49 completed, 7 unknown, 5 terminated, 3 recruiting. 66 Phase 3, 14 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 66 | Completed 49, Unknown 7, Terminated 5, Recruiting 3, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 14 | Completed 7, Terminated 3, Recruiting 2, Not yet recruiting 1, Unknown 1 |
Follow Diclofenac: new trials by email Literature Review of Diclofenac trials Research Report on Diclofenac
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Topical Dexamethasone/Diclofenac Hydrogel for Postoperative Pain and Swelling in Facial Soft Tissue Injuries Poloxmer F-127 Hydrogel with Dexamethasone/Diclofenac, Plain Pluronic F-127 Hydrogel Placebo - Facial Injuries, Pain | Phase 2 / Phase 3 | Recruiting | Thamar University | 52 | 2026-01-01 | 2026-10-02 |
| Diclofenac for Prevention of Post-ERC Pancreatitis Diclofenac - Common Bile Duct Diseases | Phase 2 / Phase 3 | Not yet recruiting | Karolinska Institutet | 1000 | 2026-01-01 | 2025-08-13 |
| Counterpain PXM Versus Diclofenac Versus Piroxicam Piroxicam plus Counterirritant (brand name Counterpain® PXM)., Diclofenac Sodium 10 mg (Brand Name Hotin® DCL), Piroxicam 0.5% (Brand name Pirofel® gel) - Ankle Sprain, Back Pain | Phase 3 | Completed | Taisho Pharmaceutical Indonesia | 180 | 2025-11-04 | 2026-03-16 |
| The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament Diclofenac Sodium, Calcium hydroxide - Endodontic Disease, Pulp Disease, Dental | Phase 2 / Phase 3 | Recruiting | British University In Egypt | 48 | 2025-11-01 | 2025-05-30 |
| Diclofenac Gel in the Treatment of Cervicogenic Headache Diclofenac 1% Topical, Petroleum Jelly - Cervicogenic Headache | Phase 3 | Withdrawn | Loma Linda University | 2023-12-01 | 2025-01-23 | |
| A Comparison of Recovery After Impacted Wisdom Tooth Removal serratiopeptidase, Escin, Conventional drugs - Impacted Mandibular Third Molar Extraction, Post Operative Complications | Phase 3 | Completed | University of Science and Technology, Yemen | 24 | 2023-11-30 | 2025-12-26 |
| Topical Treatment for TMJ Arthralgia Hydrocortisone 2.5%, Diclofenac 1% topical - TMJ Pain | Phase 3 | Recruiting | University of the Pacific | 90 | 2023-06-01 | 2024-12-11 |
| COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA Lacosamide 50 MG Oral Tablet [Vimpat], Codeine Phosphate, Diclofenac Sodium - Sciatica Acute, Sciatica | Phase 3 | Completed | Pakistan Institute of Medical Sciences | 120 | 2021-09-28 | 2022-11-23 |
| To Evaluate the Superiority of Fixed Combination (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to Voltaren® (Diclofenac Sodium 50mg) in the Treatment of Acute Postural Low Back Pain. orphenadrine, acetaminophen, caffeine and diclofenac sodium, Diclofenac Sodium 50 MG, Placebo (for experimental drug) - Postural Low Back Pain, Mechanical Low Back Pain | Phase 3 | Unknown | Ache Laboratorios Farmaceuticos S.A. | 110 | 2021-01-01 | 2020-09-03 |
| 5% KOH Solution vs. Placebo and Diclofenac Gel for the Treatment of Actinic Keratosis Solcera, Placebo, Solaraze - Actinic Keratosis | Phase 3 | Completed | Infectopharm Arzneimittel GmbH | 631 | 2020-10-14 | 2024-03-05 |
| A Study to Assess Efficacy and Safety of the Ketoprofen vs Diclofenac Ketoprofen topical, Diclofenac Topical - Osteoarthritis | Phase 3 | Completed | Handok Inc. | 236 | 2020-03-20 | 2021-01-20 |
| Clinical Trial With Diclofenac Sodium Medicated Plaster in Patients With Impact Injuries of the Limbs Diclofenac Sodium 140 mg medicated plaster, Diclofenac epolamine (DIEP) 180mg medicated plaster, Flector, Placebo - Trauma Injury, Inflammation | Phase 3 | Completed | Fidia Farmaceutici s.p.a. | 214 | 2018-05-25 | 2023-10-02 |
