16 completed, 1 withdrawn. 17 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 17 | Completed 16, Withdrawn 1 |
| Phase 2 | 4 | Completed 3, Withdrawn 1 |
Follow Placebo patch: new trials by email Literature Review of Placebo patch trials Research Report on Placebo patch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Aromatherapy in Conjunction With Physical/Occupational Therapy in an Acute Care Setting Lavender Oil, Mandarin Oil, Peppermint oil - Suffering, Physical, Nausea | Phase 1 | Completed | The University of Texas Health Science Center at San Antonio | 165 | 2022-05-16 | 2026-06-16 |
| Evoked Responses as Pharmacodynamic Biomarkers in Healthy and Schizophrenic Participants (MK-4334-007) Nicotine patch, MK-4334, Placebo patch - Cognitive Impairment Associated With Schizophrenia | Phase 1 | Completed | Merck Sharp & Dohme LLC | 38 | 2022-04-27 | 2024-11-29 |
| A Study to Assess Therapeutic Equivalence Between Test EMLA Patch With Marketed EMLA Patch in Healthy Subjects. EMLA test patch, EMLA current reference patch, Placebo Patch - Pain | Phase 1 | Completed | AstraZeneca | 32 | 2017-10-30 | 2017-11-14 |
| An Exploratory Study to Investigate the Inflammatory Response During a Cold Sore Episode Acyclovir patch, Placebo patch - Herpes Labialis | Phase 1 | Completed | GlaxoSmithKline | 60 | 2012-07-01 | 2014-07-16 |
| A Study Evaluating the Absorption Of Varenicline Through The Skin Following Once Daily Application Of A Patch For 14 Days varenicline free base patch, placebo patch - Smoking Cessation | Phase 1 | Completed | Pfizer | 45 | 2010-11-01 | 2011-10-14 |
| Safety, Tolerability and Pharmacokinetics of MK-0873 Following Patch Application in Healthy Participants and Psoriasis Participants (MK-0873-020) MK-0873 Patch, MK-0873 Cream, Placebo Patch - Plaque Psoriasis | Phase 1 | Completed | Merck Sharp & Dohme LLC | 42 | 2010-05-01 | 2019-02-08 |
| Aging and Estrogen on Cortical Function Estradiol oral capsule, transderman estrogen patch, trasdermal placebo patch - Memory Loss, Cognitive Changes | Phase 1 / Phase 2 | Completed | Massachusetts General Hospital | 38 | 2009-11-01 | 2018-08-22 |
| Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction Quit smoking, Nicotine patch, Placebo Patch - Smoking | Phase 1 | Completed | Duke University | 147 | 2009-03-01 | 2017-01-31 |
| Study of Capsaicin Patch for the Management of Peripheral Neuropathic Pain CAPNP, 50 ug/cm2 capsaicin patch, CAPNP, 100 ug/cm2 capsaicin patch, 0.075% capsaicin cream - Peripheral Nerve Injury, Postherpetic Neuralgia | Phase 1 / Phase 2 | Completed | Samyang Biopharmaceuticals Corporation | 60 | 2009-02-01 | 2017-05-01 |
| Civamide Patch Safety, Tolerability and PK Study Zucapsaicin, Placebo patch - Healthy Volunteers | Phase 1 | Completed | Winston Laboratories | 39 | 2008-09-01 | 2011-06-10 |
| Photoirritation and Photoallergic Potential of a New Nicotine Patch Nicotine Patch, Placebo Patch, No Patch Control - Smoking Cessation | Phase 1 | Completed | McNeil AB | 43 | 2005-08-01 | 2012-07-10 |
| Cumulative Skin Irritation Potential of a New 15 mg Nicotine Patch Nicotine Patch, Nicotine Patch Comparator, Placebo Patch - Smoking Cessation | Phase 1 | Completed | McNeil AB | 42 | 2005-05-01 | 2012-06-29 |
| Skin Sensitization Potential of a New Nicotine Patch Nicotine Patch, Placebo Patch - Smoking Cessation | Phase 1 | Completed | McNeil AB | 257 | 2005-05-01 | 2012-07-10 |
| Cumulative Skin Irritation Potential of a New 25 mg Nicotine Patch Nicotine Patch, Placebo Patch, SLS Comparator Patch - Smoking Cessation | Phase 1 | Completed | McNeil AB | 42 | 2005-05-01 | 2012-07-10 |
| The Effects of Reproductive Hormones on Mood and Behavior Leuprolide Acetate 3.75, Estradiol, Progesterone - Healthy Volunteers | Phase 1 / Phase 2 | Completed | National Institute of Mental Health (NIMH) | 100 | 1994-06-09 | 2022-03-22 |
| A Treatment Study for Premenstrual Syndrome (PMS) Leuprolide, Estradiol Patches, Progesterone - Premenstrual Syndrome, Menstruation Disturbances | Phase 1 | Completed | National Institute of Mental Health (NIMH) | 60 | 1992-08-11 | 2023-03-02 |
| Safety and Tolerability of a Therapeutic DNA Dendritic Cell Vaccine in HIV-Infected Children, Adolescents, and Young Adults DermaVir patch, Placebo patch - HIV Infections | Phase 1 / Phase 2 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-11-01 |
Smoking Cessation (5) · Pain (3) · Behavior (1) · Depression (1) · Erythema (1) · HIV Infections (1) · Herpes Labialis (1) · Memory Disorders (1) · Menstruation Disturbances (1) · Mood Disorders (1) · Nausea (1) · Neuralgia, Postherpetic (1) · Peripheral Nerve Injuries (1) · Premenstrual Syndrome (1) · Smoking (1)
McNeil AB (4) · Merck Sharp & Dohme LLC (2) · National Institute of Mental Health (NIMH) (2) · AstraZeneca (1) · Duke University (1) · GlaxoSmithKline (1) · Massachusetts General Hospital (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Pfizer (1) · Samyang Biopharmaceuticals Corporation (1) · The University of Texas Health Science Center at San Antonio (1) · Winston Laboratories (1)
United States (8) · Germany (6) · South Korea (1)
Elisabeth Kruse, PhD (4) · Peter J Schmidt, M.D. (2) · Bianca Gonzales, OTR, CNT, EdD, MOT (1) · Elizabeth McFarland, MD (1) · Hans M.L. Spiegel, MD (1) · Janet E Hall, MD (1) · Joseph McClernon, Ph.D (1) · Ram Yogev, MD (1) · Scott B Phillips, M.D. (1) · Willaim Borkowsky, MD (1)
PMID 28044059, PMID 28786978, PMID 30184299, PMID 34035477, PMID 28158151, PMID 28416813, PMID 33913104
2005 (2), R01AG013241 (1)