39 completed, 9 unknown, 5 terminated, 2 withdrawn. 56 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 56 | Completed 39, Unknown 9, Terminated 5, Withdrawn 2, Not yet recruiting 1 |
Follow Donepezil: new trials by email Literature Review of Donepezil trials Research Report on Donepezil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Therapeutic Strategies With Cholinesterase Inhibitors (SOS TRIAL) cholinesterase inhibitors (CI) (donepezil, galantamine or rivastigmine) - Alzheimer Disease, Cholinesterase Inhibitors | Phase 4 | Not yet recruiting | University Hospital, Bordeaux | 1205 | 2024-06-01 | 2023-10-06 |
| Efficiency of Donepezil in Elderly Patients for Prevention of POCD Dysfunction Donepezil, Placebo - Total Knee Arthroplasty, Fracture of Head of Femur Articular Displaced | Phase 4 | Unknown | RenJi Hospital | 360 | 2020-06-14 | 2020-12-29 |
| Monitoring Anti-Dementia Drugs by Serum Levels Donepezil, Memantine, Measurement of serum level of anti-dementia drug - Dementia, Dementia With Lewy Bodies | Phase 4 | Completed | Zealand University Hospital | 132 | 2020-02-04 | 2025-02-10 |
| A Based on PEEG and PET Study of Anxiolytic Treatment to Improve Cognitive Function in Patients With Alzheimer Disease Tandospirone Citrate, Donepezil Hydrochloride - Alzheimer Disease, Cognitive Function | Phase 4 | Unknown | Zhejiang Provincial People's Hospital | 30 | 2017-05-20 | 2017-05-12 |
| Effect of Acetylcholinesterase Inhibitors on the Gait of the Patients With Parkinson Disease Donepezil, Placebos - Parkinson Disease | Phase 4 | Unknown | Kyung Hee University Hospital | 20 | 2017-04-11 | 2018-03-07 |
| Safety and Efficacy of Donepezil in Mild to Moderate Alzheimer's Disease Donepezil - Alzheimer's Disease | Phase 4 | Completed | Beijing Friendship Hospital | 241 | 2016-04-01 | 2024-08-23 |
| A Post-Marketing Clinical Study of Aricept in Patients With Dementia With Lewy Bodies (DLB) E2020, Placebo - Dementia, Lewy Body, Lewy Body Disease | Phase 4 | Completed | Eisai Co., Ltd. | 160 | 2015-03-01 | 2019-01-08 |
| The Impact of Arousal Threshold in Obstructive Sleep Apnea Donepezil, placebo - Obstructive Sleep Apnea | Phase 4 | Completed | University of California, San Diego | 44 | 2014-09-01 | 2019-08-08 |
| Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease donepezil HCL, Placebo - Genetic Risk for Alzheimer's Disease | Phase 4 | Completed | The Cleveland Clinic | 89 | 2014-05-01 | 2023-08-30 |
| Safety and Efficacy of Donepezil HCl 23 mg in Patients With Moderate to Severe Alzheimer's Disease Donepezil HCL - Alzheimer's Disease | Phase 4 | Completed | Eisai Korea Inc. | 171 | 2014-02-01 | 2016-06-27 |
| Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly Donepezil - Alzheimer Disease, Mild Cognitive Impairment | Phase 4 | Completed | New York State Psychiatric Institute | 121 | 2013-10-01 | 2020-07-13 |
| A Study of Donepezil Hydrochloride in Patients With Dementia Associated With Cerebrovascular Disease Donepezil hydrochloride, Donepezil matching placebo - Dementia Associated With Cerebrovascular Disease | Phase 4 | Completed | Eisai Co., Ltd. | 302 | 2013-08-05 | 2020-01-10 |
| Effect of Memantine Oral Pump on Language in Patients With Probable Alzheimer's Disease Ebixa, donepezil - Alzheimer's Disease, Dementia | Phase 4 | Unknown | Konkuk University Medical Center | 188 | 2013-01-01 | 2014-08-13 |