| Therapeutic Equivalence of Diclofenac Sodium Gel 3% vs Solaraze ® in the Treatment of Actinic Keratosis Diclofenac Sodium Gel, Solaraze 3% Topical Gel, Placebo - Actinic Keratoses | Phase 3 | Completed | Encube Ethicals Pvt. Ltd. | 655 | 2018-01-12 | 2019-02-01 |
| Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip Fasinumab, Diclofenac, Celecoxib - Osteoarthritis, Knee, Osteoarthritis, Hip | Phase 3 | Completed | Regeneron Pharmaceuticals | 1650 | 2017-10-26 | 2023-02-24 |
| Tramadol/Diclofenac Fixed-dose Combination Phase III Trial in Acute Pain After Third Molar Extraction Tramadol/Diclofenac 50/50, Tramadol/Diclofenac 25/25, Tramadol 50 - Acute Pain | Phase 3 | Completed | Grünenthal GmbH | 1151 | 2017-08-26 | 2019-07-24 |
| Comparative Study Between the Effect of Diclofanic and Ketorolac in Post Tonsillectomy Pain Management diclofenac, ketorolac - Pain, Acute | Phase 2 / Phase 3 | Completed | Assiut University | 100 | 2017-01-31 | 2020-07-14 |
| Effect of Preoperative Diclofenac Potassium on Postoperative Endodontic Pain Diclofenac Potassium 50mg Tab., Placebo - Pulpitis - Irreversible | Phase 2 / Phase 3 | Completed | Cairo University | 70 | 2016-12-01 | 2018-04-09 |
| Oral Hyoscine Butyl Bromide Versus Diclofenac Potassium Before Office Hysteroscopy diclofenac potassium, hyoscine butyl bromide, placebo - Endoscopy | Phase 2 / Phase 3 | Completed | Assiut University | 129 | 2016-10-01 | 2018-01-05 |
| Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success Diclofenac Potassium 50mg Tab, Placebo - Pulpitis - Irreversible, Anesthesia, Local | Phase 2 / Phase 3 | Completed | Cairo University | 70 | 2016-10-01 | 2018-07-19 |
| Diclofenac Potassium on IANB Efficacy in Symptomatic Irreversible Pulpitis Diclofenac potassium, Placebo - Irreversible Pulpitis | Phase 2 / Phase 3 | Unknown | Cairo University | 68 | 2016-07-01 | 2017-05-23 |
Showing 20 of 66. Sign in to see all of them.
Osteoarthritis (8) · Pain (8) · Acute Pain (5) · Pain, Postoperative (5) · Ankle Injuries (4) · Keratosis, Actinic (4) · Osteoarthritis, Knee (3) · Inflammation (2) · Low Back Pain (2) · Osteoarthritis, Hip (2) · Pulpitis (2) · Soft Tissue Injuries (2) · Toothache (2) · Accidental Injuries (1) · Anemia (1)
Cairo University (7) · Cerimon Pharmaceuticals (4) · Pfizer (4) · Assiut University (3) · Novartis (3) · Iroko Pharmaceuticals, LLC (2) · Mika Pharma GmbH (2) · Xanodyne Pharmaceuticals (2) · Ache Laboratorios Farmaceuticos S.A. (1) · Actavis Inc. (1) · Ain Shams University (1) · Anchen Pharmaceuticals, Inc (1) · Bagcilar Training and Research Hospital (1) · Baskent University (1) · Bausch Health Americas, Inc. (1)
United States (24) · Egypt (12) · Germany (9) · Russia (4) · France (2) · Italy (2) · Spain (2) · United Kingdom (2) · Yemen (2) · Austria (1) · Chile (1) · Croatia (1) · Hungary (1) · India (1) · Indonesia (1)
Alan Kivitz, MD (2) · Antoinette A Pragalos, MD (2) · Bradley Swenson, MD (2) · Brandon Essink, MD (2) · Cindy Tuten, MD (2) · Curtis S Horn, MD (2) · Dan Levitt, MD (2) · David Bouda, MD (2) · Douglas R Schumacher, MD (2) · Eddie Armas, MD (2) · Eli M Roth, MD (2) · Enrico Jones, MD (2) · Francisco Chevres, MD (2) · Gary Tarshis, MD (2)
PMID 22587481, PMID 16331769, PMID 19922878, PMID 20804444, PMID 23852695, PMID 24465046, PMID 25050589, PMID 25913498, PMID 26554876, PMID 28178072, PMID 28345425, PMID 29247809, PMID 29492863, PMID 30936738, PMID 31353997, PMID 32086778, PMID 32221866, PMID 33053612, PMID 36877132, PMID 39004211, PMID 40001000, PMID 40996107
2009 (1), 2015 (1), 2017 (1)