995, PMID 37339441, PMID 38348917, PMID 39691748, PMID 40294815, PMID 40803048, PMID 41913970, PMID 8842510, PMID 9207632, PMID 9821833
P50DA027840 (3), 2005 (2), 2008 (1), 2009 (1), 2014 (1), K23MH116339 (1), P50MH099910 (1), R00MH109667 (1), R01AG013241 (1), R01AG017196 (1), R01AG047992 (1), R01CA136918 (1), R01CA239309 (1), R01DA015365 (1), R01DA031006 (1)