| Donepezil Compared to Placebo in Patients With Chronic Neuropathic Pain Donepezil, Placebo - Neuropathic Pain | Phase 4 | Terminated | Wake Forest University | 5 | 2012-12-01 | 2021-03-02 |
| Olfactory Deficits in MCI as Predictor of Improved Cognition on Donepezil Donepezil, Atropine - Mild Cognitive Impairment | Phase 4 | Completed | New York State Psychiatric Institute | 41 | 2012-08-01 | 2018-07-09 |
| Treatment of Delirium in the Elderly With Donepezil: a Double-blind, Randomized, Placebo-controlled Clinical Trial Donepezil - Elderly, Delirium of Unknown (Axis III) Etiology | Phase 4 | Terminated | University of Sao Paulo | 19 | 2012-08-01 | 2018-05-03 |
| Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia Donepezil, Single-letter training, Uncrowd training - Amblyopia | Phase 4 | Completed | Dennis Levi | 20 | 2012-05-01 | 2019-01-17 |
| The Effect of Donepezil on Gait and Balance in Parkinson's Disease Donepezil, Placebo - Parkinson's Disease | Phase 4 | Completed | Oregon Health and Science University | 21 | 2011-12-01 | 2021-10-05 |
| Combination Treatment Study for Memory Impairment and Depression Donepezil, Placebo, Citalopram - Depression, Mild Cognitive Impairment | Phase 4 | Completed | New York State Psychiatric Institute | 86 | 2011-09-01 | 2017-10-17 |
| A Double-blind, Placebo-controlled Trial of Donepezil Adjunctive Treatment for Cognitive Impairment in Schizophrenia Donepezil, placebo - Impaired Cognition, Schizophrenia | Phase 4 | Unknown | Central South University | 80 | 2011-06-01 | 2011-12-13 |
Showing 20 of 56. Sign in to see all of them.
Alzheimer Disease (25) · Cognitive Dysfunction (8) · Dementia (8) · Cognition Disorders (4) · Delirium (3) · Parkinson Disease (3) · Sleep Apnea Syndromes (3) · Sleep Apnea, Obstructive (3) · Anosmia (2) · Depression (2) · Diabetic Neuropathies (2) · Lewy Body Disease (2) · Postoperative Complications (2) · Schizophrenia (2) · Stroke (2)
Eisai Inc. (7) · Eisai Korea Inc. (4) · Eisai Co., Ltd. (3) · New York State Psychiatric Institute (3) · Associacao Fundo de Incentivo a Psicofarmcologia (2) · University of Pittsburgh (2) · Wake Forest University (2) · BeerYaakov Mental Health Center (1) · Beijing Friendship Hospital (1) · Central South University (1) · Dennis Levi (1) · Duke University (1) · Duke-NUS Graduate Medical School (1) · Ever Neuro Pharma GmbH (1) · Gabinete Berthier y MartÃnez (1)
United States (26) · South Korea (7) · Brazil (3) · China (3) · Japan (2) · Spain (2) · United Kingdom (2) · Austria (1) · Canada (1) · Denmark (1) · France (1) · Germany (1) · Israel (1) · Philippines (1) · Singapore (1)
Anita Murthy (2) · Davangere Devanand, M.D. (2) · Jihee Mun (2) · Malaz Boustani, MD, MPH (2) · Alistair Burns (1) · Bruce G. Pollock, MD, PhD (1) · Clive Holmes (1) · Cuibai Wei, MD,PhD (1) · Dalva Poyares, MD, PhD (1) · Davangere Devanand, MD (1) · Dennis M Levi, OD, PhD (1) · Diansan Su (1) · Dieter Meier, MD (1) · Eric J. Lenze, MD (1) · Gary W. Small, MD (1)
PMID 16494088, PMID 17914039, PMID 18198262, PMID 18251622, PMID 18667813, PMID 18971479, PMID 19210951, PMID 19874395, PMID 19917989, PMID 22281004, PMID 23408503, PMID 24078735, PMID 24144505, PMID 24290367, PMID 24299497, PMID 24315979, PMID 25079803, PMID 26795874, PMID 27442715, PMID 28824369, PMID 29635383, PMID 30037778, PMID 30794310, PMID 31985467, PMID 32333591, PMID 33189083, PMID 34627332, PMID 40034344
R01NS057594 (2), 2017 (1), K23MH064196 (1), R01AG018487 (1), R01AG040093 (1), R01AG041795 (1), R01MH035182 (1), R01MH043832 (1), R21MH061801 (1)